RIP140 is associated with subclinical inflammation in type 2 diabetic patients

Experimental and Clinical Endocrinology and Diabetes

Volumn 121, Issue 1, 2013, Pages 37-42

  Xue, J ^a   Zhao, H ^b   Shang, G ^c   Zou, R ^a   Dai, Z ^a   Zhou, D ^a   Huang, Q ^a   Xu, Y ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b Xinjiang Uygur Autonomous Region People's Hospital   (China)

^c WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

diabetes; inflammatory cytokines; RIP140

Indexed keywords

FATTY ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RECEPTOR INTERACTING PROTEIN 140; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DIABETIC PATIENT; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY ACID BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LIPID METABOLISM; LIPIDS; MALE; MIDDLE AGED; NUCLEAR PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84872615525     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0032-1323683     Document Type: Article

References (36)

1. Donath M. Y., Shoelson S. E. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol: 2011; 11 98 107
2. Roberts D. L., Dive C., Renehan A. G. Biological mechanisms linking obesity and cancer risk: new perspectives. Annu Rev Med: 2010; 61 301 316
3. Tajiri Y., Mimura K., Umeda F. High-sensitivity C-reactive protein in Japanese patients with type 2 diabetes. Obes Res: 2005; 13 1810 1816
4. Wellen K. E., Hotamisligil G. S. Inflammation, stress, and diabetes. J Clin Invest: 2005; 115 1111 1119 (Pubitemid 40629025)
5. Cai D., Yuan M., Frantz D. F. et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med: 2005; 11 183 190 (Pubitemid 40321354)
6. Duncan B. B., Schmidt M. I., Pankow J. S. et al. Low-Grade Systemic Inflammation and the development of type 2 Diabetes. Diabetes: 2003; 52 1799 1805
7. Nguyen M. T., Favelyukis S., Nguyen A. K. et al. A Subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem: 2007; 282 35279 35292 (Pubitemid 350232441)
8. Schulman I. G. Nuclear receptors as drug targets for metabolic disease. Adv Drug Deli Rev: 2010; 62 1307 1315
9. Handschin C., Spiegelman B. M. The role of exercise and PGC-1 alpha in inflammation and chronic disease. Nature: 2008; 454 463 469
10. Mootha V. K., Lindgren C. M., Eriksson K. F. et al. PGC-1 alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet: 2003; 34 267 273 (Pubitemid 36792858)
11. Handschin C. C., Choi C. S., Chin S. et al. Abnormal glucose homeostasis in skeletal muscle-specific PGC-1 alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J Clin Invest: 2007; 117 3463 3474 (Pubitemid 350097002)
12. Rosell M., Jones M. C., Parker M. G. Role of nuclear receptor corepressor RIP140 in metabolic syndrome. Biochim Biophys Acta: 2011; 1812 919 928
13. Cavailles V., Dauvois S., Danielian P. S. et al. Interaction of proteins with transcriptionally active estrogen receptors. Proc Natl Acad Sci USA: 1994; 91 10009 10013 (Pubitemid 24311938)
14. Leonardsson G., Steel J. H., Christian M. et al. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci USA: 2004; 101 8437 8442 (Pubitemid 38736593)
15. Seth A., Steel J. H., Nichol D. et al. The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. Cell Metab: 2007; 6 236 245 (Pubitemid 47324141)
16. Herzog B., Hallberg M., Seth A. et al. The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor. Mol Endocrinol: 2007; 21 2687 2697 (Pubitemid 350035151)
17. Zschiedrich I., Hardeland U., Krones-Herzig A. et al. Coactivator function of RIP140 for NF-kappa B/rela-dependent cytokine gene expression. Blood: 2008; 112 264 276
18. Ho P. C., Tsui Y. C., Feng X. D. et al. NF-kappa B-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance. Nat Immunol: 2012; 13 379 386
19. Ho P. C., Chang K. C., Chuang Y. S. et al. Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production. FASEB J: 2011; 25 1758 1766
20. Catalan V., Gómez-Ambrosi J., Lizanzu A. et al. RIP140 gene and protein expression levels are downregulated in visceral adipose tissue in human morbid obesity. Obes Surg: 2009; 19 771 776
21. Patti M. E., Butte A. J., Crunkhorn S. et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA: 2003; 100 8466 8471 (Pubitemid 36842568)
22. Hallberg M., Morganstein D. L., Kiskinis E. et al. A functional interaction between RIP140 and PGC-1α regulates the expression of the lipid droplet protein CIDEA. Mol Cell Biol: 2008; 28 6785 6795
23. Ghanim H., Aljada A., Hofmeyer D. et al. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation: 2004; 110 1564 1571 (Pubitemid 39297977)
24. Sheu W. H., Chang T. M., Lee W. J. et al. Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Obesity: 2008; 16 1033 1038 (Pubitemid 351620479)
25. Weisberg S. P., McCann D., Desai M. et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest: 2003; 112 1796 1808 (Pubitemid 38063703)
26. Cousin S. P., Hüql S. R., Wrede C. E. et al. Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic β-cell line INS-1. Endocrinology: 2001; 142 229 240 (Pubitemid 32183685)
27. Livak K. J., Schmittgen T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods: 2001; 25 402 408 (Pubitemid 34164012)
28. Mejhert N., Laurencikiene J., Pettersson A. T. et al. Role of Receptor-Interacting Protein 140 in human fat cells. BMC Endocr Disord: 2010; 10 1 8
29. Powelka A. M., Seth A., Virbasius J. V. et al. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest: 2006; 116 125 136 (Pubitemid 43121797)
30. Baker R. G., Hayden M. S., Ghosh S. NF-kappaB, inflammation, and metabolic disease. Cell Metab: 2011; 13 11 22
31. Olefsky J. M., Glass C. K. Macrophages, inflammation, and insulin Resistance. Annu Rev Physiol: 2010; 72 219 246
32. Mirza S., Hossain M., Mathews C. et al. Type 2-diabetes is associated with elevated levels of TNF-alpha, IL-6 and adiponectin and low levels of leptin in a population of Mexican Americans: A cross-sectional study. Cytokine: 2012; 57 136 142
33. Ghanim H., Aljada A., Daoud N. et al. Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects. Diabetologia: 2007; 50 278 285
34. Kim F., Pham M., Luttrell I. et al. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res: 2007; 100 1589 1596 (Pubitemid 46897262)
35. Huang Y., Liu J., Xu Y. et al. Reduction of insulin resistance in HepG2 cells by knockdown of LITAF expression in human THP-1 macrophages. J Huazhong Univ Sci Technolog Med Sci: 2012; 32 53 58
36. Tripathy D., Mohanty P., Dhindsa S. et al. Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes: 2003; 52 2882 2887 (Pubitemid 37466856)