-
1
-
-
0003611323
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Adams, A., D. E. Gottschling, C. A. Kaiser, and T. Stearns. 1998. Methods in yeast genetics: a Cold Spring Harbor Laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1998)
Methods in yeast genetics: A Cold Spring Harbor Laboratory course manual
-
-
Adams, A.1
Gottschling, D.E.2
Kaiser, C.A.3
Stearns, T.4
-
2
-
-
33744957161
-
Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon
-
Alone, P. V., and T. E. Dever. 2006. Direct binding of translation initiation factor eIF2γ-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon. J. Biol. Chem. 281:12636-12644.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 12636-12644
-
-
Alone, P.V.1
Dever, T.E.2
-
3
-
-
31344470389
-
Diversification of catalytic activities and ligand interactions in the protein fold shared by the sugar isomerases, eIF2B, DeoR transcription factors, acyl-CoA transferases and methenyltetrahydrofolate synthetase
-
Anantharaman, V., and L. Aravind. 2006. Diversification of catalytic activities and ligand interactions in the protein fold shared by the sugar isomerases, eIF2B, DeoR transcription factors, acyl-CoA transferases and methenyltetrahydrofolate synthetase. J. Mol. Biol. 356:823-842.
-
(2006)
J. Mol. Biol
, vol.356
, pp. 823-842
-
-
Anantharaman, V.1
Aravind, L.2
-
4
-
-
0033638335
-
Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A: EEF1Bα
-
Andersen, G. R., L. Pedersen, L. Valente, I. Chatterjee, T. G. Kinzy, M. Kjeldgaard, and J. Nyborg. 2000. Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A: eEF1Bα. Mol. Cell 6:1261-1266.
-
(2000)
Mol. Cell
, vol.6
, pp. 1261-1266
-
-
Andersen, G.R.1
Pedersen, L.2
Valente, L.3
Chatterjee, I.4
Kinzy, T.G.5
Kjeldgaard, M.6
Nyborg, J.7
-
6
-
-
0033559265
-
Conserved bipartite motifs in yeast eIF5 and eIF2Bε, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2
-
Asano, K., T. Krishnamoorthy, L. Phan, G. D. Pavitt, and A. G. Hinnebusch. 1999. Conserved bipartite motifs in yeast eIF5 and eIF2Bε, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2. EMBO J. 18:1673-1688.
-
(1999)
EMBO J
, vol.18
, pp. 1673-1688
-
-
Asano, K.1
Krishnamoorthy, T.2
Phan, L.3
Pavitt, G.D.4
Hinnebusch, A.G.5
-
7
-
-
18444406259
-
Analysis and reconstitution of translation initiation in vitro
-
Asano, K., L. Phan, T. Krishnamoorthy, G. D. Pavitt, E. Gomez, E. M. Hannig, J. Nika, T. F. Donahue, H. K. Huang, and A. G. Hinnebusch. 2002. Analysis and reconstitution of translation initiation in vitro. Methods Enzymol. 351:221-247.
-
(2002)
Methods Enzymol
, vol.351
, pp. 221-247
-
-
Asano, K.1
Phan, L.2
Krishnamoorthy, T.3
Pavitt, G.D.4
Gomez, E.5
Hannig, E.M.6
Nika, J.7
Donahue, T.F.8
Huang, H.K.9
Hinnebusch, A.G.10
-
8
-
-
33746713880
-
The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5
-
Bieniossek, C., P. Schutz, M. Bumann, A. Limacher, I. Uson, and U. Baumann. 2006. The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5. J. Mol. Biol. 360:457-465.
-
(2006)
J. Mol. Biol
, vol.360
, pp. 457-465
-
-
Bieniossek, C.1
Schutz, P.2
Bumann, M.3
Limacher, A.4
Uson, I.5
Baumann, U.6
-
9
-
-
1542368830
-
Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue
-
Boesen, T., S. S. Mohammad, G. D. Pavitt, and G. R. Andersen. 2004. Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue. J. Biol. Chem. 279: 10584-10592.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 10584-10592
-
-
Boesen, T.1
Mohammad, S.S.2
Pavitt, G.D.3
Andersen, G.R.4
-
10
-
-
0033179296
-
GEFs: Structural basis for their activation of small GTP-binding proteins
-
Cherfils, J., and P. Chardin. 1999. GEFs: structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24:306-311.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 306-311
-
-
Cherfils, J.1
Chardin, P.2
-
11
-
-
0025853453
-
Complex formation by positive and negative translational regulators of GCN4
-
Cigan, A. M., M. Foiani, E. M. Hannig, and A. G. Hinnebusch. 1991. Complex formation by positive and negative translational regulators of GCN4. Mol. Cell. Biol. 11:3217-3228.
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 3217-3228
-
-
Cigan, A.M.1
Foiani, M.2
Hannig, E.M.3
Hinnebusch, A.G.4
-
12
-
-
0030907057
-
Using GCN4 as a reporter of eIF2α phosphorylation and translational regulation in yeast
-
Dever, T. E. 1997. Using GCN4 as a reporter of eIF2α phosphorylation and translational regulation in yeast. Methods 11:403-417.
-
(1997)
Methods
, vol.11
, pp. 403-417
-
-
Dever, T.E.1
-
14
-
-
16244373354
-
+ astrocyte generation in vanishing white matter leukodystrophy
-
+ astrocyte generation in vanishing white matter leukodystrophy. Nat. Med. 11:277-283.
-
(2005)
Nat. Med
, vol.11
, pp. 277-283
-
-
Dietrich, J.1
Lacagnina, M.2
Gass, D.3
Richfield, E.4
Mayer-Proschel, M.5
Noble, M.6
Torres, C.7
Proschel, C.8
-
15
-
-
0029022224
-
Mutations in GCD11, the structural gene for eIF-2 gamma in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis
-
Dorris, D. R., F. L. Erickson, and E. M. Hannig. 1995. Mutations in GCD11, the structural gene for eIF-2 gamma in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis. EMBO J. 14:2239-2249.
-
(1995)
EMBO J
, vol.14
, pp. 2239-2249
-
-
Dorris, D.R.1
Erickson, F.L.2
Hannig, E.M.3
-
16
-
-
0029858531
-
Ligand interactions with eukaryotic translation initiation factor 2: Role of the γ-subunit
-
Erickson, F. L., and E. M. Hannig. 1996. Ligand interactions with eukaryotic translation initiation factor 2: role of the γ-subunit. EMBO J. 15:6311-6320.
-
(1996)
EMBO J
, vol.15
, pp. 6311-6320
-
-
Erickson, F.L.1
Hannig, E.M.2
-
17
-
-
0035004387
-
Minimum requirements for the function of eukaryotic translation initiation factor 2
-
Erickson, F. L., J. Nika, S. Rippel, and E. M. Hannig. 2001. Minimum requirements for the function of eukaryotic translation initiation factor 2. Genetics 158:123-132.
-
(2001)
Genetics
, vol.158
, pp. 123-132
-
-
Erickson, F.L.1
Nika, J.2
Rippel, S.3
Hannig, E.M.4
-
18
-
-
32544438040
-
The large spectrum of eIF2B-related diseases
-
Fogli, A., and O. Boespflug-Tanguy. 2006. The large spectrum of eIF2B-related diseases. Biochem. Soc. Trans. 34:22-29.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 22-29
-
-
Fogli, A.1
Boespflug-Tanguy, O.2
-
19
-
-
4043171216
-
Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients
-
Fogli, A., R. Schiffmann, L. Hugendubler, P. Combes, E. Bertini, D. Rodriguez, S. R. Kimball, and O. Boespflug-Tanguy. 2004. Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients. Eur. J. Hum. Genet. 12:561-566.
-
(2004)
Eur. J. Hum. Genet
, vol.12
, pp. 561-566
-
-
Fogli, A.1
Schiffmann, R.2
Hugendubler, L.3
Combes, P.4
Bertini, E.5
Rodriguez, D.6
Kimball, S.R.7
Boespflug-Tanguy, O.8
-
20
-
-
5044229348
-
Molecular mechanisms of translational control
-
Gebauer, F., and M. W. Hentze. 2004. Molecular mechanisms of translational control. Nat. Rev. Mol. Cell Biol. 5:827-835.
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 827-835
-
-
Gebauer, F.1
Hentze, M.W.2
-
21
-
-
0036790688
-
Characterization of the minimal catalytic domain within eIF2B: The guanine-nucleotide exchange factor for translation initiation
-
Gomez, E., S. S. Mohammad, and G. D. Pavitt. 2002. Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. EMBO J. 21:5292-5301.
-
(2002)
EMBO J
, vol.21
, pp. 5292-5301
-
-
Gomez, E.1
Mohammad, S.S.2
Pavitt, G.D.3
-
22
-
-
0034024628
-
Identification of domains and residues within the ε subunit of eukaryotic translation initiation factor 2B (eIF2Bε) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation
-
Gomez, E., and G. D. Pavitt. 2000. Identification of domains and residues within the ε subunit of eukaryotic translation initiation factor 2B (eIF2Bε) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation. Mol. Cell. Biol. 20:3965-3976.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 3965-3976
-
-
Gomez, E.1
Pavitt, G.D.2
-
23
-
-
27144510561
-
Translational regulation of GCN4 and the general amino acid control of yeast
-
Hinnebusch, A. G. 2005. Translational regulation of GCN4 and the general amino acid control of yeast. Annu. Rev. Microbiol. 59:407-450.
-
(2005)
Annu. Rev. Microbiol
, vol.59
, pp. 407-450
-
-
Hinnebusch, A.G.1
-
24
-
-
0030886675
-
GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae
-
Huang, H. K., H. Yoon, E. M. Hannig, and T. F. Donahue. 1997. GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae. Genes Dev. 11:2396-2413.
-
(1997)
Genes Dev
, vol.11
, pp. 2396-2413
-
-
Huang, H.K.1
Yoon, H.2
Hannig, E.M.3
Donahue, T.F.4
-
25
-
-
33646068185
-
Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients
-
Kantor, L., H. P. Harding, D. Ron, R. Schiffmann, C. R. Kaneski, S. R. Kimball, and O. Elroy-Stein. 2005. Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients. Hum. Genet. 118:99-106.
-
(2005)
Hum. Genet
, vol.118
, pp. 99-106
-
-
Kantor, L.1
Harding, H.P.2
Ron, D.3
Schiffmann, R.4
Kaneski, C.R.5
Kimball, S.R.6
Elroy-Stein, O.7
-
26
-
-
0030025671
-
The structure of the Escherichia coli EF-Tu EF-Ts complex at 2.5A resolution
-
Kawashima, T., C. Berthet-Colominas, M. Wulff, S. Cusack, and R. Leberman. 1996. The structure of the Escherichia coli EF-Tu EF-Ts complex at 2.5A resolution. Nature 379:511-518.
-
(1996)
Nature
, vol.379
, pp. 511-518
-
-
Kawashima, T.1
Berthet-Colominas, C.2
Wulff, M.3
Cusack, S.4
Leberman, R.5
-
27
-
-
34447515801
-
Purification of FLAG-tagged eukaryotic initiation factor 2B complexes, sub-complexes and fragments from Saccharomyces cerevisiae
-
in press
-
Mohammad-Qureshi, S. S., R. Haddad, K. S. Palmer, J. P. Richardson, E. Gomez, and G. D. Pavitt. Purification of FLAG-tagged eukaryotic initiation factor 2B complexes, sub-complexes and fragments from Saccharomyces cerevisiae. Methods Enzymol., in press.
-
Methods Enzymol
-
-
Mohammad-Qureshi, S.S.1
Haddad, R.2
Palmer, K.S.3
Richardson, J.P.4
Gomez, E.5
Pavitt, G.D.6
-
28
-
-
28844478867
-
eIF2B, a mediator of general and gene-specific translational control
-
Pavitt, G. D. 2005. eIF2B, a mediator of general and gene-specific translational control. Biochem. Soc. Trans. 33:1487-1492.
-
(2005)
Biochem. Soc. Trans
, vol.33
, pp. 1487-1492
-
-
Pavitt, G.D.1
-
29
-
-
0028926048
-
Protein-protein interactions: Methods for detection and analysis
-
Phizicky, E. M., and S. Fields. 1995. Protein-protein interactions: methods for detection and analysis. Microbiol. Rev. 59:94-123.
-
(1995)
Microbiol. Rev
, vol.59
, pp. 94-123
-
-
Phizicky, E.M.1
Fields, S.2
-
30
-
-
0346243924
-
Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
-
Renault, L., B. Guibert, and J. Cherfils. 2003. Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor. Nature 426:525-530.
-
(2003)
Nature
, vol.426
, pp. 525-530
-
-
Renault, L.1
Guibert, B.2
Cherfils, J.3
-
31
-
-
1542344340
-
Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity
-
Richardson, J. P., S. S. Mohammad, and G. D. Pavitt. 2004. Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity. Mol. Cell. Biol. 24:2352-2363.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 2352-2363
-
-
Richardson, J.P.1
Mohammad, S.S.2
Pavitt, G.D.3
-
32
-
-
1642304746
-
X-ray structure of translation initiation factor eIF2γ: Implications for tRNA and eIF2α binding
-
Roll-Mecak, A., P. Alone, C. Cao, T. E. Dever, and S. K. Burley. 2004. X-ray structure of translation initiation factor eIF2γ: implications for tRNA and eIF2α binding. J. Biol. Chem. 279:10634-10642.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 10634-10642
-
-
Roll-Mecak, A.1
Alone, P.2
Cao, C.3
Dever, T.E.4
Burley, S.K.5
-
33
-
-
33749340583
-
An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation
-
Singh, C. R., B. Lee, T. Udagawa, S. S. Mohammad-Qureshi, Y. Yamamoto, G. D. Pavitt, and K. Asano. 2006. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation. EMBO J. 25:4537-4546.
-
(2006)
EMBO J
, vol.25
, pp. 4537-4546
-
-
Singh, C.R.1
Lee, B.2
Udagawa, T.3
Mohammad-Qureshi, S.S.4
Yamamoto, Y.5
Pavitt, G.D.6
Asano, K.7
-
34
-
-
33748350921
-
Structure of archaeal translational initiation factor 2βγ-GDP reveals significant conformational change of the β-subunit and switch 1 region
-
Sokabe, M., M. Yao, N. Sakai, S. Toya, and I. Tanaka. 2006. Structure of archaeal translational initiation factor 2βγ-GDP reveals significant conformational change of the β-subunit and switch 1 region. Proc. Natl. Acad. Sci. USA 103:13016-13021.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13016-13021
-
-
Sokabe, M.1
Yao, M.2
Sakai, N.3
Toya, S.4
Tanaka, I.5
-
35
-
-
0032538347
-
Invasion of the nucleotide snatchers: Structural insights into the mechanism of G protein GEFs
-
Sprang, S. R., and D. E. Coleman. 1998. Invasion of the nucleotide snatchers: structural insights into the mechanism of G protein GEFs. Cell 95:155-158.
-
(1998)
Cell
, vol.95
, pp. 155-158
-
-
Sprang, S.R.1
Coleman, D.E.2
-
36
-
-
33846027894
-
Structural evidence for a common intermediate in small G protein-GEF reactions
-
Thomas, C., I. Fricke, A. Scrima, A. Berken, and A. Wittinghofer. 2007. Structural evidence for a common intermediate in small G protein-GEF reactions. Mol. Cell 25:141-149.
-
(2007)
Mol. Cell
, vol.25
, pp. 141-149
-
-
Thomas, C.1
Fricke, I.2
Scrima, A.3
Berken, A.4
Wittinghofer, A.5
-
37
-
-
0031574072
-
The CLUSTAL_X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson, J. D., T. J. Gibson, F. Plewniak, F. Jeanmougin, and D. G. Higgins. 1997. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
38
-
-
0242522401
-
eIF2B-related disorders: Antenatal onset and involvement of multiple organs
-
van der Knaap, M. S., C. G. van Berkel, J. Herms, R. van Coster, M. Baethmann, S. Naidu, E. Boltshauser, M. A. Willemsen, B. Plecko, G. F. Hoffmann, C. G. Proud, G. C. Scheper, and J. C. Prank. 2003. eIF2B-related disorders: antenatal onset and involvement of multiple organs. Am. J. Hum. Genet. 73:1199-1207.
-
(2003)
Am. J. Hum. Genet
, vol.73
, pp. 1199-1207
-
-
van der Knaap, M.S.1
van Berkel, C.G.2
Herms, J.3
van Coster, R.4
Baethmann, M.5
Naidu, S.6
Boltshauser, E.7
Willemsen, M.A.8
Plecko, B.9
Hoffmann, G.F.10
Proud, C.G.11
Scheper, G.C.12
Prank, J.C.13
-
39
-
-
33747816491
-
Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease
-
van Kollenburg, B., J. van Dijk, J. Garbern, A. A. Thomas, G. C. Scheper, J. M. Powers, and M. S. van der Knaap. 2006. Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease. J. Neuropathol. Exp. Neurol. 65:707-715.
-
(2006)
J. Neuropathol. Exp. Neurol
, vol.65
, pp. 707-715
-
-
van Kollenburg, B.1
van Dijk, J.2
Garbern, J.3
Thomas, A.A.4
Scheper, G.C.5
Powers, J.M.6
van der Knaap, M.S.7
-
40
-
-
33646173651
-
Crystal structure of the C-terminal domain of S. cerevisiae eIF5
-
Wei, Z., Y. Xue, H. Xu, and W. Gong. 2006. Crystal structure of the C-terminal domain of S. cerevisiae eIF5. J. Mol. Biol. 359:1-9.
-
(2006)
J. Mol. Biol
, vol.359
, pp. 1-9
-
-
Wei, Z.1
Xue, Y.2
Xu, H.3
Gong, W.4
-
41
-
-
0024381444
-
Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability
-
Wek, R. C., B. M. Jackson, and A. G. Hinnebusch. 1989. Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability. Proc. Natl. Acad. Sci. USA 86:4579-4583.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 4579-4583
-
-
Wek, R.C.1
Jackson, B.M.2
Hinnebusch, A.G.3
-
42
-
-
0025330827
-
Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression
-
Wek, R. C., M. Ramirez, B. M. Jackson, and A. G. Hinnebusch. 1990. Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression. Mol. Cell. Biol. 10:2820-2831.
-
(1990)
Mol. Cell. Biol
, vol.10
, pp. 2820-2831
-
-
Wek, R.C.1
Ramirez, M.2
Jackson, B.M.3
Hinnebusch, A.G.4
-
43
-
-
28044445673
-
The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G
-
Yamamoto, Y., C. R. Singh, A. Marintchev, N. S. Hall, E. M. Hannig, G. Wagner, and K. Asano. 2005. The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G. Proc. Natl. Acad. Sci. USA 102:16164-16169.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16164-16169
-
-
Yamamoto, Y.1
Singh, C.R.2
Marintchev, A.3
Hall, N.S.4
Hannig, E.M.5
Wagner, G.6
Asano, K.7
-
44
-
-
33644790001
-
Structural switch of the γ subunit in an archaeal aIF2 αγ heterodimer
-
Yatime, L., Y. Mechulam, S. Blanquet, and E. Schmitt. 2006. Structural switch of the γ subunit in an archaeal aIF2 αγ heterodimer. Structure 14:119-128.
-
(2006)
Structure
, vol.14
, pp. 119-128
-
-
Yatime, L.1
Mechulam, Y.2
Blanquet, S.3
Schmitt, E.4
|