A Lectin with Highly Potent Inhibitory Activity toward Breast Cancer Cells from Edible Tubers of Dioscorea opposita cv. Nagaimo

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Chan, Yau Sang ^a   Ng, Tzi Bun ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSE; LACTOSE; LECTIN; RAFFINOSE;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DIOSCOREA OPPOSITA; DRUG POTENCY; DRUG PURIFICATION; DRUG STABILITY; ENZYME ACTIVITY; ENZYME SPECIFICITY; FLOW CYTOMETRY; HEMAGGLUTINATION; HUMAN; HUMAN CELL; IC 50; MEMBRANE DEPOLARIZATION; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE HOMOLOGY; THERMOSTABILITY;

AMINO ACID SEQUENCE; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, ION EXCHANGE; DIOSCOREA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; GALACTOSE; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; MCF-7 CELLS; MOLECULAR WEIGHT; PHOSPHATIDYLSERINES; PLANT LECTINS; PLANT TUBERS; PLANTS, EDIBLE; PROTEIN BINDING; PROTEIN STABILITY; SEQUENCE ANALYSIS, PROTEIN; TEMPERATURE;

DIOSCOREA POLYSTACHYA;

EID: 84872647584     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054212     Document Type: Article

References (58)

1. Subramanyam S, Smith DF, Clemens JC, Webb MA, Sardesai N, et al. (2008) Functional characterization of HFR1, a high-mannose N-glycan-specific wheat lectin induced by Hessian fly larvae. Plant Physiol 147: 1412-1426.
2. Naeem A, Ahmad E, Ashraf MT, Khan RH, (2007) Purification and characterization of mannose/glucose-specific lectin from seeds of Trigonella foenumgraecum. Biochemistry (Mosc) 72: 44-48.
3. Tsivileva OM, Nikitina VE, Loshchinina EA, (2007) Isolation and characterization of Lentinus edodes (Berk.) singer extracellular lectins. Biochemistry (Mosc) 73: 1154-1161.
4. Ellgaard L, Frickel EM, (2003) Calnexin, calreticulin, and ERp57: teammates in glycoprotein folding. Cell Biochem Biophys 39: 223-247.
5. Vasta GR, (2012) Galectins as pattern recognition receptors: structure, function, and evolution. Adv Exp Med Biol 946: 21-36.
6. Angata T, Brinkman-Van der Linden E, (2002) I-type lectins. Biochim Biophys Acta 1572: 294-316.
7. Zelensky AN, Gready JE, (2005) The C-type lectin-like domain superfamily. FEBS J 272: 6179-6217.
8. Peumans WJ, Van Damme EJ, (1998) Plant lectins: specific tools for the identification, isolation, and characterization of O-linked glycans. Crit Rev Biochem Mol Biol 33: 209-258.
9. Van Damme EJ, Lannoo N, Peumans WJ, (2008) Plant lectins. Adv Bot 48: 107-209.
10. Lannoo N, Van Damme EJ, (2010) Nucleocytoplasmic plant lectins. Biochim Biophys Acta 1800: 190-201.
11. Cardoso MR, Mota CM, Ribeiro DP, Santiago FM, Carvalho JV, et al. (2011) ArtinM, a D-mannose-binding lectin from Artocarpus integrifolia, plays a potent adjuvant and immunostimulatory role in immunization against Neospora caninum. Vaccine 29: 9183-9193.
12. Lee CH, Kim JK, Kim HY, Park SM, Lee SM, (2009) Immunomodulating effects of Korean mistletoe lectin in vitro and in vivo. Int Immunopharmacol 9: 1555-1561.
13. Fu LL, Zhou CC, Yao S, Yu JY, Liu B, et al. (2011) Plant lectins: targeting programmed cell death pathways as antitumor agents. Int J Biochem Cell Biol 43: 1442-1449.
14. Feng L, Sun H, Zhang Y, Li DF, Wang DC, (2010) Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen. FASEB J 24: 3861-3868.
15. He X, Zhang Y, Yu F, Yu Z, (2011) A novel sialic acid binding lectin with anti-bacterial activity from the Hong Kong oyster (Crassostrea hongkongensis). Fish Shellfish Immunol 31: 1247-1250.
16. Toledo RG, Da Silva WD, Calich VL, Kipnis TL, (2010) Mannose-binding lectin complement pathway plays a key role in complement activation by Paracoccidioides brasiliensis. Mol Immunol 48: 26-36.
17. Ashraf GM, Banu N, Ahmad A, Singh LP, Kumar R, (2011) Purification, characterization, sequencing and biological chemistry of galectin-1 purified from Capra hircus (goat) heart. Protein J 30: 39-51.
18. Ola MS, Tabish M, Khan FH, Banu N, (2007) Purification and some properties of galectin-1 derived from water buffalo (Bubalus bubalis) brain. Cell Biol Int 31: 578-585.
19. Wojcikowski K, Wohlmuth H, Johnson DW, Gobe G, (2008) Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways. Food Chem Toxicol 46: 3122-3131.
20. Bhandari MR, Kawabata J, (2005) Bitterness and toxicity in wild yam (Dioscorea spp.) tubers of Nepal. Plant Foods Hum Nutr 60: 129-135.
21. Poon TY, Ong KL, Cheung BM, (2011) Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications. J Diabetes 3: 184-200.
22. Yagi F, Iwaya T, Haraguchi T, Goldstein IJ, (2002) The lectin from leaves of Japanese cycad, Cycas revoluta Thunb. (gymnosperm) is a member of the jacalin-related family. Eur J Biochem 269: 4335-4341.
23. Laemmli UK, Favre M, (1973) Gel electrophoresis of proteins. J Mol Biol 80: 575-599.
24. Nakagawa R, Yasokawa D, Ikeda T, Nagashima K, (1996) Purification and characterization of two lectins from calllus of Helianthus tuberosus. Biosci Biotechnol Biochem 60: 259-262.
25. Edman P, (1950) Method for determination of amino acid sequences in peptides, Acta Chem. Scand 28: 283-293.
26. Koike T, Beppu H, Kuzuya H, Maruta K, Shimpo K, et al. (1995) A 35 kDa mannose-binding lectin with hemagglutinating and mitogenic activities from "Kidachi Aloe" (Aloe arborescens Miller var. natalensis Berger). J Biochem 118: 1205-1210.
27. Lam SK, Ng TB, (2010) First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells. Biosci Rep 30: 307-317.
28. Yan Q, Li Y, Jiang Z, Sun Y, Zhu L, et al. (2009) Antiproliferation and apoptosis of human tumor cell lines by a lectin (AMML) of Astragalus mongholicus. Phytomedicine 16: 586-593.
29. Xu Z, Chen X, Zhang Q, Chen L, Wang Y, (2011) Corydalis yanhusuo W.T. Wang extract inhibits MCF-7 cell proliferation by inducing cell cycle G2/M arrest. Am J Chin Med 39: 579-586.
30. McAnuff MA, Omoruyi FO, Sotelo-López A, Asemota HN, (2005) Proximate analysis and some antinutritional factor constituents in selected varieties of Jamaican yams (Dioscorea and Rajana spp.). Plant Foods Hum Nutr 60: 93-98.
31. Shewry PR, (2003) Tuber storage proteins. Ann Bot 91: 755-769.
32. Gaidamashvili M, Ohizumi Y, Iijima S, Takayama T, Ogawa T, et al. (2004) Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities. J Biol Chem 279: 26028-26035.
33. Ohizumi Y, Gaidamashvili M, Ohwada S, Matsuda K, Kominami J, et al. (2009) Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae). J Agric Food Chem 57: 2896-2902.
34. Fang EF, Lin P, Wong JH, Tsao SW, Ng TB, (2010) A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean. J Agric Food Chem 58: 2221-2229.
35. Xia L, Ng TB, (2006) A hemagglutinin with mitogenic activity from dark red kidney beans. J Chromatogr B Analyt Technol Biomed Life Sci 844: 213-216.
36. Xia L, Ng TB, (2005) An antifungal protein from flageolet beans. Peptides 26: 2397-2403.
37. Sharma A, Wong JH, Lin P, Chan YS, Ng TB, (2010) Purification and characterization of a lectin from the Indian cultivar of French bean seeds. Protein Pept Lett 17: 221-227.
38. Ye XY, Wang HX, Ng TB, (1999) First chromatographic isolation of an antifungal thaumatin-like protein from French bean legumes and demonstration of its antifungal activity. Biochem Biophys Res Commun 263: 130-134.
39. Ye XY, Ng TB, (2002) Isolation of a novel peroxidase from French bean legumes and first demonstration of antifungal activity of a non-milk peroxidase. Life Sci 71: 1667-1680.
40. Hsu HC, Hsu CI, Lin RH, Kao CL, Lin JY, (1999) Fip-vvo, a new fungal immunomodulatory protein isolated from Volvariella volvacea. Biochem J 323: 557-565.
41. She QB, Ng TB, Liu WK, (1998) A novel lectin with potent immunomodulatory activity isolated from both fruiting bodies and cultured mycelia of the edible mushroom Volvariella volvacea. Biochem Biophys Res Commun 247: 106-111.
42. Salatino M, Rabinovich GA, (2011) Fine-tuning antitumor responses through the control of galectin-glycan interactions: an overview. Methods Mol Biol 677: 355-374.
43. Kobayashi T, Kuroda J, Ashihara E, Oomizu S, Terui Y, et al. (2010) Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways. Leukemia 24: 843-850.
44. Yang RY, Rabinovich GA, Liu FT, (2008) Galectins: structure, function and therapeutic potential. Expert Rev Mol Med 10: e17.
45. Carvalho FC, Soares SG, Tamarozzi MB, Rego EM, Roque-Barreira MC, (2011) The recognition of N-glycans by the lectin ArtinM mediates cell death of a human myeloid leukemia cell line. PLoS One 6: e27892.
46. Yang Y, Xu HL, Zhang ZT, Liu JJ, Li WW, et al. (2011) Characterization, molecular cloning, and in silico analysis of a novel mannose-binding lectin from Polygonatum odoratum (Mill.) with anti-HSV-II and apoptosis-inducing activities. Phytomedicine 18: 748-755.
47. Omokawa Y, Miyazaki T, Walde P, Akiyama K, Sugahara T, et al. (2010) In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin. Int J Pharm 389: 157-167.
48. Wong JH, Ng TB, (2005) Isolation and characterization of a glucose/mannose/rhamnose-specific lectin from the knife bean Canavalia gladiata. Arch Biochem Biophys 439: 91-98.
49. Kheeree N, Sangvanich P, Puthong S, Karnchanatat A, (2010) Antifungal and antiproliferative activities of lectin from the rhizomes of Curcuma amarissima Roscoe. Appl Biochem Biotechnol 162: 912-925.
50. Amano K, Katayama H, Saito A, Ando A, Nagata Y, (2012) Aleuria aurantia lectin exhibits antifungal activity against Mucor racemosus. Biosci Biotechnol Biochem 76: 967-970.
51. Nawrot R, Wolun-Cholewa M, Bialas W, Wyrzykowska D, Balcerkiewicz S, et al. (2010) Cytotoxic activity of proteins isolated from extracts of Corydalis cava tubers in human cervical carcinoma HeLa cells. BMC Complement Altern Med. 10: 78.
52. Kaur M, Singh K, Rup PJ, Saxena AK, Khan RH, et al. (2006) A tuber lectin from Arisaema helleborifolium Schott with anti-insect activity against melon fruit fly, Bactrocera cucurbitae (Coquillett) and anti-cancer effect on human cancer cell lines. Arch Biochem Biophys. 445: 156-165.
53. Fang EF, Ng TB, Shaw PC, Wong RN, (2011) Recent progress in medicinal investigations on trichosanthin and other ribosome inactivating proteins from the plant genus Trichosanthes. Curr Med Chem 18: 4410-4417.
54. Li T, Yin X, Liu D, Ma X, Lv H, et al. (2010) Isolation and characterization of a novel lectin with antifungal and antiproliferative activities from Sophora alopecuroides seeds. Acta Biochim Biophys Sin (Shanghai) 44: 606-613.
55. Lam SK, Ng TB, (2010) First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells. Biosci Rep 30: 307-317.
56. Saekoo J, Dechsukum C, Graidist P, Itharat A, (2010) Cytotoxic effect and its mechanism of dioscorealide B from Dioscorea membranacea against breast cancer cells. J Med Assoc Thai 93: 277-282.
57. Guo S, Liu M, Gonzalez-Perez RR, (2011) Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta 1815: 197-213.
58. Forouzanfar MH, Foreman KJ, Delossantos AM, Lozano R, Lopez AD, et al. (2011) Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis. Lancet 378: 1461-1484.Figure Legends.