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Volumn 24, Issue 1, 2009, Pages 9-16

Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): A study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 2,4 DIAMINOTOLUENE; 2,4 DINITROTOLUENE; 4 DIMETHYLAMINOAZOBENZENE; CARCINOGEN; CYCLOPHOSPHAMIDE; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; FLUOROURACIL; MESYLIC ACID ETHYL ESTER; MITOMYCIN C; N (2 FLUORENYL)ACETAMIDE; QUINOLINE;

EID: 58149126271     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gen047     Document Type: Article
Times cited : (63)

References (47)
  • 1
    • 0030871409 scopus 로고    scopus 로고
    • Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B): The summary report of the 6th collaborative study by CSGMT/JEMS· MMS
    • Morita, T., Asano, N., Awogi, T. et al. (1997) Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B): the summary report of the 6th collaborative study by CSGMT/JEMS· MMS. Mutat. Res., 389, 3-122.
    • (1997) Mutat. Res , vol.389 , pp. 3-122
    • Morita, T.1    Asano, N.2    Awogi, T.3
  • 3
    • 58149133092 scopus 로고    scopus 로고
    • Tweats, D. J. (1993) Follow-up testing for in vitro positive. In Obe, P. F. D. and Harron, D. W. G. (eds), Proceedings of the Second International Conference on Harmonisation. The Queen's University of Belfast, Belfast, UK. pp. 240-244.
    • Tweats, D. J. (1993) Follow-up testing for in vitro positive. In Obe, P. F. D. and Harron, D. W. G. (eds), Proceedings of the Second International Conference on Harmonisation. The Queen's University of Belfast, Belfast, UK. pp. 240-244.
  • 4
    • 84906480044 scopus 로고    scopus 로고
    • Consumer Products and the Environment
    • Committee on Mutagenicity of Chemicals in Food, United Kingdom, last accessed May 2008
    • Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (2000) Guidance on a Strategy for Testing of Chemicals for Mutagenicity. United Kingdom. http://www.advisorybodies.doh.gov.uk/com/ guidance.pdf last accessed May 2008.
    • Guidance on a Strategy for Testing of Chemicals for Mutagenicity
  • 5
    • 0032790027 scopus 로고    scopus 로고
    • Study of a rat skin in vivo micronucleus test: Data generated by mitomycin C and methyl methanesulfonate
    • Nishikawa, T., Haresaku, M., Adachi, M., Matsuda, M. and Hayashi, M. (1999) Study of a rat skin in vivo micronucleus test: data generated by mitomycin C and methyl methanesulfonate. Mutat. Res., 444, 159-166.
    • (1999) Mutat. Res , vol.444 , pp. 159-166
    • Nishikawa, T.1    Haresaku, M.2    Adachi, M.3    Matsuda, M.4    Hayashi, M.5
  • 6
    • 0035863947 scopus 로고    scopus 로고
    • Further evaluation of an in vivo micronucleus test on rat and mouse skin: Results with five skin carcinogens
    • Nishikawa, T., Haresaku, M., Fukushima, A., Nakamura, T., Adachi, M., Matsuda, M. and Hayashi, M. (2002) Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens. Mutat. Res., 513, 93-102.
    • (2002) Mutat. Res , vol.513 , pp. 93-102
    • Nishikawa, T.1    Haresaku, M.2    Fukushima, A.3    Nakamura, T.4    Adachi, M.5    Matsuda, M.6    Hayashi, M.7
  • 7
    • 27744588765 scopus 로고    scopus 로고
    • Further evaluation of the skin micronucleus test: Results obtained using 10 polycyclic aromatic hydrocarbons
    • Nishikawa, T., Nakamura, T., Fukushima, A. and Takagi, Y. (2005) Further evaluation of the skin micronucleus test: results obtained using 10 polycyclic aromatic hydrocarbons. Mutat. Res., 588, 58-63.
    • (2005) Mutat. Res , vol.588 , pp. 58-63
    • Nishikawa, T.1    Nakamura, T.2    Fukushima, A.3    Takagi, Y.4
  • 8
    • 18444398322 scopus 로고    scopus 로고
    • Collaborative validation studies of the in vivo micronucleus test using mouse colonic epithelial cells
    • Ohyama, W., Gonda, M., Miyajima, H. et al. (2002) Collaborative validation studies of the in vivo micronucleus test using mouse colonic epithelial cells. Mutat. Res., 518, 39-45.
    • (2002) Mutat. Res , vol.518 , pp. 39-45
    • Ohyama, W.1    Gonda, M.2    Miyajima, H.3
  • 9
    • 0030740884 scopus 로고    scopus 로고
    • An evaluation of micronucleus induction in bone marrow and in hepatocytes isolated from collagenase perfused liver or from formalin-fixed liver using four-week-old rats treated with known clastogens
    • Parton, J. W. and Garriott, M. L. (1997) An evaluation of micronucleus induction in bone marrow and in hepatocytes isolated from collagenase perfused liver or from formalin-fixed liver using four-week-old rats treated with known clastogens. Environ. Mol. Mutagen., 29, 379-385.
    • (1997) Environ. Mol. Mutagen , vol.29 , pp. 379-385
    • Parton, J.W.1    Garriott, M.L.2
  • 10
    • 2642554637 scopus 로고    scopus 로고
    • A liver micronucleus assay using young rats exposed to diethylnitrosamine: Methodological establishment and evaluation
    • Suzuki, H., Shirotori, T. and Hayashi, M. (2004) A liver micronucleus assay using young rats exposed to diethylnitrosamine: methodological establishment and evaluation. Cytogenet. Genome Res., 104, 299-303.
    • (2004) Cytogenet. Genome Res , vol.104 , pp. 299-303
    • Suzuki, H.1    Shirotori, T.2    Hayashi, M.3
  • 11
    • 0030580937 scopus 로고    scopus 로고
    • Selective induction of micronuclei in the rat/mouse colon and liver by 1,2-dimethylhydrazine: A seven-tissue comparative study
    • Zhurkov, V. S., Sycheva, L. P., Salamatova, O., Vyskubenko, I. F., Feldt, E. G. and Sherenesheva, N. I. (1996) Selective induction of micronuclei in the rat/mouse colon and liver by 1,2-dimethylhydrazine: a seven-tissue comparative study. Mutat. Res., 368, 115-120.
    • (1996) Mutat. Res , vol.368 , pp. 115-120
    • Zhurkov, V.S.1    Sycheva, L.P.2    Salamatova, O.3    Vyskubenko, I.F.4    Feldt, E.G.5    Sherenesheva, N.I.6
  • 12
    • 33846132354 scopus 로고    scopus 로고
    • In vivo erythrocyte micronucleus assay. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test
    • Hayashi, M., MacGregor, J. T., Gatehouse, D. G. et al. (2007) In vivo erythrocyte micronucleus assay. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test. Mutat Res., 627, 10-30.
    • (2007) Mutat Res , vol.627 , pp. 10-30
    • Hayashi, M.1    MacGregor, J.T.2    Gatehouse, D.G.3
  • 13
    • 20144374698 scopus 로고    scopus 로고
    • Evaluation of liver and blood micronucleus assays with 9 chemicals using young rats: A study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS)
    • Suzuki, H., Ikeda, N., Kobayashi et al. (2005) Evaluation of liver and blood micronucleus assays with 9 chemicals using young rats: a study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). Mutat. Res., 583, 133-145.
    • (2005) Mutat. Res , vol.583 , pp. 133-145
    • Suzuki, H.1    Ikeda, N.2    Kobayashi3
  • 14
    • 0031904574 scopus 로고    scopus 로고
    • Evaluation of the rat micronucleus test with bone marrow and peripheral blood: Summary of the 9th collaborative study by CSGMT/JEMS· MMS
    • Wakata, A., Miyamae, Y., Sato, S., Suzuki, T., Morita, T., Asano, N., Awogi, T., Kondo, K. and Hayashi, M. (1998) Evaluation of the rat micronucleus test with bone marrow and peripheral blood: summary of the 9th collaborative study by CSGMT/JEMS· MMS. Environ. Mol. Mutagen., 32, 84-100.
    • (1998) Environ. Mol. Mutagen , vol.32 , pp. 84-100
    • Wakata, A.1    Miyamae, Y.2    Sato, S.3    Suzuki, T.4    Morita, T.5    Asano, N.6    Awogi, T.7    Kondo, K.8    Hayashi, M.9
  • 15
    • 0021048099 scopus 로고
    • A new approach to practical acute toxicity testing
    • Lorke, D. (1983) A new approach to practical acute toxicity testing. Arch. Toxicol., 54, 275-287.
    • (1983) Arch. Toxicol , vol.54 , pp. 275-287
    • Lorke, D.1
  • 16
    • 0025203206 scopus 로고
    • The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange coated slides
    • Hayashi, M., Morita, T., Kodama, K., Sofuni, T. and Ishidate, M., Jr (1990) The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange coated slides. Mutat. Res., 245, 245-249.
    • (1990) Mutat. Res , vol.245 , pp. 245-249
    • Hayashi, M.1    Morita, T.2    Kodama, K.3    Sofuni, T.4    Ishidate Jr, M.5
  • 17
    • 0023860450 scopus 로고
    • A non-invasive micronucleus assay in the rat liver
    • Braithwaite, I. and Ashby, J. (1988) A non-invasive micronucleus assay in the rat liver. Mutat. Res., 203, 23-32.
    • (1988) Mutat. Res , vol.203 , pp. 23-32
    • Braithwaite, I.1    Ashby, J.2
  • 18
    • 0024332230 scopus 로고
    • In vivo micronucleus test using mouse hepatocytes
    • Cliet, I., Fournier, E., Melcion, C. and Cordier, A. (1989) In vivo micronucleus test using mouse hepatocytes. Mutat. Res., 216, 321-326.
    • (1989) Mutat. Res , vol.216 , pp. 321-326
    • Cliet, I.1    Fournier, E.2    Melcion, C.3    Cordier, A.4
  • 19
    • 0014788551 scopus 로고
    • Tables for determining the statistical significance of mutation frequencies
    • Kastenbaum, M. A. and Bowman, K. O. (1970) Tables for determining the statistical significance of mutation frequencies. Mutat. Res., 9, 527-549.
    • (1970) Mutat. Res , vol.9 , pp. 527-549
    • Kastenbaum, M.A.1    Bowman, K.O.2
  • 20
    • 0021867621 scopus 로고
    • Concomitant observations of UDS in the liver and micronuclei in the bone marrow of rats exposed to cyclophosphamide or 2-acetylaminofluorene
    • Ashby, J. and Beije, B. (1985) Concomitant observations of UDS in the liver and micronuclei in the bone marrow of rats exposed to cyclophosphamide or 2-acetylaminofluorene. Mutat. Res., 150, 383-392.
    • (1985) Mutat. Res , vol.150 , pp. 383-392
    • Ashby, J.1    Beije, B.2
  • 21
    • 0029746045 scopus 로고    scopus 로고
    • 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation
    • Verna, L., Whysner, J. and Williams, G. M. (1996) 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation. Pharmacol. Ther., 71, 83-105.
    • (1996) Pharmacol. Ther , vol.71 , pp. 83-105
    • Verna, L.1    Whysner, J.2    Williams, G.M.3
  • 22
  • 23
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
    • Mirsalis, J. C., Tyson, C. K. and Butterworth, B. E. (1982) Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ. Mutagen., 4, 553-562.
    • (1982) Environ. Mutagen , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, C.K.2    Butterworth, B.E.3
  • 24
    • 0026716863 scopus 로고
    • Sex-specific cytochrome P450 as a cause of sex-and species-related differences in drug toxicity
    • Kato, R. and Yamazoe, Y. (1992) Sex-specific cytochrome P450 as a cause of sex-and species-related differences in drug toxicity. Toxicol. Lett., 64/65, 661-667.
    • (1992) Toxicol. Lett , vol.64-65 , pp. 661-667
    • Kato, R.1    Yamazoe, Y.2
  • 25
    • 0025930779 scopus 로고
    • Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene using the rat micronucleus test and rat liver UDS assay
    • George, E. and Westmoreland, C. (1991) Evaluation of the in vivo genotoxicity of the structural analogues 2,6-diaminotoluene using the rat micronucleus test and rat liver UDS assay. Carcinogenesis, 12, 2233-2237.
    • (1991) Carcinogenesis , vol.12 , pp. 2233-2237
    • George, E.1    Westmoreland, C.2
  • 26
    • 0026800513 scopus 로고
    • A quantitative assessment of the cytotoxicity associated with chromosomal aberration detection in Chinese hamster ovary cells
    • Armstrong, M. J., Bean, C. L. and Galloway, S. M. (1992) A quantitative assessment of the cytotoxicity associated with chromosomal aberration detection in Chinese hamster ovary cells. Mutat. Res., 265, 45-60.
    • (1992) Mutat. Res , vol.265 , pp. 45-60
    • Armstrong, M.J.1    Bean, C.L.2    Galloway, S.M.3
  • 27
    • 2942553336 scopus 로고
    • Some aromatic amines and related nitro compounds-hair dyes, colouring agents and miscellaneous industrial chemicals
    • International Agency for Research on Cancer , International Agency for Research on Cancer, Lyon, France
    • International Agency for Research on Cancer (1979) Some aromatic amines and related nitro compounds-hair dyes, colouring agents and miscellaneous industrial chemicals. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, International Agency for Research on Cancer, Lyon, France, Vol. 16, pp. 83-95.
    • (1979) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man , vol.16 , pp. 83-95
  • 29
    • 0027475874 scopus 로고
    • The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice
    • Suzuki, T., Hayashi, M., Sofuni, T. and Myhr, B. C. (1993) The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice. Mutat. Res., 285, 219-224.
    • (1993) Mutat. Res , vol.285 , pp. 219-224
    • Suzuki, T.1    Hayashi, M.2    Sofuni, T.3    Myhr, B.C.4
  • 30
    • 0022770739 scopus 로고
    • Letter to the editor
    • Ashby, J. (1986) Letter to the editor. Mutagenesis, 1, 309-317.
    • (1986) Mutagenesis , vol.1 , pp. 309-317
    • Ashby, J.1
  • 32
    • 0008274595 scopus 로고    scopus 로고
    • Hydrazine monohydrochloride and 1,2-dimethylhydrazine dihydrochloride induce micronuclei in rats
    • Oka, H., Ohuchida, A., Suzuki, T., Sofuni, T. and Hayashi, M. (1996) Hydrazine monohydrochloride and 1,2-dimethylhydrazine dihydrochloride induce micronuclei in rats. MMS. Commun., 4, 99-107.
    • (1996) MMS. Commun , vol.4 , pp. 99-107
    • Oka, H.1    Ohuchida, A.2    Suzuki, T.3    Sofuni, T.4    Hayashi, M.5
  • 33
    • 0003459751 scopus 로고    scopus 로고
    • Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide
    • International Agency for Research on Cancer , International Agency for Research on Cancer, Lyon, France
    • International Agency for Research on Cancer (1999) Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, International Agency for Research on Cancer, Lyon, France, Vol. 71, pp. 947-989.
    • (1999) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man , vol.71 , pp. 947-989
  • 34
    • 0021125238 scopus 로고
    • Dinitrotoluene: Acute toxicity, oncogenicity, genotoxicity, and metabolism
    • Rickert, D. E., Butterworth, B. E. and Popp, J. A. (1984) Dinitrotoluene: acute toxicity, oncogenicity, genotoxicity, and metabolism. Rev. Toxicol., 13, 217-234.
    • (1984) Rev. Toxicol , vol.13 , pp. 217-234
    • Rickert, D.E.1    Butterworth, B.E.2    Popp, J.A.3
  • 35
    • 0022472704 scopus 로고
    • The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens
    • Ashby, J. (1986) The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens. Mutagenesis, 1, 3-16.
    • (1986) Mutagenesis , vol.1 , pp. 3-16
    • Ashby, J.1
  • 36
    • 58149140969 scopus 로고    scopus 로고
    • Printing processes and printing inks, carbon black and some nitro compounds
    • International Agency for Research on Cancer , International Agency for Research on Cancer, Lyon, France
    • International Agency for Research on Cancer (1996) Printing processes and printing inks, carbon black and some nitro compounds. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, International Agency for Research on Cancer, Lyon, France, Vol. 65, pp. 309-368.
    • (1996) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man , vol.65 , pp. 309-368
  • 37
    • 0020672031 scopus 로고
    • The induction of chromosomal damage in rat hepatocytes and lymphocytes. I. Time-dependent changes of the clastogenic effects of diethylnitrosamine, dimethylnitrosamine and ethyl methanesulfonate
    • Tates, A. D., Neuteboom, I., de Vogel, N. and den Engelse, L. (1983) The induction of chromosomal damage in rat hepatocytes and lymphocytes. I. Time-dependent changes of the clastogenic effects of diethylnitrosamine, dimethylnitrosamine and ethyl methanesulfonate. Mutat. Res., 107, 131-151.
    • (1983) Mutat. Res , vol.107 , pp. 131-151
    • Tates, A.D.1    Neuteboom, I.2    de Vogel, N.3    den Engelse, L.4
  • 38
    • 0022965906 scopus 로고
    • Persistence of preclastogenic damage in hepatocytes of rats exposed to ethylnitrosourea, diethylnitrosamine, dimethylnitrosamine and methyl methanesulfonate. Correlation with DNA O-alkylation
    • Tates, A. D., Neuteboom, I., Rotteveel, A. H. M., de Vogel, N., Menkveld, G. J. and den Engelse, L. (1986) Persistence of preclastogenic damage in hepatocytes of rats exposed to ethylnitrosourea, diethylnitrosamine, dimethylnitrosamine and methyl methanesulfonate. Correlation with DNA O-alkylation. Carcinogenesis, 7, 1053-1058.
    • (1986) Carcinogenesis , vol.7 , pp. 1053-1058
    • Tates, A.D.1    Neuteboom, I.2    Rotteveel, A.H.M.3    de Vogel, N.4    Menkveld, G.J.5    den Engelse, L.6
  • 39
    • 0019563951 scopus 로고
    • Some antineoplastic and immunosuppressive agents
    • International Agency for Research on Cancer , International Agency for Research on Cancer, Lyon, France
    • International Agency for Research on Cancer (1981) Some antineoplastic and immunosuppressive agents. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, International Agency for Research on Cancer, Lyon, France, Vol. 26, pp. 217-235.
    • (1981) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man , vol.26 , pp. 217-235
  • 40
    • 0030839678 scopus 로고    scopus 로고
    • Simple detection of chemical mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrrow)
    • Sasaki, Y. F., Nishidate, E., Izumiyama, F., Matsusaka, N. and Tsuda, S. (1997) Simple detection of chemical mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrrow). Mutat. Res., 391, 215-231.
    • (1997) Mutat. Res , vol.391 , pp. 215-231
    • Sasaki, Y.F.1    Nishidate, E.2    Izumiyama, F.3    Matsusaka, N.4    Tsuda, S.5
  • 41
    • 0027141730 scopus 로고
    • An assessment of the in vitro hepatocyte micronucleus assay
    • Müller, K., Kasper, P. and Müller, L. (1993) An assessment of the in vitro hepatocyte micronucleus assay. Mutat. Res., 292, 213-224.
    • (1993) Mutat. Res , vol.292 , pp. 213-224
    • Müller, K.1    Kasper, P.2    Müller, L.3
  • 42
    • 2542530180 scopus 로고
    • Early induction of in vivo-in vitro hepatocyte replicative DNA synthesis (RDS) by nongenotoxic and genotoxic hepatocarcinogens in male F344 rats and B6C3F1 mice
    • Yoshikawa, K. (1995) Early induction of in vivo-in vitro hepatocyte replicative DNA synthesis (RDS) by nongenotoxic and genotoxic hepatocarcinogens in male F344 rats and B6C3F1 mice. J. Toxicol. Pathol., 8, 291-302.
    • (1995) J. Toxicol. Pathol , vol.8 , pp. 291-302
    • Yoshikawa, K.1
  • 43
    • 0029559743 scopus 로고
    • Cell proliferation as a determining factor for the carcinogenicity of chemicals: Studies with mutagenic carcinogens and mutagenic noncarcinogens
    • Cunningham, M. L. and Matthews, H. B. (1995) Cell proliferation as a determining factor for the carcinogenicity of chemicals: studies with mutagenic carcinogens and mutagenic noncarcinogens. Toxicol. Lett., 82/83, 9-14.
    • (1995) Toxicol. Lett , vol.82-83 , pp. 9-14
    • Cunningham, M.L.1    Matthews, H.B.2
  • 44
    • 0021152516 scopus 로고
    • Azoreductase activity of Sprague-Dawley and Wistar-derived rats towards both carcinogenic and non-carcinogenic analogues of 4-dimethylaminophenylazobenzene (DAB)
    • Elliott, B. M. (1984) Azoreductase activity of Sprague-Dawley and Wistar-derived rats towards both carcinogenic and non-carcinogenic analogues of 4-dimethylaminophenylazobenzene (DAB). Carcinogenesis, 5, 1051-1055.
    • (1984) Carcinogenesis , vol.5 , pp. 1051-1055
    • Elliott, B.M.1
  • 45
    • 0020002066 scopus 로고
    • Differences in liver homogenates from Donryu, Fischer, Sprague-Dawley and Wistar strains of rat in the drug-metabolizing enzyme assay and the Salmonella/hepatic S9 activation test
    • Yoshikawa, K., Nohmi, T., Miyata, R., Ishidate, M., Jr, Ozawa, N., Isobe, M., Watanabe, T., Kada, T. and Kawachi, T. (1982) Differences in liver homogenates from Donryu, Fischer, Sprague-Dawley and Wistar strains of rat in the drug-metabolizing enzyme assay and the Salmonella/hepatic S9 activation test. Mutat. Res., 96, 167-186.
    • (1982) Mutat. Res , vol.96 , pp. 167-186
    • Yoshikawa, K.1    Nohmi, T.2    Miyata, R.3    Ishidate Jr, M.4    Ozawa, N.5    Isobe, M.6    Watanabe, T.7    Kada, T.8    Kawachi, T.9
  • 46
    • 0026082943 scopus 로고
    • Strain differences in in vitro rat hepatocyte unscheduled DNA synthesis (UDS): Effect of UV is independent of strain while increased sensitivity is apparent using Fischer-344 instead of Sprague-Dawley rats
    • Harbach, P. R., Wiser, S. K., Smith, A. L., Grzegorczyk, C. R. and Aaron, C. S. (1991) Strain differences in in vitro rat hepatocyte unscheduled DNA synthesis (UDS): effect of UV is independent of strain while increased sensitivity is apparent using Fischer-344 instead of Sprague-Dawley rats. Mutat. Res., 252, 149-155.
    • (1991) Mutat. Res , vol.252 , pp. 149-155
    • Harbach, P.R.1    Wiser, S.K.2    Smith, A.L.3    Grzegorczyk, C.R.4    Aaron, C.S.5
  • 47
    • 0023899291 scopus 로고
    • Pre-and post weaning development of drug-metabolizing enzyme activities in small intestine and liver of rats
    • de Waziers, I., Biosset, M. and Attela, S. (1988) Pre-and post weaning development of drug-metabolizing enzyme activities in small intestine and liver of rats. Drug Metab. Dispos., 16, 310-315.
    • (1988) Drug Metab. Dispos , vol.16 , pp. 310-315
    • de Waziers, I.1    Biosset, M.2    Attela, S.3


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