MiR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cells

BMC Genomics

Volumn 14, Issue 1, 2013, Pages

  Barbagallo, Davide ^a   Piro, Salvatore ^a   Condorelli, Angelo G ^a   Mascali, Loriana G ^a   Urbano, Francesca ^a   Parrinello, Nunziatina ^a   Monello, Adelina ^a   Statello, Luisa ^a   Ragusa, Marco ^a   Rabuazzo, Agata M ^a   Di Pietro, Cinzia ^a   Purrello, Francesco ^a   Purrello, Michele ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Apoptosis; Cellular networks; Diabetes mellitus; Mammalian pancreatic and cells; microRNA transcriptome; Proinflammatory cytokines

Indexed keywords

CYTOKINE; INSULIN RECEPTOR SUBSTRATE 1; MICRORNA; MICRORNA 296 3P; MICRORNA 298 5P; MITOGEN ACTIVATED PROTEIN KINASE; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN C RECEPTOR BETA; TRANSCRIPTION FACTOR MAFB; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSFECTION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEADY STATE; TRANSCRIPTOMICS; UPREGULATION;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CYTOKINES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLUCAGON-SECRETING CELLS; HUMANS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-SECRETING CELLS; MICE; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTORS; TRANSCRIPTOME; TRANSFECTION;

MAMMALIA; MURINAE; RODENTIA;

EID: 84872910667     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-14-62     Document Type: Article

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