Molecular approaches for structural characterization of a new potassium channel blocker from Tityus stigmurus venom: CDNA cloning, homology modeling, dynamic simulations and docking

Biochemical and Biophysical Research Communications

Volumn 430, Issue 1, 2013, Pages 113-118

  Almeida, Diego Dantas ^a   Torres, Taffarel Melo ^a   Barbosa, Euzébio Guimarães ^a   Lima, João Paulo Matos Santos ^a   De Freitas Fernandes Pedrosa, Matheus ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Potassium channel blocker; Scorpion; Structure; Tityus stigmurus; Toxin

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; TITYUS TOXIN; TSTI 003C; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; DNA SEQUENCE; DRUG STRUCTURE; MOLECULAR CLONING; MOLECULAR DOCKING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSCRIPTOMICS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MODELS, CHEMICAL; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; PROTEIN CONFORMATION; SCORPION VENOMS; SCORPIONS;

RATTUS; SCORPIONES; TITYUS STIGMURUS;

EID: 84872381844     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.044     Document Type: Article

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