Synthesis and screening of a cyclic peptide library: Discovery of small-molecule ligands against human prolactin receptor

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 3, 2009, Pages 1026-1033

  Liu, Tao ^a   Joo, Sang Hoon ^a   Voorhees, Jeffrey L ^a   Brooks, Charles L ^a   Pei, Dehua ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Combinatorial library; Cyclic peptides; Partial Edman degradation; Prolactin; Prolactin receptor

Indexed keywords

CYCLOPEPTIDE; LIGAND; PEPTIDE LIBRARY; PROLACTIN; PROLACTIN RECEPTOR; PROLACTIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; HUMAN; MOLECULAR PROBE; NONHUMAN; PROLACTINOMA; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION;

AMINO ACID SEQUENCE; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; LIGANDS; MICROSPHERES; PEPTIDE LIBRARY; PEPTIDES; PEPTIDES, CYCLIC; RECEPTORS, PROLACTIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SURFACE PLASMON RESONANCE;

EID: 58949090838     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.01.015     Document Type: Article

References (38)

1. Wipf P. Chem. Rev. 95 (1995) 2115
2. Hamada Y., and Shioiri T. Chem. Rev. 105 (2005) 4441
3. Pomilio A.B., Battista M.E., and Vitale A.A. Curr. Org. Chem. 10 (2006) 2075
4. Laupacis A., Keown P.A., Ulan R.A., McKenzie N., and Stiller C.R. Can. Med. Assoc. J. 126 (1982) 1041
5. Kirkpatrick P., Raja A., LaBonte J., and Lebbos J. Nat. Rev. Drug. Discov. 2 (2003) 943
6. Sandhu P., Xu X., Bondiskey P.J., Balani S.K., Morris M.L., Tang Y.S., Miller A.R., and Pearson P.G. Antimicrob. Agents Chemother. 48 (2004) 1272
7. Kohli R.M., Walsh C.T., and Burkart M.D. Nature 418 (2002) 658
8. Nguyen K.T., Ritz D., Gu J.-Q., Alexander D., Chu M., Miao V., Brian P., and Baltz R.H. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 17462
9. Qin C., Bu X., Zhong X., Ng N.L.J., and Guo Z. J. Comb. Chem. 6 (2004) 398
10. Xiao Q., and Pei D. J. Med. Chem. 50 (2007) 3132
11. Fernandez-Lopez S., Kim H.S., Choi E.C., Delgado M., Granja J.R., Khasanov A., Kraehenbuehl K., Long G., Weinberger D.A., Wilcoxen K.M., and Ghadiri M.R. Nature 412 (2001) 452
12. Frecer V., Ho B., and Ding J.L. Antimicrob. Agents Chemother. 48 (2004) 3349
13. Monroc S., Badosa E., Feliu L., Planas M., Montesinos E., and Bardaji{dotless}́ E. Peptides 27 (2006) 2567
14. Giebel L.B., Cass R.T., Milligan D.L., Young D.C., Arze R., and Johnson C.R. Biochemistry 34 (1995) 15430
15. Krook M., Lindbladh C., Eriksen J.A., and Mosbach K. Mol. Divers. 3 (1998) 149
16. Czompoly T., Labadi A., Balazs M., Nemeth P., and Balogh P. Biochem. Biophys. Res. Commun. 307 (2003) 791
17. Meyer S.C., Gaj T., and Ghosh I. Chem. Bio. Drug Des. 68 (2006) 3
18. Tavassoli A., and Benkovic S.J. Angew. Chem., Int. Ed. 44 (2005) 2760
19. Kinsella T.M., Ohashi C.T., Harder A.G., Yam G.C., Li W., Peelle B., Pali E.S., Bennett M.K., Molineaux S.M., Anderson D.A., Masuda E.S., and Payan D.G. J. Biol. Chem. 277 (2002) 37512
20. Millward S.W., Fiacco S., Austin R.J., and Roberts R.W. ACS Chem. Bio. 2 (2007) 625
21. Millward S.W., Takahashi T.T., and Roberts R.W. J. Am. Chem. Soc. 127 (2005) 14142
22. Lam K.S., Salmon S.E., Hersh E.M., Hruby V.J., Kazmierski W.M., and Knapp R.J. Nature 354 (1991) 82
23. Houghten R.A., Pinilla C., Blondelle S.E., Appel J.R., Dooley C.T., and Cuervo J.H. Nature 354 (1991) 84
24. Eichler J., Lucka A.W., Pinilla C., and Houghten R.A. Mol. Divers. 1 (1996) 233
25. Zang X., Yu Z., and Chu Y.-H. Bioorg. Med. Chem. Lett. 8 (1998) 2327
26. Joo S.H., Xiao Q., Ling Y., Gopishetty B., and Pei D.H. J. Am. Chem. Soc. 128 (2006) 13000
27. Thakkar A., Wavreille A.S., and Pei D.H. Anal. Chem. 78 (2006) 5935
28. Goffin V., Bernichtein S., Tourine P., and Kelly P.A. Endocr. Rev. 26 (2005) 400
29. Clevenger C.V., Furth P.A., Hankinson S.E., and Schuler L.A. Endocr. Rev. 24 (2003) 1
30. Jomain J.B., Tallet E., Broutin I., Hoos S., van Agthoven J., Ducruix A., Kelly P.A., Kragelund B.B., England P., and Goffin V. J. Biol. Chem. 282 (2007) 33118
31. Liu R., Marik J., and Lam K.S. J. Am. Chem. Soc. 124 (2002) 7678
32. Sweeney M.C., Wavreille A.-S., Park J., Butchar J., Tridandapani S., and Pei D. Biochemistry 44 (2005) 14932
33. Somers W., Ultsch M., De Vos A.M., and Kossiakoff A.A. Nature 372 (1994) 478
34. Kinet S., Goffin V., Mainfroid V., and Martial J.A. J. Biol. Chem. 271 (1996) 14353
35. Sivaprasad U., Canfield J.M., and Brooks C.L. Biochemistry 43 (2004) 13755
36. Peterson F.C., Anderson P.J., Berliner L.J., and Brooks C.L. Protein Expr. Purif. 15 (1999) 16
37. Vojkovsky T. Pep. Res. 8 (1995) 236
38. Wilkins M.R., Gasteiger E., Bairoch A., Sanchez J.C., Williams K.L., Appel R.D., and Hochstrasser D.F. Methods Mol. Biol. 112 (1999) 531