-
1
-
-
41849114954
-
Helminth infections: The great neglected tropical diseases
-
Hotez, P. J., P. J. Brindley, J.M. Bethony, C. H. King, E. J. Pearce, and J. Jacobson. 2008. Helminth infections: the great neglected tropical diseases. J. Clin. Invest. 118: 1311-1321.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1311-1321
-
-
Hotez, P.J.1
Brindley, P.J.2
Bethony, J.M.3
King, C.H.4
Pearce, E.J.5
Jacobson, J.6
-
2
-
-
0030935344
-
Cytokine regulation of host defense against parasitic gastrointestinal nematodes: Lessons from studies with rodent models
-
Finkelman, F. D., T. Shea-Donohue, J. Goldhill, C. A. Sullivan, S. C. Morris, K. B. Madden, W. C. Gause, and J. F. Urban, Jr. 1997. Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models. Annu. Rev. Immunol. 15: 505-533.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 505-533
-
-
Finkelman, F.D.1
Shea-Donohue, T.2
Goldhill, J.3
Sullivan, C.A.4
Morris, S.C.5
Madden, K.B.6
Gause, W.C.7
Urban Jr., J.F.8
-
3
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136: 2348-2357.
-
(1986)
J. Immunol.
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
4
-
-
0025082313
-
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
-
Le Gros, G., S. Z. Ben-Sasson, R. Seder, F. D. Finkelman, and W. E. Paul. 1990. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172: 921-929.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 921-929
-
-
Le Gros, G.1
Ben-Sasson, S.Z.2
Seder, R.3
Finkelman, F.D.4
Paul, W.E.5
-
5
-
-
0025222698
-
IL-4 directs the development of Th2-like helper effectors
-
Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145: 3796-3806.
-
(1990)
J. Immunol.
, vol.145
, pp. 3796-3806
-
-
Swain, S.L.1
Weinberg, A.D.2
English, M.3
Huston, G.4
-
6
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf, M., G. Le Gros, M. Bachmann, M. C. Lamers, H. Bluethmann, and G. Köhler. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362: 245-248.
-
(1993)
Nature
, vol.362
, pp. 245-248
-
-
Kopf, M.1
Le Gros, G.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, H.5
Köhler, G.6
-
7
-
-
0023818704
-
Regulation of IgG1 and IgE production by interleukin 4
-
Snapper, C. M., F. D. Finkelman, and W. E. Paul. 1988. Regulation of IgG1 and IgE production by interleukin 4. Immunol. Rev. 102: 51-75.
-
(1988)
Immunol. Rev.
, vol.102
, pp. 51-75
-
-
Snapper, C.M.1
Finkelman, F.D.2
Paul, W.E.3
-
8
-
-
0026328818
-
Generation and analysis of interleukin-4 deficient mice
-
Kühn, R., K. Rajewsky, and W. Müller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254: 707-710. (Pubitemid 21917392)
-
(1991)
Science
, vol.254
, Issue.5032
, pp. 707-710
-
-
Kuhn, R.1
Rajewsky, K.2
Muller, W.3
-
9
-
-
0031570939
-
IL-4 protects against TNF-a-mediated cachexia and death during acute schistosomiasis
-
Brunet, L. R., F. D. Finkelman, A. W. Cheever, M. A. Kopf, and E. J. Pearce. 1997. IL-4 protects against TNF-a-mediated cachexia and death during acute schistosomiasis. J. Immunol. 159: 777-785.
-
(1997)
J. Immunol.
, vol.159
, pp. 777-785
-
-
Brunet, L.R.1
Finkelman, F.D.2
Cheever, A.W.3
Kopf, M.A.4
Pearce, E.J.5
-
10
-
-
0026043865
-
Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice
-
Urban, J. F., Jr., I. M. Katona, W. E. Paul, and F. D. Finkelman. 1991. Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. Proc. Natl. Acad. Sci. USA 88: 5513-5517.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5513-5517
-
-
Urban Jr., J.F.1
Katona, I.M.2
Paul, W.E.3
Finkelman, F.D.4
-
11
-
-
5644221318
-
Insights into the pathogenesis of asthma utilizing murine models
-
Taube, C., A. Dakhama, and E. W. Gelfand. 2004. Insights into the pathogenesis of asthma utilizing murine models. Int. Arch. Allergy Immunol. 135: 173-186.
-
(2004)
Int. Arch. Allergy Immunol.
, vol.135
, pp. 173-186
-
-
Taube, C.1
Dakhama, A.2
Gelfand, E.W.3
-
12
-
-
0033010373
-
The IL- 4 receptor: Signaling mechanisms and biologic functions
-
Nelms, K., A. D. Keegan, J. Zamorano, J. J. Ryan, and W. E. Paul. 1999. The IL- 4 receptor: signaling mechanisms and biologic functions. Annu. Rev. Immunol. 17: 701-738.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
13
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda, K., J. van Deursen, M. Y. Sangster, S. R. Sarawar, R. T. Carson, R. A. Tripp, C. Chu, F. W. Quelle, T. Nosaka, D. A. Vignali, et al. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380: 630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.10
-
14
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
15
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda, K., T. Tanaka, W. Shi, M. Matsumoto, M. Minami, S. Kashiwamura, K. Nakanishi, N. Yoshida, T. Kishimoto, and S. Akira. 1996. Essential role of Stat6 in IL-4 signalling. Nature 380: 627-630.
-
(1996)
Nature
, vol.380
, pp. 627-630
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
Matsumoto, M.4
Minami, M.5
Kashiwamura, S.6
Nakanishi, K.7
Yoshida, N.8
Kishimoto, T.9
Akira, S.10
-
16
-
-
58149143039
-
Tuning sensitivity to IL-4 and IL-13: Differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity
-
Junttila, I. S., K. Mizukami, H. Dickensheets, M. Meier-Schellersheim, H. Yamane, R. P. Donnelly, and W. E. Paul. 2008. Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity. J. Exp. Med. 205: 2595-2608.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2595-2608
-
-
Junttila, I.S.1
Mizukami, K.2
Dickensheets, H.3
Meier-Schellersheim, M.4
Yamane, H.5
Donnelly, R.P.6
Paul, W.E.7
-
17
-
-
0011124007
-
Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression
-
Ohara, J., and W. E. Paul. 1988. Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression. Proc. Natl. Acad. Sci. USA 85: 8221-8225.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8221-8225
-
-
Ohara, J.1
Paul, W.E.2
-
18
-
-
0026491008
-
Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level
-
Dokter, W. H., P. Borger, D. Hendriks, I. van der Horst, M. R. Halie, and E. Vellenga. 1992. Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level. Blood 80: 2721-2728.
-
(1992)
Blood
, vol.80
, pp. 2721-2728
-
-
Dokter, W.H.1
Borger, P.2
Hendriks, D.3
Van Der Horst, I.4
Halie, M.R.5
Vellenga, E.6
-
19
-
-
0025822170
-
IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells
-
Renz, H., J. Domenico, and E.W. Gelfand. 1991. IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells. J. Immunol. 146: 3049-3055.
-
(1991)
J. Immunol.
, vol.146
, pp. 3049-3055
-
-
Renz, H.1
Domenico, J.2
Gelfand, E.W.3
-
20
-
-
54549103162
-
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor a-chain expression
-
Liao, W., D. E. Schones, J. Oh, Y. Cui, K. Cui, T. Y. Roh, K. Zhao, and W. J. Leonard. 2008. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor a-chain expression. Nat. Immunol. 9: 1288-1296.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1288-1296
-
-
Liao, W.1
Schones, D.E.2
Oh, J.3
Cui, Y.4
Cui, K.5
Roh, T.Y.6
Zhao, K.7
Leonard, W.J.8
-
21
-
-
0034877815
-
Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter
-
Mohrs, M., K. Shinkai, K. Mohrs, and R. M. Locksley. 2001. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity 15: 303-311.
-
(2001)
Immunity
, vol.15
, pp. 303-311
-
-
Mohrs, M.1
Shinkai, K.2
Mohrs, K.3
Locksley, R.M.4
-
22
-
-
26644448473
-
A two-step process for cytokine production revealed by IL-4 dual-reporter mice
-
Mohrs, K., A. E. Wakil, N. Killeen, R. M. Locksley, and M. Mohrs. 2005. A two-step process for cytokine production revealed by IL-4 dual-reporter mice. Immunity 23: 419-429.
-
(2005)
Immunity
, vol.23
, pp. 419-429
-
-
Mohrs, K.1
Wakil, A.E.2
Killeen, N.3
Locksley, R.M.4
Mohrs, M.5
-
23
-
-
0033564686
-
Differences between IL-4- And IL-4 receptor α-deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling
-
Mohrs, M., B. Ledermann, G. Köhler, A. Dorfmüller, A. Gessner, and F. Brombacher. 1999. Differences between IL-4- and IL-4 receptor α-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J. Immunol. 162: 7302-7308. (Pubitemid 29277704)
-
(1999)
Journal of Immunology
, vol.162
, Issue.12
, pp. 7302-7308
-
-
Mohrs, M.1
Ledermann, B.2
Kohler, G.3
Dorfmuller, A.4
Gessner, A.5
Brombacher, F.6
-
24
-
-
0032715407
-
Stat6-dependent and -independent pathways for IL-4 production
-
Kaplan, M. H., A. L. Wurster, S. T. Smiley, and M. J. Grusby. 1999. Stat6-dependent and -independent pathways for IL-4 production. J. Immunol. 163: 6536-6540.
-
(1999)
J. Immunol.
, vol.163
, pp. 6536-6540
-
-
Kaplan, M.H.1
Wurster, A.L.2
Smiley, S.T.3
Grusby, M.J.4
-
25
-
-
0026613009
-
Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells
-
Philpott, K. L., J. L. Viney, G. Kay, S. Rastan, E. M. Gardiner, S. Chae, A. C. Hayday, and M. J. Owen. 1992. Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells. Science 256: 1448-1452.
-
(1992)
Science
, vol.256
, pp. 1448-1452
-
-
Philpott, K.L.1
Viney, J.L.2
Kay, G.3
Rastan, S.4
Gardiner, E.M.5
Chae, S.6
Hayday, A.C.7
Owen, M.J.8
-
26
-
-
0141924778
-
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
-
Stetson, D. B., M. Mohrs, R. L. Reinhardt, J. L. Baron, Z. E. Wang, L. Gapin, M. Kronenberg, and R. M. Locksley. 2003. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J. Exp. Med. 198: 1069-1076.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1069-1076
-
-
Stetson, D.B.1
Mohrs, M.2
Reinhardt, R.L.3
Baron, J.L.4
Wang, Z.E.5
Gapin, L.6
Kronenberg, M.7
Locksley, R.M.8
-
27
-
-
0036196669
-
Tracking Salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection
-
McSorley, S. J., S. Asch, M. Costalonga, R. L. Reinhardt, and M. K. Jenkins. 2002. Tracking Salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity 16: 365-377.
-
(2002)
Immunity
, vol.16
, pp. 365-377
-
-
McSorley, S.J.1
Asch, S.2
Costalonga, M.3
Reinhardt, R.L.4
Jenkins, M.K.5
-
29
-
-
0028409436
-
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
-
Scott, B., R. Liblau, S. Degermann, L. A. Marconi, L. Ogata, A. J. Caton, H. O. McDevitt, and D. Lo. 1994. A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity 1: 73-83.
-
(1994)
Immunity
, vol.1
, pp. 73-83
-
-
Scott, B.1
Liblau, R.2
Degermann, S.3
Marconi, L.A.4
Ogata, L.5
Caton, A.J.6
McDevitt, H.O.7
Lo, D.8
-
30
-
-
0037451170
-
Fibrin-mediated protection against infection-stimulated immunopathology
-
Johnson, L. L., K. N. Berggren, F. M. Szaba, W. Chen, and S. T. Smiley. 2003. Fibrin-mediated protection against infection-stimulated immunopathology. J. Exp. Med. 197: 801-806.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 801-806
-
-
Johnson, L.L.1
Berggren, K.N.2
Szaba, F.M.3
Chen, W.4
Smiley, S.T.5
-
31
-
-
0030239647
-
Two Distinct Stimulus-Dependent Pathways Lead to Production of Soluble Murine Interleukin-4 Receptor
-
Blum, H., M. Wolf, K. Enssle, M. Röllinghoff, and A. Gessner. 1996. Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor. J. Immunol. 157: 1846-1853. (Pubitemid 126449655)
-
(1996)
Journal of Immunology
, vol.157
, Issue.5
, pp. 1846-1853
-
-
Blum, H.1
Wolf, M.2
Enssle, K.3
Rollinghoff, M.4
Gessner, A.5
-
32
-
-
0024317761
-
The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms
-
Mosley, B., M. P. Beckmann, C. J. March, R. L. Idzerda, S. D. Gimpel, T. VandenBos, D. Friend, A. Alpert, D. Anderson, J. Jackson, et al. 1989. The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms. Cell 59: 335-348.
-
(1989)
Cell
, vol.59
, pp. 335-348
-
-
Mosley, B.1
Beckmann, M.P.2
March, C.J.3
Idzerda, R.L.4
Gimpel, S.D.5
Vandenbos, T.6
Friend, D.7
Alpert, A.8
Anderson, D.9
Jackson, J.10
-
33
-
-
26844547910
-
Systemic dissemination and persistence of Th2 and type 2 cells in response to infection with a strictly enteric nematode parasite
-
Mohrs, K., D. P. Harris, F. E. Lund, and M. Mohrs. 2005. Systemic dissemination and persistence of Th2 and type 2 cells in response to infection with a strictly enteric nematode parasite. J. Immunol. 175: 5306-5313. (Pubitemid 41456416)
-
(2005)
Journal of Immunology
, vol.175
, Issue.8
, pp. 5306-5313
-
-
Mohrs, K.1
Harris, D.P.2
Lund, F.E.3
Mohrs, M.4
-
34
-
-
0037220059
-
The role of OX40 ligand interactions in the development of the Th2 response to the gastrointestinal nematode parasite Heligmosomoides polygyrus
-
Ekkens, M. J., Z. Liu, Q. Liu, J. Whitmire, S. Xiao, A. Foster, J. Pesce, J. VanNov, A. H. Sharpe, J. F. Urban, and W. C. Gause. 2003. The role of OX40 ligand interactions in the development of the Th2 response to the gastrointestinal nematode parasite Heligmosomoides polygyrus. J. Immunol. 170: 384-393.
-
(2003)
J. Immunol.
, vol.170
, pp. 384-393
-
-
Ekkens, M.J.1
Liu, Z.2
Liu, Q.3
Whitmire, J.4
Xiao, S.5
Foster, A.6
Pesce, J.7
Vannov, J.8
Sharpe, A.H.9
Urban, J.F.10
Gause, W.C.11
-
35
-
-
34447565046
-
Unexpected phenotype of STAT6 heterozygous mice implies distinct STAT6 dosage requirements for different IL-4 functions
-
Burgis, S., and A. Gessner. 2007. Unexpected phenotype of STAT6 heterozygous mice implies distinct STAT6 dosage requirements for different IL-4 functions. Int. Arch. Allergy Immunol. 143: 263-268.
-
(2007)
Int. Arch. Allergy Immunol.
, vol.143
, pp. 263-268
-
-
Burgis, S.1
Gessner, A.2
-
36
-
-
0036831673
-
The immunology of susceptibility and resistance to Leishmania major in mice
-
Sacks, D., and N. Noben-Trauth. 2002. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2: 845-858.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 845-858
-
-
Sacks, D.1
Noben-Trauth, N.2
-
38
-
-
4344647601
-
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
-
Min, B., M. Prout, J. Hu-Li, J. Zhu, D. Jankovic, E. S. Morgan, J. F. Urban, Jr., A. M. Dvorak, F. D. Finkelman, G. LeGros, et al. 2004. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J. Exp. Med. 200:507-517.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 507-517
-
-
Min, B.1
Prout, M.2
Hu-Li, J.3
Zhu, J.4
Jankovic, D.5
Morgan, E.S.6
Urban Jr., J.F.7
Dvorak, A.M.8
Finkelman, F.D.9
Legros, G.10
-
39
-
-
0034162535
-
Stat6 regulation of in vivo IL-4 responses
-
Finkelman, F. D., S. C. Morris, T. Orekhova, M. Mori, D. Donaldson, S. L. Reiner, N. L. Reilly, L. Schopf, and J. F. Urban, Jr. 2000. Stat6 regulation of in vivo IL-4 responses. J. Immunol. 164: 2303-2310.
-
(2000)
J. Immunol.
, vol.164
, pp. 2303-2310
-
-
Finkelman, F.D.1
Morris, S.C.2
Orekhova, T.3
Mori, M.4
Donaldson, D.5
Reiner, S.L.6
Reilly, N.L.7
Schopf, L.8
Urban Jr., J.F.9
-
40
-
-
0032738991
-
Development of an assay to measure in vivo cytokine production in the mouse
-
Finkelman, F. D., and S. C. Morris. 1999. Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunol. 11: 1811-1818.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1811-1818
-
-
Finkelman, F.D.1
Morris, S.C.2
-
41
-
-
34548792917
-
T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2
-
Tanaka, Y., S. Hamano, K. Gotoh, Y. Murata, Y. Kunisaki, A. Nishikimi, R. Takii, M. Kawaguchi, A. Inayoshi, S. Masuko, et al. 2007. T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2. Nat. Immunol. 8: 1067-1075.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1067-1075
-
-
Tanaka, Y.1
Hamano, S.2
Gotoh, K.3
Murata, Y.4
Kunisaki, Y.5
Nishikimi, A.6
Takii, R.7
Kawaguchi, M.8
Inayoshi, A.9
Masuko, S.10
-
42
-
-
65549138091
-
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse
-
Maldonado, R. A., M. A. Soriano, L. C. Perdomo, K. Sigrist, D. J. Irvine, T. Decker, and L. H. Glimcher. 2009. Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. J. Exp. Med. 206: 877-892.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 877-892
-
-
Maldonado, R.A.1
Soriano, M.A.2
Perdomo, L.C.3
Sigrist, K.4
Irvine, D.J.5
Decker, T.6
Glimcher, L.H.7
-
43
-
-
0347382593
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
-
Kaech, S. M., J. T. Tan, E. J. Wherry, B. T. Konieczny, C. D. Surh, and R. Ahmed. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4: 1191-1198.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1191-1198
-
-
Kaech, S.M.1
Tan, J.T.2
Wherry, E.J.3
Konieczny, B.T.4
Surh, C.D.5
Ahmed, R.6
-
44
-
-
0034332403
-
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
-
Schluns, K. S., W. C. Kieper, S. C. Jameson, and L. Lefrançois. 2000. Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat. Immunol. 1: 426-432.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 426-432
-
-
Schluns, K.S.1
Kieper, W.C.2
Jameson, S.C.3
Lefrançois, L.4
-
45
-
-
0035070303
-
Specificity in cytokine signal transduction: Lessons learned from the IL-3/IL-5/GM-CSF receptor family
-
Geijsen, N., L. Koenderman, and P. J. Coffer. 2001. Specificity in cytokine signal transduction: lessons learned from the IL-3/IL-5/GM-CSF receptor family. Cytokine Growth Factor Rev. 12: 19-25.
-
(2001)
Cytokine Growth Factor Rev.
, vol.12
, pp. 19-25
-
-
Geijsen, N.1
Koenderman, L.2
Coffer, P.J.3
-
47
-
-
56649089785
-
A gene-dosage effect for interleukin-4 receptor α-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis
-
Müller, U., W. Stenzel, G. Köhler, T. Polte, M. Blessing, A. Mann, D. Piehler, F. Brombacher, and G. Alber. 2008. A gene-dosage effect for interleukin-4 receptor α-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis. J. Infect. Dis. 198: 1714-1721.
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 1714-1721
-
-
Müller, U.1
Stenzel, W.2
Köhler, G.3
Polte, T.4
Blessing, M.5
Mann, A.6
Piehler, D.7
Brombacher, F.8
Alber, G.9
-
48
-
-
0033732322
-
A targeted mutation in the IL-4Rα gene protects mice against autoimmune diabetes
-
Radu, D. L., N. Noben-Trauth, J. Hu-Li, W. E. Paul, and C. A. Bona. 2000. A targeted mutation in the IL-4Rα gene protects mice against autoimmune diabetes. Proc. Natl. Acad. Sci. USA 97: 12700-12704.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12700-12704
-
-
Radu, D.L.1
Noben-Trauth, N.2
Hu-Li, J.3
Paul, W.E.4
Bona, C.A.5
-
49
-
-
0037442130
-
Stat signals release activated naive Th cells from an anergic checkpoint
-
Mohrs, M., D. A. Lacy, and R. M. Locksley. 2003. Stat signals release activated naive Th cells from an anergic checkpoint. J. Immunol. 170: 1870-1876. (Pubitemid 36197404)
-
(2003)
Journal of Immunology
, vol.170
, Issue.4
, pp. 1870-1876
-
-
Mohrs, M.1
Lacy, D.A.2
Locksley, R.M.3
-
50
-
-
0035070195
-
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
-
Grogan, J. L., M. Mohrs, B. Harmon, D. A. Lacy, J. W. Sedat, and R. M. Locksley. 2001. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 14: 205-215.
-
(2001)
Immunity
, vol.14
, pp. 205-215
-
-
Grogan, J.L.1
Mohrs, M.2
Harmon, B.3
Lacy, D.A.4
Sedat, J.W.5
Locksley, R.M.6
-
51
-
-
0344806280
-
Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression
-
Richter, A., M. Löhning, and A. Radbruch. 1999. Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression. J. Exp. Med. 190: 1439-1450.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1439-1450
-
-
Richter, A.1
Löhning, M.2
Radbruch, A.3
-
52
-
-
0038638583
-
An epigenetic view of helper T cell differentiation
-
Ansel, K. M., D. U. Lee, and A. Rao. 2003. An epigenetic view of helper T cell differentiation. Nat. Immunol. 4: 616-623.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 616-623
-
-
Ansel, K.M.1
Lee, D.U.2
Rao, A.3
-
53
-
-
13544265658
-
IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites
-
Liu, Z., Q. Liu, H. Hamed, R. M. Anthony, A. Foster, F. D. Finkelman, J. F. Urban, Jr., and W. C. Gause. 2005. IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites. J. Immunol. 174: 2242-2249.
-
(2005)
J. Immunol.
, vol.174
, pp. 2242-2249
-
-
Liu, Z.1
Liu, Q.2
Hamed, H.3
Anthony, R.M.4
Foster, A.5
Finkelman, F.D.6
Urban Jr., J.F.7
Gause, W.C.8
-
54
-
-
61949121872
-
Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus
-
Wojciechowski, W., D. P. Harris, F. Sprague, B. Mousseau, M. Makris, K. Kusser, T. Honjo, K. Mohrs, M. Mohrs, T. Randall, et al. 2009. Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus. Immunity 30: 421-433.
-
(2009)
Immunity
, vol.30
, pp. 421-433
-
-
Wojciechowski, W.1
Harris, D.P.2
Sprague, F.3
Mousseau, B.4
Makris, M.5
Kusser, K.6
Honjo, T.7
Mohrs, K.8
Mohrs, M.9
Randall, T.10
-
55
-
-
1642398043
-
Interleukin 2 plays a central role in Th2 differentiation
-
Cote-Sierra, J., G. Foucras, L. Guo, L. Chiodetti, H. A. Young, J. Hu-Li, J. Zhu, and W. E. Paul. 2004. Interleukin 2 plays a central role in Th2 differentiation. Proc. Natl. Acad. Sci. USA 101: 3880-3885.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3880-3885
-
-
Cote-Sierra, J.1
Foucras, G.2
Guo, L.3
Chiodetti, L.4
Young, H.A.5
Hu-Li, J.6
Zhu, J.7
Paul, W.E.8
-
56
-
-
1642306579
-
IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88
-
Eisenbarth, S. C., A. Zhadkevich, P. Ranney, C.A. Herrick, and K. Bottomly. 2004. IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88. J. Immunol. 172: 4527-4534.
-
(2004)
J. Immunol.
, vol.172
, pp. 4527-4534
-
-
Eisenbarth, S.C.1
Zhadkevich, A.2
Ranney, P.3
Herrick, C.A.4
Bottomly, K.5
-
57
-
-
58149184309
-
A new mechanism for inhalational priming: IL-4 bypasses innate immune signals
-
Dittrich, A. M., H. C. Chen, L. Xu, P. Ranney, S. Connolly, T. O. Yarovinsky, and H. K. Bottomly. 2008. A new mechanism for inhalational priming: IL-4 bypasses innate immune signals. J. Immunol. 181: 7307-7315.
-
(2008)
J. Immunol.
, vol.181
, pp. 7307-7315
-
-
Dittrich, A.M.1
Chen, H.C.2
Xu, L.3
Ranney, P.4
Connolly, S.5
Yarovinsky, T.O.6
Bottomly, H.K.7
-
58
-
-
0030903223
-
Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. VI. Specific immunotherapy prevents the onset of new sensitizations in children
-
Des Roches, A., L. Paradis, J. L. Menardo, S. Bouges, J. P. Daurés, and J. Bousquet. 1997. Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. VI. Specific immunotherapy prevents the onset of new sensitizations in children. J. Allergy Clin. Immunol. 99: 450-453.
-
(1997)
J. Allergy Clin. Immunol.
, vol.99
, pp. 450-453
-
-
Des Roches, A.1
Paradis, L.2
Menardo, J.L.3
Bouges, S.4
Daurés, J.P.5
Bousquet, J.6
-
59
-
-
0034847103
-
Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study
-
Pajno, G. B., G. Barberio, F. De Luca, L. Morabito, and S. Parmiani. 2001. Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study. Clin. Exp. Allergy 31: 1392-1397.
-
(2001)
Clin. Exp. Allergy
, vol.31
, pp. 1392-1397
-
-
Pajno, G.B.1
Barberio, G.2
De Luca, F.3
Morabito, L.4
Parmiani, S.5
-
60
-
-
0023750570
-
IL-4/Bcell stimulatory factor 1 stimulates T cell growth by an IL-2-independent mechanism
-
Brown, M., J. Hu-Li, and W. E. Paul. 1988. IL-4/Bcell stimulatory factor 1 stimulates T cell growth by an IL-2-independent mechanism. J. Immunol. 141: 504-511.
-
(1988)
J. Immunol.
, vol.141
, pp. 504-511
-
-
Brown, M.1
Hu-Li, J.2
Paul, W.E.3
-
61
-
-
0022872021
-
Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation
-
Fernandez-Botran, R., V. M. Sanders, K. G. Oliver, Y. W. Chen, P. H. Krammer, J.W. Uhr, and E. S.Vitetta. 1986. Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation. Proc. Natl. Acad. Sci. USA 83: 9689-9693.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 9689-9693
-
-
Fernandez-Botran, R.1
Sanders, V.M.2
Oliver, K.G.3
Chen, Y.W.4
Krammer, P.H.5
Uhr, J.W.6
Vitetta, E.S.7
-
62
-
-
0347594000
-
IL-7 promotes the transition of CD4 effectors to persistent memory cells
-
Li, J., G. Huston, and S. L. Swain. 2003. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J. Exp. Med. 198: 1807-1815.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1807-1815
-
-
Li, J.1
Huston, G.2
Swain, S.L.3
-
63
-
-
62849090439
-
Cytokine-secreting follicular T cells shape the antibody repertoire
-
Reinhardt, R. L., H. E. Liang, and R. M. Locksley. 2009. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat. Immunol. 10: 385-393.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 385-393
-
-
Reinhardt, R.L.1
Liang, H.E.2
Locksley, R.M.3
-
64
-
-
65549114338
-
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
-
King, I. L., and M. Mohrs. 2009. IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med. 206: 1001-1007.
-
(2009)
J Exp Med.
, vol.206
, pp. 1001-1007
-
-
King, I.L.1
Mohrs, M.2
-
65
-
-
65549134481
-
T follicular helper cells differentiate from Th2 cells in response to helminth antigens
-
Zaretsky, A. G., J. J. Taylor, I. L. King, F. A. Marshall, M. Mohrs, and E. J. Pearce. 2009. T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J Exp Med. 206: 991-999.
-
(2009)
J Exp Med.
, vol.206
, pp. 991-999
-
-
Zaretsky, A.G.1
Taylor, J.J.2
King, I.L.3
Marshall, F.A.4
Mohrs, M.5
Pearce, E.J.6
-
66
-
-
0036717296
-
The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: Reciprocal regulation by interleukin (IL)-4 and IL-12
-
Lee, B. O., L. Haynes, S. M. Eaton, S. L. Swain, and T. D. Randall. 2002. The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12. J. Exp. Med. 196: 693-704.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 693-704
-
-
Lee, B.O.1
Haynes, L.2
Eaton, S.M.3
Swain, S.L.4
Randall, T.D.5
-
67
-
-
33846632842
-
Interleukin-7 receptor expression: Intelligent design
-
Mazzucchelli, R., and S. K. Durum. 2007. Interleukin-7 receptor expression: intelligent design. Nat. Rev. Immunol. 7: 144-154.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 144-154
-
-
Mazzucchelli, R.1
Durum, S.K.2
|