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Volumn 52, Issue 7, 1996, Pages 1113-1125

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells

Author keywords

cyclooxygenase; inflammation; NSAID; phospholipase A2; prostaglandin; prostaglandin G H synthase

Indexed keywords

5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; 6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CALCIMYCIN; CALCIUM IONOPHORE; COMPLEMENTARY DNA; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; ISOENZYME; KETOROLAC; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SALICYLIC ACID;

EID: 0030580035     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00462-5     Document Type: Article
Times cited : (94)

References (44)
  • 1
    • 0028926813 scopus 로고
    • New insights into the mode of action of anti-inflammatory drugs
    • 1. Vane JR and Botting RM, New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 44: 1-10, 1995.
    • (1995) Inflamm Res , vol.44 , pp. 1-10
    • Vane, J.R.1    Botting, R.M.2
  • 2
    • 0011859555 scopus 로고
    • Prostaglandin and thromboxane biosynthesis
    • (Ed. Taylor CW), Pergamon Press, London
    • 2. Smith WL, Marnett LJ and DeWitt DL, Prostaglandin and thromboxane biosynthesis. In: Intracellular Messengers (Ed. Taylor CW), pp. 101-136. Pergamon Press, London, 1993.
    • (1993) Intracellular Messengers , pp. 101-136
    • Smith, W.L.1    Marnett, L.J.2    DeWitt, D.L.3
  • 3
    • 0026588961 scopus 로고
    • Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs
    • 3. Xie W, Robertson DL and Simmons DL, Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs. Drug Dev Res 25: 249-265, 1992.
    • (1992) Drug Dev Res , vol.25 , pp. 249-265
    • Xie, W.1    Robertson, D.L.2    Simmons, D.L.3
  • 4
    • 0028555837 scopus 로고
    • Regulation of prostaglandin synthase-1 and prostaglandin synthase-2
    • 4. Herschman HR, Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer Metastasis Rev 13: 241-256, 1994.
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 241-256
    • Herschman, H.R.1
  • 6
    • 0028959950 scopus 로고
    • Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression
    • 6. Goppelt-Struebe M, Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression. Prostaglandins Leukot Essent Fatty Acids 52: 212-222, 1995.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.52 , pp. 212-222
    • Goppelt-Struebe, M.1
  • 7
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
    • 7. O'Neill GP and Ford-Hutchinson AW, Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 330: 156-160, 1993.
    • (1993) FEBS Lett , vol.330 , pp. 156-160
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 8
    • 0027480087 scopus 로고
    • Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs
    • 8. Meade EA, Smith WL and DeWitt DL, Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal antiinflammatory drugs. J Biol Chem 268: 6610-6614, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 6610-6614
    • Meade, E.A.1    Smith, W.L.2    DeWitt, D.L.3
  • 12
    • 0028032723 scopus 로고
    • COX-1 and COX-2: Toward the development of more selective NSAIDs
    • 12. Battistini B, Botting R and Bakhle YS, COX-1 and COX-2: Toward the development of more selective NSAIDs. Drug News Perspect 7: 501-512, 1994.
    • (1994) Drug News Perspect , vol.7 , pp. 501-512
    • Battistini, B.1    Botting, R.2    Bakhle, Y.S.3
  • 13
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • 13. Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ and Vane JR, Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90: 11693-11697, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 14
    • 0027516402 scopus 로고
    • NS-398, a novel non-steroidal antiinflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
    • 14. Futaki N, Yoshikawa K, Hamasaka Y, Arai I, Higuchi S, Iizuka H and Otomo S, NS-398, a novel non-steroidal antiinflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. Gen Pharmacol 24: 104-110, 1993.
    • (1993) Gen Pharmacol , vol.24 , pp. 104-110
    • Futaki, N.1    Yoshikawa, K.2    Hamasaka, Y.3    Arai, I.4    Higuchi, S.5    Iizuka, H.6    Otomo, S.7
  • 17
    • 0028831977 scopus 로고
    • Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms
    • 17. Ouellet M and Percival MD, Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem J 306: 247-251, 1995.
    • (1995) Biochem J , vol.306 , pp. 247-251
    • Ouellet, M.1    Percival, M.D.2
  • 22
    • 0029029296 scopus 로고
    • Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDS and Cox 2 inhibitors
    • 22. Grossman CJ, Wiseman J, Lucas FS, Trevethick MA and Birch PJ, Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDS and Cox 2 inhibitors. Inflamm Res 44: 253-257, 1995.
    • (1995) Inflamm Res , vol.44 , pp. 253-257
    • Grossman, C.J.1    Wiseman, J.2    Lucas, F.S.3    Trevethick, M.A.4    Birch, P.J.5
  • 24
    • 0027986841 scopus 로고
    • Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal antiinflammatory drugs
    • 24. Laneuville O, Breuer DK, DeWitt DL, Hla T, Funk CD and Smith WL, Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal antiinflammatory drugs. J Pharmacol Exp Ther 271: 927-934, 1994.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 927-934
    • Laneuville, O.1    Breuer, D.K.2    DeWitt, D.L.3    Hla, T.4    Funk, C.D.5    Smith, W.L.6
  • 25
    • 0000151210 scopus 로고
    • Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by antiinflammatory drugs
    • 25. Rome LH and Lands WEM, Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by antiinflammatory drugs. Proc Natl Acad Sci USA 72: 4863-4865, 1975.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 4863-4865
    • Rome, L.H.1    Lands, W.E.M.2
  • 26
    • 11944265249 scopus 로고
    • High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification
    • 26. Cockett MI, Bebbington CR and Yarranton GT, High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. Biotechnology 8: 662-667, 1990.
    • (1990) Biotechnology , vol.8 , pp. 662-667
    • Cockett, M.I.1    Bebbington, C.R.2    Yarranton, G.T.3
  • 27
    • 0011887880 scopus 로고
    • Amplification using glutamine synthetase
    • (Eds. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA and Struhl J), John Wiley, New York
    • 27. Bebbington CR and Rolfe MR, Amplification using glutamine synthetase. In: Current Protocols in Molecular Biology (Eds. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA and Struhl J), pp. 16.4.7-16.14.13. John Wiley, New York, 1994.
    • (1994) Current Protocols in Molecular Biology , pp. 1647-161413
    • Bebbington, C.R.1    Rolfe, M.R.2
  • 28
    • 0000704627 scopus 로고
    • Transfection of DNA into eukaryotic cells: Calcium phosphate transfection
    • (Eds. Ausubel FM, Brent R, Kingston RE, Moore DE, Seidman JG, Smith JA and Struhl J), John Wiley, New York
    • 28. Kingston RE, Chen CA and Okayama H, Transfection of DNA into eukaryotic cells: Calcium phosphate transfection. In: Current Protocols in Molecular Biology (Eds. Ausubel FM, Brent R, Kingston RE, Moore DE, Seidman JG, Smith JA and Struhl J), pp. 9.1.1-9.1.9. John Wiley, New York, 1994.
    • (1994) Current Protocols in Molecular Biology , pp. 911-919
    • Kingston, R.E.1    Chen, C.A.2    Okayama, H.3
  • 30
    • 0029071691 scopus 로고
    • Expression-activity profiles of cells transfected with prostaglandin endoperoxide H synthase measured by quantitative fluorescence microscopy
    • 30. Morita I, Smith WL, DeWitt DL and Schindler M, Expression-activity profiles of cells transfected with prostaglandin endoperoxide H synthase measured by quantitative fluorescence microscopy. Biochemistry 34: 7194-7199, 1995.
    • (1995) Biochemistry , vol.34 , pp. 7194-7199
    • Morita, I.1    Smith, W.L.2    DeWitt, D.L.3    Schindler, M.4
  • 32
    • 0028199075 scopus 로고
    • Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
    • 32. Reddy SR and Hreschman HR, Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J Biol Chem 269: 15473-15480, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 15473-15480
    • Reddy, S.R.1    Hreschman, H.R.2
  • 34
    • 0028020545 scopus 로고
    • 2 by antisense and effects on endotoxin-induced prostaglandin biosynthesis
    • 2 by antisense and effects on endotoxin-induced prostaglandin biosynthesis. J Biol Chem 269: 25999-26005, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 25999-26005
    • Roshak, A.1    Sathe, G.2    Marshall, L.A.3
  • 35
    • 0029072559 scopus 로고
    • Tepoxalin, a novel dual inhibitor of the prostaglandin-H synthase cyclooxygenase and peroxidase activities
    • 35. Tam SSC, Lee DHS, Wang EY, Munroe DG and Lau CY, Tepoxalin, a novel dual inhibitor of the prostaglandin-H synthase cyclooxygenase and peroxidase activities. J Biol Chem 270: 13948-13955, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 13948-13955
    • Tam, S.S.C.1    Lee, D.H.S.2    Wang, E.Y.3    Munroe, D.G.4    Lau, C.Y.5
  • 36
    • 0030043909 scopus 로고    scopus 로고
    • 2 and distal prostaglandin synthase I
    • 2 and distal prostaglandin synthase I. J Biol Chem 271: 186-191, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 186-191
    • Reddy, S.T.1    Herschman, H.R.2
  • 38
    • 0019596906 scopus 로고
    • Kinen-induced prostaglandin synthesis by renal papillary collecting tubule cells in culture
    • 38. Grenier FC, Rollins TE and Smith WL, Kinen-induced prostaglandin synthesis by renal papillary collecting tubule cells in culture. Am J Physiol 241: F94-F104, 1981.
    • (1981) Am J Physiol , vol.241
    • Grenier, F.C.1    Rollins, T.E.2    Smith, W.L.3
  • 40
    • 0029020361 scopus 로고
    • 2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen
    • 2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen. J Biol Chem 270: 15359-15367, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 15359-15367
    • Glover, S.1    Bayburt, T.2    Jonas, M.3    Chi, E.4    Gelb, M.H.5
  • 42
    • 0027369679 scopus 로고
    • Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes
    • 42. DeWitt DL and Meade EA, Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes. Arch Biochem Biophys 306: 94-102, 1993.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 94-102
    • DeWitt, D.L.1    Meade, E.A.2
  • 43
    • 0027469850 scopus 로고
    • Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells
    • 43. Kujubu DA, Reddy ST, Fletcher BS and Herschman HR, Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells. J Biol Chem 268: 5425-5430, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 5425-5430
    • Kujubu, D.A.1    Reddy, S.T.2    Fletcher, B.S.3    Herschman, H.R.4
  • 44
    • 0024363551 scopus 로고
    • Topography of prostaglandin H synthase: Antiinflammatory agents and the protease-sensitive arginine 253 region
    • 44. Kulmacz RJ, Topography of prostaglandin H synthase: Antiinflammatory agents and the protease-sensitive arginine 253 region. J Biol Chem 264: 14136-14144, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 14136-14144
    • Kulmacz, R.J.1


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