Ajuga iva aqueous extract improves reverse cholesterol transport in streptozotocin-induced diabetic rat

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 8, 2012, Pages 1188-1194

  Taleb Senouci, Douja ^a   Lacaille Dubois, Marie A ^b   Bouchenak, Malika ^a  

^a UNIVERSITY OF ORAN   (Algeria)

^b UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

Ajuga iva; Diabetes; HDL; Lecithin: cholesterol acyltransferase; Rat

Indexed keywords

AJUGA IVA EXTRACT; APOLIPOPROTEIN; APOLIPOPROTEIN A1; CASEIN; CHOLESTEROL; CHOLESTEROL ESTER; CREATININE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

AJUGA; AJUGA IVA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIATHEROGENIC EFFECT; AQUEOUS SOLUTION; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DIET SUPPLEMENTATION; DRUG ACTIVITY; DYSLIPIDEMIA; ENZYME ACTIVITY; HEMOGLOBIN BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MALE; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; RAT; STREPTOZOCIN DIABETES; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; UREA BLOOD LEVEL;

AJUGA; ANIMALS; APOLIPOPROTEIN A-I; BIOLOGICAL TRANSPORT; CHOLESTEROL; CHOLESTEROL ESTERS; CHOLESTEROL, HDL; DIABETES MELLITUS, EXPERIMENTAL; DIETARY SUPPLEMENTS; LECITHINS; MALE; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PHOSPHOLIPIDS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; TRIGLYCERIDES;

EID: 84863724829     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01501.x     Document Type: Article

References (49)

1. Jonas A,. Lecithin cholesterol acyltransferase. Biochim Biophys Acta 2000; 1529: 245-246.
2. Jin W, et al,. Lipases and HDL metabolism. Trends Endocrinol Metab 2002; 13: 174-178. (Pubitemid 36733992)
3. Tan KC,. Reverse cholesterol transport in type 2 diabetes mellitus. Diabetes Obes Metab 2009; 11: 534-543.
4. Ghanei A, et al,. Lecithin cholesterol acyltransferase activity is decreased in type 2 diabetes mellitus. Acta Med Iran 2007; 45: 481-486. (Pubitemid 351488794)
5. Vergès B,. Lipid modification in type 2 diabetes: the role of LDL and HDL. Fundam Clin Pharmacol 2009; 23: 681-685.
6. Vergès B,. Lipid disorders in type 1 diabetes. Diabetes Metab 2009; 35: 353-360.
7. Dirican M, et al,. Lecithin: cholesterol acyltransferase activity and cholesteryl ester transfer rate in patients with diabetes mellitus. Turk J Med Sci 2003; 33: 95-101. (Pubitemid 36604408)
8. Nobecourt E, et al,. The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase. Diabetologia 2007; 50: 643-653. (Pubitemid 46215509)
9. Guan JZ, et al,. HMG CoA reductase inhibitor, simvastatin improves reverse cholesterol transport in type 2 diabetic patients with hyperlipidemia. J Atheroscler Thromb 2008; 15: 20-25.
10. Bnouham M, et al,. Medicinal plants used in the treatment of diabetes in Morocco. Int J Diabetes Metab 2002; 10: 33-50. (Pubitemid 36437490)
11. El-Hilaly J, et al,. Ethnobotanical studies and economic evaluation of medicinal plants in Taounate province (northern Morocco). J Ethnopharmacol 2003; 86: 149-158. (Pubitemid 36542869)
12. El-Hilaly J, Lyoussi B,. Hypoglycaemic effect of the lyophilised aqueous extract of Ajuga iva in normal and streptozotocin diabetic rats. J Ethnopharmacol 2002; 80: 109-113. (Pubitemid 34462196)
13. El-Hilaly J, et al,. Hypolipidemic effects of acute and sub-chronic administration of an aqueous extract of Ajuga iva L. whole plant in normal and diabetic rats. J Ethnopharmacol 2006; 105: 441-448.
14. El-Hilaly J, et al,. Acute hypoglycemic, hypocholesterolemic and hypotriglyceridemic effects of continuous intravenous infusion of a lyophilised aqueous extract of Ajuga iva L. Schreber whole plant in streptozotocin-induced diabetic rats. Pak J Pharm Sci 2007; 20: 261-268.
15. Taleb-Senouci D, et al,. Antioxidant effect of Ajuga iva aqueous extract in streptozotocin-induced diabetic rats. Phytomedicine 2009; 16: 623-631.
16. Wagner H, Bladt S,. Plant Drug Analysis: A Thin Layer Chromatography Atlas, 2nd edn. Berlin, Heidelberg: Springer-Verlag, 1996.
17. Ghedira K, et al,. Study of the traditional Pharmacopeia of Tunisia. Plant Méd Phytothér 1991; 25: 100-111.
18. Council of European Communities. Council instructions about the protection of living animals used in scientific investigations. 1987 Official J. L358 of 18-12-1986; Corrigendum Official J. L117 of 05-05-1987.
19. Glomset JA, Wright JL,. Some properties of cholesterol esterifying enzyme in human plasma. Biochim Biophys Acta 1964; 89: 266-271.
20. Knipping G,. Isolation and properties of porcine lecithin: cholesterol acyltransferase. Eur J Biochem 1986; 154: 289-294.
21. Burstein M, et al,. Rapid method for the isolation of two purified subfractions of high density lipoproteins by differential dextran sulphate-magnesium chloride precipitation. Biochimie 1989; 71: 741-746. (Pubitemid 19166380)
22. Havel RJ, et al,. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 1955; 34: 1345-1353.
23. Lowry OH, et al,. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265-275.
24. Bavarva JH, Narasimhacharya AVRL,. Leucas cephalotes regulates carbohydrate and lipid metabolism and improves antioxidant status in IDDM and NIDDM rats. J Ethnopharmacol 2010; 127: 98-102.
25. Prakasam A, et al,. Antiperoxidative and antioxidant effects of Casearia esculenta root extract in streptozotocin-induced diabetic rats. Yale J Biol Med 2005; 78: 15-23.
26. Latha M, et al,. Scoparia dulcis, a traditional antidiabetic plant, protects against streptozotocin induced oxidative stress and apoptosis in vitro and in vivo. J Biochem Mol Toxicol 2004; 18: 261-272. (Pubitemid 39463519)
27. Nakhjavani M, et al,. HbA1c negatively correlates with LCAT activity in type 2 diabetes. Diabetes Res Clin Pract 2008; 81: 38-41.
28. Khan HA, et al,. Association between glycaemic control and serum lipids profile in type 2 diabetic patients: HbA1c predicts dyslipidaemia. Clin Exp Med 2007; 7: 24-29. (Pubitemid 46475007)
29. +)-ATPase activity reduction in high glucose-treated human erythrocytes. Free Radic Biol Med 2001; 30: 232-237. (Pubitemid 32126443)
30. Yue KKM, et al,. Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats. Life Sci 2003; 73: 2557-2570. (Pubitemid 37088206)
31. Bijlani RL, et al,. A brief but comprehensive lifestyle education program based on yoga reduces risk factors for cardiovascular disease and diabetes mellitus. J Altern Complement Med 2005; 11: 267-274. (Pubitemid 40647161)
32. Zennaki S, et al,. Globularia alypum L. lyophilized methanolic extract decreases hyperglycemia and improves antioxidant status in various tissues of streptozotocin-induced diabetic rats. J Complement Integr Med 2009; 6: 1-13.
33. De Sereday MS, et al,. Prevalence of diabetes, obesity, hypertension and hyperlipidemia in the central area of Argentina. Diabetes Metab 2004; 30: 335-339. (Pubitemid 39280232)
34. Tunali S, Yanardag R,. Effect of vanadyl sulfate on the status of lipid parameters and on stomach and spleen tissues of streptozotocin-induced diabetic rats. Pharmacol Res 2006; 53: 271-277. (Pubitemid 43247540)
35. Tan BK, et al,. Anti-diabetic activity of the semi-purified fractions of Averrhoa bilimbi in high fat diet fed streptozotocin-induced diabetic rats. Life Sci 2005; 76: 2827-2839. (Pubitemid 40460328)
36. Bhandari U, et al,. Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol 2005; 97: 227-230. (Pubitemid 40222022)
37. Kumar G, Murugesan AG,. Hypolipidemic activity of Helicteres isora L. bark extracts in streptozotocin induced diabetic rats. J Ethnopharmacol 2008; 116: 161-166.
38. Camps F, et al,. New clerodane diterpenoids from Ajuga iva (Labiatae). Chem Lett 1982; 7: 1053-1056.
39. Bondi ML, et al,. Occurrence of the antifeedant 14,15-dihydroajugapitin in the aerial parts of Ajuga iva from Algeria. Biochem Syst Ecol 2000; 28: 1023-1025.
40. Wessner M, et al,. Ecdysteroids from Ajuga iva. Phytochemistry 1992; 31: 3785-3788.
41. Syrov VN, et al,. Hypolipidemic and antiatherosclerotic properties of phytoecdysteroids. Dok Akad Nauk USSR 1983; 9: 44-45.
42. Wagner H, Lacaille-Dubois MA,. Recent pharmacological results on bioflavonoids. In:, Antus S, et al., ed. Flavonoids and Bioflavonoids. Budapest: Akademiai Kiado, 1995: 53-72.
43. Xie W, et al,. The effects of Ananas comosus L. leaves on diabetic-dyslipidemic rats induced by alloxan and a high-fat/high-cholesterol diet. Am J Chin Med 2005; 33: 95-105. (Pubitemid 40468307)
44. Van der Steeg WA, et al,. Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-norfolk. Ann Intern Med 2007; 146: 640-648. (Pubitemid 351650519)
45. Lee JY, Parks JS,. ATP-binding cassette transporter AI and its role in HDL formation. Curr Opin Lipidol 2005; 16: 19-25. (Pubitemid 40333362)
46. Walldius G, et al,. High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 2001; 358: 2026-2033. (Pubitemid 34084825)
47. Von EA, et al,. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscler Thromb Vasc Biol 2001; 21: 13-27.
48. Quintão EC, et al,. Reverse cholesterol transport in diabetes mellitus. Diabetes Metab Res Rev 2000; 16: 237-250. (Pubitemid 30611784)
49. Rousset X, et al,. Lecithin: cholesterol acyltransferase from biochemistry to role in cardiovascular disease. Curr Opin Endocrinol Diabetes Obes 2009; 16: 163-171.