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European Journal of Medicinal Chemistry

Volumn 60, Issue , 2013, Pages 469-478

Synthesis and biological evaluation of radioiodinated quinacrine-based derivatives for SPECT imaging of Aβ plaques

(5) Fuchigami, Takeshi a Kobashi, Nobuya a Haratake, Mamoru a Kawasaki, Masao a Nakayama, Morio a

a NAGASAKI UNIVERSITY (Japan)

Author keywords

125I; Acridine; Alzheimer's disease; Amyloid plaques; Quinacrine; Single photon emission computed tomography (SPECT)

Indexed keywords

2 DIMETYLAMINO 9 METHOXY 6 IODO ACRIDINE; 2 METHOXY 9 [4 (DIMETHYL 1 METHYL) N BUTYL]AMINO 6 IODO ACRIDINE; 2,9 DIMETHOXY 6 IODO ACRIDINE; 6 IODO 2 METHOXY 9 METHYLAMINOACRIDINE; 6 IODO 9 DIMETHYLAMINO 2 METHOXYACRIDINE; 6 IODO 9 METHOXYACRIDINE; 9 AMINO 6 IODO 2 METHOXYACRIDINE; ACRIDINE DERIVATIVE; AMYLOID BETA PROTEIN; DIPHENYLAMINE DERIVATIVE; HYDROGEN PEROXIDE; MEPACRINE; UNCLASSIFIED DRUG;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BINDING COMPETITION; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN SLICE; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; IN VIVO STUDY; LIPOPHILICITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRION DISEASE; RADIOIODINATION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TRANSGENIC MOUSE;

ACRIDINES; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; FEMALE; IODINE RADIOISOTOPES; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MOLECULAR STRUCTURE; MYOCARDIAL PERFUSION IMAGING; QUINACRINE;

EID: 84872537289 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.12.020 Document Type: Article

Times cited : (14)

References (35)

1
- 0030841343
- R.W. Carrell, and D.A. Lomas Lancet 350 1997 134 138
- (1997) Lancet , vol.350 , pp. 134-138
- Carrell, R.W.¹ Lomas, D.A.²

2
- 33746377894
- F. Chiti, and C.M. Dobson Annu. Rev. Biochem. 75 2006 333 366
- (2006) Annu. Rev. Biochem. , vol.75 , pp. 333-366
- Chiti, F.¹ Dobson, C.M.²

3
- 73349119086
- P. Mendoza-Espinosa, V. García-González, A. Moreno, R. Castillo, and J. Mas-Oliva Mol. Cell. Biochem. 330 2009 105 120
- (2009) Mol. Cell. Biochem. , vol.330 , pp. 105-120
- Mendoza-Espinosa, P.¹ García-González, V.² Moreno, A.³ Castillo, R.⁴ Mas-Oliva, J.⁵

4
- 0033869349
- D.J. Selkoe Nat. Biotechnol. 18 2000 823 824
- (2000) Nat. Biotechnol. , vol.18 , pp. 823-824
- Selkoe, D.J.¹

5
- 4644283049
- A. Nordberg Lancet Neurol. 3 2004 519 527
- (2004) Lancet Neurol. , vol.3 , pp. 519-527
- Nordberg, A.¹

6
- 0013136066
- D.I. Graham, P.E. Lantos
- S.J. DeArmond, H.A. Kretzschmar, and S.B. Prusiner D.I. Graham, P.E. Lantos, Greenfield's Neuropathology vol. 2 2002 273 323
- (2002) Greenfield's Neuropathology , vol.2 VOL. , pp. 273-323
- Dearmond, S.J.¹ Kretzschmar, H.A.² Prusiner, S.B.³

7
- 33745534523
- A.B. Newberg, N.A. Wintering, K. Plossl, J. Hochold, M.G. Stabin, M. Watson, D. Skovronsky, C.M. Clark, M.P. Kung, and H.F. Kung J. Nucl. Med. 47 2006 748 754
- (2006) J. Nucl. Med. , vol.47 , pp. 748-754
- Newberg, A.B.¹ Wintering, N.A.² Plossl, K.³ Hochold, J.⁴ Stabin, M.G.⁵ Watson, M.⁶ Skovronsky, D.⁷ Clark, C.M.⁸ Kung, M.P.⁹ Kung, H.F.¹⁰

8
- 10744232413
- W.E. Klunk, H. Engler, A. Nordberg, Y. Wang, G. Blomqvist, D.P. Holt, M. Bergstrom, I. Savitcheva, G.F. Huang, S. Estrada, B. Ausen, M.L. Debnath, J. Barletta, J.C. Price, J. Sandell, B.J. Lopresti, A. Wall, P. Koivisto, G. Antoni, C.A. Mathis, and B. Langstrom Ann. Neurol. 55 2004 306 319
- (2004) Ann. Neurol. , vol.55 , pp. 306-319
- Klunk, W.E.¹ Engler, H.² Nordberg, A.³ Wang, Y.⁴ Blomqvist, G.⁵ Holt, D.P.⁶ Bergstrom, M.⁷ Savitcheva, I.⁸ Huang, G.F.⁹ Estrada, S.¹⁰ Ausen, B.¹¹ Debnath, M.L.¹² Barletta, J.¹³ Price, J.C.¹⁴ Sandell, J.¹⁵ Lopresti, B.J.¹⁶ Wall, A.¹⁷ Koivisto, P.¹⁸ Antoni, G.¹⁹ Mathis, C.A.²⁰ Langstrom, B.²¹ more..

9
- 34248579112
- Y. Kudo, N. Okamura, S. Furumoto, M. Tashiro, K. Furukawa, M. Maruyama, M. Itoh, R. Iwata, K. Yanai, and H. Arai J. Nucl. Med. 48 2007 553 561
- (2007) J. Nucl. Med. , vol.48 , pp. 553-561
- Kudo, Y.¹ Okamura, N.² Furumoto, S.³ Tashiro, M.⁴ Furukawa, K.⁵ Maruyama, M.⁶ Itoh, M.⁷ Iwata, R.⁸ Yanai, K.⁹ Arai, H.¹⁰

10
- 38149081191
- C.C. Rowe, U. Ackerman, W. Browne, R. Mulligan, K.L. Pike, G. O'Keefe, H. Tochon-Danguy, G. Chan, S.U. Berlangieri, G. Jones, K.L. Dickinson-Rowe, H.P. Kung, W. Zhang, M.P. Kung, D. Skovronsky, T. Dyrks, G. Holl, S. Krause, M. Friebe, L. Lehman, S. Lindemann, L.M. Dinkelborg, C.L. Masters, and V.L. Villemagne Lancet Neurol. 7 2008 129 135
- (2008) Lancet Neurol. , vol.7 , pp. 129-135
- Rowe, C.C.¹ Ackerman, U.² Browne, W.³ Mulligan, R.⁴ Pike, K.L.⁵ O'Keefe, G.⁶ Tochon-Danguy, H.⁷ Chan, G.⁸ Berlangieri, S.U.⁹ Jones, G.¹⁰ Dickinson-Rowe, K.L.¹¹ Kung, H.P.¹² Zhang, W.¹³ Kung, M.P.¹⁴ Skovronsky, D.¹⁵ Dyrks, T.¹⁶ Holl, G.¹⁷ Krause, S.¹⁸ Friebe, M.¹⁹ Lehman, L.²⁰ more..

11
- 72149125332
- S. Nyberg, M.E. Jönhagen, Z. Cselényi, C. Halldin, P. Julin, H. Olsson, Y. Freund-Levi, J. Andersson, K. Varnäs, S. Svensson, and L. Farde Eur. J. Nucl. Med. Mol. Imaging 36 2009 1859 1863
- (2009) Eur. J. Nucl. Med. Mol. Imaging , vol.36 , pp. 1859-1863
- Nyberg, S.¹ Jönhagen, M.E.² Cselényi, Z.³ Halldin, C.⁴ Julin, P.⁵ Olsson, H.⁶ Freund-Levi, Y.⁷ Andersson, J.⁸ Varnäs, K.⁹ Svensson, S.¹⁰ Farde, L.¹¹

12
- 77953937194
- D.F. Wong, P.B. Rosenberg, Y. Zhou, A. Kumar, V. Raymont, H.T. Ravert, R.F. Dannals, A. Nandi, J.R. Brasic, W. Ye, J. Hilton, C. Lyketsos, H.F. Kung, A.D. Joshi, D.M. Skovronsky, and M.J. Pontecorvo J. Nucl. Med. 51 2010 913 920
- (2010) J. Nucl. Med. , vol.51 , pp. 913-920
- Wong, D.F.¹ Rosenberg, P.B.² Zhou, Y.³ Kumar, A.⁴ Raymont, V.⁵ Ravert, H.T.⁶ Dannals, R.F.⁷ Nandi, A.⁸ Brasic, J.R.⁹ Ye, W.¹⁰ Hilton, J.¹¹ Lyketsos, C.¹² Kung, H.F.¹³ Joshi, A.D.¹⁴ Skovronsky, D.M.¹⁵ Pontecorvo, M.J.¹⁶

13
- 28544450496
- M. Ono, N. Yoshida, K. Ishibashi, M. Haratake, Y. Arano, H. Mori, and M. Nakayama J. Med. Chem. 48 2005 7253 7260
- (2005) J. Med. Chem. , vol.48 , pp. 7253-7260
- Ono, M.¹ Yoshida, N.² Ishibashi, K.³ Haratake, M.⁴ Arano, Y.⁵ Mori, H.⁶ Nakayama, M.⁷

14
- 61349195322
- M. Ono, R. Watanabe, H. Kawashima, T. Kawai, H. Watanabe, M. Haratake, H. Saji, and M. Nakayama Bioorg. Med. Chem. 17 2009 2069 2076
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 2069-2076
- Ono, M.¹ Watanabe, R.² Kawashima, H.³ Kawai, T.⁴ Watanabe, H.⁵ Haratake, M.⁶ Saji, H.⁷ Nakayama, M.⁸

15
- 34547697123
- M. Ono, M. Hori, M. Haratake, T. Tomiyama, H. Mori, and M. Nakayama Bioorg. Med. Chem. 15 2007 6388 6396
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 6388-6396
- Ono, M.¹ Hori, M.² Haratake, M.³ Tomiyama, T.⁴ Mori, H.⁵ Nakayama, M.⁶

16
- 34548535442
- M. Ono, M. Haratake, H. Mori, and M. Nakayama Bioorg. Med. Chem. 15 2007 6802 6809
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 6802-6809
- Ono, M.¹ Haratake, M.² Mori, H.³ Nakayama, M.⁴

17
- 70350075454
- M. Ono, R. Watanabe, H. Kawashima, Y. Cheng, H. Kimura, H. Watanabe, M. Haratake, H. Saji, and M. Nakayama J. Med. Chem. 52 2009 6394 6401
- (2009) J. Med. Chem. , vol.52 , pp. 6394-6401
- Ono, M.¹ Watanabe, R.² Kawashima, H.³ Cheng, Y.⁴ Kimura, H.⁵ Watanabe, H.⁶ Haratake, M.⁷ Saji, H.⁸ Nakayama, M.⁹

18
- 34547115709
- M. Ono, Y. Maya, M. Haratake, K. Ito, H. Mori, and M. Nakayama Biochem. Biophys. Res. Commun. 361 2007 116 121
- (2007) Biochem. Biophys. Res. Commun. , vol.361 , pp. 116-121
- Ono, M.¹ Maya, Y.² Haratake, M.³ Ito, K.⁴ Mori, H.⁵ Nakayama, M.⁶

19
- 61849132762
- Y. Maya, M. Ono, H. Watanabe, M. Haratake, H. Saji, and M. Nakayama Bioconjug. Chem. 20 2009 95 101
- (2009) Bioconjug. Chem. , vol.20 , pp. 95-101
- Maya, Y.¹ Ono, M.² Watanabe, H.³ Haratake, M.⁴ Saji, H.⁵ Nakayama, M.⁶

20
- 33750955461
- M. Ono, Y. Maya, M. Haratake, and M. Nakayama Bioorg. Med. Chem. 15 2007 444 450
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 444-450
- Ono, M.¹ Maya, Y.² Haratake, M.³ Nakayama, M.⁴

21
- 0034001444
- K. Doh-ura, T. Iwaki, and B. Cughey J. Virol. 74 2000 4894 4897
- (2000) J. Virol. , vol.74 , pp. 4894-4897
- Doh-Ura, K.¹ Iwaki, T.² Cughey, B.³

22
- 0035859806
- C. Korth, B.C. May, F.E. Cohen, and S.B. Prusiner Proc. Natl. Acad. Sci. U. S. A. 98 2001 9836 9841
- (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 9836-9841
- Korth, C.¹ May, B.C.² Cohen, F.E.³ Prusiner, S.B.⁴

23
- 0038447100
- A. Barret, F. Tagliavini, G. Forloni, C. Bate, M. Salmona, L. Colombo, A. De Luigi, L. Limido, S. Suardi, G. Rossi, F. Auvré, K.T. Adjou, N. Salès, A. Williams, C. Lasmézas, and J.P. Deslys J. Virol. 77 2003 8462 8469
- (2003) J. Virol. , vol.77 , pp. 8462-8469
- Barret, A.¹ Tagliavini, F.² Forloni, G.³ Bate, C.⁴ Salmona, M.⁵ Colombo, L.⁶ De Luigi, A.⁷ Limido, L.⁸ Suardi, S.⁹ Rossi, G.¹⁰ Auvré, F.¹¹ Adjou, K.T.¹² Salès, N.¹³ Williams, A.¹⁴ Lasmézas, C.¹⁵ Deslys, J.P.¹⁶

24
- 1542405248
- M. Nakajima, T. Yamada, T. Kusuhara, H. Furukawa, M. Takahashi, A. Yamauchi, and Y. Kataoka Dement. Geriatr. Cogn. Disord. 17 2004 158 163
- (2004) Dement. Geriatr. Cogn. Disord. , vol.17 , pp. 158-163
- Nakajima, M.¹ Yamada, T.² Kusuhara, T.³ Furukawa, H.⁴ Takahashi, M.⁵ Yamauchi, A.⁶ Kataoka, Y.⁷

25
- 62149105940
- J. Collinge, M. Gorham, F. Hudson, A. Kennedy, G. Keogh, S. Pal, M. Rossor, P. Rudge, D. Siddique, M. Spyer, D. Thomas, S. Walker, T. Webb, S. Wroe, and J. Darbyshire Lancet Neurol. 8 2009 334 344
- (2009) Lancet Neurol. , vol.8 , pp. 334-344
- Collinge, J.¹ Gorham, M.² Hudson, F.³ Kennedy, A.⁴ Keogh, G.⁵ Pal, S.⁶ Rossor, M.⁷ Rudge, P.⁸ Siddique, D.⁹ Spyer, M.¹⁰ Thomas, D.¹¹ Walker, S.¹² Webb, T.¹³ Wroe, S.¹⁴ Darbyshire, J.¹⁵

26
- 39149121149
- P.J. Song, S. Bernard, P. Sarradin, J. Vergote, C. Barc, S. Chalon, M.P. Kung, H.F. Kung, and D. Guilloteau Nucl. Med. Biol. 35 2008 197 201
- (2008) Nucl. Med. Biol. , vol.35 , pp. 197-201
- Song, P.J.¹ Bernard, S.² Sarradin, P.³ Vergote, J.⁴ Barc, C.⁵ Chalon, S.⁶ Kung, M.P.⁷ Kung, H.F.⁸ Guilloteau, D.⁹

27
- 77952090854
- N. Okamura, Y. Shiga, S. Furumoto, M. Tashiro, Y. Tsuboi, K. Furukawa, K. Yanai, R. Iwata, H. Arai, Y. Kudo, Y. Itoyama, and K. Doh-ura Eur. J. Nucl. Med. Mol. Imaging 37 2010 934 941
- (2010) Eur. J. Nucl. Med. Mol. Imaging , vol.37 , pp. 934-941
- Okamura, N.¹ Shiga, Y.² Furumoto, S.³ Tashiro, M.⁴ Tsuboi, Y.⁵ Furukawa, K.⁶ Yanai, K.⁷ Iwata, R.⁸ Arai, H.⁹ Kudo, Y.¹⁰ Itoyama, Y.¹¹ Doh-Ura, K.¹²

28
- 34547590133
- A.L. Boxer, G.D. Rabinovici, V. Kepe, J. Goldman, A.J. Furst, S.C. Huang, S.L. Baker, J.P. O'neil, H. Chui, M.D. Geschwind, G.W. Small, J.R. Barrio, W. Jagust, and B.L. Miller Neurology 69 2007 283 290
- (2007) Neurology , vol.69 , pp. 283-290
- Boxer, A.L.¹ Rabinovici, G.D.² Kepe, V.³ Goldman, J.⁴ Furst, A.J.⁵ Huang, S.C.⁶ Baker, S.L.⁷ O'Neil, J.P.⁸ Chui, H.⁹ Geschwind, M.D.¹⁰ Small, G.W.¹¹ Barrio, J.R.¹² Jagust, W.¹³ Miller, B.L.¹⁴

29
- 0021341105
- J. Rahimian, E.C. Glass, J.J. Touya, S.F. Akber, L.S. Graham, and L.R. Bennett J. Nucl. Med. 25 1984 31 37
- (1984) J. Nucl. Med. , vol.25 , pp. 31-37
- Rahimian, J.¹ Glass, E.C.² Touya, J.J.³ Akber, S.F.⁴ Graham, L.S.⁵ Bennett, L.R.⁶

30
- 6844249433
- J. Booij, E. Busemann Sokole, M.G. Stabin, A.G. Janssen, K. de Bruin, and E.A. van Royen Eur. J. Nucl. Med. 25 1998 24 30
- (1998) Eur. J. Nucl. Med. , vol.25 , pp. 24-30
- Booij, J.¹ Busemann Sokole, E.² Stabin, M.G.³ Janssen, A.G.⁴ De Bruin, K.⁵ Van Royen, E.A.⁶

31
- 69449086022
- V.L. Villemagne, C.A. McLean, K. Reardon, A. Boyd, V. Lewis, G. Klug, G. Jones, D. Baxendale, C.L. Masters, C.C. Rowe, and S.J. Collins J. Neurol. Neurosurg. Psychiatry 80 2009 998 1001
- (2009) J. Neurol. Neurosurg. Psychiatry , vol.80 , pp. 998-1001
- Villemagne, V.L.¹ McLean, C.A.² Reardon, K.³ Boyd, A.⁴ Lewis, V.⁵ Klug, G.⁶ Jones, G.⁷ Baxendale, D.⁸ Masters, C.L.⁹ Rowe, C.C.¹⁰ Collins, S.J.¹¹

32
- 0009412958
- Academic Press New York p. 326
- H. Surrey Name Reactions in Organic Chemistry 1961 Academic Press New York p. 326
- (1961) Name Reactions in Organic Chemistry
- Surrey, H.¹

33
- 67849083569
- V.W. Pike Trends Pharmacol. Sci. 30 2009 431 440
- (2009) Trends Pharmacol. Sci. , vol.30 , pp. 431-440
- Pike, V.W.¹

34
- 0344121272
- R.N. Waterhouse Mol. Imaging Biol. 5 2003 376 389
- (2003) Mol. Imaging Biol. , vol.5 , pp. 376-389
- Waterhouse, R.N.¹

35
- 0037448350
- Z.P. Zhuang, M.P. Kung, A. Wilson, C.W. Lee, K. Plössl, C. Hou, D.M. Holtzman, and H.F. Kung J. Med. Chem. 46 2003 237 243
- (2003) J. Med. Chem. , vol.46 , pp. 237-243
- Zhuang, Z.P.¹ Kung, M.P.² Wilson, A.³ Lee, C.W.⁴ Plössl, K.⁵ Hou, C.⁶ Holtzman, D.M.⁷ Kung, H.F.⁸

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