ZBP-89, a kruppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter

Molecular and Cellular Biology

Volumn 16, Issue 12, 1996, Pages 6644-6653

  Merchant, Juanita L ^a,b,d   Iyer, Gaitry R ^a   Taylor, Brigit R ^a   Kitchen, John R ^b   Mortensen, Eric R ^a   Wang, Ziyuan ^b   Flintoft, Rebecca J ^b   Michel, Jeffrey B ^c   Bassel Duby, Rhonda ^c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

^d 3510 MSRB I ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; GASTRIN; GENE PRODUCT; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR SP1; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; KRUPPEL LIKE FACTOR; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE INDUCTION; HORMONE RESPONSIVE ELEMENT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; REPRESSOR GENE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; DNA-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; GASTRINS; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0029658599     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.12.6644     Document Type: Article

References (41)

1. Ackerman, S. L., A. G. Minden, G. T. Williams, C. Bobonis, and C.-Y. Yeung. 1993. Functional significance of an overlapping consensus binding motif for Sp1 and Zif268 in the murine adenosine deaminase gene promoter. Proc. Natl. Acad. Sci. USA 88:7523-7527.
2. Attar, R. M., and M. Z. Gilman. 1992. Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. Mol. Cell. Biol. 12:2432-2443.
3. Bassel-Duby, R., M. D. Hernandez, M. A. Gonzalez, J. K. Krueger, and R. S. Williams. 1992. A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter. Mol. Cell. Biol. 12:5024-5032.
4. Biggin, M. D., and R. Tjian. 1989. A purified Drosophila homeodomain protein represses transcription in vitro. Cell 58:433-440.
5. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
6. Brand, S. J., and P. J. Fuller. 1988. Differential gastrin gene expression in rat gastrointestinal tract and pancreas during neonatal development. J. Biol. Chem. 263:5341-5347.
7. Bray, P., P. Lichter, H.-J. Thiesen, D. C. Ward, and I. B. Dawid. 1991. Characterization and mapping of human genes encoding zinc finger proteins. Proc. Natl. Acad. Sci. USA 88:9563-9567.
8. Chung, D. C., S. J. Brand, and L. G. Tillotson. 1995. Mutually exclusive interactions between factors binding to adjacent Sp1 and AT-rich elements regulate gastrin gene transcription in insulinoma cells. J. Biol. Chem. 270: 8829-8836.
9. Courey, A. J., and R. Tjian. 1992. Mechanisms of transcriptional control as revealed by studies of human transcription factor Sp1, p. 743-789. In S. L. McKnight, and K. R. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
10. Dingwall, C., and R. A. Laskey. 1991. Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16:478-481.
11. Drummond, I. A., S. L. Madden, P. Rohwer-Nutter, G. I. Bell, V. P. Sukhatme, and F. J. Rauscher III. 1992. Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WTI. Science 257: 674-678.
12. Feo, S., V. Antona, G. Barbieri, R. Passantino, L. Cali, and A. Giallongo. 1995. Transcription of the human β enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors. Mol. Cell. Biol. 15:5991-6002.
13. Grumont, R. J., J. Fecondo, and S. Gerondakis. 1994. Alternate RNA splicing of murine nfkbl generates a nuclear isoform of the p50 precursor NF-κB1 that can function as a transactivator of NF-κB-regulated transcription. Mol. Cell. Biol. 14:8460-8470.
14. Guan, K. L., and J. E. Dixon. 1991. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192:262-267.
15. Han, K., M. S. Levine, and J. L. Manley. 1989. Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell 56:573-583.
16. Jensen, R. T., J. D. Gardner, J.-P. Raufman, S. J. Pandol, J. L. Doppman, and M. J. Collen. 1983. Zollinger-Ellison syndrome: current concepts and management. Ann. Intern. Med. 98:59-75.
17. Kinzler, K. W., and B. Vogelstein. 1990. The GL1 gene encodes a nuclear protein which binds specific sequences in the human genome. Mol. Cell. Biol. 10:634-642.
18. Kitadai, Y., W. Yasui, H. Yokozaki, H. Kuniyasu, K. Haruma, G. Kajiyama, and E. Tahara. 1992. The level of a transcription factor Sp1 is correlated with the expression of EGF receptor in human gastric carcinomas. Biochem. Biophys. Res. Commun. 189:1342-1349.
19. Lemaigre, F. P., D. A. Lafontaine, S. J. Courtois, S. M. Durviaux, and G. G. Rousseau. 1990. Sp1 can displace GHF-1 from its distal binding site and stimulate transcription from the growth hormone gene promoter. Mol. Cell. Biol. 10:1811-1814.
20. Levine, M., and J. L. Manley. 1989. Transcriptional repression of eukaryotic promoters. Cell 59:405-408.
21. Madden, S. L., D. M. Cook, J. F. Morris, A. Gashler, V. P. Sukhatme, and F. J. Rauscher III. 1991. Transcriptional repression mediated by the WT1 Wilms tumor gene product. Science 253:1550-1553.
22. Madden, S. L., and F. J. Rauscher III. 1993. Positive and negative regulation of transcription and cell growth mediated by the EGR family of zinc-finger gene products. Ann. N. Y. Acad. Sci. 684:75-84.
23. Merchant, J. L., B. Demediuk, and S. J. Brand. 1991. A GC-rich element confers epidermal growth factor responsiveness to transcription from the gastrin promoter. Mol. Cell. Biol. 11:2686-2696.
24. Merchant, J. L., A. Shiotani, E. Mortensen, D. Shumaker, and D. Abraczinskas. 1995. EGF stimulation of the human gastrin promoter requires Sp1. J. Biol. Chem. 270:6314-6319.
25. Miller, I. J., and J. J. Bieker. 1993. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins. Mol. Cell. Biol. 13:2776-2786.
26. Parmacek, M. S., H. S. Ip, F. Jung, T. Shen, J. F. Martin, A. J. Vora, E. N. Olson, and J. M. Leiden. 1994. A novel myogenic regulatory circuit controls slow/cardiac troponin C gene transcription in skeletal muscle. Mol. Cell. Biol. 14:1870-1885.
27. Sauer, F., J. D. Fondell, Y. Ohkuma, R. G. Roeder, and H. Jackle. 1995. Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ. Nature (London) 375:162-164.
28. Sauer, F., and H. Jackle. 1991. Concentration-dependent transcriptional activation or repression by Kruppel from a single binding site. Nature (London) 353:563-566.
29. Schindler, C., X. Y. Fu, T. Improta, R. Aebersold, and J. E. Darnell, Jr. 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon α. Proc. Natl. Acad. Sci. USA 89:7836-7839.
30. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:6420.
31. Shiotani, A., and J. L. Merchant. 1995. cAMP regulates gastrin gene expression. Am. J. Physiol. 269:G458-G464.
32. Singh, H., R. G. Clerc, and J. H. LeBowitz. 1989. Molecular cloning of sequence-specific DNA binding proteins using recognition site probes. Bio-Techniques 7:252-261.
33. Singh, H., J. H. LeBowitz, A. S. Baldwin, Jr., and P. A. Sharp. 1988. Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell 52:415-423.
34. Sukhatme, V. P., X. Cao, L. C. Chang, C.-H. Tsai-Morris, D. Stamenkovich, P. C. P. Ferreira, D. R. Cohen, S. A. Edwards, T. B. Shows, T. Curran, M. M. LeBeau, and E. D. Adamson. 1988. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53:37-43.
35. Tillotson, L. G., T. C. Wang, and S. J. Brand. 1994. Activation of gastrin transcription in pancreatic insulinoma cells by a CACC promoter element and a 70-kDa sequence-specific DNA-binding protein. J. Biol. Chem. 269: 2234-2240.
36. Walsh, J. H. 1994. Gastrointestinal hormones, p. 1-128. In L. R. Johnson, D. H. Alpers, J. Christensen, E. D. Jacobson, and J. H. Walsh (ed.), Physiology of the gastrointestinal tract. Raven Press, New York.
37. Wang, T. C., and S. J. Brand. 1990. Islet cell-specific regulatory domain in the gastrin promoter contains adjacent positive and negative DNA elements. J. Biol. Chem. 265:8908-8914.
38. Wang, Y., J. A. Kobori, and L. Hood. 1993. The htβ gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expression. Mol. Cell. Biol. 13:5691-5701.
39. Wu, Y., G. C. Fraizer, and G. F. Saunders. 1995. GATA-1 transactivates the WT1 hematopoietic specific enhancer. J. Biol. Chem. 270:5944-5949.
40. Yamauchi, K., K. Holt, and J. E. Pessin. 1993. Phosphatidylinositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription. J. Biol. Chem. 268:14597-14600.
41. Yu, C.-Y., K. Motamed, J. Chen, A. D. Bailey, and C.-K. J. Shen. 1991. The CACC box upstream of human embryonic epsilon globin gene binds Sp1 and is a functional promoter element in vitro and in vivo. J. Biol. Chem. 266: 8907-8915.