Antiproliferation and apoptosis of human tumor cell lines by a lectin (AMML) of Astragalus mongholicus

Phytomedicine

Volumn 16, Issue 6-7, 2009, Pages 586-593

  Yan, Qiaojuan ^a   Li, Yanxia ^a   Jiang, Zhengqiang ^a   Sun, Yan ^b   Zhu, Lifen ^a   Ding, Zufeng ^b  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b BEIHANG UNIVERSITY   (China)

Author keywords

Antitumor; Apoptosis; Astragalus mongholicus; Cell cycle arrest; Cell proliferation; Lectin

Indexed keywords

ANTINEOPLASTIC AGENT; ASTRAGALUS EXTRACT; ASTRAGALUS MONGHOLICUS EXTRACT; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; PLANT LECTIN; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTRAGALUS MONGHOLICUS; ASTRAGALUS PLANT; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL MEMBRANE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG PURIFICATION; FEMALE; FLOW CYTOMETRY; FRAGMENTATION REACTION; HELA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; OSTEOBLAST; PRIORITY JOURNAL; STAINING; TUMOR CELL LINE;

AMINO ACID SEQUENCE; APOPTOSIS; ASTRAGALUS PLANT; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LECTINS; MOLECULAR SEQUENCE DATA;

ASTRAGALUS MONGHOLICUS;

EID: 67349227379     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.12.024     Document Type: Article

References (34)

1. Absar N., Yeasmin T., Raza M.S., Sarkar S.K., and Arisaka F. Single step purification, characterization and N-terminal sequences of a mannose specific lectin from mulberry seeds. Protein J. 24 (2005) 369-377
2. Büssing A., and Schietzel M. Apoptosis-inducing properties of Viscum album L. Extracts from different host trees, correlate with their content of toxic mistletoe lectins. Anticancer Res. 19 (1999) 23-28
3. Chen, J., Liu, B., Ji, N., Zhou, J., Van Damme, E., Balzarini, J., Chen, F., Bao, J.K., 2008. A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities. Phytomedicine 2008 August 30, doi:10.1016/j.phymed.2008.07.003.
4. de Mejía E.G., and Prisecaru V.I. Lectins as bioactive plant proteins: a potential in cancer treatment. Crit. Rev. Food Sci. Nutr. 45 (2005) 425-445
5. Dhuna V., Kamboj S.S., Kaur A., Saxena A.K., Bhide S.V., Shanmugavel, and Singh J. Characterization of a lectin from Gonatanthus pumilus D. Don having anti-proliferative effect against human cancer cell lines. Protein Pept. Lett. 14 (2007) 71-78
6. Fuke H., Shiraki K., Sugimoto K., Tanaka J., Beppu T., Yoneda K., Yamamoto N., Ito K., Masuya M., and Takei Y. Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells. Biochem. Biophys. Res. Commun. 363 (2007) 738-744
7. Gastman B., Wang K., Han J., Zhu Z.Y., Huang X.J., Wang G.Q., Rabinowich H., and Gorelik E. A novel apoptotic pathway as defined by lectin cellular initiation. Biochem. Biophys. Res. Commun. 316 (2004) 263-271
8. Janssen O., Scheffler A., and Kabelitz D. In vitro effects of mistletoe extracts and mistletoe lectins. Cytotoxicity towards tumor cells due to the induction of programmed cell death (apoptosis). Arzneimittelforschung 43 (1993) 1221-1227
9. Karasaki Y., Tsukamoto S., Mizusaki K., Sugiura T., and Gotoh S. A garlic lectin exerted an antitumor activity and induced apoptosis in human tumor cells. Food Res. Int. 34 (2001) 7-13
10. Kaur M., Singh K., Rup P.J., Kamboj S.S., Saxena A.K., Sharma M., Bhagat M., Sood S.K., and Singh J. A tuber lectin from Arisaema jacquemontii Blume with anti-insect and anti-proliferative properties. J. Biochem. Mol. Biol. 39 (2006) 432-440
11. Kessel D., and Luo Y. Cells in cryptophycin-induced cell-cycle arrest are susceptible to apoptosis. Cancer Lett. 151 (2000) 25-29
12. Kim M.-S., So H.-S., Lee K.-M., Park J.-S., Lee J.-H., Moon S.-K., Ryu D.-G., Chung S.-Y., Jung B.-H., Kim Y.-K., Moon G., and Park R. Activation of caspase cascades in Korean mistletoe (Viscum album var. coloratum) lectin-II-induced apoptosis of human myeloleukemic U937 cells. Gen. Pharmacol. 34 (2000) 349-355
13. Kiss R., Camby I., Duckworth C., Decker R.D., Salmon I., Pasteels J.-L., Danguy A., and Yeaton P. In vitro influence of Phaseolus vulgaris, Griffonia simplicifolia, concanavalin A, wheat germ, and peanut agglutinins on HCT-15, LoVo, and SW837 human colorectal cancer cell growth. Gut 40 (1997) 253-261
14. Koyama Y., Katsuno Y., Miyoshi N., Hayakawa S., Mita T., Muto H., Isemura S., Aoyagi Y., and Isemura M. Apoptosis induction by lectin isolated from the mushroom Boletopsis leucomelas in U937 cells. Biosci. Biotechnol. Biochem. 66 (2002) 784-789
15. Laezza C., Pisanti S., Crescenzi E., and Bifulco M. Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. FEBS Lett. 580 (2006) 6076-6082
16. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277 (1970) 680-685
17. Lin J., Dong H.F., Oppenheim J.J., and Howard O.M. Effects of astragali radix on the growth of different cancer cell lines. World J. Gastroenterol. 9 (2003) 670-673
18. Lin S.Y., Lai W.W., Chou C.C., Kuo H.M., Li T.M., Chung J.G., and Yang J.H. Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375 S2 cells. Melanoma Res. 16 (2006) 509-519
19. Liu W.K., Ho J.C.K., and Ng T.B. Suppression of cell cycle progression by a fungal lectin: activation of cyclin-dependent kinase inhibitors. Biochem. Pharmacol. 61 (2001) 33-37
20. Liu Z., Liu B., Zhang Z.T., Zhou T.T., Bian H.J., Min M.W., Liu Y.H., Chen J., and Bao J.K. A mannose-binding lectin from Sophora flavescens induces apoptosis in HeLa cells. Phytomedicine 15 (2008) 867-875
21. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
22. Luo Y.T., Xu X.C., Liu J.W., Li J., Sun Y.S., Liu Z., Liu J.Z., Van Damme E., Balzarini J., and Bao J.K. A novel mannose-binding tuber lectin from Typhonium divaricatum (L.) Decne (family Araceae) with antiviral activity against HSV-II and anti-proliferative effect on human cancer cell lines. J. Biochem. Mol. Biol. 40 (2007) 358-367
23. Lyu S.Y., Park W.B., Choi K.H., and Kim W.H. Involvement of caspase-3 in apoptosis induced by Viscum album var. coloratum agglutinin in HL-60 cells. Biosci. Biotechnol. Biochem. 65 (2001) 534-541
24. Miyoshi N., Koyama Y., Katsuno Y., Hayakawa S., Mita T., Ohta T., Kaji K., and Isemura M. Apoptosis induction associated with cell cycle dysregulation by rice bran agglutinin. J. Biochem. (Tokyo) 130 (2001) 799-805
25. Reed J.C. Apoptosis-targeted therapies for cancer. Cancer Cell 3 (2003) 17-22
26. Shanker S., and Das R.H. Identification of a cDNA clone encoding for a galactose-binding lectin from peanut (Arachis hypogaea) seedling roots. Biochem. Biophys. Acta 1568 (2001) 105-110
27. Siegle I., Fritz P., McClellan M., Gutzeit S., and Murdter T.E. Combined cytotoxic action of Viscum album agglutinin-1 and anticancer agents against human A549 lung cancer cells. Anticancer Res. 21 (2001) 2687-2691
28. Singh J., Singh J., and Kamboj S.S. A novel mitogenic and antiproliferative lectin from a wild cobra lily, Arisaema flavum. Biochem. Biophys. Res. Commun. 318 (2004) 1057-1065
29. Vermes I., Haanen C., Steffens-Nakken H., and Reutelingsperper C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Annexin V. J. Immunol. Methods 184 (1995) 39-51
30. Vervecken W., Kleff S., Pfüller U., and Büssing A. Induction of apoptosis by mistletoe lectin I and its subunits. No evidence for cytotoxic effects caused by isolated A- and B-chains. Int J. Biochem. Cell Biol. 32 (2000) 317-326
31. Wyllie A.H. Apoptosis: an overview. Br. Med. Bull. 53 (1997) 451-465
32. Yan Q.J., Jiang Z.Q., Yang S.Q., Deng W., and Han L.J. A novel homodimeric lectin from Astragalus mongholicus with antifungal activity. Arch. Biochem. Biophys. 442 (2005) 72-81
33. Yoon T.J., Yoo Y.C., Kang T.B., Shimazaki K.-I., Song S.K., Lee K.H., Kim S.H., Park C.H., Azuma I., and Kim J.B. Lectins isolated from Korean mistletoe (Viscum album coloratum) induce apoptosis in tumor cells. Cancer Lett. 136 (1999) 33-40
34. Zhao C., Sun H., Tong X., and Qi Y. An antitumour lectin from the edible mushroom Agrocybe aegerita. Biochem. J. 374 (2003) 321-327