-
1
-
-
0025728532
-
A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae
-
Abastado, J. P., P. F. Miller, and A. G. Hinnebusch. 1991. A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae. New Biol. 3:511-524.
-
(1991)
New Biol
, vol.3
, pp. 511-524
-
-
Abastado, J.P.1
Miller, P.F.2
Hinnebusch, A.G.3
-
2
-
-
1642553650
-
Defective translational control facilitates vesicular stomatitis virus oncolysis
-
Balachandran, S., and G. N. Barber. 2004. Defective translational control facilitates vesicular stomatitis virus oncolysis. Cancer Cell 5:51-65.
-
(2004)
Cancer Cell
, vol.5
, pp. 51-65
-
-
Balachandran, S.1
Barber, G.N.2
-
3
-
-
0033679958
-
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
-
Balachandran, S., et al. 2000. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. Immunity 13:129-141.
-
(2000)
Immunity
, vol.13
, pp. 129-141
-
-
Balachandran, S.1
-
4
-
-
27944432605
-
VSV-tumor selective replication and protein translation
-
Barber, G. N. 2005. VSV-tumor selective replication and protein translation. Oncogene 24:7710-7719.
-
(2005)
Oncogene
, vol.24
, pp. 7710-7719
-
-
Barber, G.N.1
-
5
-
-
0025107684
-
Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
-
De Benedetti, A., and R. E. Rhoads. 1990. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology. Proc. Natl. Acad. Sci. U. S. A. 87:8212-8216.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 8212-8216
-
-
De Benedetti, A.1
Rhoads, R.E.2
-
6
-
-
0026556814
-
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
-
Dever, T. E., et al. 1992. Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast. Cell 68:585-596.
-
(1992)
Cell
, vol.68
, pp. 585-596
-
-
Dever, T.E.1
-
7
-
-
0029118217
-
Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells
-
Donze, O., R. Jagus, A. E. Koromilas, J. W. Hershey, and N. Sonenberg. 1995. Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells. EMBO J. 14:3828-3834.
-
(1995)
EMBO J
, vol.14
, pp. 3828-3834
-
-
Donze, O.1
Jagus, R.2
Koromilas, A.E.3
Hershey, J.W.4
Sonenberg, N.5
-
8
-
-
0030924304
-
Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells
-
Fabian, J. R., S. R. Kimball, N. K. Heinzinger, and L. S. Jefferson. 1997. Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells. J. Biol. Chem. 272:12359-12365.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12359-12365
-
-
Fabian, J.R.1
Kimball, S.R.2
Heinzinger, N.K.3
Jefferson, L.S.4
-
9
-
-
0032103789
-
Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cells
-
Fabian, J. R., S. R. Kimball, and L. S. Jefferson. 1998. Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cells. Protein Expr. Purif. 13:16-22.
-
(1998)
Protein Expr. Purif.
, vol.13
, pp. 16-22
-
-
Fabian, J.R.1
Kimball, S.R.2
Jefferson, L.S.3
-
10
-
-
0036790688
-
Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation
-
Gomez, E., S. S. Mohammad, and G. D. Pavitt. 2002. Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. EMBO J. 21:5292-5301.
-
(2002)
EMBO J
, vol.21
, pp. 5292-5301
-
-
Gomez, E.1
Mohammad, S.S.2
Pavitt, G.D.3
-
11
-
-
0023797126
-
Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function
-
Hannig, E. M., and A. G. Hinnebusch. 1988. Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function. Mol. Cell. Biol. 8:4808-4820.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 4808-4820
-
-
Hannig, E.M.1
Hinnebusch, A.G.2
-
12
-
-
0033634654
-
Regulated translation initiation controls stressinduced gene expression in mammalian cells
-
Harding, H. P., et al. 2000. Regulated translation initiation controls stressinduced gene expression in mammalian cells. Mol. Cell 6:1099-1108.
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
-
13
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding, H. P., Y. Zhang, and D. Ron. 1999. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397:271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
14
-
-
0027490295
-
Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2
-
Hinnebusch, A. G. 1993. Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2. Mol. Microbiol. 10:215-223.
-
(1993)
Mol. Microbiol.
, vol.10
, pp. 215-223
-
-
Hinnebusch, A.G.1
-
15
-
-
33646068185
-
Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients
-
Kantor, L., et al. 2005. Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients. Hum. Genet. 118:99-106.
-
(2005)
Hum. Genet.
, vol.118
, pp. 99-106
-
-
Kantor, L.1
-
16
-
-
0028815704
-
Regulation of the interferon-induced PKR: can viruses cope?
-
Katze, M. G. 1995. Regulation of the interferon-induced PKR: can viruses cope? Trends Microbiol. 3:75-78.
-
(1995)
Trends Microbiol
, vol.3
, pp. 75-78
-
-
Katze, M.G.1
-
17
-
-
0032557657
-
Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eIF2b
-
Kimball, S. R., J. R. Fabian, G. D. Pavitt, A. G. Hinnebusch, and L. S. Jefferson. 1998. Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eIF2b. J. Biol. Chem. 273:12841-12845.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12841-12845
-
-
Kimball, S.R.1
Fabian, J.R.2
Pavitt, G.D.3
Hinnebusch, A.G.4
Jefferson, L.S.5
-
18
-
-
0032579399
-
Identification of interprotein interactions between the subunits of eukaryotic initiation factors eIF2 and eIF2B
-
Kimball, S. R., N. K. Heinzinger, R. L. Horetsky, and L. S. Jefferson. 1998. Identification of interprotein interactions between the subunits of eukaryotic initiation factors eIF2 and eIF2B. J. Biol. Chem. 273:3039-3044.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3039-3044
-
-
Kimball, S.R.1
Heinzinger, N.K.2
Horetsky, R.L.3
Jefferson, L.S.4
-
19
-
-
0032052990
-
Expression and purification of the alpha-subunit of eukaryotic initiation factor eIF2: use as a kinase substrate
-
Kimball, S. R., R. L. Horetsky, R. Jagus, and L. S. Jefferson. 1998. Expression and purification of the alpha-subunit of eukaryotic initiation factor eIF2: use as a kinase substrate. Protein Expr. Purif. 12:415-419.
-
(1998)
Protein Expr. Purif.
, vol.12
, pp. 415-419
-
-
Kimball, S.R.1
Horetsky, R.L.2
Jagus, R.3
Jefferson, L.S.4
-
20
-
-
0026701570
-
Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase
-
Koromilas, A. E., S. Roy, G. N. Barber, M. G. Katze, and N. Sonenberg. 1992. Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science 257:1685-1689.
-
(1992)
Science
, vol.257
, pp. 1685-1689
-
-
Koromilas, A.E.1
Roy, S.2
Barber, G.N.3
Katze, M.G.4
Sonenberg, N.5
-
21
-
-
0034960171
-
Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
-
Krishnamoorthy, T., G. D. Pavitt, F. Zhang, T. E. Dever, and A. G. Hinnebusch. 2001. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation. Mol. Cell. Biol. 21:5018-5030.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5018-5030
-
-
Krishnamoorthy, T.1
Pavitt, G.D.2
Zhang, F.3
Dever, T.E.4
Hinnebusch, A.G.5
-
22
-
-
0025314596
-
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
-
Lazaris-Karatzas, A., K. S. Montine, and N. Sonenberg. 1990. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap. Nature 345:544-547.
-
(1990)
Nature
, vol.345
, pp. 544-547
-
-
Lazaris-Karatzas, A.1
Montine, K.S.2
Sonenberg, N.3
-
23
-
-
0026583874
-
The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts
-
Lazaris-Karatzas, A., and N. Sonenberg. 1992. The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts. Mol. Cell. Biol. 12:1234-1238.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 1234-1238
-
-
Lazaris-Karatzas, A.1
Sonenberg, N.2
-
24
-
-
18344386777
-
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter
-
Leegwater, P. A., et al. 2001. Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter. Nat. Genet. 29:383-388.
-
(2001)
Nat. Genet.
, vol.29
, pp. 383-388
-
-
Leegwater, P.A.1
-
25
-
-
0035166679
-
Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses
-
Lu, L., A. P. Han, and J. J. Chen. 2001. Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses. Mol. Cell. Biol. 21:7971-7980.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7971-7980
-
-
Lu, L.1
Han, A.P.2
Chen, J.J.3
-
26
-
-
0029968705
-
Initiation of protein synthesis in eukaryotic cells
-
Pain, V. M. 1996. Initiation of protein synthesis in eukaryotic cells. Eur. J. Biochem. 236:747-771.
-
(1996)
Eur. J. Biochem.
, vol.236
, pp. 747-771
-
-
Pain, V.M.1
-
27
-
-
0032519585
-
eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange
-
Pavitt, G. D., K. V. Ramaiah, S. R. Kimball, and A. G. Hinnebusch. 1998. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev. 12:514-526.
-
(1998)
Genes Dev
, vol.12
, pp. 514-526
-
-
Pavitt, G.D.1
Ramaiah, K.V.2
Kimball, S.R.3
Hinnebusch, A.G.4
-
28
-
-
0031020341
-
Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2
-
Pavitt, G. D., W. Yang, and A. G. Hinnebusch. 1997. Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2. Mol. Cell. Biol. 17: 1298-1313.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 1298-1313
-
-
Pavitt, G.D.1
Yang, W.2
Hinnebusch, A.G.3
-
29
-
-
1342304043
-
Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts
-
Perkins, D. J., and G. N. Barber. 2004. Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts. Mol. Cell. Biol. 24:2025-2040.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2025-2040
-
-
Perkins, D.J.1
Barber, G.N.2
-
30
-
-
0037112055
-
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
-
Pestova, T. V., and V. G. Kolupaeva. 2002. The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection. Genes Dev. 16:2906-2922.
-
(2002)
Genes Dev
, vol.16
, pp. 2906-2922
-
-
Pestova, T.V.1
Kolupaeva, V.G.2
-
31
-
-
0035912725
-
Molecular mechanisms of translation initiation in eukaryotes
-
Pestova, T. V., et al. 2001. Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl. Acad. Sci. U. S. A. 98:7029-7036.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 7029-7036
-
-
Pestova, T.V.1
-
32
-
-
33646058306
-
Vanishing white matter disease: a review with focus on its genetics
-
Pronk, J. C., B. van Kollenburg, G. C. Scheper, and M. S. van der Knaap. 2006. Vanishing white matter disease: a review with focus on its genetics. Ment. Retard. Dev. Disabil. Res. Rev. 12:123-128.
-
(2006)
Ment. Retard. Dev. Disabil. Res. Rev.
, vol.12
, pp. 123-128
-
-
Pronk, J.C.1
van Kollenburg, B.2
Scheper, G.C.3
van der Knaap, M.S.4
-
33
-
-
0028263821
-
Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation
-
Ramaiah, K. V., M. V. Davies, J. J. Chen, and R. J. Kaufman. 1994. Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation. Mol. Cell. Biol. 14:4546-4553.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4546-4553
-
-
Ramaiah, K.V.1
Davies, M.V.2
Chen, J.J.3
Kaufman, R.J.4
-
34
-
-
1542344340
-
Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity
-
Richardson, J. P., S. S. Mohammad, and G. D. Pavitt. 2004. Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity. Mol. Cell. Biol. 24:2352-2363.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2352-2363
-
-
Richardson, J.P.1
Mohammad, S.S.2
Pavitt, G.D.3
-
35
-
-
13444259647
-
Regulation of cap-dependent translation by eIF4E inhibitory proteins
-
Richter, J. D., and N. Sonenberg. 2005. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433:477-480.
-
(2005)
Nature
, vol.433
, pp. 477-480
-
-
Richter, J.D.1
Sonenberg, N.2
-
36
-
-
33749340583
-
An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation
-
Singh, C. R., et al. 2006. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation. EMBO J. 25:4537-4546.
-
(2006)
EMBO J
, vol.25
, pp. 4537-4546
-
-
Singh, C.R.1
-
37
-
-
0037311233
-
Eukaryotic translation initiation factors and regulators
-
Sonenberg, N., and T. E. Dever. 2003. Eukaryotic translation initiation factors and regulators. Curr. Opin. Struct. Biol. 13:56-63.
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 56-63
-
-
Sonenberg, N.1
Dever, T.E.2
-
39
-
-
33244482231
-
Regulation of protein synthesis in lymphoblasts from vanishing white matter patients
-
van Kollenburg, B., et al. 2006. Regulation of protein synthesis in lymphoblasts from vanishing white matter patients. Neurobiol. Dis. 21:496-504.
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 496-504
-
-
van Kollenburg, B.1
-
40
-
-
0000889541
-
Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation
-
Vazquez de Aldana, C. R., and A. G. Hinnebusch. 1994. Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation. Mol. Cell. Biol. 14:3208-3222.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3208-3222
-
-
Vazquez de Aldana, C.R.1
Hinnebusch, A.G.2
-
41
-
-
0030730131
-
Eukaryotic initiation factor 2B (eIF2B)
-
Webb, B. L., and C. G. Proud. 1997. Eukaryotic initiation factor 2B (eIF2B). Int. J. Biochem. Cell Biol. 29:1127-1131.
-
(1997)
Int. J. Biochem. Cell Biol.
, vol.29
, pp. 1127-1131
-
-
Webb, B.L.1
Proud, C.G.2
-
42
-
-
32544446451
-
Coping with stress: eIF2 kinases and translational control
-
Wek, R. C., H. Y. Jiang, and T. G. Anthony. 2006. Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans. 34:7-11.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 7-11
-
-
Wek, R.C.1
Jiang, H.Y.2
Anthony, T.G.3
-
43
-
-
0029006391
-
The histidyl-tRNA synthetaserelated sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids
-
Wek, S. A., S. Zhu, and R. C. Wek. 1995. The histidyl-tRNA synthetaserelated sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids. Mol. Cell. Biol. 15:4497-4506.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4497-4506
-
-
Wek, S.A.1
Zhu, S.2
Wek, R.C.3
-
44
-
-
0035816596
-
Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein
-
Williams, D. D., N. T. Price, A. J. Loughlin, and C. G. Proud. 2001. Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein. J. Biol. Chem. 276:24697-24703.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24697-24703
-
-
Williams, D.D.1
Price, N.T.2
Loughlin, A.J.3
Proud, C.G.4
-
45
-
-
0034028905
-
Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase
-
Yang, R., S. A. Wek, and R. C. Wek. 2000. Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase. Mol. Cell. Biol. 20:2706-2717.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2706-2717
-
-
Yang, R.1
Wek, S.A.2
Wek, R.C.3
-
46
-
-
0029805459
-
Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2
-
Yang, W., and A. G. Hinnebusch. 1996. Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2. Mol. Cell. Biol. 16:6603-6616.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6603-6616
-
-
Yang, W.1
Hinnebusch, A.G.2
|