Ombuin-3-O-β-d-glucopyranoside from Gynostemma pentaphyllum is a dual agonistic ligand of peroxisome proliferator-activated receptors α and δ/β

Biochemical and Biophysical Research Communications

Volumn 430, Issue 4, 2013, Pages 1322-1328

  Malek, Mastura Abd ^a   Hoang, Minh Hien ^a   Jia, Yaoyao ^a   Lee, Ji Hae ^a   Jun, Hee Jin ^a   Lee, Dong Ho ^a   Lee, Hak Ju ^b   Lee, Chul ^c   Lee, Myung Koo ^c   Hwang, Bang Yeon ^c   Lee, Sung Joon ^a  

^a Korea University   (South Korea)

^b Korea Food Research Institute   (South Korea)

^c Chungbuk National University   (South Korea)

Author keywords

Dual agonist; Lipid metabolism; Ombuin 3 O d glucopyranoside; PPARs

Indexed keywords

[4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; ABC TRANSPORTER A1; ABC TRANSPORTER G1; ACYL COENZYME A DESATURASE; CHOLESTEROL; FENOFIBRATE; FLAVONOID; GYNOSTEMMA PENTAPHYLLUM EXTRACT; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; OMBUINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CELL STRAIN HEPG2; CHOLESTEROL TRANSPORT; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOWN REGULATION; ENZYME ACTIVATION; EXTRACTION; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE RESONANCE ENERGY TRANSFER; GYNOSTEMMA PENTAPHYLLUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGAND BINDING; LIPID METABOLISM; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURFACE PLASMON RESONANCE; TRANSACTIVATION;

ANIMALS; CELL LINE; FATTY ACIDS; FLAVONES; FLAVONOIDS; GENE EXPRESSION; GLUCOSIDES; GYNOSTEMMA; HEP G2 CELLS; HUMANS; LIGANDS; LIPID METABOLISM; LIVER; PPAR ALPHA; PPAR DELTA; PPAR-BETA;

GYNOSTEMMA PENTAPHYLLUM;

EID: 84872839460     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.12.020     Document Type: Article

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