Nox2 Is Required for Macrophage Chemotaxis towards CSF-1

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Chaubey, Sanjay ^a   Jones, Gareth E ^b   Shah, Ajay M ^a   Cave, Alison C ^a   Wells, Claire M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CSF1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; ENZYME PHOSPHORYLATION; INTRACELLULAR SIGNALING; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; CELL MIGRATION ASSAYS, MACROPHAGE; CHEMOTAXIS; IMMUNOBLOTTING; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; NADPH OXIDASE; TIME-LAPSE IMAGING;

EID: 84873258343     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054869     Document Type: Article

References (53)

1. Lambeth JD (2004) NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4, 181-189.
2. Griendling KK, Sorescu D and Ushio-Fukai M (2000b) NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86, 494-501.
3. Griendling KK, Sorescu D, Lassegue B and Ushio-Fukai M (2000a) Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler. Thromb. Vasc. Biol. 20, 2175-2183.
4. Lassegue B, San MA, and Griendling KK (2012) Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ. Res. 110, 1364-1390.
5. Judkins CP, Diep H, Broughton BR, Mast AE, Hooker EU, et al. (2010) Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am. J. Physiol Heart Circ. Physiol 298, H24-H32.
6. Stokes KY, Clanton EC, Russell JM, Ross CR, and Granger DN (2001) NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion. Circ. Res. 88, 499-505.
7. Moldovan L, Moldovan NI, Sohn RH, Parikh SA, Goldschmidt-Clermont PJ (2000) Redox changes of cultured endothelial cells and actin dynamics. Circ. Res. 86, 549-557.
8. Lee MY, San MA, Mehta PK, Dikalova AE, Garrido AM, et al. (2009) Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler. Thromb. Vasc. Biol. 29, 480-487.
9. San MA, Lee MY, Williams HC, Mizuno K, Lassegue B, et al. (2008) Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circ. Res. 102, 432-438.
10. Umanskiy K, Robinson C, Cave C, Williams MA, Lentsch AB, et al. (2003) NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation. Surgery 134, 378-383.
11. Clempus RE, Sorescu D, Dikalova AE, Pounkova L, Jo P, et al. (2007) Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype. Arterioscler. Thromb. Vasc. Biol. 27, 42-48.
12. Diaz B, Shani G, Pass I, Anderson D, Quintavalle M, et al. (2009) Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. Sci. Signal. 2, ra53.
13. Ushio-Fukai M, Tang Y, Fukai T, Dikalov SI, Ma Y, et al. (2002) Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ. Res. 91, 1160-1167.
14. Ikeda S, Ushio-Fukai M, Zuo L, Tojo T, Dikalov S, et al. (2005) Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis. Circ. Res. 96, 467-475.
15. Colavitti R, Pani G, Bedogni B, Anzevino R, Borrello S, et al. (2002) Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR. J. Biol. Chem. 277, 3101-3108.
16. Bae YS, Lee JH, Choi SH, Kim S, Almazan F, et al. (2009) Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ. Res. 104, 210-8, 21p.
17. Wells CM, Walmsley M, Ooi S, Tybulewicz V, and Ridley AJ (2004) Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J. Cell Sci. 117, 1259-1268.
18. Allen WE, Zicha D, Ridley AJ and Jones GE (1998) A role for Cdc42 in macrophage chemotaxis. J. Cell Biol. 141, 1147-1157.
19. Smith SD, Jaffer ZM, Chernoff J, and Ridley AJ (2008) PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J. Cell Sci. 121, 3729-3736.
20. Sester DP, Trieu A, Brion K, Schroder K, Ravasi T, et al. (2005) LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action. Immunobiology 210, 97-107.
21. Ridley AJ (2004) Pulling back to move forward. Cell 116, 357-358.
22. Pankov R, Endo Y, Even-Ram S, Araki M, Clark K, et al. (2005) A Rac switch regulates random versus directionally persistent cell migration. J. Cell Biol 170, 793-802.
23. Merlot S and Firtel RA (2003) Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J. Cell Sci. 116, 3471-3478.
24. Ward SG (2004) Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol. 25, 67-74.
25. Leslie NR, Yang X, Downes CP, and Weijer CJ (2007) PtdIns(3,4,5)P(3)-dependent and-independent roles for PTEN in the control of cell migration. Curr. Biol. 17, 115-125.
26. Procko E and McColl SR (2005) Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors. Bioessays 27, 153-163.
27. Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, et al. (2003) Redox regulation of PI 3-kinase signalling via inactivation of PTEN. EMBO J. 22, 5501-5510.
28. Denu JM and Tanner KG (1998) Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry 37, 5633-5642.
29. Lee SR, Kwon KS, Kim SR, and Rhee SG (1998) Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273, 15366-15372.
30. Ponting CP (1996) Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains? Protein Sci. 5, 2353-2357.
31. Ellson CD, Gobert-Gosse S, Anderson KE, Davidson K, Erdjument-Bromage H, et al. (2001) PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat. Cell Biol. 3, 679-682.
32. Itoh RE, Kurokawa K, Ohba Y, Yoshizaki H, Mochizuki N, et al. (2002) Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol. Cell Biol. 22, 6582-6591.
33. Srinivasan, S Wang, F Glavas, S Ott, A Hofmann, F et al. (2003). Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J. Cell Biol. 160, 375-385.
34. Etienne-Manneville S and Hall A (2002) Rho GTPases in cell biology. Nature 420, 629-635.
35. Diebold BA, Fowler B, Lu J, Dinauer MC, and Bokoch GM (2004) Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. J. Biol. Chem. 279, 28136-28142.
36. Kim JH, Na HJ, Kim CK, Kim JY, Ha KS, et al. (2008) The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation. Free Radic. Biol. Med. 45, 885-896.
37. Touyz RM, Yao G, Quinn MT, Pagano PJ, and Schiffrin EL (2005) p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II. Arterioscler. Thromb. Vasc. Biol. 25, 512-518.
38. Morimatsu T, Kawagoshi A, Yoshida K, and Tamura M (1997) Actin enhances the activation of human neutrophil NADPH oxidase in a cell-free system. Biochem. Biophys. Res. Commun. 230, 206-210.
39. Bengtsson T, Orselius K, and Wettero J (2006) Role of the actin cytoskeleton during respiratory burst in chemoattractant-stimulated neutrophils. Cell Biol. Int. 30, 154-163.
40. Glading A, Uberall F, Keyse SM, Lauffenburger DA, and Wells A (2001) Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling. J. Biol Chem. 276, 23341-23348.
41. Fincham VJ, James M, Frame MC, and Winder SJ (2000) Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J. 19, 2911-2923.
42. Ishibe, S Joly, D Liu, Z.X., and Cantley, L.G. (2004) Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell 16, 257-267.
43. Schroder K, Helmcke I, Palfi K, Krause KH, Busse R, et al. (2007) Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 27, 1736-1743.
44. Paik YH, Iwaisako K, Seki E, Inokuchi S, Schnabl B, et al. (2011) The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology 53, 1730-1741.
45. Cui W, Matsuno K, Iwata K, Ibi M, Matsumoto M, et al. (2011) NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation. Hepatology 54, 949-958.
46. Bendall JK, Cave AC, Heymes C, Gall N, and Shah AM (2002) Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 105, 293-296.
47. Johar S, Cave AC, Narayanapanicker A, Grieve DJ, and Shah AM (2006) Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase. FASEB J. 20, 1546-1548.
48. Byrne JA, Grieve DJ, Bendall JK, Li JM, Gove C, et al. (2003) Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ. Res. 93, 802-805.
49. Bondi CD, Manickam N, Lee DY, Block K, Gorin Y, et al. (2010) NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J. Am. Soc. Nephrol. 21, 93-102.
50. Zhong J, Guo D, Chen CB, Wang W, Schuster M, et al. (2011) Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension 57, 314-322.
51. Liu J, Yang F, Yang XP, Jankowski M, and Pagano PJ (2003) NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy. Arterioscler. Thromb. Vasc. Biol 23, 776-782.
52. Vendrov AE, Hakim ZS, Madamanchi NR, Rojas M, Madamanchi C, et al. (2007) Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells. Arterioscler. Thromb. Vasc. Biol 27, 2714-2721.
53. Thomas M, Gavrila D, McCormick ML, Miller FJ, Daugherty A, et al. (2006) Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation 114, 404-413.