15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARγ

Journal of Neurochemistry

Volumn 124, Issue 4, 2013, Pages 536-547

  Haskew Layton, Renée E ^a   Payappilly, Jimmy B ^a   Xu, Hongbin ^b   Bennett, Steffany A L ^b   Ratan, Rajiv R ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

astrocytes; neuroprotection; Nrf2; PPAR ; vitamin E

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; GLUTATHIONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR NRF2; TROGLITAZONE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRESS; CONTROLLED STUDY; GENE INDUCTION; GENE TARGETING; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LIPID INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; ASTROCYTES; CELL COUNT; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GLUTATHIONE; HOMOCYSTEINE; HYPOGLYCEMIC AGENTS; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PPAR GAMMA; PROSTAGLANDIN D2; RATS; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES; TIME FACTORS;

EID: 84873308914     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12107     Document Type: Article

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