Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease

Journal of Neuropathology and Experimental Neurology

Volumn 65, Issue 7, 2006, Pages 707-715

  Van Kollenburg, Barbara ^a   Van Dijk, Jantine ^a   Garbern, James ^c   Thomas, Adri A M ^d   Scheper, Gert C ^a   Powers, James M ^b   Van Der Knaap, Marjo S ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Childhood white matter disorders; Eukaryotic initiation factor 2B; Immunohistochemistry; qPCR; Unfolded protein response

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ASTROCYTE; BRAIN DISEASE; BRAIN TISSUE; CONTROLLED STUDY; GLIA CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SCHOOL CHILD; UNFOLDED PROTEIN RESPONSE; VANISHING WHITE MATTER DISEASE; WHITE MATTER; ALTERNATIVE RNA SPLICING; ANIMAL; CHILD; CYTOLOGY; DEMYELINATING DISEASE; ENDOPLASMIC RETICULUM; GENETICS; GLIA; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 PROTEIN, HUMAN; BIOLOGICAL MARKER; CHAPERONE; DNA BINDING PROTEIN; ERN2 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; MOLECULAR CHAPERONE GRP78; NUCLEAR PROTEIN; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; TRE BINDING PROTEIN; TRE-BINDING PROTEIN;

ACTIVATING TRANSCRIPTION FACTOR 6; ADOLESCENT; ADULT; ALTERNATIVE SPLICING; ANIMALS; BIOLOGICAL MARKERS; CHILD; DNA-BINDING PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; HEAT-SHOCK PROTEINS; HEREDITARY CENTRAL NERVOUS SYSTEM DEMYELINATING DISEASES; HUMANS; INFANT; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; NEUROGLIA; NUCLEAR PROTEINS; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 33747816491     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.jnen.0000228201.27539.50     Document Type: Article

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