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Volumn 16, Issue 8, 2010, Pages 2605-2616

Sonic hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells

Author keywords

[No Author keywords available]

Indexed keywords

DEFECTS; POLYMERASE CHAIN REACTION; STEM CELLS; TISSUE ENGINEERING;

EID: 77956079673     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0048     Document Type: Article
Times cited : (135)

References (39)
  • 1
    • 23344450107 scopus 로고    scopus 로고
    • Adipose-derived mesenchymal cells as a potential cell source for skeletal regeneration
    • Xu, Y., Malladi, P., Wagner, D.R., and Longaker, M.T. Adipose-derived mesenchymal cells as a potential cell source for skeletal regeneration. Curr Opin Mol Ther 7, 300, 2005.
    • (2005) Curr Opin Mol Ther , vol.7 , pp. 300
    • Xu, Y.1    Malladi, P.2    Wagner, D.R.3    Longaker, M.T.4
  • 3
    • 2342613539 scopus 로고    scopus 로고
    • Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
    • Nuttall, M.E., and Gimble, J.M. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol 4, 290, 2004.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 290
    • Nuttall, M.E.1    Gimble, J.M.2
  • 4
    • 2142808834 scopus 로고    scopus 로고
    • Fat's loss is bone's gain
    • Pei, L., and Tontonoz, P. Fat's loss is bone's gain. J Clin Invest 113, 805, 2004.
    • (2004) J Clin Invest , vol.113 , pp. 805
    • Pei, L.1    Tontonoz, P.2
  • 5
    • 33747618270 scopus 로고    scopus 로고
    • Osteogenic differentiation of mouse adipose-derived adult stromal cells requires re-tinoic acid and bone morphogenetic protein receptor type IB signaling
    • Wan, D.C., Shi, Y.Y., Nacamuli, R.P., Quarto, N., Lyons, K.M., and Longaker, M.T. Osteogenic differentiation of mouse adipose-derived adult stromal cells requires re-tinoic acid and bone morphogenetic protein receptor type IB signaling. Proc Natl Acad Sci USA 103, 12335, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12335
    • Wan, D.C.1    Shi, Y.Y.2    Nacamuli, R.P.3    Quarto, N.4    Lyons, K.M.5    Longaker, M.T.6
  • 6
    • 0033754122 scopus 로고    scopus 로고
    • The sonic hedgehog-patched-gli pathway in human development and disease
    • Villavicencio, E.H., Walterhouse, D.O., and Iannaccone, P.M. The sonic hedgehog-patched-gli pathway in human development and disease. Am J Hum Genet 67, 1047, 2000.
    • (2000) Am J Hum Genet , vol.67 , pp. 1047
    • Villavicencio, E.H.1    Walterhouse, D.O.2    Iannaccone, P.M.3
  • 7
    • 0034124786 scopus 로고    scopus 로고
    • Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites
    • Borycki, A., Brown, A.M., and Emerson, C.P., Jr. Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. Development 127, 2075, 2000.
    • (2000) Development , vol.127 , pp. 2075
    • Borycki, A.1    Brown, A.M.2    Emerson Jr., C.P.3
  • 8
    • 25444502854 scopus 로고    scopus 로고
    • Hedgehogs as negative regulators of the cell cycle
    • Neumann, C.J. Hedgehogs as negative regulators of the cell cycle. Cell Cycle 4, 1139, 2005.
    • (2005) Cell Cycle , vol.4 , pp. 1139
    • Neumann, C.J.1
  • 10
    • 32444449871 scopus 로고    scopus 로고
    • GLI transcription factors: Mediators of oncogenic hedgehog signalling
    • Kasper, M., Regl, G., Frischauf, A.M., and Aberger, F. GLI transcription factors: mediators of oncogenic hedgehog signalling. Eur J Cancer 42, 437, 2006.
    • (2006) Eur J Cancer , vol.42 , pp. 437
    • Kasper, M.1    Regl, G.2    Frischauf, A.M.3    Aberger, F.4
  • 11
    • 0346996354 scopus 로고    scopus 로고
    • Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells
    • van der Horst, G., Farih-Sips, H., Lowik, C.W., and Karperien, M. Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells. Bone 33, 899, 2003.
    • (2003) Bone , vol.33 , pp. 899
    • Van Der Horst, G.1    Farih-Sips, H.2    Lowik, C.W.3    Karperien, M.4
  • 12
    • 0142124746 scopus 로고    scopus 로고
    • Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion
    • Jemtland, R., Divieti, P., Lee, K., and Segre, G.V. Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion. Bone 32, 611, 2003.
    • (2003) Bone , vol.32 , pp. 611
    • Jemtland, R.1    Divieti, P.2    Lee, K.3    Segre, G.V.4
  • 15
    • 49249114978 scopus 로고    scopus 로고
    • Hedgehog signaling alters adipocyte maturation of human mesenchymal stem cells
    • Fontaine, C., Cousin, W., Plaisant, M., Dani, C., and Peraldi, P. Hedgehog signaling alters adipocyte maturation of human mesenchymal stem cells. Stem Cells 26, 1037, 2008.
    • (2008) Stem Cells , vol.26 , pp. 1037
    • Fontaine, C.1    Cousin, W.2    Plaisant, M.3    Dani, C.4    Peraldi, P.5
  • 16
    • 33645046358 scopus 로고    scopus 로고
    • Hedgehog signaling plays a conserved role in inhibiting fat formation
    • Suh, J.M., Gao, X., McKay, J., McKay, R., Salo, Z., and Graff, J.M. Hedgehog signaling plays a conserved role in inhibiting fat formation. Cell Metab 3, 25, 2006.
    • (2006) Cell Metab , vol.3 , pp. 25
    • Suh, J.M.1    Gao, X.2    McKay, J.3    McKay, R.4    Salo, Z.5    Graff, J.M.6
  • 17
    • 33746667771 scopus 로고    scopus 로고
    • Functions of vitamin D, retinoic acid, and dexamethasone on mouse adipose-derived mesenchymal cells (AMCs)
    • Malladi, P., Xu, Y., Yang, G.P., and Longaker, M.T. Functions of vitamin D, retinoic acid, and dexamethasone on mouse adipose-derived mesenchymal cells (AMCs). Tissue Eng 12, 2031, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 2031
    • Malladi, P.1    Xu, Y.2    Yang, G.P.3    Longaker, M.T.4
  • 18
    • 48049102795 scopus 로고    scopus 로고
    • Proliferation, osteogenic differentiation, and fgf-2 modulation of posterofrontal=sagittal suture-derived mesenchymal cells in vitro
    • James, A.W., Xu, Y., Wang, R., and Longaker, M.T. Proliferation, osteogenic differentiation, and fgf-2 modulation of posterofrontal=sagittal suture-derived mesenchymal cells in vitro. Plast Reconstr Surg 122, 53, 2008.
    • (2008) Plast Reconstr Surg , vol.122 , pp. 53
    • James, A.W.1    Xu, Y.2    Wang, R.3    Longaker, M.T.4
  • 19
    • 53349096948 scopus 로고    scopus 로고
    • Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration
    • Leucht, P., Kim, J.B., Amasha, R., James, A.W., Girod, S., and Helms, J.A. Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration. Development 135, 2845, 2008.
    • (2008) Development , vol.135 , pp. 2845
    • Leucht, P.1    Kim, J.B.2    Amasha, R.3    James, A.W.4    Girod, S.5    Helms, J.A.6
  • 22
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • Uccelli, A., Moretta, L., and Pistoia, V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 8, 726, 2008.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 23
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: Nature, biology, and potential applications
    • Bianco, P., Riminucci, M., Gronthos, S., and Robey, P.G. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19, 180, 2001.
    • (2001) Stem Cells , vol.19 , pp. 180
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 25
    • 13844257282 scopus 로고    scopus 로고
    • Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma=stem cells: The role of PPAR-gamma2 transcription factor and TGF-beta=BMP signaling pathways
    • Moerman, E.J., Teng, K., Lipschitz, D.A., and Lecka-Czernik, B. Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma=stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta=BMP signaling pathways. Aging Cell 3, 379, 2004.
    • (2004) Aging Cell , vol.3 , pp. 379
    • Moerman, E.J.1    Teng, K.2    Lipschitz, D.A.3    Lecka-Czernik, B.4
  • 27
    • 34548523808 scopus 로고    scopus 로고
    • PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats
    • Lin, T.H., Yang, R.S., Tang, C.H., Lin, C.P., and Fu, W.M. PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. Bone 41, 562, 2007.
    • (2007) Bone , vol.41 , pp. 562
    • Lin, T.H.1    Yang, R.S.2    Tang, C.H.3    Lin, C.P.4    Fu, W.M.5
  • 28
    • 33746846927 scopus 로고    scopus 로고
    • FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state
    • Quarto, N., and Longaker, M.T. FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state. Tissue Eng 12, 1405, 2006.
    • (2006) Tissue Eng , vol.12 , pp. 1405
    • Quarto, N.1    Longaker, M.T.2
  • 29
    • 73649114552 scopus 로고    scopus 로고
    • Human adipose-derived stem cells isolated from young and elderly women: Their differentiation potential and scaffold interaction during in vitro osteoblastic differentiation
    • De Girolamo, L., Lopa, S., Arrigoni, E., Sartori, M.F., Bar-uffaldi Preis, F.W., and Brini, A.T. Human adipose-derived stem cells isolated from young and elderly women: their differentiation potential and scaffold interaction during in vitro osteoblastic differentiation. Cytotherapy 11, 793, 2009.
    • (2009) Cytotherapy , vol.11 , pp. 793
    • De Girolamo, L.1    Lopa, S.2    Arrigoni, E.3    Sartori, M.F.4    Baruffaldi Preis, F.W.5    Brini, A.T.6
  • 30
    • 67349107689 scopus 로고    scopus 로고
    • The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells
    • Zhu, M., Kohan, E., Bradley, J., Hedrick, M., Benhaim, P., and Zuk, P. The effect of age on osteogenic, adipogenic and proliferative potential of female adipose-derived stem cells. J Tissue Eng Regen Med 3, 290, 2009.
    • (2009) J Tissue Eng Regen Med , vol.3 , pp. 290
    • Zhu, M.1    Kohan, E.2    Bradley, J.3    Hedrick, M.4    Benhaim, P.5    Zuk, P.6
  • 31
    • 23344443288 scopus 로고    scopus 로고
    • The osteogenic potential of adipose-derived mesenchymal cells is maintained with aging
    • Shi, Y.Y., Nacamuli, R.P., Salim, A., and Longaker, M.T. The osteogenic potential of adipose-derived mesenchymal cells is maintained with aging. Plast Reconstr Surg 116, 1686, 2005.
    • (2005) Plast Reconstr Surg , vol.116 , pp. 1686
    • Shi, Y.Y.1    Nacamuli, R.P.2    Salim, A.3    Longaker, M.T.4
  • 33
    • 33748531312 scopus 로고    scopus 로고
    • Inhibition of the anti-adipogenic Hedgehog signaling pathway by cyclopamine does not trigger adipocyte differentiation
    • Cousin, W., Dani, C., and Peraldi, P. Inhibition of the anti-adipogenic Hedgehog signaling pathway by cyclopamine does not trigger adipocyte differentiation. Biochem Biophys Res Commun 349, 799, 2006.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 799
    • Cousin, W.1    Dani, C.2    Peraldi, P.3
  • 34
    • 34447343823 scopus 로고    scopus 로고
    • Bone morpho-genetic proteins in clinical applications
    • Gautschi, O.P., Frey, S.P., and Zellweger, R. Bone morpho-genetic proteins in clinical applications. ANZ J Surg 77, 626, 2007.
    • (2007) ANZ J Surg , vol.77 , pp. 626
    • Gautschi, O.P.1    Frey, S.P.2    Zellweger, R.3
  • 37
    • 43449083485 scopus 로고    scopus 로고
    • Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs)
    • Quarto, N., Wan, D.C., and Longaker, M.T. Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs). Bone 42, 1040, 2008.
    • (2008) Bone , vol.42 , pp. 1040
    • Quarto, N.1    Wan, D.C.2    Longaker, M.T.3
  • 38
    • 77955373350 scopus 로고    scopus 로고
    • Divergent modulation of adipose-derived stromal cell differentiation by TGF-beta1 based on species of derivation
    • (In press)
    • Levi, B., James, A.W., Xu, Y., Commons, G.W., and Long-aker, M.T. Divergent modulation of adipose-derived stromal cell differentiation by TGF-beta1 based on species of derivation. Plast Reconstr Surg, 2010 (In press).
    • (2010) Plast Reconstr Surg
    • Levi, B.1    James, A.W.2    Xu, Y.3    Commons, G.W.4    Longaker, M.T.5
  • 39
    • 65249135916 scopus 로고    scopus 로고
    • Activation of hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells
    • Plaisant, M., Fontaine, C., Cousin, W., Rochet, N., Dani, C., and Peraldi, P. Activation of hedgehog signaling inhibits osteoblast differentiation of human mesenchymal stem cells. Stem Cells 27, 703, 2009.
    • (2009) Stem Cells , vol.27 , pp. 703
    • Plaisant, M.1    Fontaine, C.2    Cousin, W.3    Rochet, N.4    Dani, C.5    Peraldi, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.