Development of an in vitro skin sensitization test based on ROS production in THP-1 cells

Toxicology in Vitro

Volumn 27, Issue 2, 2013, Pages 857-863

  Saito, Kazutoshi ^a   Miyazawa, Masaaki ^a   Nukada, Yuko ^a   Sakaguchi, Hitoshi ^a   Nishiyama, Naohiro ^a  

^a KAO CORPORATION   (Japan)

Author keywords

Animal testing alternatives; In vitro testing; Reactive oxygen species (ROS); Skin sensitization; THP 1 cells

Indexed keywords

DICHLORODIHYDROFLUORESCEIN DIACETATE; REACTIVE OXYGEN METABOLITE;

ACCURACY; ARTICLE; BIOASSAY; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; LEUKEMIA CELL LINE; LOCAL LYMPH NODE ASSAY; PREDICTION; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; BIOLOGICAL ASSAY; CELL LINE; CELL SURVIVAL; DERMATITIS, ALLERGIC CONTACT; HAPTENS; HUMANS; REACTIVE OXYGEN SPECIES; REPRODUCIBILITY OF RESULTS;

ANIMALIA;

EID: 84872737313     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.12.025     Document Type: Article

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