The Nongenotoxic Hepatocarcinogens Diethylhexylphthalate and Methylclofenapate Induce DNA Synthesis Preferentially in Octoploid Rat Hepatocytes

Toxicologic Pathology

Volumn 28, Issue 4, 2000, Pages 503-509

  Hasmall, Susan C ^a   Roberts, Ruth A ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

1,4 dichlorobenzene; diethylhexylphalate; DNA synthesis; ethylene thiourea; hepatocyte ploidy; Methylclofenapate; nongenotoxic hepatocarcinogenesis; phenobarbitone

Indexed keywords

2 IMIDAZOLIDINETHIONE; CARCINOGEN; METHYLCLOFENAPATE; PHENOBARBITAL; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

ANIMAL CELL; ARTICLE; CANCER RISK; CARCINOGENICITY; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA SYNTHESIS; GENE INDUCTION; LIVER CARCINOGENESIS; LIVER CELL; MALE; NONHUMAN; PLOIDY; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICONVULSANTS; ANTIMETABOLITES; BROMODEOXYURIDINE; CARCINOGENS; CELL NUCLEUS; CLOFENAPATE; DIETHYLHEXYL PHTHALATE; DNA; HEPATOCYTES; MALE; PHENYTOIN; POLYPLOIDY; RATS; RATS, INBRED F344;

ANIMALIA; RODENTIA;

EID: 0033868221     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262330002800401     Document Type: Article

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