A Yeast Purification System for Human Translation Initiation Factors eIF2 and eIF2Bε and Their Use in the Diagnosis of CACH/VWM Disease

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  de Almeida, Rogerio A ^a   Fogli, Anne ^b,c,d   Gaillard, Marina ^b   Scheper, Gert C ^e,h   Boesflug Tanguy, Odile ^f,g   Pavitt, Graham D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSERM   (France)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

^d UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f HÔPITAL ROBERT DEBRÉ   (France)

^g UNIVERSITÉ PARIS DESCARTES   (France)

^h CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; INITIATION FACTOR 2; INITIATION FACTOR 2BETA EPSILON; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; BIOENGINEERING; CARBOXY TERMINAL SEQUENCE; CHILDHOOD ATAXIA WITH CENTRAL NERVOUS SYSTEM HYPOMYELINATION; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOCYTE; MOLECULAR PATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PURIFICATION; VANISHING WHITE MATTER LEUKOENCEPHALOPATHY; YEAST CELL;

CATALYTIC DOMAIN; EUKARYOTIC INITIATION FACTOR-2; EUKARYOTIC INITIATION FACTOR-2B; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LEUKOENCEPHALOPATHIES; MUTATION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; MAMMALIA; RATTUS;

EID: 84872381683     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053958     Document Type: Article

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