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Volumn 11, Issue 4, 2008, Pages 709-716

Potential hypoglycemic effect of an ethanol extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db mice

Author keywords

Blood glucose lowering; C57BL KsJ db db mice; Gypenosides; Type 2 diabetes

Indexed keywords

ALCOHOL; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GYNOSTEMMA PENTAPHYLLUM EXTRACT; GYPENOSIDE; INSULIN; ROSIGLITAZONE;

EID: 57349083738     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2007.0148     Document Type: Article
Times cited : (70)

References (49)
  • 2
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 3
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo RA: Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med 1999;131:281-303.
    • (1999) Ann Intern Med , vol.131 , pp. 281-303
    • DeFronzo, R.A.1
  • 4
    • 0031975069 scopus 로고    scopus 로고
    • The effects of improved glycemic control on complications in type 2 diabetes
    • Gaster B, Hirsch IB: The effects of improved glycemic control on complications in type 2 diabetes. Arch Intern Med 1998;158:134-140.
    • (1998) Arch Intern Med , vol.158 , pp. 134-140
    • Gaster, B.1    Hirsch, I.B.2
  • 6
    • 0012397405 scopus 로고    scopus 로고
    • Effects of American ginseng berry extract on blood glucose levels in ob/ob mice
    • Xie JT, Aung HH, Wu JA, Attele AS, Yuan CS: Effects of American ginseng berry extract on blood glucose levels in ob/ob mice. Am J Chin Med 2002;30:187-194.
    • (2002) Am J Chin Med , vol.30 , pp. 187-194
    • Xie, J.T.1    Aung, H.H.2    Wu, J.A.3    Attele, A.S.4    Yuan, C.S.5
  • 9
    • 0141726886 scopus 로고    scopus 로고
    • Pharmacists seek the solution of a shaman
    • Anhäuser M: Pharmacists seek the solution of a shaman. Drug Discov Today 2003;8:868-869.
    • (2003) Drug Discov Today , vol.8 , pp. 868-869
    • Anhäuser, M.1
  • 10
    • 0024398947 scopus 로고
    • Medicinal plants with hypoglycemic activity
    • Atta Ur R, Zaman K: Medicinal plants with hypoglycemic activity. J Ethnopharmacol 1989;26:1-55.
    • (1989) J Ethnopharmacol , vol.26 , pp. 1-55
    • Atta, U.R.1    Zaman, K.2
  • 11
    • 0027432773 scopus 로고
    • Protective effect of gypenosides against oxidative stress in phagocytes, vascular endothelial cells, and liver microsomes
    • Li L, Jiao L, Lau BH: Protective effect of gypenosides against oxidative stress in phagocytes, vascular endothelial cells, and liver microsomes. Cancer Biother 1993;8:263-272.
    • (1993) Cancer Biother , vol.8 , pp. 263-272
    • Li, L.1    Jiao, L.2    Lau, B.H.3
  • 12
    • 0027351284 scopus 로고
    • Evaluation of the anti-inflammatory and liver-protective effects of Anoectochilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats
    • Lin JM, Lin CC, Chiu HF, Yang JJ, Lee SG: Evaluation of the anti-inflammatory and liver-protective effects of Anoectochilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats. Am J Chin Med 1993;21:59-69.
    • (1993) Am J Chin Med , vol.21 , pp. 59-69
    • Lin, J.M.1    Lin, C.C.2    Chiu, H.F.3    Yang, J.J.4    Lee, S.G.5
  • 13
    • 1942486515 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects of crude saponin fractions from Panax ginseng and Gynostemma pentaphyllum
    • Jang YJ, Kim JK, Lee MS, Ham IH, Whang WK, Kim KH, Kim HJ: Hypoglycemic and hypolipidemic effects of crude saponin fractions from Panax ginseng and Gynostemma pentaphyllum. Yakhak Hoechi 2001;45:545-556.
    • (2001) Yakhak Hoechi , vol.45 , pp. 545-556
    • Jang, Y.J.1    Kim, J.K.2    Lee, M.S.3    Ham, I.H.4    Whang, W.K.5    Kim, K.H.6    Kim, H.J.7
  • 14
    • 0031671056 scopus 로고    scopus 로고
    • Zhou Z, Wang Y, Zhou Y, Zhang S: Effect of Gynostemma pentaphyllum Mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study. Chin Med J (Engl Ed) 1998;111:847-850.
    • Zhou Z, Wang Y, Zhou Y, Zhang S: Effect of Gynostemma pentaphyllum Mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study. Chin Med J (Engl Ed) 1998;111:847-850.
  • 15
    • 0001540794 scopus 로고
    • Alkaline cleavage of gypenosides and characterization of dammarane-type aglycones by gas chromatography-mass spectrometry
    • Kuwahara M, Kawanishi F, Komiya T, Ohshio H: Alkaline cleavage of gypenosides and characterization of dammarane-type aglycones by gas chromatography-mass spectrometry. Chem Pharm Bull 1989;37:135-139.
    • (1989) Chem Pharm Bull , vol.37 , pp. 135-139
    • Kuwahara, M.1    Kawanishi, F.2    Komiya, T.3    Ohshio, H.4
  • 16
    • 0020597067 scopus 로고
    • Studies on the constituents of Gynostemma pentaphyllum Makino. Structures of gypenoside I-XIV
    • Takemoto T, Arihara S, Nakajima T, Okuhara M: Studies on the constituents of Gynostemma pentaphyllum Makino. Structures of gypenoside I-XIV. Yakugaku Zasshi 1983;103:173-185.
    • (1983) Yakugaku Zasshi , vol.103 , pp. 173-185
    • Takemoto, T.1    Arihara, S.2    Nakajima, T.3    Okuhara, M.4
  • 19
    • 0017375321 scopus 로고
    • Report of the American Institute of Nutrition ad hoc Committee on Standards for Nutritional Studies
    • American Institute of Nutrition
    • American Institute of Nutrition: Report of the American Institute of Nutrition ad hoc Committee on Standards for Nutritional Studies. J Nutr 1977;107:1340-1348.
    • (1977) J Nutr , vol.107 , pp. 1340-1348
  • 20
    • 1642468898 scopus 로고
    • Report of Ad Hoc Committee on Standards for Nutritional Studies
    • American Institute of Nutrition
    • American Institute of Nutrition: Report of Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 1980;110:1717-1726.
    • (1980) J Nutr , vol.110 , pp. 1717-1726
  • 21
    • 0033654490 scopus 로고    scopus 로고
    • Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by CCl4 in rats
    • Chen JC, Tsai CC, Chen LD, Chen HH, Wang WC: Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by CCl4 in rats. Am J Chin Med 2000;28:175-185.
    • (2000) Am J Chin Med , vol.28 , pp. 175-185
    • Chen, J.C.1    Tsai, C.C.2    Chen, L.D.3    Chen, H.H.4    Wang, W.C.5
  • 22
    • 0033153773 scopus 로고    scopus 로고
    • Gynostemma pentaphyllum: Identification of major sapogenins and differentiation from Panax species
    • Cui JF, Eneroth P, Bruhn JG: Gynostemma pentaphyllum: identification of major sapogenins and differentiation from Panax species. Eur J Pharm Sci 1999;8:187-191.
    • (1999) Eur J Pharm Sci , vol.8 , pp. 187-191
    • Cui, J.F.1    Eneroth, P.2    Bruhn, J.G.3
  • 24
    • 0016405032 scopus 로고
    • A clinical evaluation of serum ferritin as an index of iron stores
    • Lipschitz DA, Cook JD, Finch CA: A clinical evaluation of serum ferritin as an index of iron stores. N Engl J Med 1974;290:1213-1216.
    • (1974) N Engl J Med , vol.290 , pp. 1213-1216
    • Lipschitz, D.A.1    Cook, J.D.2    Finch, C.A.3
  • 25
    • 0017300937 scopus 로고
    • Ferritin phenotypes: Structure and metabolism
    • Drysdale JW: Ferritin phenotypes: structure and metabolism. Ciba Found Symp 1976;51:41-67.
    • (1976) Ciba Found Symp , vol.51 , pp. 41-67
    • Drysdale, J.W.1
  • 27
    • 0015911095 scopus 로고
    • Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A
    • Hulcher FH, Oleson WH: Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. J Lipid Res 1973;14:625-631.
    • (1973) J Lipid Res , vol.14 , pp. 625-631
    • Hulcher, F.H.1    Oleson, W.H.2
  • 28
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 29
    • 0017067402 scopus 로고
    • Interaction of anions and divalent metal ions with phosphopyruvate carboxykinase
    • Bentle LA, Lardy HA: Interaction of anions and divalent metal ions with phosphopyruvate carboxykinase. J Biol Chem 1976;251:2916-2921.
    • (1976) J Biol Chem , vol.251 , pp. 2916-2921
    • Bentle, L.A.1    Lardy, H.A.2
  • 30
    • 0023683758 scopus 로고
    • Determination of glucose-6-phosphatase activity using the glucose dehydrogenase-coupled reaction
    • Alegre M, Ciudad CJ, Fillat C, Gulnovant JJ: Determination of glucose-6-phosphatase activity using the glucose dehydrogenase-coupled reaction. Anal Biochem 1988;173:185-189.
    • (1988) Anal Biochem , vol.173 , pp. 185-189
    • Alegre, M.1    Ciudad, C.J.2    Fillat, C.3    Gulnovant, J.J.4
  • 31
    • 0023154010 scopus 로고
    • Factors underlying significant underestimations of glucokinase activity in crude liver extracts: Physiological implications of higher cellular activity
    • Davidson AL, Arion WJ: Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity. Arch Biochem Biophys 1987;253:156-167.
    • (1987) Arch Biochem Biophys , vol.253 , pp. 156-167
    • Davidson, A.L.1    Arion, W.J.2
  • 33
    • 0025938575 scopus 로고
    • Characterization of CS-045, a new oral antidiabetic agent: II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice
    • Fujiwara T, Wada M, Fukuda K, Fukami M, Yoshioka S, Yoshioka T, Horikoshi H: Characterization of CS-045, a new oral antidiabetic agent: II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db mice. Metabolism 1991;40:1213-1218.
    • (1991) Metabolism , vol.40 , pp. 1213-1218
    • Fujiwara, T.1    Wada, M.2    Fukuda, K.3    Fukami, M.4    Yoshioka, S.5    Yoshioka, T.6    Horikoshi, H.7
  • 34
    • 0033842027 scopus 로고    scopus 로고
    • Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
    • Cavaghan MK, Ehrmann DA, Polonsky KS: Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest 2000;106:329-333.
    • (2000) J Clin Invest , vol.106 , pp. 329-333
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Polonsky, K.S.3
  • 36
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and type II diabetes
    • Saltiel AR, Olefsky JM: Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 1996;45:1661-1669.
    • (1996) Diabetes , vol.45 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 37
    • 0033744396 scopus 로고    scopus 로고
    • Rosiglitazone in the treatment of type 2 diabetes mellitus: A critical review
    • Malinowski JM, Bolesta S: Rosiglitazone in the treatment of type 2 diabetes mellitus: a critical review. Clin Ther 2000;22:1151-1168.
    • (2000) Clin Ther , vol.22 , pp. 1151-1168
    • Malinowski, J.M.1    Bolesta, S.2
  • 39
    • 0031898610 scopus 로고
    • PPAR-gamma: Adipogenic regulator and thiazolidinedione receptor
    • Spiegelman BM: PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 1988;47:507-514.
    • (1988) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 40
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995;270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 41
    • 0031888121 scopus 로고    scopus 로고
    • Consensus Development Conference on Insulin Resistance
    • American Diabetes Association
    • American Diabetes Association: Consensus Development Conference on Insulin Resistance. Diabetes Care 1998;21:310-314.
    • (1998) Diabetes Care , vol.21 , pp. 310-314
  • 47
    • 0023850224 scopus 로고
    • Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats
    • Iynedjian PB, Gjinovci A, Renold AE: Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats. J Biol Chem 1988;263:740-744.
    • (1988) J Biol Chem , vol.263 , pp. 740-744
    • Iynedjian, P.B.1    Gjinovci, A.2    Renold, A.E.3
  • 48
    • 0029005276 scopus 로고
    • Traditional Chinese medicine in treatment of hyperlipidaemia
    • Cour B, Molgaard P, Yi Z: Traditional Chinese medicine in treatment of hyperlipidaemia. J Ethnopharmacol 1995;46:125-129.
    • (1995) J Ethnopharmacol , vol.46 , pp. 125-129
    • Cour, B.1    Molgaard, P.2    Yi, Z.3
  • 49
    • 0037179551 scopus 로고    scopus 로고
    • Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells
    • Wang QF, Chen JC, Hsieh SJ, Cheng CC, Hsu SL: Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Cancer Lett 2002;183:169-178.
    • (2002) Cancer Lett , vol.183 , pp. 169-178
    • Wang, Q.F.1    Chen, J.C.2    Hsieh, S.J.3    Cheng, C.C.4    Hsu, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.