Design, synthesis, characterization and biological evaluation of novel pyrazole integrated benzophenones

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 3, 2013, Pages 912-916

  Bandgar, Babasaheb P ^a   Chavan, Hemant V ^a   Adsul, Laxman K ^a   Thakare, Vishnu N ^b   Shringare, Sadanand N ^a   Shaikh, Rafik ^c   Gacche, Rajesh N ^c  

^a SOLAPUR UNIVERSITY   (India)

^b Sinhgad Institute of Pharmaceutical Sciences   (India)

^c SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY   (India)

Author keywords

Anti inflammatory; Antioxidant activity; Benzophenones; COSY; HMBC; HSQC; Pyrazole

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BENZOPHENONE DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; PYRAZOLE;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BENZOPHENONES; CELLS, CULTURED; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITORS; PYRAZOLES; RATS; STEREOISOMERISM;

RATTUS;

EID: 84872328448     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.031     Document Type: Article

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