Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro

Toxicology in Vitro

Volumn 24, Issue 6, 2010, Pages 1803-1809

  Mitjans, M ^a   Galbiati, V ^b   Lucchi, L ^b   Viviani, B ^b   Marinovich, M ^b   Galli, C L ^b   Corsini, E ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Allergen potency; Alternative method; Cytokines; Dndritic cells; Hpersensitivity; In vitro toxicology

Indexed keywords

1,4 BENZOQUINONE; 2 AMINOPHENOL; ALLERGEN; CITRAL; GERMALL 115; INTERLEUKIN 8; ISOEUGENOL; LACTIC ACID; MALEIC ACID DIETHYL ESTER; MITOGEN ACTIVATED PROTEIN KINASE P38; PROPYLENE GLYCOL;

ALLERGY TEST; ARTICLE; CELL VIABILITY; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY TEST; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LOCAL LYMPH NODE ASSAY; NONHUMAN;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME ACTIVATION; GENE EXPRESSION; HUMANS; INTERLEUKIN-8; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, MESSENGER;

EID: 77956180476     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.06.001     Document Type: Article

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