Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 11, 2012, Pages 2924-2933

  Shih, Ping Hsiao ^a   Hwang, Sam Long ^b   Yeh, Chi Tai ^c,d   Yen, Gow Chin ^a,e  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

anthocyanidin; chronic nonalcoholic fatty liver disease; oxidative stress; synergistic effect; thiazolidinedione

Indexed keywords

ANTHOCYANIDIN; ANTIOXIDANT ENZYME; APOPTOTIC CELL DEATH; C-JUN N-TERMINAL KINASE; CYANIDIN; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED KINASE; FIBROGENESIS; HEPATOTOXICITY; LIPID METABOLISMS; MITOGEN ACTIVATED PROTEIN KINASE; NON-ALCOHOLIC FATTY LIVER DISEASE; NON-ALCOHOLIC STEATOHEPATITIS; NUCLEAR FACTORS; OXIDATIVE DAMAGE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; STRESS-INDUCED; SYNERGISTIC EFFECT; THIAZOLIDINEDIONES; TRANSDUCTION PATHWAYS;

CELL DEATH; ENZYME ACTIVITY; GENES; METABOLISM; PHYSIOLOGY; TRANSCRIPTION FACTORS;

OXIDATIVE STRESS;

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTHOCYANIN; CHROMAN DERIVATIVE; CYANIDIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; TROGLITAZONE;

ANIMAL; ARTICLE; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; FATTY LIVER; GENETICS; HUMAN; METABOLISM; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTHOCYANINS; CELL LINE, TUMOR; CHROMANS; DRUG SYNERGISM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY LIVER; HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RATS; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES;

EID: 84858771324     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf300005v     Document Type: Article

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