Antigen-specific regulation of ige antibodies by non-antigen-specific gd t cells

Journal of Immunology

Volumn 190, Issue 3, 2013, Pages 913-921

  Huang, Yafei ^a   Aydintug, M Kemal ^a   Loomis, Joshua ^a   MacLeod, Megan K ^a   McKee, Amy S ^a   Kirchenbaum, Greg ^a   Jakubzick, Claudia V ^a   Kedl, Ross M ^a   Sun, Deming ^b   Jacobelli, Jordan ^a   O'Brien, Rebecca L ^a   Born, Willi K ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E ANTIBODY; LYSOZYME; OVALBUMIN;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ANTIGEN SPECIFICITY; ARTICLE; CELL LABELING; CONTROLLED STUDY; EGG; FEMALE; GAMMA DELTA T LYMPHOCYTE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VIVO STUDY; LYMPHOCYTE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL;

ADMINISTRATION, INHALATION; ADOPTIVE TRANSFER; AEROSOLS; ANIMALS; ANTIGENS; ASTHMA; CELL SEPARATION; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN E; IMMUNOLOGICAL SYNAPSES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MURAMIDASE; OVALBUMIN; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SPLEEN; T-CELL ANTIGEN RECEPTOR SPECIFICITY; T-LYMPHOCYTE SUBSETS;

EID: 84872719419     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202230     Document Type: Article

References (44)

1. Mowat, A. M. 1987. The regulation of immune responses to dietary protein antigens. Immunol. Today 8: 93-98.
2. McMenamin, C., and P. G. Holt. 1993. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T celldependent immune deviation resulting in selective suppression of immunoglobulin E production. J. Exp. Med. 178: 889-899. (Pubitemid 23260426)
3. Frew, A. J. 2010. Allergen immunotherapy. J. Allergy Clin. Immunol. 125(Suppl. 2): S306-S313.
4. Shirinbak, S., Y. A. Taher, H.Maazi, R. Gras, B. C. A. M. van Esch, P. A. J. Henricks, J. N. Samsom, J. S. Verbeek, B. N. Lambrecht, A. J. M. van Oosterhout, and M. C. Nawijn. 2010. Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice. J. Immunol. 185: 3857-3865.
5. Seymour, B. W. P., L. J. Gershwin, and R. L. Coffman. 1998. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-g/d+ T cells or interferon (IFN)-g in a murine model of allergen sensitization. J. Exp. Med. 187: 721-731. (Pubitemid 28115188)
6. Campbell, D. J., and M. A. Koch. 2011. Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat. Rev. Immunol. 11: 119-130.
7. McMenamin, C., C. Pimm, M. McKersey, and P. G. Holt. 1994. Regulation of IgE responses to inhaled antigen in mice by antigen-specific g d T cells. Science 265: 1869-1871. (Pubitemid 24324243)
8. Huang, Y., N. Jin, C. L. Roark, M. K. Aydintug, J. M. Wands, H. Huang, R. L. O'Brien, and W. K. Born. 2009. The influence of IgE-enhancing and IgEsuppressive gammadelta T cells changes with exposure to inhaled ovalbumin. J. Immunol. 183: 849-855.
9. Harrison, L. C., M. Dempsey-Collier, D. R. Kramer, and K. Takahashi. 1996. Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes. J. Exp. Med. 184: 2167-2174.
10. Bonneville, M., R. L. O'Brien, and W. K. Born. 2010. Gammadelta T cell effector functions: A blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10: 467-478.
11. Chien, Y.-H., R. Jores, and M. P. Crowley. 1996. Recognition by g/d T cells. Annu. Rev. Immunol. 14: 511-532.
12. Brandes, M., K. Willimann, and B. Moser. 2005. Professional antigenpresentation function by human gammadelta T cells. Science 309: 264-268. (Pubitemid 40967855)
13. Cheng, L., Y. Cui, H. Shao, G. Han, L. Zhu, Y. Huang, R. L. O'Brien, W. K. Born, H. J. Kaplan, and D. Sun. 2008. Mouse gammadelta T cells are capable of expressing MHC class II molecules, and of functioning as antigenpresenting cells. J. Neuroimmunol. 203: 3-11.
14. Lahn, M., A. Kanehiro, K. Takeda, A. Joetham, J. Schwarze, G. Kohler, R. O'Brien, E. W. Gelfand, and W. Born. 1999. Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells. [Published erratum appears in 2000 Nat. Med. 6: 229.] Nat. Med. 5: 1150-1156. (Pubitemid 29474419)
15. Zuany-Amorim, C., C. Ruffié, S. Hailé, B. B. Vargaftig, P. Pereira, and M. Pretolani. 1998. Requirement for gammadelta T cells in allergic airway inflammation. Science 280: 1265-1267.
16. Huber, S. A., D. Graveline, M. K. Newell, W. K. Born, and R. L. O'Brien. 2000. V g 1+ T cells suppress and V g 4+ T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice. J. Immunol. 165: 4174-4181.
17. Hahn, Y.-S., C. Taube, N. Jin, L. Sharp, J. M. Wands, M. K. Aydintug, M. Lahn, S. A. Huber, R. L. O'Brien, E. W. Gelfand, and W. K. Born. 2004. Different potentials of g d T cell subsets in regulating airway responsiveness: V g 1+ cells, but not V g 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. J. Immunol. 172: 2894-2902. (Pubitemid 38263675)
18. Russano, A. M., E. Agea, L. Corazzi, A. D. Postle, G. De Libero, S. A. Porcelli, F. M. de Benedictis, and F. Spinozzi. 2006. Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J. Allergy Clin. Immunol. 117: 1178-1184.
19. Born, W. K., Y. Huang, N. Jin, H. Huang, and R. L. O'Brien. 2010. Balanced approach of gammadelta T cells to type 2 immunity. Immunol. Cell Biol. 88: 269-274.
20. Stahl, P., P. H. Schlesinger, E. Sigardson, J. S. Rodman, and Y. C. Lee. 1980. Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling. Cell 19: 207-215. (Pubitemid 10154225)
21. Bensch, K. G., E. Dominguez, and A. A. Liebow. 1967. Absorption of intact protein molecules across the pulmonary air-tissue barrier. Science 157: 1204-1206.
22. Kim, K.-J., and A. B. Malik. 2003. Protein transport across the lung epithelial barrier. Am. J. Physiol. Lung Cell. Mol. Physiol. 284: L247-L259. (Pubitemid 36164359)
23. Mebius, R. E., and G. Kraal. 2005. Structure and function of the spleen. Nat. Rev. Immunol. 5: 606-616. (Pubitemid 41113192)
24. Jin, N., C. Taube, L. Sharp, Y.-S. Hahn, X. Yin, J. M. Wands, C. L. Roark, R. L. O'Brien, E. W. Gelfand, and W. K. Born. 2005. Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness. J. Immunol. 174: 2671-2679. (Pubitemid 40279681)
25. Heilig, J. S., and S. Tonegawa. 1986. Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature 322: 836-840. (Pubitemid 16055256)
26. Lyons, A. B. 1999. Divided we stand: Tracking cell proliferation with carboxyfluorescein diacetate succinimidyl ester. Immunol. Cell Biol. 77: 509-515.
27. Schindelin, J., I. Arganda-Carreras, E. Frise, V. Kaynig, M. Longair, T. Pietzsch, S. Preibisch, C. Rueden, S. Saalfeld, B. Schmid, et al. 2012. Fiji: An open-source platform for biological-image analysis. Nat. Methods 9: 676-682.
28. Hill, S. W., D. E. Kipp, I. Melchers, J. A. Frelinger, and E. E. Sercarz. 1980. Multiple H-2 and non-H-2 genes controlling the antilysozyme response: Alternative gene constellations can lead to responsiveness. Eur. J. Immunol. 10: 384-391. (Pubitemid 10062918)
29. Gould, H. J., and B. J. Sutton. 2008. IgE in allergy and asthma today. Nat. Rev. Immunol. 8: 205-217. (Pubitemid 351323292)
30. Pabst, R. 1988. The spleen in lymphocyte migration. Immunol. Today 9: 43-45. (Pubitemid 18037797)
31. Rubtsov, A. V., K. Rubtsova, A. Fischer, R. T. Meehan, J. Z. Gillis, J. W. Kappler, and P. Marrack. 2011. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity. Blood 118: 1305-1315.
32. Drutman, S. B., J. C. Kendall, and E. S. Trombetta. 2012. Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells. J. Immunol. 188: 3603-3610.
33. Su, S. B., P. B. Silver, R. S. Grajewski, R. K. Agarwal, J. Tang, C. C. Chan, and R. R. Caspi. 2005. Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity. J. Immunol. 175: 6303-6310. (Pubitemid 41598869)
34. Krummen, M., S. Balkow, L. Shen, S. Heinz, C. Loquai, H. C. Probst, and S. Grabbe. 2010. Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy. J. Leukoc. Biol. 88: 189-199.
35. Daro, E., B. Pulendran, K. Brasel, M. Teepe, D. Pettit, D. H. Lynch, D. Vremec, L. Robb, K. Shortman, H. J. McKenna, et al. 2000. Polyethylene glycol-modified GM-CSF expands CD11b(high)CD11c(high) but not CD11b(low)CD11c(high) murine dendritic cells in vivo: A comparative analysis with Flt3 ligand. J. Immunol. 165: 49-58. (Pubitemid 30429489)
36. Herman, A., J. W. Kappler, P. Marrack, and A. M. Pullen. 1991. Superantigens: Mechanism of T-cell stimulation and role in immune responses. Annu. Rev. Immunol. 9: 745-772.
37. Young, L. J., N. S. Wilson, P. Schnorrer, A. Mount, R. J. Lundie, N. L. La Gruta, B. S. Crabb, G. T. Belz, W. R. Heath, and J. A. Villadangos. 2007. Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens. Proc. Natl. Acad. Sci. USA 104: 17753-17758. (Pubitemid 350210907)
38. Espinosa, E., J. Tabiasco, D. Hudrisier, and J. J. Fournié. 2002. Synaptic transfer by human g d T cells stimulated with soluble or cellular antigens. J. Immunol. 168: 6336-6343. (Pubitemid 34620056)
39. Wakim, L. M., and M. J. Bevan. 2011. Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection. Nature 471: 629-632.
40. Cook, L., N. Miyahara, N. Jin, J. M. Wands, C. Taube, C. L. Roark, T. A. Potter, E. W. Gelfand, R. L. O'Brien, and W. K. Born. 2008. Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness. J. Immunol. 181: 309-319.
41. Gutgemann, I., A. M. Fahrer, J. D. Altman, M. M. Davis, and Y.-H. Chien. 1998. Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity 8: 667-673. (Pubitemid 28294513)
42. Gutgemann, I., J. M. Darling, H. B. Greenberg, M. M. Davis, and Y.-H. Chien. 2002. A blood-borne antigen induces rapid T-B cell contact: A potential mechanism for tolerance induction. Immunology 107: 420-425. (Pubitemid 36693646)
43. Belz, G. T., C. M. Smith, L. Kleinert, P. Reading, A. Brooks, K. Shortman, F. R. Carbone, and W. R. Heath. 2004. Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc. Natl. Acad. Sci. USA 101: 8670-8675. (Pubitemid 38745829)
44. Allan, R. S., J. Waithman, S. Bedoui, C. M. Jones, J. A. Villadangos, Y. Zhan, A. M. Lew, K. Shortman, W. R. Heath, and F. R. Carbone. 2006. Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. Immunity 25: 153-162. (Pubitemid 44066832)