A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. Extralong Autumn Purple Bean

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 4, 2010, Pages 2221-2229

  Fang, Evandro Fei ^a   Lin, Peng ^a   Wong, Jack Ho ^a   Tsao, Sai Wah ^b   Ng, Tzi Bun ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; LECTIN; MESSENGER RNA; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BEAN; CELL DIVISION; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; ERYTHROCYTE; GENETICS; HEMAGGLUTINATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOLATION AND PURIFICATION; LEGUME; MOLECULAR GENETICS; MOUSE; NASOPHARYNX TUMOR; PHYSIOLOGY; RABBIT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEASON; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; CELL LINE, TUMOR; ENZYME INHIBITORS; ERYTHROCYTES; FABACEAE; HEMAGGLUTINATION; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; LECTINS; MICE; MOLECULAR SEQUENCE DATA; NASOPHARYNGEAL NEOPLASMS; NITRIC OXIDE SYNTHASE TYPE II; PHASEOLUS; RABBITS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEASONS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; ORYCTOLAGUS CUNICULUS; PHASEOLUS VULGARIS; RATTUS; VILLOSA PERPURPUREA;

EID: 77249112249     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf903964u     Document Type: Article

References (45)

1. Sharon, N.; Lis, H. History of lectins: from, hemagglutinins to biological recognition molecules. Glycobiology 2004, 14, 53-62.
2. Sharon, N. Lectins: past, present and future. Biochem. Soc. Trans. 2008, 36, 1457-1460.
3. Lin, P.; Ng, T. B. Preparation and biological properties of a melibiose binding lectin from Bauhinia variegata seeds. J. Agric. Food Chem. 2008, 56, 10481-10486.
4. Sharma, N.; Bajaj, M.; KR, S. Overcoming self-incompatibility through the use of lectins and sugars in petunia and eruca. Ann. Bot. 1985, 55, 139-141.
5. Wong, J. H.; Ng, T. B. Isolation and characterization, of a glucose/ mannose-specific lectin with, stimulatory effect on nitric oxide production by macrophages from the emperor banana. Int. J. Biochem. Cell Biol. 2006, 38, 234-243.
6. Kitagaki, J.; Yang, Y.; Saavedra, J. E.; Colburn, N. H.; Keefer, L. K.; Perantoni, A. O. Nitric oxide prodrug JS-K inhibits ubiquitin El and kills tumor cells retaining wild-type p53. Oncogene 2009, 28, 619-624.
7. Wu, A. M.; Wu, J. H.; Liu, J. H.; Singh, T. Recognition profile of Bauhinia purpurea agglutinin (BPA). Life Sci. 2004, 74, 1763-1779.
8. Wu, A. M.; Wu, J. H.; Yang, Z.; Singh, T.; Goldstein, I. J.; Sharon, N. Differential contributions of recognition factors of two plant lectins-Amaranthus caudatus lectin and Arachis hypogea agglutinin, reacting with Thomsen-Friedenreich disaccharide (Galbetal3GalNAcalphal-Ser/Thr). Biochimie 2008 90, 1769-1780.
9. Alvarez-Manilla, G.; Warren, N. L.; Atwood, J. A.; Dalton, S.; Orlando, R.; Pierce, M. Glycoproteomic analysis of embryonic stem cells: identification of potential glycobiomarkers using lectin, affinity chromatography of glycopeptides J. Proteome Res., in press.
10. Nagler, A.; Morecki, S.; Slavin, S. The use of soybean agglutinin (SBA) for bone marrow (BM) purging and hematopoietic progenitor cell enrichment in clinical bone-marrow transplantation. Mol. Biotechnol. 1999, 11, 181-194.
11. Tanaka, H.; Chiba, H.; Inokoshi, J.; Kuno, A.; Sugai, T.; Takahashi, A.; Ito, Y.; Tsunoda, M.; Suzuki, K.; Takenaka, A.; Sekiguchi, T.; Umeyama, H.; Hirabayashi, J.; Omura, S. Mechanism by which the lectin actinohivin blocks HIV infection of target cells. Proc. Natl. Acad. Sci. U.S.A., in press.
12. Zhang, X.; Blair, M. W.; Wang, S. Genetic diversity of Chinese common, bean (Phaseolus vulgaris L.) landraces assessed with simple sequence repeat markers. Theor. Appl. Genet, 2008, 117, 629-640.
13. Wang, S. M. Food legume crops and their wild relatives in China. In Food crops; Dong, Y. C., Liu, X., Eds.; China Agriculture Press: Beijing, China, 2006; pp 406-479.
14. Sharma, A.; Ng, T. B.; Wong, J. H.; Lin, P. Purification, and characterization of a lectin from Phaseolus vulgaris cv. (Anasazi beans). J. Biomed. Biotechnol, in press.
15. Fang, E. F.; Wong, J. H.; Lin, P.; Ng, T. B. Biochemical and functional properties of a lectin purified from Korean large black soybeans-A cultivar of Glycine Max. Protein Pept. Lett., in press.
16. Wong, J. H.; Wong, C. C.; Ng, T. B. Purification and characterization of a galactose-specific lectin with mitogenic activity from pinto beans. Biochim. Biophys. Acta 2006, 1760, 808-813.
17. Wang, Y.; He, Q. Y.; Tsao, S. W.; Cheung, Y. H.; Wong, A.; Chiu, J. F. Cytokeratin 8 silencing in human nasopharyngeal carcinoma cells leads to cisplatin sensitization. Cancer, Lett. 2008, 265, 188-196.
18. Hwang, J. T.; Ha, J.; Park, I. J.; Lee, S. K.; Baik, H. W.; Kim, Y. M.; Park, O. J. Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway, Cancer Lett. 2007, 247, 115-121.
19. Liu, Y.; Chen, Z.; Ng, T. B.; Zhang, J.; Zhou, M.; Song, F.; Lu, F.; Liu, Y. Bacisubin, an antifungal protein, with ribonuclease and hemagglutinating activities from Bacillus subtilis strain B-916. Peptides 2007, 28, 553-559.
20. Lam, S. K.; Ng, T. B. Isolation and characterization of a French bean hemagglutinin with, antitumor, antifungal, and anti-HIV-1 reverse transcriptase activities and an exceptionally high yield. Phytomedicine, in press.
21. Games, P. D.; Dos Santos, I. S.; Mello, E. O.; Diz, M. S.; Carvalho, A. O.; de Souza-Filho, G. A.; Da Cunha, M.; Vasconcelos, I. M.; Ferreira Bdos, S.; Gomes, V. M. Isolation, characterization and cloning of a cDNA encoding a new antifungal defensin from Phaseolus vulgaris L. seeds, Peptides 2008, 29, 2090-2100.
22. Wong, J. H.; Ng, T. B. Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.). Peptides 2005, 26, 2086-2092.
23. Leung, E. H.; Wong, J. H.; Ng, T. B. Concurrent purification of two defense proteins from French bean seeds: a defensin-like antifungal peptide and a hemagglutinin, J. Pept. Sci. 2008, 14, 349-353.
24. Wong, J. H.; Wong, C. C.; Ng, T. B. Purification and characterization of a galactose-specific lectin with mitogenic activity from, pinto beans. Biochim. Biophys. Acta 2006, 1760, 808-813.
25. Ye, X. Y.; Ng, T. B.; Tsang, P. W.; Wang, J. Isolation of a homodimeric lectin with, antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds. J. Protein Chem. 2001, 20, 367-375.
26. Fabre, C.; Causse, H.; Mourey, L.; Koninkx, J.; Riviere, M.; Hendriks, H.; Puzo, G.; Samama, J. P.; Rouge, P. Characterization and sugar-binding properties of arcelin-1, an insecticidal lectin-like protein isolated from kidney bean (Phaseolus vulgaris L. cv. RAZ-2) seeds. Biochem. J. 1998, 329 (Pt 3), 551-560.
27. Pratt, R. C.; Singh, N. K.; Shade, R. E.; Murdock, L. L.; Bressan, R. A. Isolation and partial characterization of a seed lectin from, tepary bean that delays bruchid beetle development. Plant Physiol. 1990, 93, 1453-1459.
28. Castillo-Villanueva, A.; Caballero-Ortega, H.; Abdullaev-Jafarova, F.; Garfias, Y.; del Carmen Jimenez-Martinez, M.; Bouquelet, S.; Martinez, G.; Mendoza-Hernandez, G.; Zenteno, E. Lectin from Phaseolus acutifolius var. escumite: chemical characterization, sugar specificity, and effect on human T-lymphocytes. J. Agric. Food Chem. 2007, 55, 5781-5787.
29. Pinto, L. S.; Nagano, C. S.; Oliveira, T. M.; Moura, T. R.; Sampaio, A. H.; Debray, H.; Pinto, V. P.; Dellagostin, O. A.; Cavada, B. S. Purification and molecular cloning of a new galactose-specific lectin from Bauhinia variegata seeds. J. Biosci. 2008, 33, 355-363.
30. Suzuki, T.; Amano, Y.; Fujita, M.; Kobayashi, Y.; Dohra, H.; Hirai, H.; Murata, T.; Usui, T.; Morita, T.; Kawagishi, H. Purification, characterization, and cDNA cloning of a lectin from the mushroom Pleurocybella porrigens. Biosci. Biotechnol. Biochem. 2009, 73, 702-709.
31. Sampaio, A. H.; Rogers, D. J.; Barwell, C. J. A galactose-specific lectin from the red marine alga Ptilota filicina. Phytochemistry 1998, 48, 765-769.
32. Borrebaeck, C. A.; Lonnerdal, B.; Etzler, M. E. Metal ion content of Dolichos biflorus lectin and effect of divalent cations on lectin activity. Biochemistry 1981, 20, 4119-4122.
33. Drickamer, K. Two distinct classes of carbohydrate-recognition domains in animal lectins. J. Biol. Chem. 1988, 263, 9557-9560.
34. Morari, D.; Stepurina, T.; Rotari, V. I. Calcium ions make phytohemagglutinin resistant to trypsin, proteolysis. J. Agric. Food. Chem. 2008, 56, 3764-3771.
35. Hayden, E. C. The AIDS fight: looking ahead to 2010. Nature 2008, 454, 812.
36. Ren, J.; Stammers, D. K. Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase. Virus Res. 2008, 134, 157-170.
37. Lam, S. K.; Ng, T. B. First report of a hemagglutinin-induced apoptotic pathway in breast cancer cells. Biosci. Rep., in press.
38. Ramirez, L.; Zabaleta, E. J.; Lamattina, L. Nitric oxide and frataxin: two players contributing to maintain cellular iron homeostasis. Ann. Bot., in press.
39. Lim, K. H.; Ancrile, B. B.; Kashatus, D. F.; Counter, C. M. Tumour maintenance is mediated by eNOS. Nature 2008, 452, 646-649.
40. Chen, C. C.; Chiu, K. T.; Sun, Y. T.; Chen, W. C. Role of the cyclic AMP-protein kinase A pathway in lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages. Involvement of cyclooxygenase-2. J. Biol. Chem. 1999, 274, 31559-31564.
41. Kubota, Y.; Takahashi, S.; Sato, H. Significant contamination of superoxide dismutases and catalases with lipopolysaccharide-like substances. Toxicol. In Vitro 2004, 18, 711-718.
42. Cardoso, L. S.; Araujo, M. I.; Goes, A. M.; Pacifico, L. G.; Oliveira, R. R.; Oliveira, S. C. Polymyxin. B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis. Microb. Cell Fact, 2007, 6, 1-6.
43. Cruz, M. T.; Duarte, C. B.; Goncalo, M.; Carvalho, A. P.; Lopes, M. C. LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42. Nitric Oxide 2001, 5, 53-61.
44. Chen, J.; Liu, B.; Ji, N.; Zhou, J.; Bian, H. J.; Li, C. Y.; Chen, F.; Bao, J. K. A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities, Phytomedicine 2009, 16, 352-360.
45. Wong, J. H.; Ng, T. B. A homotetrameric agglutinin with antiproliferative and mitogenic activities from haricot beans. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2005, 828, 130-135.