mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands

Biotechnology and Bioengineering

Volumn 110, Issue 3, 2013, Pages 857-870

  Menegatti, Stefano ^a   Hussain, Mahmud ^a   Naik, Amith D ^a   Carbonell, Ruben G ^a,b   Rao, Balaji M ^a  

^a North Carolina State University   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Affinity ligand; Cyclic peptide; Fc binding; Library; MRNA display

Indexed keywords

AFFINITY LIGANDS; BASIC CONDITIONS; CHROMATOGRAPHIC RESINS; COMPLEX MIXTURE; CROSSLINKING REACTION; CYCLIC PENTAPEPTIDES; CYCLIC PEPTIDES; FAB FRAGMENTS; FC BINDING; HIGH YIELD; HUMAN IMMUNOGLOBULIN; LINEAR PEPTIDES; MAMMALIAN SPECIES; MONOCLONAL ANTIBODIES (MABS); MRNA-DISPLAY; NO BINDING; PRIMARY AMINE GROUPS; PROTEIN A; SOLID PHASE PEPTIDE SYNTHESIS; SOLID PHASE SYNTHESIS; SOLID-PHASE; TARGETS OF INTEREST;

CHELATION; CHROMATOGRAPHY; CYCLIZATION; LIBRARIES; MAMMALS; MONOCLONAL ANTIBODIES; PEPTIDES; RESINS;

LIGANDS;

AMINE; CYCLOPEPTIDE; FC RECEPTOR; IMMUNOGLOBULIN G; MESSENGER RNA; RESIN;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHROMATOGRAPHY; CROSS LINKING; CYCLIZATION; LIGAND BINDING; PEPTIDE LIBRARY; PEPTIDE SYNTHESIS; PROTEIN PURIFICATION; SOLID PHASE SYNTHESIS;

HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN ENGINEERING; RNA, MESSENGER; SOLID-PHASE SYNTHESIS TECHNIQUES;

MAMMALIA;

EID: 84872657954     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24760     Document Type: Article

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