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Volumn 8, Issue 1, 2013, Pages

Reduced Interleukin-4 Receptor α Expression on CD8+ T Cells Correlates with Higher Quality Anti-Viral Immunity

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84873169552     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055788     Document Type: Article
Times cited : (23)

References (36)
  • 1
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, et al. (2002) Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298: 850-854.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1    Wunderlich, J.R.2    Robbins, P.F.3    Yang, J.C.4    Hwu, P.5
  • 2
    • 0034097041 scopus 로고    scopus 로고
    • CD8+ T cell effector mechanisms in resistance to infection
    • Harty JT, Tvinnereim AR, White DW, (2000) CD8+ T cell effector mechanisms in resistance to infection. Annu Rev Immunol 18: 275-308.
    • (2000) Annu Rev Immunol , vol.18 , pp. 275-308
    • Harty, J.T.1    Tvinnereim, A.R.2    White, D.W.3
  • 3
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel RM, Doherty PC, (1974) Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 248: 701-702.
    • (1974) Nature , vol.248 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 4
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: implications for vaccine design
    • Seder RA, Darrah PA, Roederer M, (2008) T-cell quality in memory and protection: implications for vaccine design. Nat Rev Immunol 8: 247-258.
    • (2008) Nat Rev Immunol , vol.8 , pp. 247-258
    • Seder, R.A.1    Darrah, P.A.2    Roederer, M.3
  • 5
    • 0035253434 scopus 로고    scopus 로고
    • High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL
    • Derby M, Alexander-Miller M, Tse R, Berzofsky J, (2001) High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL. J Immunol 166: 1690-1697.
    • (2001) J Immunol , vol.166 , pp. 1690-1697
    • Derby, M.1    Alexander-Miller, M.2    Tse, R.3    Berzofsky, J.4
  • 6
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
    • (2007) J Exp Med , vol.204 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5
  • 7
    • 69249155108 scopus 로고    scopus 로고
    • Immunisation route-dependent expression of IL-4/IL-13 can modulate HIV-specific CD8(+) CTL avidity
    • Ranasinghe C, Ramshaw IA, (2009) Immunisation route-dependent expression of IL-4/IL-13 can modulate HIV-specific CD8(+) CTL avidity. Eur J Immunol 39: 1819-1830.
    • (2009) Eur J Immunol , vol.39 , pp. 1819-1830
    • Ranasinghe, C.1    Ramshaw, I.A.2
  • 8
    • 33846924548 scopus 로고    scopus 로고
    • Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles
    • Ranasinghe C, Turner SJ, McArthur C, Sutherland DB, Kim JH, et al. (2007) Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles. J Immunol 178: 2370-2379.
    • (2007) J Immunol , vol.178 , pp. 2370-2379
    • Ranasinghe, C.1    Turner, S.J.2    McArthur, C.3    Sutherland, D.B.4    Kim, J.H.5
  • 9
    • 77955506879 scopus 로고    scopus 로고
    • IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response
    • Apte SH, Groves P, Olver S, Baz A, Doolan DL, et al. (2010) IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response. J Immunol 185: 998-1004.
    • (2010) J Immunol , vol.185 , pp. 998-1004
    • Apte, S.H.1    Groves, P.2    Olver, S.3    Baz, A.4    Doolan, D.L.5
  • 10
    • 0027164561 scopus 로고
    • Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells
    • Erard F, Wild MT, Garcia-Sanz JA, Le Gros G, (1993) Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells. Science 260: 1802-1805.
    • (1993) Science , vol.260 , pp. 1802-1805
    • Erard, F.1    Wild, M.T.2    Garcia-Sanz, J.A.3    Le Gros, G.4
  • 11
    • 13544266571 scopus 로고    scopus 로고
    • Progressive differentiation and commitment of CD8+ T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4
    • Kienzle N, Olver S, Buttigieg K, Groves P, Janas ML, et al. (2005) Progressive differentiation and commitment of CD8+ T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4. J Immunol 174: 2021-2029.
    • (2005) J Immunol , vol.174 , pp. 2021-2029
    • Kienzle, N.1    Olver, S.2    Buttigieg, K.3    Groves, P.4    Janas, M.L.5
  • 12
    • 58749091674 scopus 로고    scopus 로고
    • Untangling the complex web of IL-4- and IL-13-mediated signaling pathways
    • Wills-Karp M, Finkelman FD, (2008) Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Sci Signal 1: pe55.
    • (2008) Sci Signal , vol.1
    • Wills-Karp, M.1    Finkelman, F.D.2
  • 13
    • 34548514010 scopus 로고    scopus 로고
    • IL-13 receptor isoforms: breaking through the complexity
    • Tabata Y, Khurana Hershey GK, (2007) IL-13 receptor isoforms: breaking through the complexity. Curr Allergy Asthma Rep 7: 338-345.
    • (2007) Curr Allergy Asthma Rep , vol.7 , pp. 338-345
    • Tabata, Y.1    Khurana Hershey, G.K.2
  • 14
    • 0032554784 scopus 로고    scopus 로고
    • Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
    • Barner M, Mohrs M, Brombacher F, Kopf M, (1998) Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr Biol 8: 669-672.
    • (1998) Curr Biol , vol.8 , pp. 669-672
    • Barner, M.1    Mohrs, M.2    Brombacher, F.3    Kopf, M.4
  • 15
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling
    • Mohrs M, Ledermann B, Kohler G, Dorfmuller A, Gessner A, et al. (1999) Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol 162: 7302-7308.
    • (1999) J Immunol , vol.162 , pp. 7302-7308
    • Mohrs, M.1    Ledermann, B.2    Kohler, G.3    Dorfmuller, A.4    Gessner, A.5
  • 16
    • 0035353154 scopus 로고    scopus 로고
    • The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway
    • Kawakami K, Taguchi J, Murata T, Puri RK, (2001) The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway. Blood 97: 2673-2679.
    • (2001) Blood , vol.97 , pp. 2673-2679
    • Kawakami, K.1    Taguchi, J.2    Murata, T.3    Puri, R.K.4
  • 17
    • 78650672614 scopus 로고    scopus 로고
    • IL-13Ralpha2 has a protective role in a mouse model of cutaneous inflammation
    • Sivaprasad U, Warrier MR, Gibson AM, Chen W, Tabata Y, et al. (2010) IL-13Ralpha2 has a protective role in a mouse model of cutaneous inflammation. J Immunol 185: 6802-6808.
    • (2010) J Immunol , vol.185 , pp. 6802-6808
    • Sivaprasad, U.1    Warrier, M.R.2    Gibson, A.M.3    Chen, W.4    Tabata, Y.5
  • 18
    • 0027972046 scopus 로고
    • An interleukin-4-induced transcription factor: IL-4 Stat
    • Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, et al. (1994) An interleukin-4-induced transcription factor: IL-4 Stat. Science 265: 1701-1706.
    • (1994) Science , vol.265 , pp. 1701-1706
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3    Ho, T.C.4    Brasseur, M.5
  • 20
    • 58149143039 scopus 로고    scopus 로고
    • Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity
    • Junttila IS, Mizukami K, Dickensheets H, Meier-Schellersheim M, Yamane H, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med 205: 2595-2608.
    • (2008) J Exp Med , vol.205 , pp. 2595-2608
    • Junttila, I.S.1    Mizukami, K.2    Dickensheets, H.3    Meier-Schellersheim, M.4    Yamane, H.5
  • 21
    • 34548792917 scopus 로고    scopus 로고
    • T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2
    • Tanaka Y, Hamano S, Gotoh K, Murata Y, Kunisaki Y, et al. (2007) T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2. Nat Immunol 8: 1067-1075.
    • (2007) Nat Immunol , vol.8 , pp. 1067-1075
    • Tanaka, Y.1    Hamano, S.2    Gotoh, K.3    Murata, Y.4    Kunisaki, Y.5
  • 22
    • 76249111890 scopus 로고    scopus 로고
    • Differential regulation of IL-4Ralpha expression by antigen versus cytokine stimulation characterizes Th2 progression in vivo
    • Perona-Wright G, Mohrs K, Mayer KD, Mohrs M, (2010) Differential regulation of IL-4Ralpha expression by antigen versus cytokine stimulation characterizes Th2 progression in vivo. J Immunol 184: 615-623.
    • (2010) J Immunol , vol.184 , pp. 615-623
    • Perona-Wright, G.1    Mohrs, K.2    Mayer, K.D.3    Mohrs, M.4
  • 23
    • 77956806285 scopus 로고    scopus 로고
    • Analysis of A47, an immunoprevalent protein of vaccinia virus, leads to a reevaluation of the total antiviral CD8+ T cell response
    • Yuen TJ, Flesch IE, Hollett NA, Dobson BM, Russell TA, et al. (2010) Analysis of A47, an immunoprevalent protein of vaccinia virus, leads to a reevaluation of the total antiviral CD8+ T cell response. J Virol 84: 10220-10229.
    • (2010) J Virol , vol.84 , pp. 10220-10229
    • Yuen, T.J.1    Flesch, I.E.2    Hollett, N.A.3    Dobson, B.M.4    Russell, T.A.5
  • 24
    • 0030839303 scopus 로고    scopus 로고
    • Antagonistic effects of interferon-gamma and interleukin-4 on fibroblast cultures
    • Serpier H, Gillery P, Salmon-Ehr V, Garnotel R, Georges N, et al. (1997) Antagonistic effects of interferon-gamma and interleukin-4 on fibroblast cultures. J Invest Dermatol 109: 158-162.
    • (1997) J Invest Dermatol , vol.109 , pp. 158-162
    • Serpier, H.1    Gillery, P.2    Salmon-Ehr, V.3    Garnotel, R.4    Georges, N.5
  • 25
    • 0029819130 scopus 로고    scopus 로고
    • Interleukin-4 mediates down regulation of antiviral cytokine expression and cytotoxic T-lymphocyte responses and exacerbates vaccinia virus infection in vivo
    • Sharma DP, Ramsay AJ, Maguire DJ, Rolph MS, Ramshaw IA, (1996) Interleukin-4 mediates down regulation of antiviral cytokine expression and cytotoxic T-lymphocyte responses and exacerbates vaccinia virus infection in vivo. J Virol 70: 7103-7107.
    • (1996) J Virol , vol.70 , pp. 7103-7107
    • Sharma, D.P.1    Ramsay, A.J.2    Maguire, D.J.3    Rolph, M.S.4    Ramshaw, I.A.5
  • 26
    • 33751224154 scopus 로고    scopus 로고
    • A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses
    • La Gruta NL, Doherty PC, Turner SJ, (2006) A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses. Eur J Immunol 36: 2951-2959.
    • (2006) Eur J Immunol , vol.36 , pp. 2951-2959
    • La Gruta, N.L.1    Doherty, P.C.2    Turner, S.J.3
  • 27
    • 44449161520 scopus 로고    scopus 로고
    • Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen
    • Kroger CJ, Amoah S, Alexander-Miller MA, (2008) Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen. J Immunol 180: 5784-5788.
    • (2008) J Immunol , vol.180 , pp. 5784-5788
    • Kroger, C.J.1    Amoah, S.2    Alexander-Miller, M.A.3
  • 28
    • 35349014587 scopus 로고    scopus 로고
    • Molecular signature of CD8+ T cell exhaustion during chronic viral infection
    • Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, et al. (2007) Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27: 670-684.
    • (2007) Immunity , vol.27 , pp. 670-684
    • Wherry, E.J.1    Ha, S.J.2    Kaech, S.M.3    Haining, W.N.4    Sarkar, S.5
  • 30
    • 0035154360 scopus 로고    scopus 로고
    • Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox
    • Jackson RJ, Ramsay AJ, Christensen CD, Beaton S, Hall DF, et al. (2001) Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox. J Virol 75: 1205-1210.
    • (2001) J Virol , vol.75 , pp. 1205-1210
    • Jackson, R.J.1    Ramsay, A.J.2    Christensen, C.D.3    Beaton, S.4    Hall, D.F.5
  • 31
    • 0028275905 scopus 로고
    • Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection
    • Maggi E, Giudizi MG, Biagiotti R, Annunziato F, Manetti R, et al. (1994) Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection. J Exp Med 180: 489-495.
    • (1994) J Exp Med , vol.180 , pp. 489-495
    • Maggi, E.1    Giudizi, M.G.2    Biagiotti, R.3    Annunziato, F.4    Manetti, R.5
  • 32
    • 18844399327 scopus 로고    scopus 로고
    • IL-4Ralpha signaling is important for CD8+ T cell cytotoxicity in the absence of CD4+ T cell help
    • Marsland BJ, Schmitz N, Kopf M, (2005) IL-4Ralpha signaling is important for CD8+ T cell cytotoxicity in the absence of CD4+ T cell help. Eur J Immunol 35: 1391-1398.
    • (2005) Eur J Immunol , vol.35 , pp. 1391-1398
    • Marsland, B.J.1    Schmitz, N.2    Kopf, M.3
  • 33
    • 23944434020 scopus 로고    scopus 로고
    • IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites
    • Morrot A, Hafalla JC, Cockburn IA, Carvalho LH, Zavala F, (2005) IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites. J Exp Med 202: 551-560.
    • (2005) J Exp Med , vol.202 , pp. 551-560
    • Morrot, A.1    Hafalla, J.C.2    Cockburn, I.A.3    Carvalho, L.H.4    Zavala, F.5
  • 34
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling
    • Mohrs M, Ledermann B, Kohler G, Dorfmuller A, Gessner A, et al. (1999) Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol 162: 7302-7308.
    • (1999) J Immunol , vol.162 , pp. 7302-7308
    • Mohrs, M.1    Ledermann, B.2    Kohler, G.3    Dorfmuller, A.4    Gessner, A.5
  • 35
    • 34548721076 scopus 로고    scopus 로고
    • IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3
    • Albanesi C, Fairchild HR, Madonna S, Scarponi C, De Pita O, et al. (2007) IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3. J Immunol 179: 984-992.
    • (2007) J Immunol , vol.179 , pp. 984-992
    • Albanesi, C.1    Fairchild, H.R.2    Madonna, S.3    Scarponi, C.4    De Pita, O.5
  • 36
    • 33746829947 scopus 로고    scopus 로고
    • Evaluation of fowlpox-vaccinia virus prime-boost vaccine strategies for high-level mucosal and systemic immunity against HIV-1
    • Ranasinghe C, Medveczky JC, Woltring D, Gao K, Thomson S, et al. (2006) Evaluation of fowlpox-vaccinia virus prime-boost vaccine strategies for high-level mucosal and systemic immunity against HIV-1. Vaccine 24: 5881-5895.
    • (2006) Vaccine , vol.24 , pp. 5881-5895
    • Ranasinghe, C.1    Medveczky, J.C.2    Woltring, D.3    Gao, K.4    Thomson, S.5


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