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Chemical Society Reviews

Volumn 34, Issue 6, 2005, Pages 472-482

Chemical genetics to chemical genomics: Small molecules offer big insights

(1) Spring, David R a

a UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA;

CELL MEMBRANE PERMEABILITY; CHEMICAL GENETICS; CHEMICAL GENOMICS; CYTOSKELETON; GENETIC MANIPULATION; GENETIC TRANSCRIPTION; GENOMICS; KNOCKOUT GENE; MOLECULAR SIZE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 21144440283 PISSN: 03060012 EISSN: 14604744 Source Type: Journal
DOI: 10.1039/b312875j Document Type: Article

Times cited : (239)

References (38)

1
- 0031710509
- S. L. Schreiber, Bioorg. Med. Chem. 1998, 6, 1127-1152
- (1998) Bioorg. Med. Chem , vol.6 , pp. 1127-1152
- Schreiber, S.L.¹

2
- 0034920256
- G. MacBeath, Genome Biol. 2001, 2, 2005.1-2005.6
- (2001) Genome Biol. , vol.2 , pp. 1-2005
- Macbeath, G.¹

3
- 0344515366
- D. R. Spring, Org. Biomol. Chem. 2003, 1, 3867-3870
- (2003) Org. Biomol. Chem , vol.1 , pp. 3867-3870
- Spring, D.R.¹

4
- 0035342083
- C. O'Donovan, R. Apweiler, A. Bairoch, Trends Biotechnol. 2001, 19, 178-181
- (2001) Trends Biotechnol. , vol.19 , pp. 178-181
- O'donovan, C.¹ Apweiler, R.² Bairoch, A.³

5
- 3042799070
- M. D. Burke, S. L. Schreiber, Angew. Chem. Int. Ed. 2004, 43, 46-58
- (2004) Angew. Chem. Int. Ed , vol.43 , pp. 46-58
- Burke, M.D.¹ Schreiber, S.L.²

6
- 85052960740
- Small Molecule Screening on Chemical Microarrays
- H.-J. Böhm and G. Schneider, 2003, Wiley-VCH, Weinheim, and references therein
- G. Metz, H. Ottleben and D. Vetter, “Small Molecule Screening on Chemical Microarrays”, in Protein-Ligand Interactions. From Molecular Recognition to Drug Design, Ed. H.-J. Böhm and G. Schneider, 2003, Wiley-VCH, Weinheim, pp. 213–236; and references therein
- Protein-Ligand Interactions. From Molecular Recognition to Drug Design , pp. 213-236
- Metz, G.¹ Ottleben, H.² Vetter, D.³

7
- 0037061492
- F. G. Kuruvilla, A. F. Shamji, S. M. Sternson, P. J. Hergenrother, S. L. Schreiber, Nature, 2002, 416, 653-657
- (2002) Nature , vol.416 , pp. 653-657
- Kuruvilla, F.G.¹ Shamji, A.F.² Sternson, S.M.³ Hergenrother, P.J.⁴ Schreiber, S.L.⁵

8
- 0034331004
- B. R. Stockwell, Nat. Rev. Genet. 2000, 1, 116-125
- (2000) Nat. Rev. Genet. , vol.1 , pp. 116-125
- Stockwell, B.R.¹

9
- 0036669959
- G. E. Ward, K. L. Carey, N. J. Westwood, Cellul. Microbiol. 2002, 4, 471-482
- (2002) Cellul. Microbiol. , vol.4 , pp. 471-482
- Ward, G.E.¹ Carey, K.L.² Westwood, N.J.³

10
- 0033615357
- T. U. Mayer, T. M. Kapoor, S. J. Haggarty, R. W. King, S. L. Schreiber, T. J. Mitchison, Science, 1999, 286, 971-974
- (1999) Science , vol.286 , pp. 971-974
- Mayer, T.U.¹ Kapoor, T.M.² Haggarty, S.J.³ King, R.W.⁴ Schreiber, S.L.⁵ Mitchison, T.J.⁶

11
- 0347473810
- A. B. Parsons, R. L. Brost, H. Ding, Z. Li, C. Zhang, B. Sheikh, G. W. Brown, P. M. Kane, T. R. Hughes, C. Boone, Nat. Biotechnol. 2004, 22, 62-69
- (2004) Nat. Biotechnol. , vol.22 , pp. 62-69
- Parsons, A.B.¹ Brost, R.L.² Ding, H.³ Li, Z.⁴ Zhang, C.⁵ Sheikh, B.⁶ Brown, G.W.⁷ Kane, P.M.⁸ Hughes, T.R.⁹ Boone, C.¹⁰

12
- 0034306450
- S. P. Davies, H. Reddy, M. Caivano, P. Cohen, Biochem. J. 2000, 351, 95-105
- (2000) Biochem. J. , vol.351 , pp. 95-105
- Davies, S.P.¹ Reddy, H.² Caivano, M.³ Cohen, P.⁴

13
- 0037416141
- S. L. Schreiber, Chem. Eng. News, 2003, 81, 51-61
- (2003) Chem. Eng. News , vol.81 , pp. 51-61
- Schreiber, S.L.¹

14
- 0033178766
- C. M. Crews, U. Splittgerber, Trends Biochem. Sci. 1999, 24, 317-320
- (1999) Trends Biochem. Sci. , vol.24 , pp. 317-320
- Crews, C.M.¹ Splittgerber, U.²

15
- 0034332931
- B. R. Stockwell, Trends Biotechnol. 2000, 18, 449-455
- (2000) Trends Biotechnol. , vol.18 , pp. 449-455
- Stockwell, B.R.¹

16
- 0037305949
- R. S. Lokey, Curr. Opin. Chem. Biol. 2003, 7, 91-96
- (2003) Curr. Opin. Chem. Biol , vol.7 , pp. 91-96
- Lokey, R.S.¹

17
- 4544334518
- S. M. Khersonsky, Y.-T. Chang, ChemBioChem, 2004, 5, 903-908
- (2004) Chembiochem , vol.5 , pp. 903-908
- Khersonsky, S.M.¹ Chang, Y.-T.²

18
- 0036532116
- K. M. Specht, K. M. Shokat, Curr. Opin. Cell Biol. 2002, 14, 155-159
- (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 155-159
- Specht, K.M.¹ Shokat, K.M.²

19
- 0035312350
- A. C. Bishop, O. Buzko, K. M. Shokat, Trends Cell Biol. 2001, 11, 167-172
- (2001) Trends Cell Biol. , vol.11 , pp. 167-172
- Bishop, A.C.¹ Buzko, O.² Shokat, K.M.³

20
- 0035415869
- P. J. Alaimo, M. A. Shogren-Knaak, K. M. Shokat, Curr. Opin. Chem. Biol. 2001, 5, 360-367
- (2001) Curr. Opin. Chem. Biol. , vol.5 , pp. 360-367
- Alaimo, P.J.¹ Shogren-Knaak, M.A.² Shokat, K.M.³

21
- 0036909567
- J. R. Peterson, T. J. Mitchison, Chem. Biol. 2002, 9, 1275-1285
- (2002) Chem. Biol. , vol.9 , pp. 1275-1285
- Peterson, J.R.¹ Mitchison, T.J.²

22
- 0038400185
- T. U. Mayer, Trends Cell Biol. 2003, 13, 270-277
- (2003) Trends Cell Biol. , vol.13 , pp. 270-277
- Mayer, T.U.¹

23
- 0038010068
- J.-R. J. Yeh, C. M. Crews, Dev. Cell, 2003, 5, 11-19
- (2003) Dev. Cell , vol.5 , pp. 11-19
- Yeh, J.-R.J.¹ Crews, C.M.²

24
- 0037079065
- B. R. Stockwell, Neuron, 2002, 36, 559-562
- (2002) Neuron , vol.36 , pp. 559-562
- Stockwell, B.R.¹

25
- 0034699382
- A. C. Bishop, J. A. Ubersax, D. T. Petsch, D. P. Matheos, N. S. Gray, J. Blethrow, E. Shimizu, J. Z. Tsien, P. G. Schultz, M. D. Rose, J. L. Wood, D. O. Morgan, K. M. Shokat, Nature, 2000, 407, 395-401
- (2000) Nature , vol.407 , pp. 395-401
- Bishop, A.C.¹ Ubersax, J.A.² Petsch, D.T.³ Matheos, D.P.⁴ Gray, N.S.⁵ Blethrow, J.⁶ Shimizu, E.⁷ Tsien, J.Z.⁸ Schultz, P.G.⁹ Rose, M.D.¹⁰ Wood, J.L.¹¹ Morgan, D.O.¹² Shokat, K.M.¹³

26
- 0037436506
- A. F. Straight, A. Cheung, J. Limouze, I. Chen, N. J. Westwood, J. R. Sellers, T. J. Mitchison, Science, 2003, 299, 1743-1747
- (2003) Science , vol.299 , pp. 1743-1747
- Straight, A.F.¹ Cheung, A.² Limouze, J.³ Chen, I.⁴ Westwood, N.J.⁵ Sellers, J.R.⁶ Mitchison, T.J.⁷

27
- 0142167588
- C. A. MacRae, R. T. Peterson, Chem. Biol. 2003, 10, 901-908
- (2003) Chem. Biol. , vol.10 , pp. 901-908
- Macrae, C.A.¹ Peterson, R.T.²

28
- 0034700166
- R. T. Peterson, B. A. Link, J. E. Dowling, S. L. Schreiber, Proc. Natl. Acad. Sci. USA, 2000, 97, 12965-12969
- (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12965-12969
- Peterson, R.T.¹ Link, B.A.² Dowling, J.E.³ Schreiber, S.L.⁴

29
- 18644368453
- M. Frank-Kamenetsky, X. M. Zhang, S. Bottega, O. Guicherit, H. Wichterle, H. Dudek, D. Bumcrot, F. Y. Wang, S. Jones, J. Shulok, L. L. Rubin, J. A. Porter, J. Biol. 2002, 1, 10
- (2002) J. Biol. , vol.1 , pp. 10
- Frank-Kamenetsky, M.¹ Zhang, X.M.² Bottega, S.³ Guicherit, O.⁴ Wichterle, H.⁵ Dudek, H.⁶ Bumcrot, D.⁷ Wang, F.Y.⁸ Jones, S.⁹ Shulok, J.¹⁰ Rubin, L.L.¹¹ Porter, J.A.¹²

30
- 3042744026
- S. Deng, P. G. Schultz, Nat. Biotechnol. 2004, 22, 833-840
- (2004) Nat. Biotechnol. , vol.22 , pp. 833-840
- Deng, S.¹ Schultz, P.G.²

31
- 0347717672
- S. Chen, Q. Zhang, X. Wu, P. G. Schultz, S. Ding, J. Am. Chem. Soc. 2004, 126, 410-411
- (2004) J. Am. Chem. Soc. , vol.126 , pp. 410-411
- Chen, S.¹ Zhang, Q.² Wu, X.³ Schultz, P.G.⁴ Ding, S.⁵

32
- 0037860938
- T. Berg, Angew. Chem. Int. Ed. 2003, 42, 2462-2481
- (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 2462-2481
- Berg, T.¹

33
- 1642512639
- M. Lepourcelet, Y.-N. P. Chen, D. S. France, H. Wang, P. Crews, F. Petersen, C. Bruseo, A. W. Wood, R. A. Shivdasani, Cancer Cell, 2004, 5, 91-102
- (2004) Cancer Cell , vol.5 , pp. 91-102
- Lepourcelet, M.¹ Chen, Y.-N.P.² France, D.S.³ Wang, H.⁴ Crews, P.⁵ Petersen, F.⁶ Bruseo, C.⁷ Wood, A.W.⁸ Shivdasani, R.A.⁹

34
- 0035818921
- M. Winn, E. B. Reilly, G. Liu, J. R. Huth, H.-S. Jae, J. Freeman, Z. Pei, Z. Xin, J. Lynch, J. Kester, T. W. von Geldern, S. Leitza, P. DeVries, R. Dickinson, D. Mussatto, G. F. Okasinski, J. Med. Chem. 2001, 44, 4393-4403
- (2001) J. Med. Chem. , vol.44 , pp. 4393-4403
- Winn, M.¹ Reilly, E.B.² Liu, G.³ Huth, J.R.⁴ Jae, H.-S.⁵ Freeman, J.⁶ Pei, Z.⁷ Xin, Z.⁸ Lynch, J.⁹ Kester, J.¹⁰ Von Geldern, T.W.¹¹ Leitza, S.¹² Devries, P.¹³ Dickinson, R.¹⁴ Mussatto, D.¹⁵ Okasinski, G.F.¹⁶

35
- 18244370299
- T. R. Gadek, D. J. Burdick, R. S. McDowell, M. S. Stanley, J. C. Marsters, Jr. K. J. Paris, D. A. Oare, M. E. Reynolds, C. Ladner, K. A. Zioncheck, W. P. Lee, P. Gribling, M. S. Dennis, N. J. Skelton, D. B. Tumas, K. R. Clark, S. M. Keating, M. H. Beresini, J. W. Tilley, L. G. Presta, S. C. Bodary, Science, 2002, 295, 1086-1089
- (2002) Science , vol.295 , pp. 1086-1089
- Gadek, T.R.¹ Burdick, D.J.² Mc Dowell, R.S.³ Stanley, M.S.⁴ Marsters, J.C.⁵ Paris, K.J.⁶ Oare, D.A.⁷ Reynolds, M.E.⁸ Ladner, C.⁹ Zioncheck, K.A.¹⁰ Lee, W.P.¹¹ Gribling, P.¹² Dennis, M.S.¹³ Skelton, N.J.¹⁴ Tumas, D.B.¹⁵ Clark, K.R.¹⁶ Keating, S.M.¹⁷ Beresini, M.H.¹⁸ Tilley, J.W.¹⁹ Presta, L.G.²⁰ Bodary, S.C.²¹ more..

36
- 0036753365
- A. Nahvi, N. Sudarsan, M. S. Ebert, X. Zou, K. L. Brown, R. R. Breaker, Chem. Biol. 2002, 9, 1043-1049
- (2002) Chem. Biol. , vol.9 , pp. 1043-1049
- Nahvi, A.¹ Sudarsan, N.² Ebert, M.S.³ Zou, X.⁴ Brown, K.L.⁵ Breaker, R.R.⁶

37
- 4644231100
- R. Micura, Angew. Chem. Int. Ed. 2004, 43, 4692-4694
- (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 4692-4694
- Micura, R.¹

38
- 0030951207
- J. M. Gottesfeld, L. Neely, J. W. Trauger, E. E. Baird, P. B. Dervan, Nature, 1997, 387, 202-205
- (1997) Nature , vol.387 , pp. 202-205
- Gottesfeld, J.M.¹ Neely, L.² Trauger, J.W.³ Baird, E.E.⁴ Dervan, P.B.⁵

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