Specific alterations of the microRNA transcriptome and global network structure in colorectal cancer after treatment with MAPK/ERK inhibitors

Journal of Molecular Medicine

Volumn 90, Issue 12, 2012, Pages 1421-1438

  Ragusa, Marco ^a   Statello, Luisa ^a   Maugeri, Marco ^a   Majorana, Alessandra ^a   Barbagallo, Davide ^a   Salito, Loredana ^a   Sammito, Mariangela ^a   Santonocito, Manuela ^a   Angelica, Rosario ^a   Cavallaro, Andrea ^a   Scalia, Marina ^a   Caltabiano, Rosario ^a   Privitera, Giuseppe ^a   Biondi, Antonio ^a   Di Vita, Maria ^a   Cappellani, Alessandro ^a   Vasquez, Enrico ^a   Lanzafame, Salvatore ^a   Tendi, Elisabetta ^b   Celeste, Salvatore ^b   Di Pietro, Cinzia ^a   Basile, Francesco ^a   Purrello, Michele ^a   more..

^a UNIVERSITY OF CATANIA   (Italy)

^b European Drug Safety and Metabolism Research Center Myrmex   (Italy)

Author keywords

Cellular networks; Colorectal cancer; ERK MAPK pathway; miRNA profile; miRNA protein targets

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; FR 180204; K RAS PROTEIN; MICRORNA; MICRORNA 1226; MICRORNA 135B; MICRORNA 372; MICRORNA 663B; MICRORNA 720; MICRORNA 92A 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTOME; UNCLASSIFIED DRUG; WAY 265506;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL PRACTICE; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENETIC REGULATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE K RAS; RANK SUM TEST; SIGNAL TRANSDUCTION; TUMOR BIOPSY; WILD TYPE;

APOPTOSIS; BLOTTING, WESTERN; BUTADIENES; CACO-2 CELLS; CELL MOVEMENT; CELL SURVIVAL; COLORECTAL NEOPLASMS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HCT116 CELLS; HUMANS; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; PYRAZOLES; PYRIDAZINES; TRANSCRIPTOME;

EID: 84884211395     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-012-0918-8     Document Type: Article

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