The transmembrane src substrate trask is an epithelial protein that signals during anchorage deprivation

American Journal of Pathology

Volumn 174, Issue 5, 2009, Pages 1756-1765

  Spassov, Danislav S ^a   Baehner, Frederick L ^a   Ching, Hang Wong ^a   McDonough, Stephen ^a   Moasser, Mark M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PROTEIN TRASK; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; CDCP1 PROTEIN, HUMAN; CELL ADHESION MOLECULE; LEUKOCYTE ANTIGEN; PROTEIN KINASE P60; TUMOR PROTEIN;

ARTICLE; CELL ANCHORAGE; CELL MIGRATION; CONTROLLED STUDY; ENZYME SUBSTRATE; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTERPHASE; MITOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; BREAST; BREAST TUMOR; CELL ADHESION; CELL MOTION; CYTOLOGY; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOBLOTTING; MESODERM; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANTIGENS, CD; BREAST; BREAST NEOPLASMS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; EPITHELIAL CELLS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; INTERPHASE; MESODERM; MITOSIS; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS PP60(C-SRC); SIGNAL TRANSDUCTION;

EID: 65649095219     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.080890     Document Type: Article

References (20)

1. Lee JM, Dedhar S, Kalluri R, Thompson EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006, 172:973-981
2. Courtneidge SA, Fumagalli S: A mitotic function for Src? Trends in Cell Biol 1994, 4:345-347
3. Taylor SJ, Shalloway D: Src and the control of cell division. [Review] [40 refs]. Bioessays 1996, 18:9-11 (Pubitemid 3022052)
4. Chackalaparampil I, Shalloway D: Altered phosphorylation and activation of pp60c-src during fibroblast mitosis. Cell 1988, 52:801-810
5. Park J, Cartwright CA: Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells. Mol Cell Biol 1995, 15:2374-2382
6. Morgan DO, Kaplan JM, Bishop JM, Varmus HE: Mitosis-specific phosphorylation of p60 c-src by p34 cdc2-associated protein kinase. Cell 1989, 57:775-786 (Pubitemid 19149817)
7. David-Pfeuty T, Nouvian-Dooghe Y: Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells. J Cell Biol 1990, 111:3097-3116 (Pubitemid 120034046)
8. Bagrodia S, laudano AP, Shalloway D: Accessibility of the c-src SH2 domain for binding is increased during mitosis. J Biol Chem 1994, 269:10247-10251
9. Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM: Adhesion signaling by a novel mitotic substrate of src kinases. Oncogene 2005, 24:5333-5343 (Pubitemid 43080103)
10. Scherl-Mostageer M, Sommergruber W, Abseher R, Hauptmann R, Ambros P, Schweifer N: Identification of a novel gene. CDCP1, overexpressed in human colorectal cancer. Oncogene 2001, 20:4402-4408
11. Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D, Testa JE, Quigley JP: Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 2003, 22:1783-1794 (Pubitemid 36513138)
12. Andre M, Le Caer JP, Greco C, Planchon S, El Nemer W, Boucheix C, Rubinstein E, Chamot-Rooke J, Le Naour F: Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS. Proteomics 2006, 6:1437-1449 (Pubitemid 43792794)
13. Conze T, Lammers R, Kuci S, Scherl-Mostageer M, Schweifer N, Kanz L, Buhring HJ: CDCP1 is a novel marker for hematopoietic stem cells. Ann NY Acad Sci 2003, 996:222-226 (Pubitemid 36706603)
14. Wei L, Yang Y, Zhang X, Yu Q: Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene 2004, 23:9052-9061 (Pubitemid 40013072)
15. Loza-Coll MA, Perera S, Shi W, Filmus J: A transient increase in the activity of Src-family kinases induced by cell detachment delays anoikis of intestinal epithelial cells. Oncogene 2005, 24:1727-1737 (Pubitemid 40461129)
16. Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE: Src activation regulates anoikis in human colon tumor cell lines. Oncogene 2002, 21:7797-7807 (Pubitemid 35398837)
17. Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R: CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol Cell Biol 2007, 27:7649-7660 (Pubitemid 350033670)
18. Perry SE, Robinson P, Melcher A, Quirke P, Buhring HJ, Cook GP, Blair GE: Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells. FEBS Lett 2007, 581:1137-1142 (Pubitemid 46385936)
19. Uekita T, Tanaka M, Takigahira M, Miyazawa Y, Nakanishi Y, Kanai Y, Yanagihara K, Sakai R: CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am J Pathol 2008, 172:1729-1739
20. Siva AC, Wild MA, Kirkland RE, Nolan MJ, Lin B, Maruyama T, Yantiri-Wernimont F, Frederickson S, Bowdish KS, Xin H: Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model. Cancer Res 2008, 68:3759-3766