Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1551-1559

  Foster, John G ^a   Carter, Edward ^a   Kilty, Iain ^b   MacKenzie, Amanda B ^a   Ward, Stephen G ^a  

^a University of Bath   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIMYCIN A1; ION CHANNEL; L SELECTIN; PHOSPHATIDYLSERINE; PURINERGIC P2X7 RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; SUPEROXIDE; UBIQUINOL CYTOCHROME C REDUCTASE;

APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL LOSS; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; INHIBITION KINETICS; PATCH CLAMP; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; WHOLE CELL;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MEMBRANE; CELLS, CULTURED; DOWN-REGULATION; HEK293 CELLS; HUMANS; JURKAT CELLS; L-SELECTIN; MITOCHONDRIA; RECEPTORS, PURINERGIC P2X7; SUPEROXIDES; UP-REGULATION;

EID: 84873558780     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201510     Document Type: Article

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