-
3
-
-
80053088189
-
Hepatocellular carcinoma
-
El-Serag HB. Hepatocellular carcinoma. N Engl J Med 2011; 365: 1118-1127.
-
(2011)
N Engl J Med
, vol.365
, pp. 1118-1127
-
-
El-Serag, H.B.1
-
4
-
-
35548930209
-
The emerging roles of forkhead box (Fox) proteins in cancer
-
Myatt SS, Lam EW. The emerging roles of forkhead box (Fox) proteins in cancer. Nat Rev Cancer 2007; 7: 847-859.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 847-859
-
-
Myatt, S.S.1
Lam, E.W.2
-
5
-
-
84860390076
-
Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, et al. Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. J Cell Biochem 2011; 112: 2296-2306.
-
(2011)
J Cell Biochem
, vol.112
, pp. 2296-2306
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Banerjee, S.5
Ahmad, A.6
-
6
-
-
78650802382
-
Deregulation of FoxM1b leads to tumour metastasis
-
Park HJ, Gusarova G, Wang Z, Carr JR, Li J, Kim KH, et al. Deregulation of FoxM1b leads to tumour metastasis. EMBO Mol Med 2011; 3: 21-34.
-
(2011)
EMBO Mol Med
, vol.3
, pp. 21-34
-
-
Park, H.J.1
Gusarova, G.2
Wang, Z.3
Carr, J.R.4
Li, J.5
Kim, K.H.6
-
7
-
-
79951849322
-
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis
-
Zhang H, Meng F, Liu G, Zhang B, Zhu J, Wu F, et al. Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res 2011; 71: 1292-1301.
-
(2011)
Cancer Res
, vol.71
, pp. 1292-1301
-
-
Zhang, H.1
Meng, F.2
Liu, G.3
Zhang, B.4
Zhu, J.5
Wu, F.6
-
8
-
-
77950197610
-
Nuclear Janus-activated kinase 2/nuclear factor 1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing Forkhead box F1
-
Nilsson J, Helou K, Kovacs A, Bendahl PO, Bjursell G, Ferno M, et al. Nuclear Janus-activated kinase 2/nuclear factor 1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing Forkhead box F1. Cancer Res 2010; 70: 2020-2029.
-
(2010)
Cancer Res
, vol.70
, pp. 2020-2029
-
-
Nilsson, J.1
Helou, K.2
Kovacs, A.3
Bendahl, P.O.4
Bjursell, G.5
Ferno, M.6
-
9
-
-
79651473733
-
FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers
-
Tang Y, Shu G, Yuan X, Jing N, Song J. FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers. Cell Res 2011; 21: 316-326.
-
(2011)
Cell Res
, vol.21
, pp. 316-326
-
-
Tang, Y.1
Shu, G.2
Yuan, X.3
Jing, N.4
Song, J.5
-
10
-
-
77950293595
-
Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer
-
Song Y, Washington MK, Crawford HC. Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Cancer Res 2010; 70: 2115-2125.
-
(2010)
Cancer Res
, vol.70
, pp. 2115-2125
-
-
Song, Y.1
Washington, M.K.2
Crawford, H.C.3
-
11
-
-
66349107985
-
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC
-
Calvisi DF, Pinna F, Ladu S, Pellegrino R, Simile MM, Frau M, et al. Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC. Gut 2009; 58: 679-687.
-
(2009)
Gut
, vol.58
, pp. 679-687
-
-
Calvisi, D.F.1
Pinna, F.2
Ladu, S.3
Pellegrino, R.4
Simile, M.M.5
Frau, M.6
-
12
-
-
84865146153
-
Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinoma
-
Xia L, Huang W, Tian D, Zhu H, Zhang Y, Hu H, et al. Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinoma. J Hepatol 2012; 57: 600-612.
-
(2012)
J Hepatol
, vol.57
, pp. 600-612
-
-
Xia, L.1
Huang, W.2
Tian, D.3
Zhu, H.4
Zhang, Y.5
Hu, H.6
-
13
-
-
84857126252
-
Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth
-
Seo S, Singh HP, Lacal PM, Sasman A, Fatima A, Liu T, et al. Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth. Proc Natl Acad Sci U S A 2012; 109: 2015-2020.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2015-2020
-
-
Seo, S.1
Singh, H.P.2
Lacal, P.M.3
Sasman, A.4
Fatima, A.5
Liu, T.6
-
14
-
-
33745099879
-
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development
-
Seo S, Fujita H, Nakano A, Kang M, Duarte A, Kume T. The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol 2006; 294: 458-470.
-
(2006)
Dev Biol
, vol.294
, pp. 458-470
-
-
Seo, S.1
Fujita, H.2
Nakano, A.3
Kang, M.4
Duarte, A.5
Kume, T.6
-
15
-
-
0035883744
-
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis
-
Kume T, Jiang H, Topczewska JM, Hogan BL. The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev 2001; 15: 2470-2482.
-
(2001)
Genes Dev
, vol.15
, pp. 2470-2482
-
-
Kume, T.1
Jiang, H.2
Topczewska, J.M.3
Hogan, B.L.4
-
16
-
-
70450231796
-
Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells
-
Savage J, Voronova A, Mehta V, Sendi-Mukasa F, Skerjanc IS. Canonical Wnt signaling regulates Foxc1/2 expression in P19 cells. Differentiation 2010; 79: 31-40.
-
(2010)
Differentiation
, vol.79
, pp. 31-40
-
-
Savage, J.1
Voronova, A.2
Mehta, V.3
Sendi-Mukasa, F.4
Skerjanc, I.S.5
-
17
-
-
33744511922
-
Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade
-
Berry FB, Mirzayans F, Walter MA. Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade. J Biol Chem 2006; 281: 10098-10104.
-
(2006)
J Biol Chem
, vol.281
, pp. 10098-10104
-
-
Berry, F.B.1
Mirzayans, F.2
Walter, M.A.3
-
18
-
-
52949122883
-
Cell type-specific DNA methylation patterns in the human breast
-
Bloushtain-Qimron N, Yao J, Snyder EL, Shipitsin M, Campbell LL, Mani SA, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 2008; 105: 14076-14081.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14076-14081
-
-
Bloushtain-Qimron, N.1
Yao, J.2
Snyder, E.L.3
Shipitsin, M.4
Campbell, L.L.5
Mani, S.A.6
-
19
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A 2010; 107: 15449-15454.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
-
20
-
-
84863791651
-
The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression
-
Sizemore ST, Keri RA. The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression. J Biol Chem 2012; 287: 24631-24640.
-
(2012)
J Biol Chem
, vol.287
, pp. 24631-24640
-
-
Sizemore, S.T.1
Keri, R.A.2
-
21
-
-
77952821751
-
FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer
-
Ray PS, Wang J, Qu Y, Sim MS, Shamonki J, Bagaria SP, et al. FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer. Cancer Res 2010; 70: 3870-3876.
-
(2010)
Cancer Res
, vol.70
, pp. 3870-3876
-
-
Ray, P.S.1
Wang, J.2
Qu, Y.3
Sim, M.S.4
Shamonki, J.5
Bagaria, S.P.6
-
22
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-454.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
23
-
-
67650996754
-
Biomarkers for epithelial-mesenchymal transitions
-
Zeisberg M, Neilson EG. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest 2009; 119: 1429-1437.
-
(2009)
J Clin Invest
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
-
24
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119: 1420-1428.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
25
-
-
33745288277
-
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene
-
Kim M, Gans JD, Nogueira C, Wang A, Paik JH, Feng B, et al. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 2006; 125: 1269-1281.
-
(2006)
Cell
, vol.125
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
Wang, A.4
Paik, J.H.5
Feng, B.6
-
26
-
-
70349747017
-
NEDD9 promotes oncogenic signaling in mammary tumor development
-
Izumchenko E, Singh MK, Plotnikova OV, Tikhmyanova N, Little JL, Serebriiskii IG, et al. NEDD9 promotes oncogenic signaling in mammary tumor development. Cancer Res 2009; 69: 7198-7206.
-
(2009)
Cancer Res
, vol.69
, pp. 7198-7206
-
-
Izumchenko, E.1
Singh, M.K.2
Plotnikova, O.V.3
Tikhmyanova, N.4
Little, J.L.5
Serebriiskii, I.G.6
-
27
-
-
79957912993
-
EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis
-
Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, Feng H, et al. EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. Cancer Res 2011; 71: 4028-4039.
-
(2011)
Cancer Res
, vol.71
, pp. 4028-4039
-
-
Cheng, A.S.1
Lau, S.S.2
Chen, Y.3
Kondo, Y.4
Li, M.S.5
Feng, H.6
-
28
-
-
64749106861
-
Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas
-
Yu B, Yang X, Xu Y, Yao G, Shu H, Lin B, et al. Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas. J Hepatol 2009; 50: 948-957.
-
(2009)
J Hepatol
, vol.50
, pp. 948-957
-
-
Yu, B.1
Yang, X.2
Xu, Y.3
Yao, G.4
Shu, H.5
Lin, B.6
-
29
-
-
84860319933
-
MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling
-
Cha YH, Kim NH, Park C, Lee I, Kim HS, Yook JI. MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling. Cell Cycle 2012; 11: 1273-1281.
-
(2012)
Cell Cycle
, vol.11
, pp. 1273-1281
-
-
Cha, Y.H.1
Kim, N.H.2
Park, C.3
Lee, I.4
Kim, H.S.5
Yook, J.I.6
-
30
-
-
84857979406
-
MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer
-
Hirata H, Hinoda Y, Ueno K, Nakajima K, Ishii N, Dahiya R. MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer. Carcinogenesis 2012; 33: 501-508.
-
(2012)
Carcinogenesis
, vol.33
, pp. 501-508
-
-
Hirata, H.1
Hinoda, Y.2
Ueno, K.3
Nakajima, K.4
Ishii, N.5
Dahiya, R.6
-
31
-
-
84866549389
-
Dickkopf 4 (DKK4) acts on Wnt/beta-catenin pathway by influencing beta-catenin in hepatocellular carcinoma
-
Jan 16. doi: 10.1038/onc.2011.580
-
Fatima S, Lee NP, Tsang FH, Kolligs FT, Ng IO, Poon RT, et al. Dickkopf 4 (DKK4) acts on Wnt/beta-catenin pathway by influencing beta-catenin in hepatocellular carcinoma. Oncogene 2012 Jan 16. doi: 10.1038/onc.2011.580.
-
(2012)
Oncogene
-
-
Fatima, S.1
Lee, N.P.2
Tsang, F.H.3
Kolligs, F.T.4
Ng, I.O.5
Poon, R.T.6
-
32
-
-
84856191525
-
Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers
-
White BD, Chien AJ, Dawson DW. Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers. Gastroenterology 2012; 142: 219-232.
-
(2012)
Gastroenterology
, vol.142
, pp. 219-232
-
-
White, B.D.1
Chien, A.J.2
Dawson, D.W.3
-
33
-
-
77949654113
-
Mechanisms of HBV-related hepatocarcinogenesis
-
Neuveut C, Wei Y, Buendia MA. Mechanisms of HBV-related hepatocarcinogenesis. J Hepatol 2010; 52: 594-604.
-
(2010)
J Hepatol
, vol.52
, pp. 594-604
-
-
Neuveut, C.1
Wei, Y.2
Buendia, M.A.3
-
34
-
-
77951176116
-
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
-
Chen L, Chan TH, Yuan YF, Hu L, Huang J, Ma S, et al. CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J Clin Invest 2010; 120: 1178-1191.
-
(2010)
J Clin Invest
, vol.120
, pp. 1178-1191
-
-
Chen, L.1
Chan, T.H.2
Yuan, Y.F.3
Hu, L.4
Huang, J.5
Ma, S.6
-
35
-
-
77956635530
-
Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion
-
Ding W, You H, Dang H, LeBlanc F, Galicia V, Lu SC, et al. Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. HEPATOLOGY 2010; 52: 945-953.
-
(2010)
HEPATOLOGY
, vol.52
, pp. 945-953
-
-
Ding, W.1
You, H.2
Dang, H.3
LeBlanc, F.4
Galicia, V.5
Lu, S.C.6
-
36
-
-
44449144396
-
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008; 14: 818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
37
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
-
38
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, Garcia De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2000; 2: 84-89.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Dominguez, D.4
Monfar, M.5
Baulida, J.6
Garcia De Herreros, A.7
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