-
1
-
-
0032802780
-
Spinocerebellar ataxia type 2 in southern Italy: A clinical and molecular study of 30 families
-
Filla A, De Michele G, Santoro L, Calabrese O, Castaldo I, Giuffrida S, et al. Spinocerebellar ataxia type 2 in southern Italy: a clinical and molecular study of 30 families. J Neurol. 1999;246 (6):467-71.
-
(1999)
J Neurol.
, vol.246
, Issue.6
, pp. 467-471
-
-
Filla, A.1
De Michele, G.2
Santoro, L.3
Calabrese, O.4
Castaldo, I.5
Giuffrida, S.6
-
2
-
-
11144356369
-
Autosomal dominant cerebellar ataxias: Clinical features, genetics, and pathogenesis
-
Schols L, Bauer P, Schmidt T, Schulte T, Riess O. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. Lancet Neurol. 2004;3(5):291-304.
-
(2004)
Lancet Neurol.
, vol.3
, Issue.5
, pp. 291-304
-
-
Schols, L.1
Bauer, P.2
Schmidt, T.3
Schulte, T.4
Riess, O.5
-
4
-
-
77955480316
-
Cellular and molecular pathways triggering neurodegeneration in the spinocerebellar ataxias
-
Matilla-Duenas A, Sanchez I, Corral-Juan M, Davalos A, Alvarez R, Latorre P. Cellular and Molecular Pathways Triggering Neurodegeneration in the Spinocerebellar Ataxias. Cerebellum. 2010; 9(2):148-66.
-
(2010)
Cerebellum
, vol.9
, Issue.2
, pp. 148-166
-
-
Matilla-Duenas, A.1
Sanchez, I.2
Corral-Juan, M.3
Davalos, A.4
Alvarez, R.5
Latorre, P.6
-
5
-
-
70349105130
-
The spinocerebellar ataxias
-
Paulson HL. The spinocerebellar ataxias. J Neuroophthalmol. 2009;29(3):227-37.
-
(2009)
J Neuroophthalmol
, vol.29
, Issue.3
, pp. 227-237
-
-
Paulson, H.L.1
-
6
-
-
68649121647
-
Emerging pathogenic pathways in the spinocerebellar ataxias
-
Carlson KM, Andresen JM, Orr HT. Emerging pathogenic pathways in the spinocerebellar ataxias. Curr Opin Genet Dev. 2009;19(3):247-53.
-
(2009)
Curr Opin Genet Dev
, vol.19
, Issue.3
, pp. 247-253
-
-
Carlson, K.M.1
Andresen, J.M.2
Orr, H.T.3
-
7
-
-
84930538107
-
Therapeutic prospects for spinocerebellar ataxia type 2 and 3
-
Bezprozvanny I, Klockgether T. Therapeutic prospects for spinocerebellar ataxia type 2 and 3. Drugs of the Future. 2010;34(12):991-9.
-
(2010)
Drugs of the Future
, vol.34
, Issue.12
, pp. 991-999
-
-
Bezprozvanny, I.1
Klockgether, T.2
-
8
-
-
0037294184
-
Chronic thalamic stimulation in a patient with spinocerebellar ataxia type 2
-
Pirker W, Back C, Gerschlager W, Laccone F, Alesch F. Chronic thalamic stimulation in a patient with spinocerebellar ataxia type 2. Mov Disord. 2003;18(2):222-5.
-
(2003)
Mov Disord.
, vol.18
, Issue.2
, pp. 222-225
-
-
Pirker, W.1
Back, C.2
Gerschlager, W.3
Laccone, F.4
Alesch, F.5
-
9
-
-
0033995175
-
Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1
-
Lin X, Antalffy B, Kang D, Orr HT, Zoghbi HY. Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1. Nat Neurosci. 2000;3(2):157-63.
-
(2000)
Nat Neurosci.
, vol.3
, Issue.2
, pp. 157-163
-
-
Lin, X.1
Antalffy, B.2
Kang, D.3
Orr, H.T.4
Zoghbi, H.Y.5
-
10
-
-
0034653926
-
Relationship between ataxin-1 nuclear inclusions and Purkinje cell specific proteins in SCA-1 transgenic mice
-
Vig PJ, Subramony SH, Qin Z, McDaniel DO, Fratkin JD. Relationship between ataxin-1 nuclear inclusions and Purkinje cell specific proteins in SCA-1 transgenic mice. J Neurol Sci. 2000;174(2):100-10.
-
(2000)
J Neurol Sci.
, vol.174
, Issue.2
, pp. 100-110
-
-
Vig, P.J.1
Subramony, S.H.2
Qin, Z.3
McDaniel, D.O.4
Fratkin, J.D.5
-
11
-
-
33750815242
-
RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice
-
Serra HG, Duvick L, Zu T, Carlson K, Stevens S, Jorgensen N, et al. RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice. Cell. 2006;127 (4):697-708.
-
(2006)
Cell.
, vol.127
, Issue.4
, pp. 697-708
-
-
Serra, H.G.1
Duvick, L.2
Zu, T.3
Carlson, K.4
Stevens, S.5
Jorgensen, N.6
-
13
-
-
58149375272
-
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
-
Chen X, Tang T-S, Tu H, Nelson O, Pook MA, Hammer RE, et al. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3. J Neurosci. 2008;28:12713-24.
-
(2008)
J Neurosci.
, vol.28
, pp. 12713-12724
-
-
Chen, X.1
Tang, T.-S.2
Tu, H.3
Nelson, O.4
Pook, M.A.5
Hammer, R.E.6
-
14
-
-
54749151920
-
Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families
-
Hara K, Shiga A, Nozaki H, Mitsui J, Takahashi Y, Ishiguro H, et al. Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families. Neurology. 2008;71(8):547-51.
-
(2008)
Neurology.
, vol.71
, Issue.8
, pp. 547-551
-
-
Hara, K.1
Shiga, A.2
Nozaki, H.3
Mitsui, J.4
Takahashi, Y.5
Ishiguro, H.6
-
15
-
-
38349116798
-
Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16
-
Iwaki A, Kawano Y, Miura S, Shibata H, Matsuse D, Li W, et al. Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16. J Med Genet. 2008;45(1):32-5.
-
(2008)
J Med Genet.
, vol.45
, Issue.1
, pp. 32-35
-
-
Iwaki, A.1
Kawano, Y.2
Miura, S.3
Shibata, H.4
Matsuse, D.5
Li, W.6
-
16
-
-
50149093030
-
Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels
-
Watase K, Barrett CF, Miyazaki T, Ishiguro T, Ishikawa K, Hu Y, et al. Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels. Proc Natl Acad Sci USA. 2008;105(33):11987-92.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.33
, pp. 11987-11992
-
-
Watase, K.1
Barrett, C.F.2
Miyazaki, T.3
Ishiguro, T.4
Ishikawa, K.5
Hu, Y.6
-
17
-
-
67651183756
-
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2
-
Liu J, Tang TS, Tu H, Nelson O, Herndon E, Huynh DP, et al. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. J Neurosci. 2009;29(29):9148-62.
-
(2009)
J Neurosci.
, vol.29
, Issue.29
, pp. 9148-9162
-
-
Liu, J.1
Tang, T.S.2
Tu, H.3
Nelson, O.4
Herndon, E.5
Huynh, D.P.6
-
18
-
-
77952889769
-
Human ataxias: A genetic dissection of inositol triphosphate receptor (ITPR1-dependent signaling
-
Mar 10, PMID: 20226542
-
Schorge S, van de Leemput J, Singleton A, Houlden H, Hardy J. Human ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling. Trends Neurosci. 2010 Mar 10. PMID: 20226542.
-
(2010)
Trends Neurosci
-
-
Schorge, S.1
Van De Leemput, J.2
Singleton, A.3
Houlden, H.4
Hardy, J.5
-
19
-
-
52049127039
-
From synapse to nucleus: Calciumdependent gene transcription in the control of synapse development and function
-
Greer PL, Greenberg ME. From synapse to nucleus: calciumdependent gene transcription in the control of synapse development and function. Neuron. 2008;59(6):846-60.
-
(2008)
Neuron.
, vol.59
, Issue.6
, pp. 846-860
-
-
Greer, P.L.1
Greenberg, M.E.2
-
20
-
-
52049106127
-
Multiple roles of calcium ions in the regulation of neurotransmitter release
-
Neher E, Sakaba T. Multiple roles of calcium ions in the regulation of neurotransmitter release. Neuron. 2008;59(6):861-72.
-
(2008)
Neuron.
, vol.59
, Issue.6
, pp. 861-872
-
-
Neher, E.1
Sakaba, T.2
-
21
-
-
61849142791
-
Calcium signaling and neurodegenerative diseases
-
Bezprozvanny I. Calcium signaling and neurodegenerative diseases. Trends Mol Med. 2009;15(3):89-100.
-
(2009)
Trends Mol Med.
, vol.15
, Issue.3
, pp. 89-100
-
-
Bezprozvanny, I.1
-
22
-
-
1642360155
-
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia
-
Shakkottai VG, Chou CH, Oddo S, Sailer CA, Knaus HG, Gutman GA, et al. Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. J Clin Invest. 2004;113(4):582-90.
-
(2004)
J Clin Invest.
, vol.113
, Issue.4
, pp. 582-590
-
-
Shakkottai, V.G.1
Chou, C.H.2
Oddo, S.3
Sailer, C.A.4
Knaus, H.G.5
Gutman, G.A.6
-
24
-
-
0030292488
-
Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2
-
Pulst SM, Nechiporuk A, Nechiporuk T, Gispert S, Chen XN, Lopes-Cendes I, et al. Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2. Nat Genet. 1996;14(3):269-76.
-
(1996)
Nat Genet.
, vol.14
, Issue.3
, pp. 269-276
-
-
Pulst, S.M.1
Nechiporuk, A.2
Nechiporuk, T.3
Gispert, S.4
Chen, X.N.5
Lopes-Cendes, I.6
-
25
-
-
0030294345
-
Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats
-
Imbert G, Saudou F, Yvert G, Devys D, Trottier Y, Garnier JM, et al. Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. Nat Genet. 1996;14(3):285-91.
-
(1996)
Nat Genet.
, vol.14
, Issue.3
, pp. 285-291
-
-
Imbert, G.1
Saudou, F.2
Yvert, G.3
Devys, D.4
Trottier, Y.5
Garnier, J.M.6
-
26
-
-
0030292368
-
Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique DIRECT
-
Sanpei K, Takano H, Igarashi S, Sato T, Oyake M, Sasaki H, et al. Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet. 1996;14(3):277-84.
-
(1996)
Nat Genet.
, vol.14
, Issue.3
, pp. 277-284
-
-
Sanpei, K.1
Takano, H.2
Igarashi, S.3
Sato, T.4
Oyake, M.5
Sasaki, H.6
-
27
-
-
0033811788
-
Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human
-
Huynh DP, Figueroa K, Hoang N, Pulst SM. Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human. Nat Genet. 2000;26 (1):44-50.
-
(2000)
Nat Genet.
, vol.26
, Issue.1
, pp. 44-50
-
-
Huynh, D.P.1
Figueroa, K.2
Hoang, N.3
Pulst, S.M.4
-
28
-
-
0034457113
-
The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans
-
Kiehl TR, Shibata H, Pulst SM. The ortholog of human ataxin-2 is essential for early embryonic patterning in C. elegans. J Mol Neurosci. 2000;15(3):231-41.
-
(2000)
J Mol Neurosci.
, vol.15
, Issue.3
, pp. 231-241
-
-
Kiehl, T.R.1
Shibata, H.2
Pulst, S.M.3
-
29
-
-
0036962392
-
A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation
-
Satterfield TF, Jackson SM, Pallanck LJ. A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation. Genetics. 2002;162 (4):1687-702.
-
(2002)
Genetics.
, vol.162
, Issue.4
, pp. 1687-702
-
-
Satterfield, T.F.1
Jackson, S.M.2
Pallanck, L.J.3
-
30
-
-
28144444458
-
Generation and characterization of Sca2 (ataxin-2) knockout mice
-
Kiehl TR, Nechiporuk A, Figueroa KP, Keating MT, Huynh DP, Pulst SM. Generation and characterization of Sca2 (ataxin-2) knockout mice. Biochem Biophys Res Commun. 2006;339(1):17-24.
-
(2006)
Biochem Biophys Res Commun.
, vol.339
, Issue.1
, pp. 17-24
-
-
Kiehl, T.R.1
Nechiporuk, A.2
Figueroa, K.P.3
Keating, M.T.4
Huynh, D.P.5
Pulst, S.M.6
-
31
-
-
26044439653
-
Spinocerebellar ataxia type 2: PolyQ repeat variation in the CACNA1A calcium channel modifies age of onset
-
Pulst SM, Santos N, Wang D, Yang H, Huynh D, Velazquez L, et al. Spinocerebellar ataxia type 2: polyQ repeat variation in the CACNA1A calcium channel modifies age of onset. Brain. 2005;128(Pt 10):2297-303.
-
(2005)
Brain.
, vol.128
, Issue.PART 10
, pp. 2297-2303
-
-
Pulst, S.M.1
Santos, N.2
Wang, D.3
Yang, H.4
Huynh, D.5
Velazquez, L.6
-
32
-
-
0027829495
-
Widespread expression of inositol 1,4, 5- trisphosphate receptor type 1 gene (Insp3r1) in the mouse central nervous system
-
Furuichi T, Simon-Chazottes D, Fujino I, Yamada N, Hasegawa M, Miyawaki A, et al. Widespread expression of inositol 1, 4, 5- trisphosphate receptor type 1 gene (Insp3r1) in the mouse central nervous system. Recept Channels. 1993;1(1):11-24.
-
(1993)
Recept Channels.
, vol.1
, Issue.1
, pp. 11-24
-
-
Furuichi, T.1
Simon-Chazottes, D.2
Fujino, I.3
Yamada, N.4
Hasegawa, M.5
Miyawaki, A.6
-
33
-
-
0033526114
-
Differential cellular expression of isoforms of inositol 1,4, 5-triphosphate receptors in neurons and glia in brain
-
Sharp AH, Nucifora Jr FC, Blondel O, Sheppard CA, Zhang C, Snyder SH, et al. Differential cellular expression of isoforms of inositol 1, 4, 5-triphosphate receptors in neurons and glia in brain. J Comp Neurol. 1999;406(2):207-20.
-
(1999)
J Comp Neurol.
, vol.406
, Issue.2
, pp. 207-220
-
-
Sharp, A.H.1
Nucifora Jr., F.C.2
Blondel, O.3
Sheppard, C.A.4
Zhang, C.5
Snyder, S.H.6
-
34
-
-
57449116963
-
Ataxin-2 associates with rough endoplasmic reticulum
-
van de Loo S, Eich F, Nonis D, Auburger G, Nowock J. Ataxin-2 associates with rough endoplasmic reticulum. Exp Neurol. 2009;215(1):110-8.
-
(2009)
Exp Neurol.
, vol.215
, Issue.1
, pp. 110-118
-
-
Van De Loo, S.1
Eich, F.2
Nonis, D.3
Auburger, G.4
Nowock, J.5
-
35
-
-
0032942714
-
Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: Phylogenetic and developmental patterns
-
Hof PR, Glezer II, Conde F, Flagg RA, Rubin MB, Nimchinsky EA, et al. Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: phylogenetic and developmental patterns. J Chem Neuroanat. 1999;16(2):77-116.
-
(1999)
J Chem Neuroanat.
, vol.16
, Issue.2
, pp. 77-116
-
-
Hof, P.R.1
Glezer, I.I.2
Conde, F.3
Flagg, R.A.4
Rubin, M.B.5
Nimchinsky, E.A.6
-
36
-
-
0031019589
-
Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene
-
Airaksinen MS, Eilers J, Garaschuk O, Thoenen H, Konnerth A, Meyer M. Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci USA. 1997;94(4):1488-93.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.4
, pp. 1488-1493
-
-
Airaksinen, M.S.1
Eilers, J.2
Garaschuk, O.3
Thoenen, H.4
Konnerth, A.5
Meyer, M.6
-
37
-
-
33847356372
-
Differences in locomotor behavior revealed in mice deficient for the calcium-binding proteins parvalbumin, calbindin D-28k or both
-
Farre-Castany MA, Schwaller B, Gregory P, Barski J, Mariethoz C, Eriksson JL, et al. Differences in locomotor behavior revealed in mice deficient for the calcium-binding proteins parvalbumin, calbindin D-28k or both. Behav Brain Res. 2007;178(2):250-61.
-
(2007)
Behav Brain Res.
, vol.178
, Issue.2
, pp. 250-261
-
-
Farre-Castany, M.A.1
Schwaller, B.2
Gregory, P.3
Barski, J.4
Mariethoz, C.5
Eriksson, J.L.6
-
38
-
-
0034111417
-
Alterations in Purkinje cell spines of calbindin D-28 k and parvalbumin knock-out mice
-
Vecellio M, Schwaller B, Meyer M, Hunziker W, Celio MR. Alterations in Purkinje cell spines of calbindin D-28 k and parvalbumin knock-out mice. Eur J Neurosci. 2000;12(3):945-54.
-
(2000)
Eur J Neurosci.
, vol.12
, Issue.3
, pp. 945-954
-
-
Vecellio, M.1
Schwaller, B.2
Meyer, M.3
Hunziker, W.4
Celio, M.R.5
-
39
-
-
44749089373
-
High- and lowcalcium- dependent mechanisms of mitochondrial calcium signalling
-
Spat A, Szanda G, Csordas G, Hajnoczky G. High- and lowcalcium- dependent mechanisms of mitochondrial calcium signalling. Cell Calcium. 2008;44(1):51-63.
-
(2008)
Cell Calcium.
, vol.44
, Issue.1
, pp. 51-63
-
-
Spat, A.1
Szanda, G.2
Csordas, G.3
Hajnoczky, G.4
-
41
-
-
9644310547
-
Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures
-
Campisi A, Caccamo D, Li Volti G, Curro M, Parisi G, Avola R, et al. Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures. FEBS Lett. 2004;578(1-2):80-4.
-
(2004)
FEBS Lett.
, vol.578
, Issue.1-2
, pp. 80-84
-
-
Campisi, A.1
Caccamo, D.2
Li Volti, G.3
Curro, M.4
Parisi, G.5
Avola, R.6
-
42
-
-
53749096967
-
Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration
-
Vosler PS, Brennan CS, Chen J. Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol Neurobiol. 2008;38(1):78-100.
-
(2008)
Mol Neurobiol.
, vol.38
, Issue.1
, pp. 78-100
-
-
Vosler, P.S.1
Brennan, C.S.2
Chen, J.3
-
43
-
-
71549170836
-
Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications
-
Bolanos JP, Moro MA, Lizasoain I, Almeida A. Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: therapeutic implications. Adv Drug Deliv Rev. 2009;61 (14):1299-315.
-
(2009)
Adv Drug Deliv Rev.
, vol.61
, Issue.14
, pp. 1299-1315
-
-
Bolanos, J.P.1
Moro, M.A.2
Lizasoain, I.3
Almeida, A.4
-
44
-
-
0033680563
-
Coincidence detection in single dendritic spines mediated by calcium release
-
Wang SS, Denk W, Hausser M. Coincidence detection in single dendritic spines mediated by calcium release. Nat Neurosci. 2000;3(12):1266-73.
-
(2000)
Nat Neurosci.
, vol.3
, Issue.12
, pp. 1266-1273
-
-
Wang, S.S.1
Denk, W.2
Hausser, M.3
-
45
-
-
0033636896
-
Local calcium release in dendritic spines required for long-term synaptic depression
-
Miyata M, Finch EA, Khiroug L, Hashimoto K, Hayasaka S, Oda SI, et al. Local calcium release in dendritic spines required for long-term synaptic depression. Neuron. 2000;28(1):233-44.
-
(2000)
Neuron.
, vol.28
, Issue.1
, pp. 233-244
-
-
Miyata, M.1
Finch, E.A.2
Khiroug, L.3
Hashimoto, K.4
Hayasaka, S.5
Oda, S.I.6
-
46
-
-
0032585614
-
Local calcium signalling by inositol-1,4, 5-trisphosphate in Purkinje cell dendrites
-
Finch EA, Augustine GJ. Local calcium signalling by inositol-1, 4, 5-trisphosphate in Purkinje cell dendrites. Nature. 1998;396 (6713):753-6.
-
(1998)
Nature.
, vol.396
, Issue.6713
, pp. 753-756
-
-
Finch, E.A.1
Augustine, G.J.2
-
47
-
-
8844227570
-
Bidirectional parallel fiber plasticity in the cerebellum under climbing fiber control
-
Coesmans M, Weber JT, De Zeeuw CI, Hansel C. Bidirectional parallel fiber plasticity in the cerebellum under climbing fiber control. Neuron. 2004;44(4):691-700.
-
(2004)
Neuron.
, vol.44
, Issue.4
, pp. 691-700
-
-
Coesmans, M.1
Weber, J.T.2
De Zeeuw, C.I.3
Hansel, C.4
-
48
-
-
33749595411
-
Synaptic memories upside down: Bidirectional plasticity at cerebellar parallel fiber-Purkinje cell synapses
-
Jorntell H, Hansel C. Synaptic memories upside down: bidirectional plasticity at cerebellar parallel fiber-Purkinje cell synapses. Neuron. 2006;52(2):227-38.
-
(2006)
Neuron.
, vol.52
, Issue.2
, pp. 227-238
-
-
Jorntell, H.1
Hansel, C.2
-
49
-
-
43749093451
-
Type-1 metabotropic glutamate receptor in cerebellar Purkinje cells: A key molecule responsible for long-term depression, endocannabinoid signalling and synapse elimination
-
Kano M, Hashimoto K, Tabata T. Type-1 metabotropic glutamate receptor in cerebellar Purkinje cells: a key molecule responsible for long-term depression, endocannabinoid signalling and synapse elimination. Philos Trans R Soc Lond B Biol Sci. 2008;363 (1500):2173-86.
-
(2008)
Philos Trans R Soc Lond B Biol Sci.
, vol.363
, Issue.1500
, pp. 2173-2186
-
-
Kano, M.1
Hashimoto, K.2
Tabata, T.3
-
50
-
-
0035974794
-
Neuronal glutamate transporters control activation of postsynaptic metabotropic glutamate receptors and influence cerebellar long-term depression
-
Brasnjo G, Otis TS. Neuronal glutamate transporters control activation of postsynaptic metabotropic glutamate receptors and influence cerebellar long-term depression. Neuron. 2001;31 (4):607-16.
-
(2001)
Neuron.
, vol.31
, Issue.4
, pp. 607-616
-
-
Brasnjo, G.1
Otis, T.S.2
-
51
-
-
28044433387
-
Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores
-
Kimura T, Sugimori M, Llinas RR. Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores. Proc Natl Acad Sci USA. 2005;102(47):17160-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.47
, pp. 17160-17165
-
-
Kimura, T.1
Sugimori, M.2
Llinas, R.R.3
-
52
-
-
28044462893
-
Normal motor learning during pharmacological prevention of Purkinje cell long-term depression
-
Welsh JP, Yamaguchi H, Zeng XH, Kojo M, Nakada Y, Takagi A, et al. Normal motor learning during pharmacological prevention of Purkinje cell long-term depression. Proc Natl Acad Sci USA. 2005;102(47):17166-71.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.47
, pp. 17166-17171
-
-
Welsh, J.P.1
Yamaguchi, H.2
Zeng, X.H.3
Kojo, M.4
Nakada, Y.5
Takagi, A.6
-
53
-
-
0032528155
-
Type 1 inositol 1,4, 5- trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons
-
Inoue T, Kato K, Kohda K, Mikoshiba K. Type 1 inositol 1, 4, 5- trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons. J Neurosci. 1998;18 (14):5366-73.
-
(1998)
J Neurosci.
, vol.18
, Issue.14
, pp. 5366-5373
-
-
Inoue, T.1
Kato, K.2
Kohda, K.3
Mikoshiba, K.4
-
54
-
-
0034937247
-
Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons
-
Barenberg P, Strahlendorf H, Strahlendorf J. Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons. Neurosci Res. 2001;40(3):245-54.
-
(2001)
Neurosci Res.
, vol.40
, Issue.3
, pp. 245-254
-
-
Barenberg, P.1
Strahlendorf, H.2
Strahlendorf, J.3
-
55
-
-
10744230059
-
AMPA-induced dark cell degeneration of cerebellar Purkinje neurons involves activation of caspases and apparent mitochondrial dysfunction
-
Strahlendorf J, Box C, Attridge J, Diertien J, Finckbone V, Henne WM, et al. AMPA-induced dark cell degeneration of cerebellar Purkinje neurons involves activation of caspases and apparent mitochondrial dysfunction. Brain Res. 2003;994(2):146-59.
-
(2003)
Brain Res.
, vol.994
, Issue.2
, pp. 146-159
-
-
Strahlendorf, J.1
Box, C.2
Attridge, J.3
Diertien, J.4
Finckbone, V.5
Henne, W.M.6
-
56
-
-
67651154308
-
Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration
-
Maltecca F, Magnoni R, Cerri F, Cox GA, Quattrini A, Casari G. Haploinsufficiency of AFG3L2, the gene responsible for spinocerebellar ataxia type 28, causes mitochondria-mediated Purkinje cell dark degeneration. J Neurosci. 2009;29(29):9244-54.
-
(2009)
J Neurosci.
, vol.29
, Issue.29
, pp. 9244-9254
-
-
Maltecca, F.1
Magnoni, R.2
Cerri, F.3
Cox, G.A.4
Quattrini, A.5
Casari, G.6
-
57
-
-
33749010065
-
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
-
Custer SK, Garden GA, Gill N, Rueb U, Libby RT, Schultz C, et al. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nat Neurosci. 2006;9(10):1302-11.
-
(2006)
Nat Neurosci.
, vol.9
, Issue.10
, pp. 1302-1311
-
-
Custer, S.K.1
Garden, G.A.2
Gill, N.3
Rueb, U.4
Libby, R.T.5
Schultz, C.6
-
58
-
-
65549134765
-
Pathogenic mechanisms of a polyglutaminemediated neurodegenerative disease, spinocerebellar ataxia type 1
-
Zoghbi HY, Orr HT. Pathogenic mechanisms of a polyglutaminemediated neurodegenerative disease, spinocerebellar ataxia type 1. J Biol Chem. 2009;284(12):7425-9.
-
(2009)
J Biol Chem.
, vol.284
, Issue.12
, pp. 7425-7429
-
-
Zoghbi, H.Y.1
Orr, H.T.2
-
59
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement IA, Skinner PJ, Kaytor MD, Yi H, Hersch SM, Clark HB, et al. Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell. 1998;95(1):41-53.
-
(1998)
Cell.
, vol.95
, Issue.1
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
Yi, H.4
Hersch, S.M.5
Clark, H.B.6
-
60
-
-
34548452053
-
Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1
-
Goold R, Hubank M, Hunt A, Holton J, Menon RP, Revesz T, et al. Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1. Hum Mol Genet. 2007;16(17):2122-34.
-
(2007)
Hum Mol Genet.
, vol.16
, Issue.17
, pp. 2122-2134
-
-
Goold, R.1
Hubank, M.2
Hunt, A.3
Holton, J.4
Menon, R.P.5
Revesz, T.6
-
61
-
-
19544374135
-
Gene profiling links SCA1 pathophysiology to glutamate signaling in Purkinje cells of transgenic mice
-
Serra HG, Byam CE, Lande JD, Tousey SK, Zoghbi HY, Orr HT. Gene profiling links SCA1 pathophysiology to glutamate signaling in Purkinje cells of transgenic mice. Hum Mol Genet. 2004;13 (20):2535-43.
-
(2004)
Hum Mol Genet.
, vol.13
, Issue.20
, pp. 2535-2543
-
-
Serra, H.G.1
Byam, C.E.2
Lande, J.D.3
Tousey, S.K.4
Zoghbi, H.Y.5
Orr, H.T.6
-
62
-
-
0035070146
-
Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice
-
Inoue T, Lin X, Kohlmeier KA, Orr HT, Zoghbi HY, Ross WN. Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice. J Neurophysiol. 2001;85(4):1750-60.
-
(2001)
J Neurophysiol.
, vol.85
, Issue.4
, pp. 1750-1760
-
-
Inoue, T.1
Lin, X.2
Kohlmeier, K.A.3
Orr, H.T.4
Zoghbi, H.Y.5
Ross, W.N.6
-
64
-
-
31744441984
-
Spectrin mutations cause spinocerebellar ataxia type 5
-
Ikeda Y, Dick KA, Weatherspoon MR, Gincel D, Armbrust KR, Dalton JC, et al. Spectrin mutations cause spinocerebellar ataxia type 5. Nat Genet. 2006;38(2):184-90.
-
(2006)
Nat Genet.
, vol.38
, Issue.2
, pp. 184-190
-
-
Ikeda, Y.1
Dick, K.A.2
Weatherspoon, M.R.3
Gincel, D.4
Armbrust, K.R.5
Dalton, J.C.6
-
65
-
-
0024273138
-
Electron microscopic localization of type i protein kinase C in rat Purkinje cells
-
Kose A, Saito N, Ito H, Kikkawa U, Nishizuka Y, Tanaka C. Electron microscopic localization of type I protein kinase C in rat Purkinje cells. J Neurosci. 1988;8(11):4262-8.
-
(1988)
J Neurosci.
, vol.8
, Issue.11
, pp. 4262-4268
-
-
Kose, A.1
Saito, N.2
Ito, H.3
Kikkawa, U.4
Nishizuka, Y.5
Tanaka, C.6
-
66
-
-
0033828387
-
Mitochondrial Ca 2 +homeostasis in the regulation of apoptotic and necrotic cell deaths
-
Zhu LP, Yu XD, Ling S, Brown RA, Kuo TH. Mitochondrial Ca(2 +)homeostasis in the regulation of apoptotic and necrotic cell deaths. Cell Calcium. 2000;28(2):107-17.
-
(2000)
Cell Calcium.
, vol.28
, Issue.2
, pp. 107-117
-
-
Zhu, L.P.1
Yu, X.D.2
Ling, S.3
Brown, R.A.4
Kuo, T.H.5
-
67
-
-
34347337686
-
Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans
-
van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, et al. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genet. 2007;3(6):e108.
-
(2007)
PLoS Genet.
, vol.3
, Issue.6
-
-
Van De Leemput, J.1
Chandran, J.2
Knight, M.A.3
Holtzclaw, L.A.4
Scholz, S.5
Cookson, M.R.6
-
68
-
-
0035838438
-
A novel autosomal dominant spinocerebellar ataxia (SCA16) linked to chromosome 8q22.1-24.1
-
Miyoshi Y, Yamada T, Tanimura M, Taniwaki T, Arakawa K, Ohyagi Y, et al. A novel autosomal dominant spinocerebellar ataxia (SCA16) linked to chromosome 8q22.1-24.1. Neurology. 2001;57(1):96-100.
-
(2001)
Neurology.
, vol.57
, Issue.1
, pp. 96-100
-
-
Miyoshi, Y.1
Yamada, T.2
Tanimura, M.3
Taniwaki, T.4
Arakawa, K.5
Ohyagi, Y.6
-
69
-
-
33749829704
-
The contactin 4 gene locus at 3p26 is a candidate gene of SCA16
-
Miura S, Shibata H, Furuya H, Ohyagi Y, Osoegawa M, Miyoshi Y, et al. The contactin 4 gene locus at 3p26 is a candidate gene of SCA16. Neurology. 2006;67(7):1236-41.
-
(2006)
Neurology.
, vol.67
, Issue.7
, pp. 1236-1241
-
-
Miura, S.1
Shibata, H.2
Furuya, H.3
Ohyagi, Y.4
Osoegawa, M.5
Miyoshi, Y.6
-
70
-
-
38749132487
-
The CNTN4 c.4256C>T mutation is rare in Japanese with inherited spinocerebellar ataxia
-
Tanaka E, Maruyama H, Morino H, Nakajima E, Kawakami H. The CNTN4 c.4256C>T mutation is rare in Japanese with inherited spinocerebellar ataxia. J Neurol Sci. 2008;266(1- 2):180-1.
-
(2008)
J Neurol Sci.
, vol.266
, Issue.1-2
, pp. 180-181
-
-
Tanaka, E.1
Maruyama, H.2
Morino, H.3
Nakajima, E.4
Kawakami, H.5
-
71
-
-
33750944995
-
Inositol 1,4, 5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production
-
Hisatsune C, Kuroda Y, Akagi T, Torashima T, Hirai H, Hashikawa T, et al. Inositol 1, 4, 5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production. J Neurosci. 2006;26(42):10916-24.
-
(2006)
J Neurosci.
, vol.26
, Issue.42
, pp. 10916-10924
-
-
Hisatsune, C.1
Kuroda, Y.2
Akagi, T.3
Torashima, T.4
Hirai, H.5
Hashikawa, T.6
-
72
-
-
0033785307
-
Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4, 5-trisphosphate receptors
-
Fujii S, Matsumoto M, Igarashi K, Kato H, Mikoshiba K. Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1, 4, 5-trisphosphate receptors. Learn Mem. 2000;7 (5):312-20.
-
(2000)
Learn Mem.
, vol.7
, Issue.5
, pp. 312-320
-
-
Fujii, S.1
Matsumoto, M.2
Igarashi, K.3
Kato, H.4
Mikoshiba, K.5
-
73
-
-
0037430766
-
Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP(3) type 1 receptor
-
Nagase T, Ito KI, Kato K, Kaneko K, Kohda K, Matsumoto M, et al. Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP(3) type 1 receptor. Neuroscience. 2003;117(4):821-30.
-
(2003)
Neuroscience.
, vol.117
, Issue.4
, pp. 821-830
-
-
Nagase, T.1
Ito, K.I.2
Kato, K.3
Kaneko, K.4
Kohda, K.5
Matsumoto, M.6
-
74
-
-
48749132328
-
TRPC3 channels are required for synaptic transmission and motor coordination
-
Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, et al. TRPC3 channels are required for synaptic transmission and motor coordination. Neuron. 2008;59(3):392-8.
-
(2008)
Neuron.
, vol.59
, Issue.3
, pp. 392-398
-
-
Hartmann, J.1
Dragicevic, E.2
Adelsberger, H.3
Henning, H.A.4
Sumser, M.5
Abramowitz, J.6
-
75
-
-
66149097030
-
A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice
-
Becker EB, Oliver PL, Glitsch MD, Banks GT, Achilli F, Hardy A, et al. A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proc Natl Acad Sci USA. 2009;106(16):6706-11.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.16
, pp. 6706-6711
-
-
Becker, E.B.1
Oliver, P.L.2
Glitsch, M.D.3
Banks, G.T.4
Achilli, F.5
Hardy, A.6
-
76
-
-
33344454896
-
Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia
-
Walter JT, Alvina K, Womack MD, Chevez C, Khodakhah K. Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. Nat Neurosci. 2006;9(3):389-97.
-
(2006)
Nat Neurosci.
, vol.9
, Issue.3
, pp. 389-397
-
-
Walter, J.T.1
Alvina, K.2
Womack, M.D.3
Chevez, C.4
Khodakhah, K.5
|