Digoxin attenuates acute cardiac allograft rejection by antagonizing RORγt activity

Transplantation

Volumn 95, Issue 3, 2013, Pages 434-441

  Wu, Jie ^a   Zhou, Cheng ^a   Chen, Wenhao ^b   Xie, Aini ^a,b   Li, Jun ^a   Wang, Sihua ^a   Ye, Ping ^a   Wang, Wenshuo ^a   Xia, Jiahong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Allograft rejection; Cardiac transplantation; Digoxin; ROR t; Th17

Indexed keywords

CYTOKINE; DIGOXIN; DIMETHYL SULFOXIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RORGAMMAT; UNCLASSIFIED DRUG;

ACUTE CARDIAC ALLOGRAFT REJECTION; ACUTE GRAFT REJECTION; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; FLOW CYTOMETRY; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTOLOGY; IN VITRO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; SPLEEN; T LYMPHOCYTE SUBPOPULATION; TH17 CELL;

ANIMALS; CARDIOTOXINS; CELL DIFFERENTIATION; DIGOXIN; DIMETHYL SULFOXIDE; GRAFT REJECTION; HEART TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, ANIMAL; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TRANSPLANTATION, HETEROTOPIC; TRANSPLANTATION, HOMOLOGOUS;

EID: 84873412807     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31827a48f5     Document Type: Article

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