Rational Design of a Peptide Agonist that Interacts Selectively with the Orphan Receptor, Bombesin Receptor Subtype 3

Journal of Biological Chemistry

Volumn 276, Issue 12, 2001, Pages 9219-9229

  Mantey, Samuel A ^a   Coy, David H ^b   Pradhan, Tapas K ^a   Igarashi, Hisato ^a   Rizo, Ivania M ^a   Shen, Lin ^a   Hou, Wei ^a   Hocart, Simon J ^b   Jensen, Robert T ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; BIOSYNTHESIS; MOLECULAR BIOLOGY; NEUROLOGY; PATHOLOGY; POLYPEPTIDES;

PEPTIDE DESIGN; PHARMACOLOGY;

BIOCHEMISTRY;

AMINO 3 PHENYLPROPIONIC ACID; AMINO ACID; BOMBESIN RECEPTOR; BOMBESIN RECEPTOR 3; DEXTRO TYROSYL BETA ALANYLPHENYLALANYLNITROLEUCINE BOMBESIN[6-14]; GASTRIN RELEASING PEPTIDE; GASTRIN RELEASING PEPTIDE RECEPTOR; GASTROINTESTINAL HORMONE; INOSITOL PHOSPHATE; LIGAND; MEMBRANE RECEPTOR; NEUROMEDIN B; NEUROMEDIN B RECEPTOR; NEUROTRANSMITTER; ORPHAN RECEPTOR; PEPTIDE AGONIST; PEPTIDE DERIVATIVE; PHENYLALANINE DERIVATIVE; PHOSPHOLIPASE C; PROPIONIC ACID DERIVATIVE; TRITIUM; UNCLASSIFIED DRUG; BOMBESIN RECEPTOR SUBTYPE 3; PEPTIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CENTRAL NERVOUS SYSTEM; CHIRALITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; GASTROINTESTINAL TRACT; GENE DISRUPTION; GLUCOSE HOMEOSTASIS; HYPERTENSION; MOLECULAR MODEL; NONHUMAN; OBESITY; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TECHNIQUE; ANIMAL; BAGG ALBINO MOUSE; CELL STRAIN 3T3; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG POTENTIATION; METABOLISM; MOUSE;

ANIMALIA; BOVINE RESPIRATORY SYNCYTIAL VIRUS; MAMMALIA;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; DRUG DESIGN; LIGANDS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PEPTIDES; RECEPTORS, BOMBESIN;

EID: 0035937737     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008737200     Document Type: Article

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