Evaluation of a liver micronucleus assay in young rats (IV): A study using a double-dosing/single-sampling method by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS)

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 698, Issue 1-2, 2010, Pages 24-29

  Takasawa, Hironao ^a   Suzuki, Hiroshi ^b   Ogawa, Izumi ^c   Shimada, Yasushi ^d   Kobayashi, Kazuo ^e   Terashima, Yukari ^e   Matsumoto, Hirotaka ^f   Oshida, Keiyu ^g   Ohta, Ryo ^f   Imamura, Tadashi ^b   Miyazaki, Atsushi ^b   Kawabata, Masayoshi ^a   Minowa, Shigenori ^a   Maeda, Akihisa ^g   Hayashi, Makoto ^h  

^a LSI MEDIENCE CORPORATION   (Japan)

^b N   (Japan)

^c NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

^d Hokko Chemical Industry Co Ltd ^*  (Japan)

^e KISSEI PHARMACEUTICAL CO LTD   (Japan)

^f HATANO RESEARCH INSTITUTE   (Japan)

^g TORAY INDUSTRIES INC   (Japan)

^h Biosafety Research Center   (Japan)

Author keywords

Double dosing single sampling method; Liver micronucleus assay; Single dosing triple sampling method; Young rats

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 2,4 DIAMINOTOLUENE; 2,4 DINITROTOLUENE; 2,6 DINITROTOLUENE; 4 DIMETHYLAMINOAZOBENZENE; CARCINOGEN; DIETHYLNITROSAMINE; ENVIRONMENTAL MUTAGEN; MITOMYCIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG MEGADOSE; GENOTOXICITY; LABORATORY; LIVER; LIVER CELL; LIVER MICRONUCLEUS ASSAY; LIVER PERFUSION; LOW DRUG DOSE; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MUTAGEN TESTING; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SAMPLING; SOCIETY; VALIDATION PROCESS; AGE; ANIMAL; DRUG EFFECT; EVALUATION; FISCHER 344 RAT; METHODOLOGY;

ANIMALIA; MAMMALIA; RATTUS;

AGE FACTORS; ANIMALS; CARCINOGENS; LIVER; MALE; MICRONUCLEUS TESTS; RATS; RATS, INBRED F344;

EID: 77954893923     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.02.010     Document Type: Article

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