BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis?

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Velho, Sérgia ^a   Moutinho, Cátia ^a   Cirnes, Luís ^a   Albuquerque, Cristina ^b   Hamelin, Richard ^c   Schmitt, Fernando ^a,d   Carneiro, Fátima ^a,d,e   Oliveira, Carla ^a,d   Seruca, Raquel ^a,d  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

^c INSERM   (France)

^d University of Porto   (Portugal)

^e HOSPITAL DE SÃO JOÃO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BISULFITE; GENE PRODUCT; K RAS PROTEIN; NUCLEOTIDE; PROTEIN MLH1; PROTEIN PIK3CA; UNCLASSIFIED DRUG; BRAF PROTEIN, HUMAN; MICROSATELLITE DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN; PROTEIN P21;

ARTICLE; CLINICAL ARTICLE; COLON ADENOMA; COLON CARCINOGENESIS; COLON POLYP; COLORECTAL CARCINOMA; CPG ISLAND; DNA DETERMINATION; DNA METHYLATION; EPIGENETICS; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN TISSUE; MALIGNANT TRANSFORMATION; MICROSATELLITE INSTABILITY; MUTATIONAL ANALYSIS; ONCOGENE; PHENOTYPE; POLYMERASE CHAIN REACTION; TUMOR CLASSIFICATION; BIOLOGICAL MODEL; CARCINOMA; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; ONCOGENE RAS; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CARCINOMA; COLONIC POLYPS; COLORECTAL NEOPLASMS; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HUMANS; MICROSATELLITE REPEATS; MODELS, GENETIC; MUTATION; PHENOTYPE; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 53149097362     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-255     Document Type: Article

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