Wide phylogenetic distribution of Scorpine and long-chain β-KTx-like peptides in scorpion venoms: Identification of "orphan" components

Peptides

Volumn 28, Issue 1, 2007, Pages 31-37

  Diego García, Elia ^a   Schwartz, Elisabeth F ^a,b   D'Suze, Gina ^a,c   González, Sergio A Román ^a   Batista, Cesar V F ^a   García, Blanca I ^a,d   de la Vega, Ricardo C Rodríguez ^a   Possani, Lourival D ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b UNIVERSITY OF BRASILIA   (Brazil)

^c INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^d Instituto Bioclon SA de CV   (Mexico)

Author keywords

Amino acid sequence determination; cDNA cloning; Scorpion toxins

Indexed keywords

BETA KTX LIKE POLYPEPTIDE; BMTXK BETA PEPTIDE; COMPLEMENTARY DNA; PEPTIDE; SCORPINE; SCORPION VENOM;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BUTHIDAE; FAMILIA; GENUS; HADRURUS GERTSCHI; IURIDAE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; SCORPION; SEQUENCE ANALYSIS; TITYUS COSTATUS; TITYUS DISCREPANS; TITYUS TRIVITTATUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDES; PHYLOGENY; SCORPION VENOMS; SCORPIONS; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

BUTHIDA; BUTHIDAE; HADRURUS; IURIDA; IURIDAE; SCORPIONES; SCORPIONIDAE; TITYUS; TITYUS COSTATUS; TITYUS DISCREPANS;

EID: 33845647560     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.06.012     Document Type: Article

References (25)

1. Batista C.V.F., del Pozo L., Zamudio F.Z., Contreras S., Becerril B., Wanke E., et al. Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins. J Chromatogr B 803 (2004) 55-66
2. Batista C.V.F., D'Suze G., Gómez-Lagunas F., Zamudio F.Z., Encarnación S., Sevcik C., et al. Protemic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins. Proteomics 6 (2006) 3718-3727
3. Brune D.C. Alkylation of cysteine with acrylamide for proteins sequence analysis. Anal Biochem 207 (1992) 285-290
4. Cao Z., Xiao F., Peng F., Jiang D., Mao X., Liu H., et al. Expression, purification and functional characterization of a recombinant scorpion venom peptide BmTXKbeta. Peptides 24 (2003) 187-192
5. Conde R., Zamudio F.Z., Rodriguez M.H., and Possani L.D. Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom. FEBS Lett 471 (2000) 165-168
6. Coronas F.V., de Roodt A.R., Portugal T.O., Zamudio F.Z., Batista C.V., Gomez-Lagunas F., et al. Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus. Toxicon 41 (2003) 173-179
7. da Silva W.D., and Kipnis T.L. Venoms. Encyclopedia of life sciences (2001), John Wiley & Sons, Ltd., Chichester 10.1038/npg.els.0000939
8. Diego-Garcia E., Batista C.V., Garcia-Gomez B.I., Lucas S., Candido D.M., Gomez-Lagunas F., et al. The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function. Toxicon 45 (2005) 273-283
9. Jungo F., and Bairoch A. Tox-Prot, the toxin protein annotation program of the Swiss-Prot knowledgebase. Toxicon 45 (2005) 293-301
10. Kuhn-Nentwig L. Antimicrobial and cytolytic peptides of venomous arthropods. Cell Mol Life Sci 60 (2003) 2651-2668
11. + channels. FEBS Lett 431 (1998) 375-380
12. Mouhat S., Jouirou B., Mosbah A., De Waard M., and Sabatier J.M. Diversity of folds in animal toxins acting on ion channels. Biochem J 378 (2004) 717-726
13. Nascimento D.G., Rates B., Santos D.M., Verano-Braga T., Barbosa-Silva A., Dutra A.A., et al. Moving pieces in a taxonomic puzzle: venom 2D-LC/MS and data clustering analyses to infer phylogenetic relationships in some scorpions from the Buthidae family (Scorpiones). Toxicon 47 (2006) 628-639
14. + channels. Toxicon 7 (1999) 651-660
15. Notredame C., Higgins D.G., and Heringa J. T-Coffee: a novel method for fast and accurate multiple sequence alignment. J Mol Biol 302 (2000) 205-217
16. +-channels. Toxicon 43 (2004) 865-875
17. +-channels: biodiversity, structure-function and evolution. Toxicon 46 (2005) 831-844
18. + channels blocked by alpha-dendrotoxin in synaptosomes. Proc Natl Acad Sci USA 91 (1994) 1475-1479
19. Tan P.J., Veeramani A., Srinivasan K.N., Ranganathan S., and Brusic V. SCORPION2: a database for structure-function analysis of scorpion toxins. Toxicon 47 (2006) 356-363
20. Torres-Larios A., Gurrola G.B., Zamudio F.Z., and Possani L.D. Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus. Eur J Biochem 267 (2000) 5023-5031
21. Tytgat J., Chandy K.G., Garcia M.L., Gutman G.A., Martin-Eauclaire M.F., van der Walt J.J., et al. A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. Trends Pharmacol Sci 20 (1999) 444-447
22. Zeng X.C., Corzo G., and Hahin R. Scorpion venom peptides without disulfide bridges. IUBMB Life 57 (2005) 13-21
23. Zhijian C., Feng L., Yingliang W., Xin M., and Wenxin L. Genetic mechanisms of scorpion venom peptide diversification. Toxicon 47 (2006) 348-355
24. Zhu S., Li W., Zeng X., Jiang D., Mao X., and Liu H. Molecular cloning and sequencing of two 'short chain' and two 'long chain' K(+) channel-blocking peptides from the Chinese scorpion Buthus martensii Karsch. FEBS Lett 457 (1999) 509-514
25. Zhu S., and Tytgat J. The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition. Cell Mol Life Sci 61 (2004) 1751-1763