Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

EMBO Molecular Medicine

Volumn 4, Issue 12, 2012, Pages 1261-1275

  Schickel, Jean Nicolas ^a   Pasquali, Jean Louis ^a,b,c   Soley, Anne ^a,b   Knapp, Anne Marie ^a,b   Decossas, Marion ^a   Kern, Aurélie ^b   Fauny, Jean Daniel ^a   Marcellin, Luc ^c   Korganow, Anne Sophie ^a,b,c   Martin, Thierry ^a,b,c   Soulas Sprauel, Pauline ^a,b,c  

^a INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c UNIVERSITY HOSPITAL OF STRASBOURG   (France)

Author keywords

Autoimmunity; B cells; Carabin; Mouse models; Systemic lupus erythematosus

Indexed keywords

B LYMPHOCYTE RECEPTOR; BREAKPOINT CLUSTER REGION PROTEIN; CARABIN; DNA; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CARABIN DEFICIENCY; CELL FUNCTION; CONTROLLED STUDY; CPG ISLAND; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; CARRIER PROTEINS; COHORT STUDIES; DNA; HUMANS; MICE; MICE, INBRED NZB; MICE, INBRED STRAINS; PHOSPHORYLATION; PROSPECTIVE STUDIES; RECEPTORS, ANTIGEN, B-CELL; TOLL-LIKE RECEPTOR 9; TRANSFECTION;

EID: 84872415986     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201595     Document Type: Article

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