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Volumn 751, Issue 1, 2013, Pages 12-18

Development of a repeated-dose liver micronucleus assay using adult rats (II): Further investigation of 1,2-dimethylhydrazine and 2,6-diaminotoluene

Author keywords

Adult rat; Bone marrow micronucleus assay; Hepatocarcinogen; Liver micronucleus assay; Repeated dose toxicity study

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 2,6 DIAMINOTOLUENE;

EID: 84873428968     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.10.004     Document Type: Article
Times cited : (27)

References (38)
  • 1
    • 0029025271 scopus 로고
    • Tissues other than bone marrow that can be used for cytogenetic analysis
    • Angelosanto F.A. Tissues other than bone marrow that can be used for cytogenetic analysis. Environ. Mol. Mutagen. 1995, 25:338-343.
    • (1995) Environ. Mol. Mutagen. , vol.25 , pp. 338-343
    • Angelosanto, F.A.1
  • 2
    • 0024558686 scopus 로고
    • The role of short-lived lesions in the induction of micronuclei in rat liver by ethylnitrosourea and methyl methanesulphonate: the importance of experimental design
    • Tates A.D., Den Engelse L. The role of short-lived lesions in the induction of micronuclei in rat liver by ethylnitrosourea and methyl methanesulphonate: the importance of experimental design. Mutat. Res. 1989, 210:271-279.
    • (1989) Mutat. Res. , vol.210 , pp. 271-279
    • Tates, A.D.1    Den Engelse, L.2
  • 3
    • 0023860450 scopus 로고
    • A non-invasive micronucleus assay in the rat liver
    • Braithwaite I., Ashby J. A non-invasive micronucleus assay in the rat liver. Mutat. Res. 1988, 203:23-32.
    • (1988) Mutat. Res. , vol.203 , pp. 23-32
    • Braithwaite, I.1    Ashby, J.2
  • 4
    • 0024523356 scopus 로고
    • The rat-liver carcinogen N-nitrosomorpholine initiates unscheduled DNA synthesis and induces micronuclei in the rat liver in vivo
    • Ashby J., Lefevre P.A. The rat-liver carcinogen N-nitrosomorpholine initiates unscheduled DNA synthesis and induces micronuclei in the rat liver in vivo. Mutat. Res. 1989, 225:143-147.
    • (1989) Mutat. Res. , vol.225 , pp. 143-147
    • Ashby, J.1    Lefevre, P.A.2
  • 5
    • 20144374698 scopus 로고    scopus 로고
    • Evaluation of liver and peripheral blood micronucleus assays with 9 chemicals using young rats. A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS)
    • Suzuki H., Ikeda N., Kobayashi K., Terashima Y., Shimada Y., Suzuki T., Hagiwara T., Hatakeyama S., Nagaoka K., Yoshida J., Saito Y., Tanaka J., Hayashi M. Evaluation of liver and peripheral blood micronucleus assays with 9 chemicals using young rats. A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). Mutat. Res. 2005, 583:133-145.
    • (2005) Mutat. Res. , vol.583 , pp. 133-145
    • Suzuki, H.1    Ikeda, N.2    Kobayashi, K.3    Terashima, Y.4    Shimada, Y.5    Suzuki, T.6    Hagiwara, T.7    Hatakeyama, S.8    Nagaoka, K.9    Yoshida, J.10    Saito, Y.11    Tanaka, J.12    Hayashi, M.13
  • 6
    • 58149126271 scopus 로고    scopus 로고
    • Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group
    • Suzuki H., Takasawa H., Kobayashi K., Terashima Y., Shimada Y., Ogawa I., Tanaka J., Imamura T., Miyazaki A., Hayashi M. Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group. Mutagenesis 2009, 24:9-16.
    • (2009) Mutagenesis , vol.24 , pp. 9-16
    • Suzuki, H.1    Takasawa, H.2    Kobayashi, K.3    Terashima, Y.4    Shimada, Y.5    Ogawa, I.6    Tanaka, J.7    Imamura, T.8    Miyazaki, A.9    Hayashi, M.10
  • 7
    • 77954902380 scopus 로고    scopus 로고
    • Evaluation of a liver micronucleus assay in young rats (III): a study using nine hepatotoxicants by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS)
    • Takasawa H., Suzuki H., Ogawa I., Shimada Y., Kobayashi K., Terashima Y., Matsumoto H., Aruga C., Oshida K., Ohta R., Imamura T., Miyazaki A., Kawabata M., Minowa S., Hayashi M. Evaluation of a liver micronucleus assay in young rats (III): a study using nine hepatotoxicants by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). Mutat. Res. 2010, 698:30-37.
    • (2010) Mutat. Res. , vol.698 , pp. 30-37
    • Takasawa, H.1    Suzuki, H.2    Ogawa, I.3    Shimada, Y.4    Kobayashi, K.5    Terashima, Y.6    Matsumoto, H.7    Aruga, C.8    Oshida, K.9    Ohta, R.10    Imamura, T.11    Miyazaki, A.12    Kawabata, M.13    Minowa, S.14    Hayashi, M.15
  • 8
    • 77954893923 scopus 로고    scopus 로고
    • Evaluation of a liver micronucleus assay in young rats (IV): a study using a double-dosing/single-sampling method by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS)
    • Takasawa H., Suzuki H., Ogawa I., Shimada Y., Kobayashi K., Terashima Y., Matsumoto H., Oshida K., Ohta R., Imamura T., Miyazaki A., Kawabata M., Minowa S., Maeda A., Hayashi M. Evaluation of a liver micronucleus assay in young rats (IV): a study using a double-dosing/single-sampling method by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). Mutat. Res. 2010, 698:24-29.
    • (2010) Mutat. Res. , vol.698 , pp. 24-29
    • Takasawa, H.1    Suzuki, H.2    Ogawa, I.3    Shimada, Y.4    Kobayashi, K.5    Terashima, Y.6    Matsumoto, H.7    Oshida, K.8    Ohta, R.9    Imamura, T.10    Miyazaki, A.11    Kawabata, M.12    Minowa, S.13    Maeda, A.14    Hayashi, M.15
  • 9
    • 0030871409 scopus 로고    scopus 로고
    • Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Group 1, 2A and 2B). The summary report of the 6th collaborative study by CSGMT/JEMS MMS
    • Morita T., Asano N., Awogi T., Sasaki Y., Sato S., Shimada H., Sutou S., Suzuki T., Wakata A., Sofuni T., Hayashi M. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Group 1, 2A and 2B). The summary report of the 6th collaborative study by CSGMT/JEMS MMS. Mutat. Res. 1997, 389:3-122.
    • (1997) Mutat. Res. , vol.389 , pp. 3-122
    • Morita, T.1    Asano, N.2    Awogi, T.3    Sasaki, Y.4    Sato, S.5    Shimada, H.6    Sutou, S.7    Suzuki, T.8    Wakata, A.9    Sofuni, T.10    Hayashi, M.11
  • 11
    • 0024332230 scopus 로고
    • In vivo micronucleus test using mouse hepatocytes
    • Cliet I., Fournier E., Melcion C., Cordier A. In vivo micronucleus test using mouse hepatocytes. Mutat. Res. 1989, 216:321-326.
    • (1989) Mutat. Res. , vol.216 , pp. 321-326
    • Cliet, I.1    Fournier, E.2    Melcion, C.3    Cordier, A.4
  • 12
    • 0030580937 scopus 로고    scopus 로고
    • Selective induction of micronuclei in the rat/mouse colon and liver by 1,2-dimethylhydrazine: a seven-tissue comparative study
    • Zhurkov V.S., Sycheva L.P., Salamatova O., Vyskubenko I.F., Feldt E.G., Sherenesheva N.I. Selective induction of micronuclei in the rat/mouse colon and liver by 1,2-dimethylhydrazine: a seven-tissue comparative study. Mutat. Res. 1996, 368:115-120.
    • (1996) Mutat. Res. , vol.368 , pp. 115-120
    • Zhurkov, V.S.1    Sycheva, L.P.2    Salamatova, O.3    Vyskubenko, I.F.4    Feldt, E.G.5    Sherenesheva, N.I.6
  • 14
    • 84873423279 scopus 로고    scopus 로고
    • International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Harmonized Tripartite Guideline, Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceutical Intended for Human Use, S2 (R1), Current Step 4 version, dated 9 November
    • International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Harmonized Tripartite Guideline, Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceutical Intended for Human Use, S2 (R1), Current Step 4 version, dated 9 November 2011.
    • (2011)
  • 17
    • 0029024104 scopus 로고
    • Genotoxic and non-genotoxic activities of 2,4- and 2,6-diaminotoluene, as evaluated in Fisher-344 rat liver
    • Taningher M., Peluso M., Parodi S., Ledda-Columbano G.M., Columbano A. Genotoxic and non-genotoxic activities of 2,4- and 2,6-diaminotoluene, as evaluated in Fisher-344 rat liver. Toxicology 1995, 99:1-10.
    • (1995) Toxicology , vol.99 , pp. 1-10
    • Taningher, M.1    Peluso, M.2    Parodi, S.3    Ledda-Columbano, G.M.4    Columbano, A.5
  • 18
    • 0028036087 scopus 로고
    • An in vivo-in vitro replicative DNA synthesis (RDS) test using rat hepatocytes as an early prediction assay for nongenotoxic hepatocarcinogens screening of 22 known positives and 25 noncarcinogens
    • Uno Y., Takasawa H., Miyagawa M., Inoue Y., Murata T., Yoshikawa K. An in vivo-in vitro replicative DNA synthesis (RDS) test using rat hepatocytes as an early prediction assay for nongenotoxic hepatocarcinogens screening of 22 known positives and 25 noncarcinogens. Mutat. Res. 1994, 320:189-205.
    • (1994) Mutat. Res. , vol.320 , pp. 189-205
    • Uno, Y.1    Takasawa, H.2    Miyagawa, M.3    Inoue, Y.4    Murata, T.5    Yoshikawa, K.6
  • 20
    • 0014788551 scopus 로고
    • Tables for determining the statistical significance of mutation frequencies
    • Kastenbaum M.A., Bowman K.O. Tables for determining the statistical significance of mutation frequencies. Mutat. Res. 1970, 9:527-549.
    • (1970) Mutat. Res. , vol.9 , pp. 527-549
    • Kastenbaum, M.A.1    Bowman, K.O.2
  • 21
    • 0031904574 scopus 로고    scopus 로고
    • Evaluation of the rat micronucleus test with bone marrow and peripheral blood: summary of the 9th collaborative study by CSGMT/JEMS MMS
    • Wakata A., Miyamae Y., Sato S., Suzuki T., Morita T., Asano N., Awogi T., Kondo K., Hayashi M. Evaluation of the rat micronucleus test with bone marrow and peripheral blood: summary of the 9th collaborative study by CSGMT/JEMS MMS. Environ. Mol. Mutagen. 1998, 32:84-100.
    • (1998) Environ. Mol. Mutagen. , vol.32 , pp. 84-100
    • Wakata, A.1    Miyamae, Y.2    Sato, S.3    Suzuki, T.4    Morita, T.5    Asano, N.6    Awogi, T.7    Kondo, K.8    Hayashi, M.9
  • 22
    • 0025930779 scopus 로고
    • Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene and 2,4-diaminotoluene using the rat micronucleus test and rat liver UDS assay
    • George E., Westmoreland C. Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene and 2,4-diaminotoluene using the rat micronucleus test and rat liver UDS assay. Carcinogenesis 1991, 12:2233-2237.
    • (1991) Carcinogenesis , vol.12 , pp. 2233-2237
    • George, E.1    Westmoreland, C.2
  • 23
    • 84873426848 scopus 로고
    • IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans
    • IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Supplement 7, International Agency for Research on Cancer, 1987, pp. 947-989.
    • (1987) International Agency for Research on Cancer , Issue.SUPPLEMENT 7 , pp. 947-989
  • 24
    • 0004078420 scopus 로고
    • Bioassay of 2,4-diaminotoluene for possible carcinogenicity
    • NTP
    • NTP Bioassay of 2,4-diaminotoluene for possible carcinogenicity. Natl. Cancer Inst. Carcinog. Tech. Rep. Ser. 1979, 162:1-139.
    • (1979) Natl. Cancer Inst. Carcinog. Tech. Rep. Ser. , vol.162 , pp. 1-139
  • 25
    • 84873457526 scopus 로고    scopus 로고
    • IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide
    • IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans, Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide, International Agency for Research on Cancer, vol. 71, 1999, 947 pp.
    • (1999) International Agency for Research on Cancer , vol.71 , pp. 947
  • 26
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
    • Mirsalis J.C., Tyson C.K., Butterworth B.E. Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ. Mutagen. 1982, 4:553-562.
    • (1982) Environ. Mutagen. , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, C.K.2    Butterworth, B.E.3
  • 27
    • 77951557168 scopus 로고    scopus 로고
    • Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diminotoluene and 2,6-diaminotoluene structural isomers
    • Toyoda-Hokaiwada N., Inoue T., Masumura K., Hayashi H., Kawamura Y., Kurata Y., Takamune M., Yamada M., Sanada H., Umemura T., Nishikawa A., Nohmi T. Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diminotoluene and 2,6-diaminotoluene structural isomers. Toxicol. Sci. 2010, 114:71-78.
    • (2010) Toxicol. Sci. , vol.114 , pp. 71-78
    • Toyoda-Hokaiwada, N.1    Inoue, T.2    Masumura, K.3    Hayashi, H.4    Kawamura, Y.5    Kurata, Y.6    Takamune, M.7    Yamada, M.8    Sanada, H.9    Umemura, T.10    Nishikawa, A.11    Nohmi, T.12
  • 28
    • 0000973407 scopus 로고
    • Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
    • Ashby J., Tennant R.W. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutat. Res. 1991, 257:229-306.
    • (1991) Mutat. Res. , vol.257 , pp. 229-306
    • Ashby, J.1    Tennant, R.W.2
  • 29
    • 0842307733 scopus 로고
    • NTP Bioassay of 2,6-diaminotoluene dihydrochloride for possible carcinogenicity (CAS No. 15481-70-6)
    • NTP Bioassay of 2,6-diaminotoluene dihydrochloride for possible carcinogenicity (CAS No. 15481-70-6). Natl. Toxicol. Program Tech. Rep. Ser. 1980, 200:1-123.
    • (1980) Natl. Toxicol. Program Tech. Rep. Ser. , vol.200 , pp. 1-123
  • 31
    • 33747781714 scopus 로고    scopus 로고
    • Induction of LacZ mutations in Muta™Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes
    • Kirkland D., Beevers C. Induction of LacZ mutations in Muta™Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes. Mutat. Res. 2006, 608:88-96.
    • (2006) Mutat. Res. , vol.608 , pp. 88-96
    • Kirkland, D.1    Beevers, C.2
  • 32
    • 0037213389 scopus 로고    scopus 로고
    • The role of hepatocytes and oval cells in liver regeneration and replication
    • Fausto N., Campbell J.S. The role of hepatocytes and oval cells in liver regeneration and replication. Mech. Dev. 2003, 120:117-130.
    • (2003) Mech. Dev. , vol.120 , pp. 117-130
    • Fausto, N.1    Campbell, J.S.2
  • 34
    • 0344862102 scopus 로고    scopus 로고
    • Evaluation of cell proliferation in rat tissues with BrdU, PCNA, Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA
    • Muskhelishvili L., Latendresse J.R., Kodell R.L., Henderson E.B. Evaluation of cell proliferation in rat tissues with BrdU, PCNA, Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA. J. Histochem. Cytochem. 2003, 51:1681-1688.
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 1681-1688
    • Muskhelishvili, L.1    Latendresse, J.R.2    Kodell, R.L.3    Henderson, E.B.4
  • 35
    • 0033868221 scopus 로고    scopus 로고
    • The nongenotoxic hepatocarcinogens diethylhexylphthalate and methylclofenapate induce DNA synthesis preferentially in octoploid rat hepatocytes
    • Hasmall S.C., Roberts R.A. The nongenotoxic hepatocarcinogens diethylhexylphthalate and methylclofenapate induce DNA synthesis preferentially in octoploid rat hepatocytes. Toxicol. Pathol. 2000, 28:503-509.
    • (2000) Toxicol. Pathol. , vol.28 , pp. 503-509
    • Hasmall, S.C.1    Roberts, R.A.2
  • 36
    • 34447097135 scopus 로고    scopus 로고
    • Optimum conditions for detecting hepatic micronuclei caused by numerical chromosome aberration inducers in mice
    • Igarashi M., Setoguchi M., Takada S., Itoh S., Furuhama K. Optimum conditions for detecting hepatic micronuclei caused by numerical chromosome aberration inducers in mice. Mutat. Res. 2007, 632:89-98.
    • (2007) Mutat. Res. , vol.632 , pp. 89-98
    • Igarashi, M.1    Setoguchi, M.2    Takada, S.3    Itoh, S.4    Furuhama, K.5
  • 37
    • 84862314362 scopus 로고    scopus 로고
    • Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy
    • Itoh S., Hattori C., Nagata M., Sanbuissho A. Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy. Mutat. Res. 2012, 747:98-103.
    • (2012) Mutat. Res. , vol.747 , pp. 98-103
    • Itoh, S.1    Hattori, C.2    Nagata, M.3    Sanbuissho, A.4
  • 38
    • 47849123302 scopus 로고    scopus 로고
    • The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps
    • Holland N., Bolognesi C., Kirsch-Volders M., Bonassi S., Zeiger E., Knasmueller S., Fenech M. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat. Res. 2008, 659:93-108.
    • (2008) Mutat. Res. , vol.659 , pp. 93-108
    • Holland, N.1    Bolognesi, C.2    Kirsch-Volders, M.3    Bonassi, S.4    Zeiger, E.5    Knasmueller, S.6    Fenech, M.7


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