-
2
-
-
77349113764
-
Important role of integrins in the cancer biology
-
Rathinam R, Alahari SK. Important role of integrins in the cancer biology. Cancer Metastasis Rev 2010;29:223-37.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 223-237
-
-
Rathinam, R.1
Alahari, S.K.2
-
3
-
-
35848938723
-
The integrin-growth factor receptor duet
-
Alam N, Goel HL, Zarif MJ, Butterfield JE, Perkins HM, Sansoucy BG, et al. The integrin-growth factor receptor duet. J Cell Physiol 2007;213: 649-53.
-
(2007)
J Cell Physiol
, vol.213
, pp. 649-653
-
-
Alam, N.1
Goel, H.L.2
Zarif, M.J.3
Butterfield, J.E.4
Perkins, H.M.5
Sansoucy, B.G.6
-
4
-
-
62149091091
-
Signal co-operation between integrins and other receptor systems
-
Streuli CH, Akhtar N. Signal co-operation between integrins and other receptor systems. Biochem J 2009;418:491-506.
-
(2009)
Biochem J
, vol.418
, pp. 491-506
-
-
Streuli, C.H.1
Akhtar, N.2
-
5
-
-
77953513171
-
Crosstalk between integrin and receptor tyrosine kinase signaling in breast carcinoma progression
-
Soung YH, Clifford JL, Chung J. Crosstalk between integrin and receptor tyrosine kinase signaling in breast carcinoma progression. BMB Rep 2010;43:311-8.
-
(2010)
BMB Rep
, vol.43
, pp. 311-318
-
-
Soung, Y.H.1
Clifford, J.L.2
Chung, J.3
-
6
-
-
33746764457
-
Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis
-
Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, et al. Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis. Cell 2006;126:489-502.
-
(2006)
Cell
, vol.126
, pp. 489-502
-
-
Guo, W.1
Pylayeva, Y.2
Pepe, A.3
Yoshioka, T.4
Muller, W.J.5
Inghirami, G.6
-
7
-
-
77957283664
-
Beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression
-
Huck L, Pontier SM, Zuo DM, Muller WJ. Beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression. Proc Natl Acad Sci U S A 2010;107:15559-64.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15559-15564
-
-
Huck, L.1
Pontier, S.M.2
Zuo, D.M.3
Muller, W.J.4
-
8
-
-
0035913186
-
Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer
-
Scherl-Mostageer M, Sommergruber W, Abseher R, Hauptmann R, Ambros P, Schweifer N. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene 2001;20:4402-8.
-
(2001)
Oncogene
, vol.20
, pp. 4402-4408
-
-
Scherl-Mostageer, M.1
Sommergruber, W.2
Abseher, R.3
Hauptmann, R.4
Ambros, P.5
Schweifer, N.6
-
9
-
-
24044548332
-
Adhesion signaling by a novel mitotic substrate of src kinases
-
Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM. Adhesion signaling by a novel mitotic substrate of src kinases. Oncogene 2005;24:5333-43.
-
(2005)
Oncogene
, vol.24
, pp. 5333-5343
-
-
Bhatt, A.S.1
Erdjument-Bromage, H.2
Tempst, P.3
Craik, C.S.4
Moasser, M.M.5
-
10
-
-
0037468568
-
Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen
-
Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D, et al. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 2003;22:1783-94.
-
(2003)
Oncogene
, vol.22
, pp. 1783-1794
-
-
Hooper, J.D.1
Zijlstra, A.2
Aimes, R.T.3
Liang, H.4
Claassen, G.F.5
Tarin, D.6
-
11
-
-
2442446451
-
Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia
-
Brown TA, Yang TM, Zaitsevskaia T, Xia Y, Dunn CA, Sigle RO, et al. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. J Biol Chem 2004;279:14772-83.
-
(2004)
J Biol Chem
, vol.279
, pp. 14772-14783
-
-
Brown, T.A.1
Yang, T.M.2
Zaitsevskaia, T.3
Xia, Y.4
Dunn, C.A.5
Sigle, R.O.6
-
12
-
-
77956210264
-
Proteolysis induced amino terminal ectodomain shedding of the integral membrane glycoprotein CUB domain containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its carboxy terminal domain and recruitment of Src and PKC{delta}
-
He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, et al. Proteolysis induced amino terminal ectodomain shedding of the integral membrane glycoprotein CUB domain containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its carboxy terminal domain and recruitment of Src and PKC{delta}. J Biol Chem 2010;285:26162-73.
-
(2010)
J Biol Chem
, vol.285
, pp. 26162-26173
-
-
He, Y.1
Wortmann, A.2
Burke, L.J.3
Reid, J.C.4
Adams, M.N.5
Abdul-Jabbar, I.6
-
13
-
-
65649095219
-
The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation
-
Spassov DS, Baehner FL, Wong CH, McDonough S, Moasser MM. The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation. Am J Pathol 2009;174:1756-65.
-
(2009)
Am J Pathol
, vol.174
, pp. 1756-1765
-
-
Spassov, D.S.1
Baehner, F.L.2
Wong, C.H.3
McDonough, S.4
Moasser, M.M.5
-
14
-
-
0038468563
-
CDCP1 is a novel marker for hematopoietic stem cells
-
Conze T, Lammers R, Kuci S, Scherl-Mostageer M, Schweifer N, Kanz L, et al. CDCP1 is a novel marker for hematopoietic stem cells. AnnN Y Acad Sci 2003;996:222-6.
-
(2003)
AnnN y Acad Sci
, vol.996
, pp. 222-226
-
-
Conze, T.1
Lammers, R.2
Kuci, S.3
Scherl-Mostageer, M.4
Schweifer, N.5
Kanz, L.6
-
15
-
-
79954559586
-
Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state
-
Spassov DS, Wong CH, Moasser MM. Trask phosphorylation defines the reverse mode of a phosphotyrosine signaling switch that underlies cell anchorage state. Cell Cycle 2011;10:1225-32.
-
(2011)
Cell Cycle
, vol.10
, pp. 1225-1232
-
-
Spassov, D.S.1
Wong, C.H.2
Moasser, M.M.3
-
16
-
-
79251547965
-
Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling
-
Spassov DS, Wong CH, Sergina N, Ahuja D, Fried M, Sheppard D, et al. Phosphorylation of Trask by Src kinases inhibits integrin clustering and functions in exclusion with focal adhesion signaling. Mol Cell Biol 2011;31:766-82.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 766-782
-
-
Spassov, D.S.1
Wong, C.H.2
Sergina, N.3
Ahuja, D.4
Fried, M.5
Sheppard, D.6
-
17
-
-
79954545673
-
The structural features of Trask that mediate its anti-adhesive functions
-
Spassov DS, Ahuja D, Wong CH, Moasser MM. The structural features of Trask that mediate its anti-adhesive functions. PLoS ONE 2011;6: e19154.
-
(2011)
PLoS ONE
, vol.6
-
-
Spassov, D.S.1
Ahuja, D.2
Wong, C.H.3
Moasser, M.M.4
-
18
-
-
65249184413
-
Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers
-
Wong CH, Baehner FL, Spassov DS, Ahuja D, Wang D, Hann B, et al. Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers. Clin Cancer Res 2009;15:2311-22.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2311-2322
-
-
Wong, C.H.1
Baehner, F.L.2
Spassov, D.S.3
Ahuja, D.4
Wang, D.5
Hann, B.6
-
19
-
-
84856214036
-
A tumor-suppressing function in the epithelial adhesion protein Trask
-
Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, et al. A tumor-suppressing function in the epithelial adhesion protein Trask. Oncogene. 2012;31:419-31.
-
(2012)
Oncogene.
, vol.31
, pp. 419-431
-
-
Spassov, D.S.1
Wong, C.H.2
Harris, G.3
McDonough, S.4
Phojanakong, P.5
Wang, D.6
-
20
-
-
69949136621
-
Primary cilia can both mediate and suppress Hedgehog pathwaydependent tumorigenesis
-
Wong SY, Seol AD, So P-L, Ermilov AN, Bichakjian CK, Epstein EH, et al. Primary cilia can both mediate and suppress Hedgehog pathwaydependent tumorigenesis. Nat Med 2009;15:1055-61.
-
(2009)
Nat Med
, vol.15
, pp. 1055-1061
-
-
Wong, S.Y.1
Seol, A.D.2
So, P.-L.3
Ermilov, A.N.4
Bichakjian, C.K.5
Epstein, E.H.6
-
21
-
-
34247142787
-
C-Met is essential for wound healing in the skin
-
Chmielowiec J, Borowiak M, Morkel M, Stradal T, Munz B, Werner S, et al. c-Met is essential for wound healing in the skin. J Cell Biol 2007;177:151-62.
-
(2007)
J Cell Biol
, vol.177
, pp. 151-162
-
-
Chmielowiec, J.1
Borowiak, M.2
Morkel, M.3
Stradal, T.4
Munz, B.5
Werner, S.6
-
22
-
-
0030007064
-
Impaired wound healing in mice with a disrupted plasminogen gene
-
Romer J, Bugge TH, Pyke C, Lund LR, Flick MJ, Degen JL, et al. Impaired wound healing in mice with a disrupted plasminogen gene. Nat Med 1996;2:287-92.
-
(1996)
Nat Med
, vol.2
, pp. 287-292
-
-
Romer, J.1
Bugge, T.H.2
Pyke, C.3
Lund, L.R.4
Flick, M.J.5
Degen, J.L.6
-
23
-
-
0037603113
-
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
-
Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003;30:256-68.
-
(2003)
Methods
, vol.30
, pp. 256-268
-
-
Debnath, J.1
Muthuswamy, S.K.2
Brugge, J.S.3
-
24
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
-
Guy CT, Cardiff RD, Muller WJ. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 1992;12:954-61.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
25
-
-
2542481699
-
The integrin beta1 subunit transmembrane domain regulates phosphatidylinositol 3-kinase-dependent tyrosine phosphorylation of Crk-associated substrate
-
Armulik A, Velling T, Johansson S. The integrin beta1 subunit transmembrane domain regulates phosphatidylinositol 3-kinase-dependent tyrosine phosphorylation of Crk-associated substrate. Mol Biol Cell 2004;15:2558-67.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2558-2567
-
-
Armulik, A.1
Velling, T.2
Johansson, S.3
-
26
-
-
2642683511
-
Mutational analysis of the potential phosphorylation sites in the cytoplasmic domain of integrin beta1A. Requirement for threonines 788-789 in receptor activation
-
Wennerberg K, Fassler R, Warmegard B, Johansson S. Mutational analysis of the potential phosphorylation sites in the cytoplasmic domain of integrin beta1A. Requirement for threonines 788-789 in receptor activation. J Cell Sci 1998;111 (Pt 8):1117-26.
-
(1998)
J Cell Sci
, vol.111
, Issue.PART. 8
, pp. 1117-1126
-
-
Wennerberg, K.1
Fassler, R.2
Warmegard, B.3
Johansson, S.4
-
27
-
-
38049098089
-
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
-
Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, et al. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci U S A 2007;104:20302-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20302-20307
-
-
Lahlou, H.1
Sanguin-Gendreau, V.2
Zuo, D.3
Cardiff, R.D.4
McLean, G.W.5
Frame, M.C.6
-
28
-
-
61749094852
-
Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling
-
Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. J Clin Invest 2009;119:252-66.
-
(2009)
J Clin Invest
, vol.119
, pp. 252-266
-
-
Pylayeva, Y.1
Gillen, K.M.2
Gerald, W.3
Beggs, H.E.4
Reichardt, L.F.5
Giancotti, F.G.6
-
29
-
-
45549086918
-
Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model
-
Siva AC, Wild MA, Kirkland RE, Nolan MJ, Lin B, Maruyama T, et al. Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model. Cancer Res 2008;68:3759-66.
-
(2008)
Cancer Res
, vol.68
, pp. 3759-3766
-
-
Siva, A.C.1
Wild, M.A.2
Kirkland, R.E.3
Nolan, M.J.4
Lin, B.5
Maruyama, T.6
-
30
-
-
85047688435
-
3p21. 3 tumor suppressor cluster: Prospects for translational applications
-
Ji L, Minna JD, Roth JA. 3p21.3 tumor suppressor cluster: prospects for translational applications. Future Oncol 2005;1:79-92.
-
(2005)
Future Oncol
, vol.1
, pp. 79-92
-
-
Ji, L.1
Minna, J.D.2
Roth, J.A.3
-
31
-
-
19244370711
-
High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
-
Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 2000;60:1949-60.
-
(2000)
Cancer Res
, vol.60
, pp. 1949-1960
-
-
Wistuba, I.I.1
Behrens, C.2
Virmani, A.K.3
Mele, G.4
Milchgrub, S.5
Girard, L.6
-
32
-
-
33747886870
-
Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells
-
Ikeda JI, Morii E, Kimura H, Tomita Y, Takakuwa T, Hasegawa JI, et al. Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells. J Pathol 2006;210:75-84.
-
(2006)
J Pathol
, vol.210
, pp. 75-84
-
-
Ikeda, J.I.1
Morii, E.2
Kimura, H.3
Tomita, Y.4
Takakuwa, T.5
Hasegawa, J.I.6
-
33
-
-
29244462291
-
Characterization of integrin and anchorage dependence in mammary epithelial cells following c-erbB2-induced epithelial-mesenchymal transition
-
Jenndahl LE, Taylor-Papadimitriou J, Baeckstrom D. Characterization of integrin and anchorage dependence in mammary epithelial cells following c-erbB2-induced epithelial-mesenchymal transition. Tumour Biol 2006;27:50-8.
-
(2006)
Tumour Biol
, vol.27
, pp. 50-58
-
-
Jenndahl, L.E.1
Taylor-Papadimitriou, J.2
Baeckstrom, D.3
-
34
-
-
0033000286
-
Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway
-
Aplin AE, Juliano RL. Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway. J Cell Sci 1999;112 (Pt 5):695-706.
-
(1999)
J Cell Sci
, vol.112
, Issue.PART. 5
, pp. 695-706
-
-
Aplin, A.E.1
Juliano, R.L.2
-
35
-
-
0030453194
-
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
-
Miyamoto S, Teramoto H, Gutkind JS, Yamada KM. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J Cell Biol 1996;135:1633-42.
-
(1996)
J Cell Biol
, vol.135
, pp. 1633-1642
-
-
Miyamoto, S.1
Teramoto, H.2
Gutkind, J.S.3
Yamada, K.M.4
-
36
-
-
80053320001
-
[Beta]1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells
-
Morello V, Cabodi S, Sigismund S, Camacho-Leal MP, Repetto D, Volante M, et al. [beta]1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. Oncogene 2011;30: 4087-96.
-
(2011)
Oncogene
, vol.30
, pp. 4087-4096
-
-
Morello, V.1
Cabodi, S.2
Sigismund, S.3
Camacho-Leal, M.P.4
Repetto, D.5
Volante, M.6
-
37
-
-
0037088647
-
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines
-
Moro L, Dolce L, Cabodi S, Bergatto E, Boeri Erba E, Smeriglio M, et al. Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. J Biol Chem 2002;277:9405-14.
-
(2002)
J Biol Chem
, vol.277
, pp. 9405-9414
-
-
Moro, L.1
Dolce, L.2
Cabodi, S.3
Bergatto, E.4
Boeri Erba, E.5
Smeriglio, M.6
-
38
-
-
0031563765
-
Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines
-
Falcioni R, Antonini A, Nistico P, Di Stefano S, Crescenzi M, Natali PG, et al. Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines. Exp Cell Res 1997;236:76-85.
-
(1997)
Exp Cell Res
, vol.236
, pp. 76-85
-
-
Falcioni, R.1
Antonini, A.2
Nistico, P.3
Di Stefano, S.4
Crescenzi, M.5
Natali, P.G.6
-
39
-
-
0033229747
-
Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
-
Renshaw MW, Price LS, Schwartz MA. Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase. J Cell Biol 1999;147:611-8.
-
(1999)
J Cell Biol
, vol.147
, pp. 611-618
-
-
Renshaw, M.W.1
Price, L.S.2
Schwartz, M.A.3
-
40
-
-
0029739950
-
Control of adhesiondependent cell survival by focal adhesion kinase
-
Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY. Control of adhesiondependent cell survival by focal adhesion kinase. J Cell Biol 1996;134:793-9.
-
(1996)
J Cell Biol
, vol.134
, pp. 793-799
-
-
Frisch, S.M.1
Vuori, K.2
Ruoslahti, E.3
Chan-Hui, P.Y.4
|