-
1
-
-
0345687176
-
Src kinase activation by direct interaction with the integrin beta cytoplasmic domain
-
Arias-Salgado, E. G., et al. 2003. Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. Proc. Natl. Acad. Sci. U. S. A. 100:13298-13302.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13298-13302
-
-
Arias-Salgado, E.G.1
-
2
-
-
28444497446
-
Integrin structure, allostery, and bidirectional signaling
-
Arnaout, M. A., B. Mahalingam, and J. P. Xiong. 2005. Integrin structure, allostery, and bidirectional signaling. Annu. Rev. Cell Dev. Biol. 21:381-410.
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 381-410
-
-
Arnaout, M.A.1
Mahalingam, B.2
Xiong, J.P.3
-
3
-
-
54949158631
-
Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma
-
Awakura, Y., et al. 2008. Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma. J. Cancer Res. Clin. Oncol. 134:1363-1369.
-
(2008)
J. Cancer Res. Clin. Oncol.
, vol.134
, pp. 1363-1369
-
-
Awakura, Y.1
-
4
-
-
0029166094
-
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase
-
Bellis, S. L., J. T. Miller, and C. E. Turner. 1995. Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J. Biol. Chem. 270:17437-17441.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17437-17441
-
-
Bellis, S.L.1
Miller, J.T.2
Turner, C.E.3
-
5
-
-
24044548332
-
Adhesion signaling by a novel mitotic substrate of src kinases
-
Bhatt, A. S., H. Erdjument-Bromage, P. Tempst, C. S. Craik, and M. M. Moasser. 2005. Adhesion signaling by a novel mitotic substrate of src kinases. Oncogene 24:5333-5343.
-
(2005)
Oncogene
, vol.24
, pp. 5333-5343
-
-
Bhatt, A.S.1
Erdjument-Bromage, H.2
Tempst, P.3
Craik, C.S.4
Moasser, M.M.5
-
6
-
-
0036384346
-
Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cells
-
Blaschke, F., et al. 2002. Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 296:890-896.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 890-896
-
-
Blaschke, F.1
-
7
-
-
0029146869
-
An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn-, and yes- Mice
-
Bockholt, S. M., and K. Burridge. 1995. An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn-, and yes- mice. Cell Adhes. Commun. 3:91-100.
-
(1995)
Cell Adhes. Commun.
, vol.3
, pp. 91-100
-
-
Bockholt, S.M.1
Burridge, K.2
-
8
-
-
2442446451
-
Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia
-
Brown, T. A., et al. 2004. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. J. Biol. Chem. 279:14772-14783.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14772-14783
-
-
Brown, T.A.1
-
9
-
-
0037077282
-
The phosphotyrosine binding-like domain of talin activates integrins
-
Calderwood, D. A., et al. 2002. The phosphotyrosine binding-like domain of talin activates integrins. J. Biol. Chem. 277:21749-21758.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21749-21758
-
-
Calderwood, D.A.1
-
10
-
-
3042717667
-
Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
-
Chodniewicz, D., and R. L. Klemke. 2004. Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold. Biochim. Biophys. Acta 1692:63-76.
-
(2004)
Biochim. Biophys. Acta
, vol.1692
, pp. 63-76
-
-
Chodniewicz, D.1
Klemke, R.L.2
-
11
-
-
0019294081
-
Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus
-
David-Pfeuty, T., and S. J. Singer. 1980. Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus. Proc. Natl. Acad. Sci. U. S. A. 77:6687-6691.
-
(1980)
Proc. Natl. Acad. Sci. U. S. A.
, vol.77
, pp. 6687-6691
-
-
David-Pfeuty, T.1
Singer, S.J.2
-
12
-
-
69449097220
-
Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination
-
Deryugina, E. I., et al. 2009. Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Mol. Cancer Res. 7:1197-1211.
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1197-1211
-
-
Deryugina, E.I.1
-
13
-
-
0027215041
-
Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1)
-
Dittel, B. N., J. B. McCarthy, E. A. Wayner, and T. W. LeBien. 1993. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1). Blood 81:2272-2282.
-
(1993)
Blood
, vol.81
, pp. 2272-2282
-
-
Dittel, B.N.1
McCarthy, J.B.2
Wayner, E.A.3
LeBien, T.W.4
-
14
-
-
53049096953
-
Structure and dynamic regulation of Src-family kinases
-
Engen, J. R., et al. 2008. Structure and dynamic regulation of Src-family kinases. Cell. Mol. Life Sci. 65:3058-3073.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3058-3073
-
-
Engen, J.R.1
-
15
-
-
0032472411
-
The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
-
Fincham, V. J., and M. C. Frame. 1998. The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J. 17:81-92.
-
(1998)
EMBO J.
, vol.17
, pp. 81-92
-
-
Fincham, V.J.1
Frame, M.C.2
-
16
-
-
0030482560
-
Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins
-
Fincham, V. J., et al. 1996. Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins. J. Cell Biol. 135:1551-1564.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1551-1564
-
-
Fincham, V.J.1
-
17
-
-
1842584776
-
Newest findings on the oldest oncogene; how activated src does it
-
Frame, M. C. 2004. Newest findings on the oldest oncogene; how activated src does it. J. Cell Sci. 117:989-998.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 989-998
-
-
Frame, M.C.1
-
18
-
-
0036270145
-
v-Src's hold over actin and cell adhesions
-
Frame, M. C., V. J. Fincham, N. O. Carragher, and J. A. Wyke. 2002. v-Src's hold over actin and cell adhesions. Nat. Rev. Mol. Cell Biol. 3:233-245.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 233-245
-
-
Frame, M.C.1
Fincham, V.J.2
Carragher, N.O.3
Wyke, J.A.4
-
19
-
-
76249092590
-
Inhibition of tumor metastasis: Functional immune modulation of the CUB domain containing protein 1
-
Fukuchi, K., et al. 2010. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Mol. Pharm. 7:245-253.
-
(2010)
Mol. Pharm.
, vol.7
, pp. 245-253
-
-
Fukuchi, K.1
-
20
-
-
0024382542
-
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton
-
Glenney, J. R., Jr., and L. Zokas. 1989. Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton. J. Cell Biol. 108:2401-2408.
-
(1989)
J. Cell Biol.
, vol.108
, pp. 2401-2408
-
-
Glenney Jr., J.R.1
Zokas, L.2
-
21
-
-
0029666251
-
p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase
-
Harte, M. T., J. D. Hildebrand, M. R. Burnham, A. H. Bouton, and J. T. Parsons. 1996. p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase. J. Biol. Chem. 271:13649-13655.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13649-13655
-
-
Harte, M.T.1
Hildebrand, J.D.2
Burnham, M.R.3
Bouton, A.H.4
Parsons, J.T.5
-
22
-
-
0037468568
-
Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen
-
Hooper, J. D., et al. 2003. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene 22:1783-1794.
-
(2003)
Oncogene
, vol.22
, pp. 1783-1794
-
-
Hooper, J.D.1
-
23
-
-
66849101632
-
Adhesion signaling - Crosstalk between integrins, Src and Rho
-
Huveneers, S., and E. H. Danen. 2009. Adhesion signaling - crosstalk between integrins, Src and Rho. J. Cell Sci. 122:1059-1069.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1059-1069
-
-
Huveneers, S.1
Danen, E.H.2
-
24
-
-
62849106338
-
Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung
-
Ikeda, J., et al. 2009. Expression of CUB domain containing protein (CDCP1) is correlated with prognosis and survival of patients with adenocarcinoma of lung. Cancer Sci. 100:429-433.
-
(2009)
Cancer Sci.
, vol.100
, pp. 429-433
-
-
Ikeda, J.1
-
25
-
-
0028151515
-
Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527
-
Kaplan, K. B., et al. 1994. Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J. 13:4745-4756.
-
(1994)
EMBO J.
, vol.13
, pp. 4745-4756
-
-
Kaplan, K.B.1
-
26
-
-
0029034939
-
c-Src enhances the spreading of src-/- Fibroblasts on fibronectin by a kinase-independent mechanism
-
Kaplan, K. B., J. R. Swedlow, D. O. Morgan, and H. E. Varmus. 1995. c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism. Genes Dev. 9:1505-1517.
-
(1995)
Genes Dev.
, vol.9
, pp. 1505-1517
-
-
Kaplan, K.B.1
Swedlow, J.R.2
Morgan, D.O.3
Varmus, H.E.4
-
27
-
-
0033522510
-
Src family kinases are required for integrin but not PDGFR signal transduction
-
Klinghoffer, R. A., C. Sachsenmaier, J. A. Cooper, and P. Soriano. 1999. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J. 18:2459-2471.
-
(1999)
EMBO J.
, vol.18
, pp. 2459-2471
-
-
Klinghoffer, R.A.1
Sachsenmaier, C.2
Cooper, J.A.3
Soriano, P.4
-
28
-
-
77950820633
-
Prognostic significance of CUB domain containing protein expression in endometrioid adenocarcinoma
-
Mamat, S., et al. 2010. Prognostic significance of CUB domain containing protein expression in endometrioid adenocarcinoma. Oncol. Rep. 23:1221-1227.
-
(2010)
Oncol. Rep.
, vol.23
, pp. 1221-1227
-
-
Mamat, S.1
-
29
-
-
34249821363
-
Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions
-
McCleverty, C. J., D. C. Lin, and R. C. Liddington. 2007. Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions. Protein Sci. 16:1223-1229.
-
(2007)
Protein Sci.
, vol.16
, pp. 1223-1229
-
-
McCleverty, C.J.1
Lin, D.C.2
Liddington, R.C.3
-
30
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra, S. K., and D. D. Schlaepfer. 2006. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 18:516-523.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
31
-
-
77953797255
-
CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation
-
Miyazawa, Y., et al. 2010. CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation. Cancer Res. 70:5136-5146.
-
(2010)
Cancer Res.
, vol.70
, pp. 5136-5146
-
-
Miyazawa, Y.1
-
32
-
-
66149128873
-
The tail of integrins, talin, and kindlins
-
Moser, M., K. R. Legate, R. Zent, and R. Fassler. 2009. The tail of integrins, talin, and kindlins. Science 324:895-899.
-
(2009)
Science
, vol.324
, pp. 895-899
-
-
Moser, M.1
Legate, K.R.2
Zent, R.3
Fassler, R.4
-
33
-
-
0020189847
-
Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide
-
Nigg, E. A., B. M. Sefton, T. Hunter, G. Walter, and S. J. Singer. 1982. Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proc. Natl. Acad. Sci. U. S. A. 79:5322-5326.
-
(1982)
Proc. Natl. Acad. Sci. U. S. A.
, vol.79
, pp. 5322-5326
-
-
Nigg, E.A.1
Sefton, B.M.2
Hunter, T.3
Walter, G.4
Singer, S.J.5
-
34
-
-
7944236785
-
Src family kinases, key regulators of signal transduction
-
Parsons, S. J., and J. T. Parsons. 2004. Src family kinases, key regulators of signal transduction. Oncogene 23:7906-7909.
-
(2004)
Oncogene
, vol.23
, pp. 7906-7909
-
-
Parsons, S.J.1
Parsons, J.T.2
-
35
-
-
7944233251
-
The interplay between Src and integrins in normal and tumor biology
-
Playford, M. P., and M. D. Schaller. 2004. The interplay between Src and integrins in normal and tumor biology. Oncogene 23:7928-7946.
-
(2004)
Oncogene
, vol.23
, pp. 7928-7946
-
-
Playford, M.P.1
Schaller, M.D.2
-
36
-
-
0035957395
-
Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src
-
Sakai, T., R. Jove, R. Fassler, and D. F. Mosher. 2001. Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src. Proc. Natl. Acad. Sci. U. S. A. 98:3808-3813.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 3808-3813
-
-
Sakai, T.1
Jove, R.2
Fassler, R.3
Mosher, D.F.4
-
37
-
-
0028350859
-
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
-
Schaller, M. D., et al. 1994. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol. Cell. Biol. 14:1680-1688.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1680-1688
-
-
Schaller, M.D.1
-
38
-
-
0028986116
-
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
-
Schaller, M. D., and J. T. Parsons. 1995. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol. 15:2635-2645.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2635-2645
-
-
Schaller, M.D.1
Parsons, J.T.2
-
39
-
-
0035913186
-
Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer
-
Scherl-Mostageer, M., et al. 2001. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene 20:4402-4408.
-
(2001)
Oncogene
, vol.20
, pp. 4402-4408
-
-
Scherl-Mostageer, M.1
-
40
-
-
23744451167
-
Integrins and Src: Dynamic duo of adhesion signaling
-
Shattil, S. J. 2005. Integrins and Src: dynamic duo of adhesion signaling. Trends Cell Biol. 15:399-403.
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 399-403
-
-
Shattil, S.J.1
-
41
-
-
45549086918
-
Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model
-
Siva, A. C., et al. 2008. Targeting CUB domain-containing protein 1 with a monoclonal antibody inhibits metastasis in a prostate cancer model. Cancer Res. 68:3759-3766.
-
(2008)
Cancer Res.
, vol.68
, pp. 3759-3766
-
-
Siva, A.C.1
-
42
-
-
65649095219
-
The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation
-
Spassov, D. S., F. L. Baehner, C. H. Wong, S. McDonough, and M. M. Moasser. 2009. The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation. Am. J. Pathol. 174:1756-1765.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 1756-1765
-
-
Spassov, D.S.1
Baehner, F.L.2
Wong, C.H.3
McDonough, S.4
Moasser, M.M.5
-
43
-
-
0035960717
-
Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity
-
Timpson, P., G. E. Jones, M. C. Frame, and V. G. Brunton. 2001. Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity. Curr. Biol. 11:1836-1846.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1836-1846
-
-
Timpson, P.1
Jones, G.E.2
Frame, M.C.3
Brunton, V.G.4
-
44
-
-
0033666291
-
Paxillin and focal adhesion signalling
-
Turner, C. E. 2000. Paxillin and focal adhesion signalling. Nat. Cell Biol. 2:E231-E236.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Turner, C.E.1
-
45
-
-
35649025769
-
CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma
-
Uekita, T., et al. 2007. CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol. Cell. Biol. 27:7649-7660.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7649-7660
-
-
Uekita, T.1
-
46
-
-
44849141807
-
CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma
-
Uekita, T., et al. 2008. CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am. J. Pathol. 172:1729-1739.
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 1729-1739
-
-
Uekita, T.1
-
47
-
-
0034941053
-
Pp60(c-src) and related tyrosine kinases: A role in the assembly and reorganization of matrix adhesions
-
Volberg, T., L. Romer, E. Zamir, and B. Geiger. 2001. pp60(c-src) and related tyrosine kinases: a role in the assembly and reorganization of matrix adhesions. J. Cell Sci. 114:2279-2289.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2279-2289
-
-
Volberg, T.1
Romer, L.2
Zamir, E.3
Geiger, B.4
-
48
-
-
0031694935
-
Integrin signaling: Tyrosine phosphorylation events in focal adhesions
-
Vuori, K. 1998. Integrin signaling: tyrosine phosphorylation events in focal adhesions. J. Membr. Biol. 165:191-199.
-
(1998)
J. Membr. Biol.
, vol.165
, pp. 191-199
-
-
Vuori, K.1
-
49
-
-
33845987101
-
Structural basis of integrin activation by talin
-
Wegener, K. L., et al. 2007. Structural basis of integrin activation by talin. Cell 128:171-182.
-
(2007)
Cell
, vol.128
, pp. 171-182
-
-
Wegener, K.L.1
-
50
-
-
65249184413
-
Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers
-
Wong, C. H., et al. 2009. Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers. Clin. Cancer Res. 15:2311-2322.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2311-2322
-
-
Wong, C.H.1
-
51
-
-
33748659504
-
The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src
-
Yamana, N., et al. 2006. The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol. Cell. Biol. 26:6844-6858.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6844-6858
-
-
Yamana, N.1
-
52
-
-
0028171068
-
The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin
-
Yokosaki, Y., et al. 1994. The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin. J. Biol. Chem. 269:26691-26696.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26691-26696
-
-
Yokosaki, Y.1
|