Vertical inhibition of the PI3K/Akt/mTOR pathway for the treatment of osteoarthritis

Journal of Cellular Biochemistry

Volumn 114, Issue 2, 2013, Pages 245-249

  Chen, Jiezhong ^a,b   Crawford, Ross ^a   Xiao, Yin ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Autophagy; Extracellular matrix metalloproteinases; Osteoarthritis; PI3K AKT pathway

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MATRIX METALLOPROTEINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RAPAMYCIN;

AUTOPHAGY; CARTILAGE CELL; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

AUTOPHAGY; CELL PROLIFERATION; EXTRACELLULAR MATRIX; HUMANS; MOLECULAR TARGETED THERAPY; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; OSTEOARTHRITIS; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84872710561     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24362     Document Type: Review

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