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Volumn 67, Issue 1, 2013, Pages 31-38

The effect of purmorphamine and sirolimus on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Author keywords

Human mesenchymal stem cells; Osteogenic differentiation; Purmorphamine; Sirolimus; Small molecules

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; MORPHINE DERIVATIVE; OSTEOCALCIN; PURMORPHAMINE; RAPAMYCIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 84873248808     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2012.10.004     Document Type: Article
Times cited : (25)

References (41)
  • 1
    • 0036524009 scopus 로고    scopus 로고
    • Persistent iliac crest donor site pain: independent outcome assessment
    • Heary R.F., Schlenk R.P., Sacchieri T.A., Barone D. Persistent iliac crest donor site pain: independent outcome assessment. Neurosurgery 2002, 50:510-516.
    • (2002) Neurosurgery , vol.50 , pp. 510-516
    • Heary, R.F.1    Schlenk, R.P.2    Sacchieri, T.A.3    Barone, D.4
  • 2
    • 10244219994 scopus 로고    scopus 로고
    • Hospital-based allogenic bonebank - 10-year experience
    • Hou C.H., Yang R., Hou S.M. Hospital-based allogenic bonebank - 10-year experience. J Hosp Infect 2005, 59:41-45.
    • (2005) J Hosp Infect , vol.59 , pp. 41-45
    • Hou, C.H.1    Yang, R.2    Hou, S.M.3
  • 3
    • 34250820410 scopus 로고    scopus 로고
    • Xenotransplantation: current status and a perspective on the future
    • Yang Y.G., Sykes M. Xenotransplantation: current status and a perspective on the future. Nat Rev Immunol 2007, 7:519-531.
    • (2007) Nat Rev Immunol , vol.7 , pp. 519-531
    • Yang, Y.G.1    Sykes, M.2
  • 6
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P.D., Matteucci P., et al. Human bone marrow stromal cells suppress T lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002, 99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6
  • 7
    • 33947593728 scopus 로고    scopus 로고
    • Mesenchymalstem cells stimulate antibody secretion in human B cells
    • Rasmusson I., Le Blanc K., Sundberg B., Ringdén O. Mesenchymalstem cells stimulate antibody secretion in human B cells. Scand J Immunol 2007, 65:336-343.
    • (2007) Scand J Immunol , vol.65 , pp. 336-343
    • Rasmusson, I.1    Le Blanc, K.2    Sundberg, B.3    Ringdén, O.4
  • 8
    • 0016214539 scopus 로고
    • Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method
    • Friedenstein A.J., Deriglasova U.F., Kulagina N.N., Panasuk A.F., Rudakowa S.F., Ruadkow I.A. Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method. Exp Hematol 1974, 2:83-92.
    • (1974) Exp Hematol , vol.2 , pp. 83-92
    • Friedenstein, A.J.1    Deriglasova, U.F.2    Kulagina, N.N.3    Panasuk, A.F.4    Rudakowa, S.F.5    Ruadkow, I.A.6
  • 9
    • 79955137985 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients
    • Davatchi F., Abdollahi B.S., Mohyeddin M., Shahram F., Nikbin B. Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients. Int J Rheum Dis 2011, 14:211-215.
    • (2011) Int J Rheum Dis , vol.14 , pp. 211-215
    • Davatchi, F.1    Abdollahi, B.S.2    Mohyeddin, M.3    Shahram, F.4    Nikbin, B.5
  • 11
    • 82655170631 scopus 로고    scopus 로고
    • Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells
    • Zhao D., Cui D., Wang B., Tian F., Guo L., Yang L., et al. Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells. Bone 2012, 50:325-330.
    • (2012) Bone , vol.50 , pp. 325-330
    • Zhao, D.1    Cui, D.2    Wang, B.3    Tian, F.4    Guo, L.5    Yang, L.6
  • 12
    • 69249208415 scopus 로고    scopus 로고
    • Comparative materials differences revealed in engineered bone as a function of cell-specifi c differentiation
    • Gentleman E., Swain R.J., Evans N.D., Boonrungsiman S., Jell G., Ball M.D. Comparative materials differences revealed in engineered bone as a function of cell-specifi c differentiation. Nat Mater 2009, 8:763-770.
    • (2009) Nat Mater , vol.8 , pp. 763-770
    • Gentleman, E.1    Swain, R.J.2    Evans, N.D.3    Boonrungsiman, S.4    Jell, G.5    Ball, M.D.6
  • 13
    • 0028955719 scopus 로고
    • Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: induction of a transition from nonadherent to adherent osteoblast precursors
    • Scutt A., Bertram P. Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: induction of a transition from nonadherent to adherent osteoblast precursors. J Bone Miner Res 1995, 10:474-487.
    • (1995) J Bone Miner Res , vol.10 , pp. 474-487
    • Scutt, A.1    Bertram, P.2
  • 16
    • 0034949211 scopus 로고    scopus 로고
    • Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation
    • Spinella-Jaegle S., Rawadi G., Kawai S., Gallea S., Faucheu C., Mollat P., et al. Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation. J Cell Sci 2001, 114:2085-2094.
    • (2001) J Cell Sci , vol.114 , pp. 2085-2094
    • Spinella-Jaegle, S.1    Rawadi, G.2    Kawai, S.3    Gallea, S.4    Faucheu, C.5    Mollat, P.6
  • 17
    • 77956079673 scopus 로고    scopus 로고
    • Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells
    • James A.W., Leucht P., Levi B., Carre A.L., Xu Y., Helms J.A., et al. Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells. Tissue Eng Part A 2010, 16:2605-2616.
    • (2010) Tissue Eng Part A , vol.16 , pp. 2605-2616
    • James, A.W.1    Leucht, P.2    Levi, B.3    Carre, A.L.4    Xu, Y.5    Helms, J.A.6
  • 18
    • 82455186157 scopus 로고    scopus 로고
    • Exploring the chemical space of known and unknown organic small molecules at www.gdb.unibe.ch
    • Reymond J.L., Bluma L.C., Deursen R. Exploring the chemical space of known and unknown organic small molecules at www.gdb.unibe.ch. Chimia 2011, 65:863-867.
    • (2011) Chimia , vol.65 , pp. 863-867
    • Reymond, J.L.1    Bluma, L.C.2    Deursen, R.3
  • 19
    • 11144341956 scopus 로고    scopus 로고
    • Chemical space and biology
    • Dobson C.M. Chemical space and biology. Nature 2004, 432:824-828.
    • (2004) Nature , vol.432 , pp. 824-828
    • Dobson, C.M.1
  • 20
    • 21144440283 scopus 로고    scopus 로고
    • Chemical genetics to chemical genomics: small molecules offer big insights
    • Spring D.R. Chemical genetics to chemical genomics: small molecules offer big insights. Chem Soc Rev 2011, 34:472-482.
    • (2011) Chem Soc Rev , vol.34 , pp. 472-482
    • Spring, D.R.1
  • 21
    • 0037065356 scopus 로고    scopus 로고
    • Small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cell
    • Wu X., Ding S., Gray N.S., Schultz P.G. Small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cell. J Am Chem Soc 2002, 124:14520-14521.
    • (2002) J Am Chem Soc , vol.124 , pp. 14520-14521
    • Wu, X.1    Ding, S.2    Gray, N.S.3    Schultz, P.G.4
  • 22
    • 4644250693 scopus 로고    scopus 로고
    • Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway
    • Wu X., Walker J., Zhang J., Ding S., Schultz P.G. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem Biol 2004, 11:1229-1238.
    • (2004) Chem Biol , vol.11 , pp. 1229-1238
    • Wu, X.1    Walker, J.2    Zhang, J.3    Ding, S.4    Schultz, P.G.5
  • 23
    • 84055177068 scopus 로고    scopus 로고
    • Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells
    • Oliveira F.S., Bellesini L.S., da Silva Herrero C.F., Beloti M.M., Rosa A. Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells. J Cell Biochem 2012, 113:204-208.
    • (2012) J Cell Biochem , vol.113 , pp. 204-208
    • Oliveira, F.S.1    Bellesini, L.S.2    da Silva Herrero, C.F.3    Beloti, M.M.4    Rosa, A.5
  • 24
    • 65249135916 scopus 로고    scopus 로고
    • Activation of Hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells
    • Plaisant M., Fontaine C., Cousin W., Rochet N., Dani C., Peraldi P. Activation of Hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells. Stem Cells 2009, 27:703-713.
    • (2009) Stem Cells , vol.27 , pp. 703-713
    • Plaisant, M.1    Fontaine, C.2    Cousin, W.3    Rochet, N.4    Dani, C.5    Peraldi, P.6
  • 25
    • 2442635905 scopus 로고    scopus 로고
    • Pro- and anti- cancer effects of immunosuppressive agents used in organ transplantation
    • Guba M., Graeb C., Jauch K.W., Geissler E. Pro- and anti- cancer effects of immunosuppressive agents used in organ transplantation. Transplantation 2004, 77:1777-1782.
    • (2004) Transplantation , vol.77 , pp. 1777-1782
    • Guba, M.1    Graeb, C.2    Jauch, K.W.3    Geissler, E.4
  • 26
    • 77950603770 scopus 로고    scopus 로고
    • Rapamycin promotes the osteobastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway
    • Lee K.W., Yook J.Y., Son M.Y., Kim M.J., Koo D.B., Han Y.M., et al. Rapamycin promotes the osteobastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. Stem Cells Dev 2010, 19:557-568.
    • (2010) Stem Cells Dev , vol.19 , pp. 557-568
    • Lee, K.W.1    Yook, J.Y.2    Son, M.Y.3    Kim, M.J.4    Koo, D.B.5    Han, Y.M.6
  • 27
    • 33846513349 scopus 로고    scopus 로고
    • Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells
    • Isomoto S., Mattori K., Ohgushi H., Nakajima H., Tanaka Y. Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells. J Orthop Sci 2007, 12:83-88.
    • (2007) J Orthop Sci , vol.12 , pp. 83-88
    • Isomoto, S.1    Mattori, K.2    Ohgushi, H.3    Nakajima, H.4    Tanaka, Y.5
  • 28
    • 38649110155 scopus 로고    scopus 로고
    • Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells
    • Singha U.K., Jiang Y., Yu S., Luo M., Lu Y., Zhang J., et al. Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells. J Cell Biochem 2008, 103:434-446.
    • (2008) J Cell Biochem , vol.103 , pp. 434-446
    • Singha, U.K.1    Jiang, Y.2    Yu, S.3    Luo, M.4    Lu, Y.5    Zhang, J.6
  • 29
    • 80052430364 scopus 로고    scopus 로고
    • Discovering small molecules to control stem cell fate
    • Andrews P.D. Discovering small molecules to control stem cell fate. Future Med Chem 2011, 3:1539-1549.
    • (2011) Future Med Chem , vol.3 , pp. 1539-1549
    • Andrews, P.D.1
  • 30
    • 63049094292 scopus 로고    scopus 로고
    • Bone growth during rapamycin therapy in young rats
    • Sanchez C.P., He Y.Z. Bone growth during rapamycin therapy in young rats. BMC Pediatr 2008, 13:3-9.
    • (2008) BMC Pediatr , vol.13 , pp. 3-9
    • Sanchez, C.P.1    He, Y.Z.2
  • 31
    • 0032504527 scopus 로고    scopus 로고
    • Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells
    • Ogawa T., Tokuda M., Tomizawa K., Matsui H., Konishi R. Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. Biochem Biophys Res Commun 1998, 249:226-230.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 226-230
    • Ogawa, T.1    Tokuda, M.2    Tomizawa, K.3    Matsui, H.4    Konishi, R.5
  • 32
    • 23744442102 scopus 로고    scopus 로고
    • Purmorphamine enhances ostegenic activity of human osteoblasts derived from bone marrow mesenchymal cells
    • Beloti M.M., Bellesini L.S., Rosa A.L. Purmorphamine enhances ostegenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Cell Biol Int 2005, 29:537-541.
    • (2005) Cell Biol Int , vol.29 , pp. 537-541
    • Beloti, M.M.1    Bellesini, L.S.2    Rosa, A.L.3
  • 33
    • 0018761728 scopus 로고
    • Effect of epidermal growth factor on bone formation in vitro
    • Canalis E., Raisz L.G. Effect of epidermal growth factor on bone formation in vitro. Endocrinology 1979, 104:862-869.
    • (1979) Endocrinology , vol.104 , pp. 862-869
    • Canalis, E.1    Raisz, L.G.2
  • 34
    • 67349168122 scopus 로고    scopus 로고
    • In vitro osteogenesis assays: influence of the primary cell source on alkaline phosphatase activity and mineralization
    • Hoemann C.D., El-Gabalawy H., McKee M.D. In vitro osteogenesis assays: influence of the primary cell source on alkaline phosphatase activity and mineralization. Pathol Biol 2009, 57:318-323.
    • (2009) Pathol Biol , vol.57 , pp. 318-323
    • Hoemann, C.D.1    El-Gabalawy, H.2    McKee, M.D.3
  • 35
    • 0025845372 scopus 로고
    • Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate
    • Bellows C.G., Aubin J.E., Heersche J.N. Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate. Bone Miner 1991, 14:27-40.
    • (1991) Bone Miner , vol.14 , pp. 27-40
    • Bellows, C.G.1    Aubin, J.E.2    Heersche, J.N.3
  • 36
    • 0025110930 scopus 로고
    • Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization
    • Weinreb M., Shinar D., Rodan G.A. Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization. J Bone Miner Res 1990, 5:831-842.
    • (1990) J Bone Miner Res , vol.5 , pp. 831-842
    • Weinreb, M.1    Shinar, D.2    Rodan, G.A.3
  • 37
    • 0027267003 scopus 로고
    • Expression of Osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone
    • Merry K., Dodds R., Littlewood A., Gowen M. Expression of Osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone. J Cell Sci 1993, 104:1013-1020.
    • (1993) J Cell Sci , vol.104 , pp. 1013-1020
    • Merry, K.1    Dodds, R.2    Littlewood, A.3    Gowen, M.4
  • 38
    • 56649122122 scopus 로고    scopus 로고
    • Osteopontin might be involved in bone remodelling rather than in inflammation in ankylosing spondylitis
    • Choi S.T., Kim J.H., Kang E.J., Lee S.W., Park M.C., Park Y.B., et al. Osteopontin might be involved in bone remodelling rather than in inflammation in ankylosing spondylitis. Rheumatology 2008, 47:1775-1779.
    • (2008) Rheumatology , vol.47 , pp. 1775-1779
    • Choi, S.T.1    Kim, J.H.2    Kang, E.J.3    Lee, S.W.4    Park, M.C.5    Park, Y.B.6
  • 39
    • 84873245474 scopus 로고
    • Development expression of bone sialoprotein mRNA in rat mineralized connective tissues
    • Chen J., Shapiro H.S., Sodek J. Development expression of bone sialoprotein mRNA in rat mineralized connective tissues. J Bone Miner Res 1992, 6:7987-7997.
    • (1992) J Bone Miner Res , vol.6 , pp. 7987-7997
    • Chen, J.1    Shapiro, H.S.2    Sodek, J.3
  • 40
    • 0027136162 scopus 로고
    • Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta
    • Ikeda T., Shirasawa T., Esaki Y., Yoshiki S. Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 1993, 92:2814-2820.
    • (1993) J Clin Invest , vol.92 , pp. 2814-2820
    • Ikeda, T.1    Shirasawa, T.2    Esaki, Y.3    Yoshiki, S.4
  • 41
    • 84871601011 scopus 로고    scopus 로고
    • Quantitative study of alkaline phosphatase and osteocalcin in the process of new bone
    • Chang X., Hou Z.M., Yasuaki S., Tomoo T., Akira Y. Quantitative study of alkaline phosphatase and osteocalcin in the process of new bone. Hua Xi Kou Qiang Yi Xue Za Zhi 2005, 23:424-426.
    • (2005) Hua Xi Kou Qiang Yi Xue Za Zhi , vol.23 , pp. 424-426
    • Chang, X.1    Hou, Z.M.2    Yasuaki, S.3    Tomoo, T.4    Akira, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.