Antihyperlipidemic effect of diosmin: A citrus flavonoid on lipid metabolism in experimental diabetic rats

Journal of Functional Foods

Volumn 5, Issue 1, 2013, Pages 484-492

  Srinivasan, Subramani ^a   Pari, Leelavinothan ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Cholesterol; Diosmin; Lipoproteins; Streptozotocin

Indexed keywords

CITRUS; RATTUS; RATTUS NORVEGICUS;

EID: 84873257181     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2012.12.004     Document Type: Article

References (56)

1. Ansar S., Koska J., Reaven P.D. Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: Focus on incretins. Cardiovascular Diabetology 2011, 10:61.
2. Arcari D.P., Porto V.B., Rodrigues E.R.V., Martins F., Lima R.J.D., Sawaya A.C.H.F., Ribeiro M.L., Carvalho P.D.O. Effect of mate tea (Ilex paraguariensis) supplementation on oxidative stress biomarkers and LDL oxidisability in normo- and hyperlipidaemic humans. Journal of Functional Foods 2011, 3:190-197.
3. Bisse E., Abragam E.C. New less temperature sensitive, microchromato graphic method for the separation and quantitation of glycosylated haemoglobin using a non cyanide buffer system. Journal of Chromatography 1999, 344:81-91.
4. Camarda L., Di Stefano V., Del Bosco S.F., Schillaci D. Antiproliferative activity of citrus juices and HPLC evaluation of their flavonoid composition. Fitoterapia 2007, 78:426-429.
5. Campanero M.A., Escolar M., Perez Garcia-Quetglas E., Sadaba B., Azanza J.R. Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2010, 51:875-881.
6. Catanzaro N.D.J.A., Suen M.T.R. Clinical laboratory indicators of cardiovascular disease risk. Alternative Medicine Review 1996, 1:185-194.
7. Dirican M., Serdar Z., Sarandol E., Gur E.S. Lecithin: Cholesterol acyltransferase activity and cholesteryl ester transfer rate in patients with diabetes mellitus. Turkish Journal of Medical Sciences 2003, 33:95-101.
8. Duckworth W., Abraira C., Moritz T., Reda D., Emanuele N., Reaven P.D., Zieve F.J., Marks J., Davis S.N., Hayward R., Warren S.R., Goldman S., McCarren M., Vitek M.E., Henderson W.G., Huang G.D. Glucose control and vascular complications in veterans with type2 diabetes. The New England Journal of Medicine 2009, 360:129-139.
9. Duncan B.D. Multiple range test for correlated and heteroscedastic means. Biometrics 1957, 13:359-364.
10. Falholt K., Falholt W., Lund B. An easy colorimetric method for routine determination of free fatty acids in plasma. Clinica Chimica Acta 1973, 46:105-111.
11. Farmer J.A. Diabetic dyslipidemia and atherosclerosis: Evidence from clinical trials. Current Diabetes Reports 2008, 8:71-77.
12. Fiske C.H., Subbarow Y. The colorimetric determination of phosphorus. The Journal of Biological Chemistry 1925, 66:375-400.
13. Folch J., Lees M., Solane S.G.H. A simple method for isolation and purification of total lipids from animal tissues. The Journal of Biological Chemistry 1957, 26:497-509.
14. Fossati P., Lorenzo P. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clinical Chemistry 1982, 28:2077-2080.
15. Garvey W.T., Kwon S., Zheng D., Shaughnessy S., Wallace P., Hutto A., Pugh K., Jenkins A.J., Klein R.L., Liao Y. Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. Diabetes 2003, 52:453-462.
16. Hanyu O., Miida T., Obayashi K., Ikarashi T., Soda S., Kaneko S., Hirayama S., Suzuki K., Nakamuraa Y., Yamatani K., Aizawa Y. Lipoprotein lipase (LPL) mass in preheparin serum reflects insulin sensitivity. Atherosclerosis 2004, 174:385-390.
17. Hitz J., Steinmetz J., Siest G. Plasma lecithin: Cholesterol acyltransferase - reference values and effects of xenobiotics. Clinica Chimica Acta 1983, 133:85-96.
18. Huang D.W., Shen S.C. Caffeic acid and cinnamic acid ameliorate glucose metabolism via modulating glycogenesis and gluconeogenesis in insulin-resistant mouse hepatocytes. Journal of Functional Foods 2012, 4:358-366.
19. Iozzo P., Turpeinen A.K., Takala T., Oikonen V., Bergman J., Grönroos T., Ferrannini E., Nuutila P., Knuuti J. Defective liver disposal of free fatty acids in patients with impaired glucose tolerance. The Journal of Clinical Endocrinology & Metabolism 2004, 89:3496-3502.
20. Jain S.K., McVie R., Meachuan Z.D., Smith T. Effect of LDL and VLDL oxidizability and hyperglycemia on blood cholesterol, phospholipid and triglyceride levels in type I diabetic patients. Atherosclerosis 2000, 149:69-73.
21. Karthikesan K., Pari L., Menon V.P. Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. Chemico Biological Interactions 2010, 188:643-650.
22. Korn E.D. Clearing factor: A heparin activated lipoprotein lipase: Isolation and characterization of enzyme from normal rats. The Journal of Biological Chemistry 1955, 215:1-26.
23. Kulkarni C.R., Joglekar M.M., Patil S.B., Arvindekar A.U. Antihyperglycemic and antihyperlipidemic effect of Santalum album in streptozotocin induced diabetic rats. Pharmaceutical Biology 2012, 50:360-365.
24. Kunnen S., Van Eck M. Lecithin:cholesterol acyltransferase: Old friend or foe in atherosclerosis?. The Journal of Lipid Research 2012, 53:1783-1799.
25. Lima V.L.M., Coelho B.B., Kennedy J.F., Owen J.S., Dolphin P.J. Lecithin: Cholesterol acyl transferase (LCAT) as a plasma glycoprotein: An overview. Carbohydrate Polymers 2004, 55:179-191.
26. Lopez-Virella M.F., Wholtmann H.J., Mayfield R.K., Loadholt C.B., Colwell J.A. Effect of metabolic control on lipid, lipoprotein, and apolipoprotein levels in 55 insulin-dependent diabetic patients: A longitudinal study. Diabetes 1983, 32:20-25.
27. Lovejoy J.C., Champagne C.M., Smith S.R., DeLany J.P., Bray G.A., Lefevre M., Denkins Y.M., Rood J.C. Relationship of dietary fat and serum cholesterol ester and phospholipid fatty acids to marker of insulin resistance in men and women with a range of glucose tolerance. Metabolism 2001, 50:86-92.
28. Marounek M., Volek Z., Synytsya A., Copikova J. Effect of pectin and amidated pectin on cholesterol homeostasis and cecal metabolism in rats fed a high-cholesterol diet. Physiological Research 2007, 56:433-442.
29. Masiello P., Broca C., Gross R., Roye M., Manteghetti M., Hillaire-Buys M., Novelli D., Ribes G. Experimental NIDDM: Development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes 1998, 47:224-229.
30. McGarry J.D. Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002, 51:7-18.
31. Ness G.C., Chambers C.M. Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: The concept of cholesterol buffering capacity. Proceedings of the Society for Experimental Biology and Medicine 2000, 224:8-19.
32. Nobecourt E., Davies M.J., Brown B.E., Curtiss L.K., Bonnet D.J., Charlton F., Januszewski A.S., Jenkins A.J., Barter B.J., Rye K.A. The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin:cholesterol acyltransferase. Diabetologia 2007, 50:643-653.
33. Pandhare R.B., Sangameswaran B., Mohite P.B., Khanage S.G. Anti-hyperglycaemic and lipid lowering potential of Adenanthera pavonina Linn. in streptozotocin induced diabetic rats. Oriental Pharmacy and Experimental Medicine 2012, 12:197-203.
34. Pari L., Srinivasan S. Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. Biomedicine & Pharmacotherapy 2010, 64:477-481.
35. Pari L., Srinivasan S. Preventive effect of diosmin, a bioflavonoid, on glycoprotein changes in streptozotocin-nicotinamide-induced type 2 diabetic rats. International Journal of Pharmaceutical Sciences and Research 2010, 10:89-95.
36. Philipp B., Shapiro D.J. Improved methods for the assay and activation of 3-hydroxy-3-methyl glutaryl coenzyme A reductase. The Journal of Lipid Research 1970, 20:588-593.
37. Prabakaran D., Ashokkumar N. Antihyperglycemic effect of esculetin modulated carbohydrate metabolic enzymes activities in streptozotocin induced diabetic rats. Journal of Functional Foods 2012, 4:963-971.
38. Pruneta-Deloche V., Sassolas A., Dallinga-Thie G.M., Berthezene F., Ponsin G., Moulin P. Alteration in lipoprotein lipase activity bound to triglyceride-rich lipoproteins in the postprandial state in type 2 diabetes. The Journal of Lipid Research 2004, 45:859-865.
39. Sambandam N., Abrahani M.A., Craig S., Al-Atar O., Jeon E., Rodrigues B. Metabolism of VLDL is increased in streptozotocin induced diabetic rat hearts. American Journal of Physiology Heart and Circulatory Physiology 2000, 278:1874-1882.
40. Savel J., Lafitte M., Pucheu Y., Pradeau V., Tabarin A., Couffinhal T. Very low levels of HDL cholesterol and atherosclerosis, a variable relationship - a review of LCAT deficiency. Journal of Vascular Health and Risk Management 2012, 8:357-361.
41. Schneider I., Kressel G., Meyer A., Krings U., Berger R.G., Hahn A. Lipid lowering effects of oyster mushroom (Pleurotus ostreatus) in humans. Journal of Functional Foods 2011, 3:17-24.
42. Shaw J.E., Sicree R.A., Zimmer P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice 2010, 87:4-14.
43. Shepherd J. Does statin mono therapy address the multiple lipid abnormalities in type-2 diabetes. Atherosclerosis Supplements 2005, 6:15-19.
44. Singh I.M., Shishehbor M.H., Ansell B.J. High-density lipoprotein as a therapeutic target: A systematic review. The Journal of the American Medical Association 2007, 298:786-798.
45. Solano M.P., Goldberg R.B. Management of dyslipidemia in diabetes. Cardiology in Review 2006, 14:125-135.
46. Srinivasan S., Pari L. Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats. Chemico Biological Interactions 2012, 195:43-51.
47. Stirban O.A., Tschoepe D. Cardiovascular complications in diabetes: Targets and interventions. Diabetes Care 2008, 31:215-221.
48. Taleb-Senouci D., Lacaille-Dubois M.A., Bouchenak M. Jugaiva aqueous extract improves reverse cholesterol transport in streptozotocin-induced diabetic rat. Journal of Pharmacy and Pharmacology 2012, 64:1188-1194.
49. Thilakarathna S.H., Wang Y., Vasantha Rupasinghe H.P., Ghanam K. Apple peel flavonoid-and triterpene-enriched extracts differentially affect cholesterol homeostasis in hamsters. Journal of Functional Foods 2012, 4:963-971.
50. Trinder P. Determination of glucose in blood using glucose oxidase with analternative oxygen acceptor. Annals of Clinical Biochemistry 1969, 6:24-27.
51. Tripoli E., La Guardia M., Giammanco S., Di Majo D., Giammanco M. Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review. Food Chemistry 2007, 104:466-479.
52. Unlu A., Sucu N., Tamer L., Coskun B., Yucebilgiç G., Ercan B., Gul A., Dikmengil M., Atik U. Effects of Daflon on oxidative stress induced by hindlimb ischemia/reperfusion. Pharmacological Research 2003, 48:11.
53. Wong H., Schotz M.C. The lipase gene family. The Journal of Lipid Research 2002, 43:993-999.
54. Ye J.M., Frangioudakis G., Iglesias M.A., Furler S.M., Ellis B., Dzamko N., Cooney G.J., Kraegen E.W. Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: Role of the liver. Endocrinology 2002, 143:4527-4535.
55. Zilversmit B.B., Davis A.K. Micro determination of plasma phospholipids by richloroacetic acid precipitation. Journal of Laboratory and Clinical Medicine 1950, 35:155-160.
56. Zlatkis A., Zak B., Boyle G.J. A simple method for determination of serum cholesterol. Journal of Clinical Medicine Research 1953, 41:486-492.