Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells

BMC Systems Biology

Volumn 7, Issue , 2013, Pages

  Cho, Hyunju ^a   Wu, Ming ^a   Zhang, Linxia ^a   Thompson, Ryan ^b   Nath, Aritro ^b   Chan, Christina ^a,b,c  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Michigan State University   (United States)

Author keywords

ATF4; CREB1; Discrete dynamic model; Palmitate induced ER stress; Signal transduction

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, HUMAN; CREB1 PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PALMITIC ACID; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; CELL STRAIN HEPG2; COMPUTER SIMULATION; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; BLOTTING, WESTERN; COMPUTER SIMULATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; MODELS, BIOLOGICAL; PALMITIC ACID; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MLCS; MLOWN;

EID: 84872445186     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-7-9     Document Type: Article

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