ROR blockers inhibit T H 17 cells

Nature Reviews Neurology

Volumn 7, Issue 6, 2011, Pages 303-

  Ozerlat, Iley ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

AUTOIMMUNE DISEASE; DISEASE COURSE; DRUG MECHANISM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MULTIPLE SCLEROSIS; NOTE; PATHOLOGY; PRIORITY JOURNAL; RECEPTOR BLOCKING; TH17 CELL;

EID: 79958226296     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2011.75     Document Type: Note

References (3)

1. Solt, L. A., et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature 472, 491494 (2011)
2. Huh, J. R., et al. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORt activity. Nature 472, 486490 (2011)
3. Jetten, A. M. A helping hand against autoimmunity. Nature 472, 421422 (2011)